Targeting the dynamic HSP90 complex in cancer
Neckers, Len, Trepel, Jane, Mollapour, Mehdi, Giaccone, Giuseppe
Published in Nature reviews. Cancer (01.08.2010)
Published in Nature reviews. Cancer (01.08.2010)
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Journal Article
Post-translational modifications of Hsp90 and translating the chaperone code
Backe, Sarah J., Sager, Rebecca A., Woodford, Mark R., Makedon, Alan M., Mollapour, Mehdi
Published in The Journal of biological chemistry (07.08.2020)
Published in The Journal of biological chemistry (07.08.2020)
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Journal Article
Structure and function of the co-chaperone protein phosphatase 5 in cancer
Sager, Rebecca A., Dushukyan, Natela, Woodford, Mark, Mollapour, Mehdi
Published in Cell stress & chaperones (01.05.2020)
Published in Cell stress & chaperones (01.05.2020)
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Journal Article
Epichaperomics reveals dysfunctional chaperone protein networks
Woodford, Mark R., Bourboulia, Dimitra, Mollapour, Mehdi
Published in Nature communications (22.08.2023)
Published in Nature communications (22.08.2023)
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Journal Article
The tumor suppressor folliculin inhibits lactate dehydrogenase A and regulates the Warburg effect
Woodford, Mark R., Baker-Williams, Alexander J., Sager, Rebecca A., Backe, Sarah J., Blanden, Adam R., Hashmi, Fiza, Kancherla, Priyanka, Gori, Alessandro, Loiselle, David R., Castelli, Matteo, Serapian, Stefano A., Colombo, Giorgio, Haystead, Timothy A., Jensen, Sandra M., Stetler-Stevenson, William G., Loh, Stewart N., Schmidt, Laura S., Linehan, W. Marston, Bah, Alaji, Bourboulia, Dimitra, Bratslavsky, Gennady, Mollapour, Mehdi
Published in Nature structural & molecular biology (01.08.2021)
Published in Nature structural & molecular biology (01.08.2021)
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Journal Article
Co-chaperones TIMP2 and AHA1 Competitively Regulate Extracellular HSP90:Client MMP2 Activity and Matrix Proteolysis
Baker-Williams, Alexander J., Hashmi, Fiza, Budzyński, Marek A., Woodford, Mark R., Gleicher, Stephanie, Himanen, Samu V., Makedon, Alan M., Friedman, Derek, Cortes, Stephanie, Namek, Sara, Stetler-Stevenson, William G., Bratslavsky, Gennady, Bah, Alaji, Mollapour, Mehdi, Sistonen, Lea, Bourboulia, Dimitra
Published in Cell reports (Cambridge) (13.08.2019)
Published in Cell reports (Cambridge) (13.08.2019)
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Journal Article
Hsp90 phosphorylation, Wee1 and the cell cycle
Mollapour, Mehdi, Tsutsumi, Shinji, Neckers, Len
Published in Cell cycle (Georgetown, Tex.) (15.06.2010)
Published in Cell cycle (Georgetown, Tex.) (15.06.2010)
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Journal Article
Therapeutic potential of CDK4/6 inhibitors in renal cell carcinoma
Sager, Rebecca A., Backe, Sarah J., Ahanin, Elham, Smith, Garrett, Nsouli, Imad, Woodford, Mark R., Bratslavsky, Gennady, Bourboulia, Dimitra, Mollapour, Mehdi
Published in Nature reviews. Urology (01.05.2022)
Published in Nature reviews. Urology (01.05.2022)
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Journal Article
PhosY-secretome profiling combined with kinase-substrate interaction screening defines active c-Src-driven extracellular signaling
Backe, Sarah J., Votra, SarahBeth D., Stokes, Matthew P., Sebestyén, Endre, Castelli, Matteo, Torielli, Luca, Colombo, Giorgio, Woodford, Mark R., Mollapour, Mehdi, Bourboulia, Dimitra
Published in Cell reports (Cambridge) (27.06.2023)
Published in Cell reports (Cambridge) (27.06.2023)
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Journal Article
TRAP1 Chaperones the Metabolic Switch in Cancer
Wengert, Laura A., Backe, Sarah J., Bourboulia, Dimitra, Mollapour, Mehdi, Woodford, Mark R.
Published in Biomolecules (Basel, Switzerland) (04.06.2022)
Published in Biomolecules (Basel, Switzerland) (04.06.2022)
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Journal Article
Fumarate Hydratase Deficiency in Renal Cancer Induces Glycolytic Addiction and Hypoxia-Inducible Transcription Factor 1α Stabilization by Glucose-Dependent Generation of Reactive Oxygen Species
Sudarshan, Sunil, Sourbier, Carole, Kong, Hye-Sik, Block, Karen, Romero, Vladimir A. Valera, Yang, Youfeng, Galindo, Cynthia, Mollapour, Mehdi, Scroggins, Bradley, Goode, Norman, Lee, Min-Jung, Gourlay, Campbell W., Trepel, Jane, Linehan, W. Marston, Neckers, Len
Published in Molecular and Cellular Biology (01.08.2009)
Published in Molecular and Cellular Biology (01.08.2009)
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Journal Article
Activation of autophagy depends on Atg1/Ulk1-mediated phosphorylation and inhibition of the Hsp90 chaperone machinery
Backe, Sarah J., Sager, Rebecca A., Heritz, Jennifer A., Wengert, Laura A., Meluni, Katherine A., Aran-Guiu, Xavier, Panaretou, Barry, Woodford, Mark R., Prodromou, Chrisostomos, Bourboulia, Dimitra, Mollapour, Mehdi
Published in Cell reports (Cambridge) (25.07.2023)
Published in Cell reports (Cambridge) (25.07.2023)
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Journal Article
Charged linker sequence modulates eukaryotic heat shock protein 90 (Hsp90) chaperone activity
Tsutsumi, Shinji, Mollapour, Mehdi, Prodromou, Chrisostomos, Lee, Chung-Tien, Panaretou, Barry, Yoshida, Soichiro, Mayer, Matthias P, Neckers, Leonard M
Published in Proceedings of the National Academy of Sciences - PNAS (21.02.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (21.02.2012)
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Journal Article
The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding
Woodford, Mark R., Dunn, Diana M., Blanden, Adam R., Capriotti, Dante, Loiselle, David, Prodromou, Chrisostomos, Panaretou, Barry, Hughes, Philip F., Smith, Aaron, Ackerman, Wendi, Haystead, Timothy A., Loh, Stewart N., Bourboulia, Dimitra, Schmidt, Laura S., Marston Linehan, W., Bratslavsky, Gennady, Mollapour, Mehdi
Published in Nature communications (29.06.2016)
Published in Nature communications (29.06.2016)
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Journal Article
Post-translational Regulation of FNIP1 Creates a Rheostat for the Molecular Chaperone Hsp90
Sager, Rebecca A., Woodford, Mark R., Backe, Sarah J., Makedon, Alan M., Baker-Williams, Alexander J., DiGregorio, Bryanna T., Loiselle, David R., Haystead, Timothy A., Zachara, Natasha E., Prodromou, Chrisostomos, Bourboulia, Dimitra, Schmidt, Laura S., Linehan, W. Marston, Bratslavsky, Gennady, Mollapour, Mehdi
Published in Cell reports (Cambridge) (29.01.2019)
Published in Cell reports (Cambridge) (29.01.2019)
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Journal Article
Activation of autophagy depends on Atg1/Ulk1-mediated phosphorylation and inhibition of the Hsp90 chaperone machinery
Backe, Sarah J., Sager, Rebecca A., Heritz, Jennifer A., Wengert, Laura A., Meluni, Katherine A., Aran-Guiu, Xavier, Panaretou, Barry, Woodford, Mark R., Prodromou, Chrisostomos, Bourboulia, Dimitra, Mollapour, Mehdi
Published in Cell reports (Cambridge) (23.01.2024)
Published in Cell reports (Cambridge) (23.01.2024)
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Journal Article
Design of Disruptors of the Hsp90-Cdc37 Interface
D'Annessa, Ilda, Hurwitz, Naama, Pirota, Valentina, Beretta, Giovanni Luca, Tinelli, Stella, Woodford, Mark, Freccero, Mauro, Mollapour, Mehdi, Zaffaroni, Nadia, Wolfson, Haim, Colombo, Giorgio
Published in Molecules (Basel, Switzerland) (15.01.2020)
Published in Molecules (Basel, Switzerland) (15.01.2020)
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Journal Article
Phosphorylation and Ubiquitination Regulate Protein Phosphatase 5 Activity and Its Prosurvival Role in Kidney Cancer
Dushukyan, Natela, Dunn, Diana M., Sager, Rebecca A., Woodford, Mark R., Loiselle, David R., Daneshvar, Michael, Baker-Williams, Alexander J., Chisholm, John D., Truman, Andrew W., Vaughan, Cara K., Haystead, Timothy A., Bratslavsky, Gennady, Bourboulia, Dimitra, Mollapour, Mehdi
Published in Cell reports (Cambridge) (14.11.2017)
Published in Cell reports (Cambridge) (14.11.2017)
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