T cell activation induces a noncoding RNA transcript sensitive to inhibition by immunosuppressant drugs and encoded by the proto-oncogene, BIC
Haasch, Deanna, Chen, Yung-Wu, Reilly, Regina M, Grace Chiou, X, Koterski, Sandra, Smith, Morey L, Kroeger, Paul, McWeeny, Kerri, Halbert, Donald N, Mollison, Karl W, Djuric, Stevan W, Trevillyan, James M
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Published in Cellular immunology (01.05.2002)
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Efficacies of ABT-773, a New Ketolide, against Experimental Bacterial Infections
MITTEN, M. J, MEULBROEK, J, OR, Y. S, MA, Z, NILIUS, A. M, MOLLISON, K, FLAMM, R. K, NUKKALA, M, PAIGE, L, JARVIS, K, OLEKSIJEW, A, TOVCIMAK, A, HERNANDEZ, L, ALDER, J. D, EWING, P
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Potent Inhibition of NFAT Activation and T Cell Cytokine Production by Novel Low Molecular Weight Pyrazole Compounds
Trevillyan, James M., Chiou, X. Grace, Chen, Yung-Wu, Ballaron, Stephen J., Sheets, Michael P., Smith, Morey L., Wiedeman, Paul E., Warrior, Usha, Wilkins, Julie, Gubbins, Earl J., Gagne, Gerard D., Fagerland, Jane, Carter, George W., Luly, Jay R., Mollison, Karl W., Djuric, Stevan W.
Published in The Journal of biological chemistry (21.12.2001)
Published in The Journal of biological chemistry (21.12.2001)
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3,5-Bis(trifluoromethyl)pyrazoles: A Novel Class of NFAT Transcription Factor Regulator
Djuric, Stevan W, BaMaung, Nwe Y, Basha, Anwer, Liu, Huaqing, Luly, Jay R, Madar, David J, Sciotti, Richard J, Tu, Noah P, Wagenaar, Frank L, Wiedeman, Paul E, Zhou, Xun, Ballaron, Stephen, Bauch, Joy, Chen, Yung-Wu, Chiou, X. Grace, Fey, Thomas, Gauvin, Donna, Gubbins, Earl, Hsieh, Gin C, Marsh, Kennan C, Mollison, Karl W, Pong, Melissa, Shaughnessy, Thomas K, Sheets, Michael P, Smith, Morey, Trevillyan, James M, Warrior, Usha, Wegner, Craig D, Carter, George W
Published in Journal of medicinal chemistry (10.08.2000)
Published in Journal of medicinal chemistry (10.08.2000)
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Identification of Receptor-Binding Residues in the Inflammatory Complement Protein C5a by Site-Directed Mutagenesis
Mollison, Karl W., Mandecki, Wlodek, Erik R. P. Zuiderweg, Fayer, Lisbeth, Fey, Thomas A., Krause, Ruth A., Conway, Richard G., Miller, Loan, Edalji, Rohinton P., Shallcross, Mary Ann, Lane, Benjamin, Fox, J. Lawrence, Greer, Jonathan, Carter, George W.
Published in Proceedings of the National Academy of Sciences - PNAS (01.01.1989)
Published in Proceedings of the National Academy of Sciences - PNAS (01.01.1989)
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New Antimitotic Agents with Activity in Multi-Drug-Resistant Cell Lines and in Vivo Efficacy in Murine Tumor Models
Szczepankiewicz, Bruce G, Liu, Gang, Jae, Hwan-Soo, Tasker, Andrew S, Gunawardana, Indrani W, von Geldern, Thomas W, Gwaltney, Stephen L, Wu-Wong, J. Ruth, Gehrke, Laura, Chiou, William J, Credo, R. Bruce, Alder, Jeffery D, Nukkala, Michael A, Zielinski, Nicolette A, Jarvis, Ken, Mollison, Karl W, Frost, David J, Bauch, Joy L, Hui, Yu Hua, Claiborne, Akiyo K, Li, Qun, Rosenberg, Saul H
Published in Journal of medicinal chemistry (06.12.2001)
Published in Journal of medicinal chemistry (06.12.2001)
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Synthesis and immunosuppressant activity of pyrazole carboxamides
Wang, Alan X., Xie, Qinghua, Lane, Ben, Mollison, Karl W., Hsieh, Gin C., Marsh, Kennan, Sheets, Michael P., Luly, Jay R., Coghlan, Michael J.
Published in Bioorganic & medicinal chemistry letters (06.10.1998)
Published in Bioorganic & medicinal chemistry letters (06.10.1998)
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32-Ascomycinyloxyacetic Acid Derived Immunosuppressants. Independence of Immunophilin Binding and Immunosuppressive Potency
Wagner, Rolf, Rhoades, Teresa A, Or, Yat Sun, Lane, Benjamin C, Hsieh, Gin, Mollison, Karl W, Luly, Jay R
Published in Journal of medicinal chemistry (21.05.1998)
Published in Journal of medicinal chemistry (21.05.1998)
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A Macrolactam Inhibitor of T Helper Type 1 and T Helper Type 2 Cytokine Biosynthesis for Topical Treatment of Inflammatory Skin Diseases
MOLLISON, K. W, FEY, T. A, CANNON, J, MARSH, K, CARTER, G. W, OR, Y.-S, CHEN, Y.-W, HSIEH, G. C, LULY, J. R, GAUVIN, D. M, KOLANO, R. M, SHEETS, M. P, SMITH, M. L, PONG, M, NIKOLAIDIS, N. M, LANE, B. C, TREVILLYAN, J. M
Published in Journal of investigative dermatology (01.05.1999)
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Identification and synthesis of a receptor binding site of human anaphylatoxin C5a
Kawai, Megumi, Quincy, David A, Lane, Benjamin, Mollison, Karl W, Luly, Jay R, Carter, George W
Published in Journal of medicinal chemistry (01.07.1991)
Published in Journal of medicinal chemistry (01.07.1991)
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Retention of Immunosuppressant Activity in an Ascomycin Analogue Lacking a Hydrogen-Bonding Interaction with FKBP12
Wiedeman, Paul E, Fesik, Stephen W, Petros, Andrew M, Nettesheim, David G, Mollison, Karl W, Lane, Benjamin C, Or, Yat Sun, Luly, Jay R
Published in Journal of medicinal chemistry (21.10.1999)
Published in Journal of medicinal chemistry (21.10.1999)
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Studies on an immunosuppressive macrolactam, ascomycin: Synthesis of a C-33 hydroxyl derivative
Kawai, Megumi, Gunawardana, Indrani W.K., Mollison, Karl W., Hsieh, Gin C., Lane, Benjamin C., Luly, Jay R.
Published in Bioorganic & medicinal chemistry letters (21.04.1998)
Published in Bioorganic & medicinal chemistry letters (21.04.1998)
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Nephrotoxicity studies of the immunosuppressants tacrolimus (FK506) and ascomycin in rat models
Mollison, Karl W, Fey, Thomas A, Krause, Ruth A, Andrews, Janet M, Bretheim, Pat T, Cusick, Patrick K, Hsieh, Gin C, Luly, Jay R
Published in Toxicology (Amsterdam) (06.02.1998)
Published in Toxicology (Amsterdam) (06.02.1998)
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Group B streptococci inactivate complement component C5a by enzymic cleavage at the C-terminus
BOHNSACK, J. F, MOLLISON, K. W, BUKO, A. M, ASHWORTH, J. C, HILL, H. R
Published in Biochemical journal (01.02.1991)
Published in Biochemical journal (01.02.1991)
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Secondary Structure of Complement Component C3a Anaphylatoxin in Solution as Determined by NMR Spectroscopy: Differences between Crystal and Solution Conformations
Nettesheim, David G., Edalji, Rohinton P., Mollison, Karl W., Greer, Jonathan, Erik R. P. Zuiderweg
Published in Proceedings of the National Academy of Sciences - PNAS (01.07.1988)
Published in Proceedings of the National Academy of Sciences - PNAS (01.07.1988)
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Discovery of FK 506 analogues that are nontoxic to mouse pancreatic beta cells in vitro but show diabetogenic potential when administered to the rat
Mollison, K W, Andrews, J M, Fey, T A, Miller, L N, Krause, R A, Bretheim, P T, Brandt, J A, Wagner, R, Lane, B C, Hsieh, G C, Luly, J R
Published in Transplantation proceedings (01.12.1996)
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Published in Transplantation proceedings (01.12.1996)
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Inhibition of p56(lck) tyrosine kinase by isothiazolones
Trevillyan, J M, Chiou, X G, Ballaron, S J, Tang, Q M, Buko, A, Sheets, M P, Smith, M L, Putman, C B, Wiedeman, P, Tu, N, Madar, D, Smith, H T, Gubbins, E J, Warrior, U P, Chen, Y W, Mollison, K W, Faltynek, C R, Djurić, S W
Published in Archives of biochemistry and biophysics (01.04.1999)
Published in Archives of biochemistry and biophysics (01.04.1999)
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