The NMDA receptor as a target for cognitive enhancement
Collingridge, Graham L., Volianskis, Arturas, Bannister, Neil, France, Grace, Hanna, Lydia, Mercier, Marion, Tidball, Patrick, Fang, Guangyu, Irvine, Mark W., Costa, Blaise M., Monaghan, Daniel T., Bortolotto, Zuner A., Molnár, Elek, Lodge, David, Jane, David E.
Published in Neuropharmacology (01.01.2013)
Published in Neuropharmacology (01.01.2013)
Get full text
Journal Article
In the Telencephalon, GluN2C NMDA Receptor Subunit mRNA is Predominately Expressed in Glial Cells and GluN2D mRNA in Interneurons
Alsaad, Hassan A., DeKorver, Nicholas W., Mao, Zhihao, Dravid, Shashank M., Arikkath, Jyothi, Monaghan, Daniel T.
Published in Neurochemical research (01.01.2019)
Published in Neurochemical research (01.01.2019)
Get full text
Journal Article
NMDA receptors containing GluN2C and GluN2D subunits have opposing roles in modulating neuronal oscillations; potential mechanism for bidirectional feedback
Mao, Zhihao, He, Shengxi, Mesnard, Christopher, Synowicki, Paul, Zhang, Yuning, Chung, Lucy, Wiesman, Alex I., Wilson, Tony W., Monaghan, Daniel T.
Published in Brain research (15.01.2020)
Published in Brain research (15.01.2020)
Get full text
Journal Article
The NMDA receptor GluN2C subunit controls cortical excitatory-inhibitory balance, neuronal oscillations and cognitive function
Gupta, Subhash C., Ravikrishnan, Aparna, Liu, Jinxu, Mao, Zhihao, Pavuluri, Ratnamala, Hillman, Brandon G., Gandhi, Pauravi J., Stairs, Dustin J., Li, Ming, Ugale, Rajesh R., Monaghan, Daniel T., Dravid, Shashank M.
Published in Scientific reports (06.12.2016)
Published in Scientific reports (06.12.2016)
Get full text
Journal Article
Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors
Wang, Jue Xiang, Irvine, Mark W., Burnell, Erica S., Sapkota, Kiran, Thatcher, Robert J., Li, Minjun, Simorowski, Noriko, Volianskis, Arturas, Collingridge, Graham L., Monaghan, Daniel T., Jane, David E., Furukawa, Hiro
Published in Nature communications (22.01.2020)
Published in Nature communications (22.01.2020)
Get full text
Journal Article
Different NMDA receptor subtypes mediate induction of long‐term potentiation and two forms of short‐term potentiation at CA1 synapses in rat hippocampus in vitro
Volianskis, Arturas, Bannister, Neil, Collett, Valerie J., Irvine, Mark W., Monaghan, Daniel T., Fitzjohn, Stephen M., Jensen, Morten S., Jane, David E., Collingridge, Graham L.
Published in The Journal of physiology (01.02.2013)
Published in The Journal of physiology (01.02.2013)
Get full text
Journal Article
Extrasynaptic NR2B and NR2D subunits of NMDA receptors shape ‘superslow’ afterburst EPSC in rat hippocampus
Lozovaya, Natasha A., Grebenyuk, Sergei E., Tsintsadze, Timur Sh, Feng, Bihua, Monaghan, Daniel T., Krishtal, Oleg A.
Published in The Journal of physiology (15.07.2004)
Published in The Journal of physiology (15.07.2004)
Get full text
Journal Article
N-Methyl-d-aspartate (NMDA) Receptor NR2 Subunit Selectivity of a Series of Novel Piperazine-2,3-dicarboxylate Derivatives: Preferential Blockade of Extrasynaptic NMDA Receptors in the Rat Hippocampal CA3-CA1 Synapse
Costa, Blaise Mathias, Feng, Bihua, Tsintsadze, Timur S, Morley, Richard M, Irvine, Mark W, Tsintsadze, Vera, Lozovaya, Natasha A, Jane, David E, Monaghan, Daniel T
Published in The Journal of pharmacology and experimental therapeutics (01.11.2009)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2009)
Get full text
Journal Article
Structure–activity analysis of a novel NR2C/NR2D‐preferring NMDA receptor antagonist: 1‐(phenanthrene‐2‐carbonyl) piperazine‐2,3‐dicarboxylic acid
Feng, Bihua, Tse, Heong W, Skifter, Donald A, Morley, Richard, Jane, David E, Monaghan, Daniel T
Published in British journal of pharmacology (01.02.2004)
Published in British journal of pharmacology (01.02.2004)
Get full text
Journal Article
Selective inhibition of GluN2D-containing N-methyl-D-aspartate receptors prevents tissue plasminogen activator-promoted neurotoxicity both in vitro and in vivo
Jullienne, Amandine, Montagne, Axel, Orset, Cyrille, Lesept, Flavie, Jane, David E, Monaghan, Daniel T, Maubert, Eric, Vivien, Denis, Ali, Carine
Published in Molecular neurodegeneration (05.10.2011)
Published in Molecular neurodegeneration (05.10.2011)
Get full text
Journal Article
Piperazine-2,3-dicarboxylic Acid Derivatives as Dual Antagonists of NMDA and GluK1-Containing Kainate Receptors
Irvine, Mark W, Costa, Blaise M, Dlaboga, Daniel, Culley, Georgia R, Hulse, Richard, Scholefield, Caroline L, Atlason, Palmi, Fang, Guangyu, Eaves, Richard, Morley, Richard, Mayo-Martin, Maria B, Amici, Mascia, Bortolotto, Zuner A, Donaldson, Lucy, Collingridge, Graham L, Molnár, Elek, Monaghan, Daniel T, Jane, David E
Published in Journal of medicinal chemistry (12.01.2012)
Published in Journal of medicinal chemistry (12.01.2012)
Get full text
Journal Article
Positive and Negative Allosteric Modulators of N‑Methyl‑d‑aspartate (NMDA) Receptors: Structure–Activity Relationships and Mechanisms of Action
Burnell, Erica S, Irvine, Mark, Fang, Guangyu, Sapkota, Kiran, Jane, David E, Monaghan, Daniel T
Published in Journal of medicinal chemistry (10.01.2019)
Published in Journal of medicinal chemistry (10.01.2019)
Get full text
Journal Article
Synthesis and Pharmacology of N -Substituted Piperazine-2,3-dicarboxylic Acid Derivatives Acting as NMDA Receptor Antagonists
Morley, Richard M, Tse, Heong-Wai, Feng, Bihua, Miller, Jacqueline C, Monaghan, Daniel T, Jane, David E
Published in Journal of medicinal chemistry (07.04.2005)
Published in Journal of medicinal chemistry (07.04.2005)
Get full text
Journal Article
An Antisense Oligonucleotide to the N-Methyl-d-aspartate (NMDA) Subunit NMDAR1 Attenuates NMDA-Induced Nociception, Hyperalgesia, and Morphine Tolerance
Shimoyama, Naohito, Shimoyama, Megumi, Davis, Antonia M, Monaghan, Daniel T, Inturrisi, Charles E
Published in The Journal of pharmacology and experimental therapeutics (01.02.2005)
Published in The Journal of pharmacology and experimental therapeutics (01.02.2005)
Get full text
Journal Article
Pharmacological characterization of a novel negative allosteric modulator of NMDA receptors, UBP792
Sapkota, Kiran, Burnell, Erica S., Irvine, Mark W., Fang, Guangyu, Gawande, Dinesh Y., Dravid, Shashank M., Jane, David E., Monaghan, Daniel T.
Published in Neuropharmacology (15.12.2021)
Published in Neuropharmacology (15.12.2021)
Get full text
Journal Article
The NMDA receptor intracellular C-terminal domains reciprocally interact with allosteric modulators
Sapkota, Kiran, Dore, Kim, Tang, Kang, Irvine, Mark, Fang, Guangyu, Burnell, Erica S., Malinow, Roberto, Jane, David E., Monaghan, Daniel T.
Published in Biochemical pharmacology (01.01.2019)
Published in Biochemical pharmacology (01.01.2019)
Get full text
Journal Article
Identification of Subunit- and Antagonist-Specific Amino Acid Residues in the N-Methyl-d-aspartate Receptor Glutamate-Binding Pocket
Kinarsky, Leo, Feng, Bihua, Skifter, Donald A, Morley, Richard M, Sherman, Simon, Jane, David E, Monaghan, Daniel T
Published in The Journal of pharmacology and experimental therapeutics (01.06.2005)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2005)
Get full text
Journal Article