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O'Hayre, M, Inoue, A, Kufareva, I, Wang, Z, Mikelis, C M, Drummond, R A, Avino, S, Finkel, K, Kalim, K W, DiPasquale, G, Guo, F, Aoki, J, Zheng, Y, Lionakis, M S, Molinolo, A A, Gutkind, J S
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Hippo-Independent Activation of YAP by the GNAQ Uveal Melanoma Oncogene through a Trio-Regulated Rho GTPase Signaling Circuitry
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Szabo, R, Rasmussen, A L, Moyer, A B, Kosa, P, Schafer, J M, Molinolo, A A, Gutkind, J S, Bugge, T H
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Published in Journal of bone and mineral research (01.07.2012)
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Transcriptional signature primes human oral mucosa for rapid wound healing
Iglesias-Bartolome, Ramiro, Uchiyama, Akihiko, Molinolo, Alfredo A, Abusleme, Loreto, Brooks, Stephen R, Callejas-Valera, Juan Luis, Edwards, Dean, Doci, Colleen, Asselin-Labat, Marie-Liesse, Onaitis, Mark W, Moutsopoulos, Niki M, Gutkind, J S, Morasso, Maria I
Published in Science translational medicine (25.07.2018)
Published in Science translational medicine (25.07.2018)
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Gilardi, Mara, Wang, Zhiyong, Proietto, Marco, Chillà, Anastasia, Calleja-Valera, Juan Luis, Goto, Yusuke, Vanoni, Marco, Janes, Matthew R, Mikulski, Zbigniew, Gualberto, Antonio, Molinolo, Alfredo A, Ferrara, Napoleone, Gutkind, J Silvio, Burrows, Francis
Published in Molecular cancer therapeutics (01.09.2020)
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Suppressing neutrophil-dependent angiogenesis abrogates resistance to anti-VEGF antibody in a genetic model of colorectal cancer
Itatani, Yoshiro, Yamamoto, Takamasa, Zhong, Cuiling, Molinolo, Alfredo A., Ruppel, Jane, Hegde, Priti, Taketo, M. Mark, Ferrara, Napoleone
Published in Proceedings of the National Academy of Sciences - PNAS (01.09.2020)
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Tumor-induced osteomalacia
Chong, William H, Molinolo, Alfredo A, Chen, Clara C, Collins, Michael T
Published in Endocrine-related cancer (01.06.2011)
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Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4
Wang, Zhiyong, Wu, Victoria H., Allevato, Michael M., Gilardi, Mara, He, Yudou, Luis Callejas-Valera, Juan, Vitale-Cross, Lynn, Martin, Daniel, Amornphimoltham, Panomwat, Mcdermott, James, Yung, Bryan S., Goto, Yusuke, Molinolo, Alfredo A., Sharabi, Andrew B., Cohen, Ezra E. W., Chen, Qianming, Lyons, J. Guy, Alexandrov, Ludmil B., Gutkind, J. Silvio
Published in Nature communications (05.12.2019)
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Detecting cancer metastasis and accompanying protein biomarkers at single cell levels using a 3D-printed microfluidic immunoarray
Sharafeldin, Mohamed, Chen, Tianqi, Ozkaya, Gulsum Ucak, Choudhary, Dharamainder, Molinolo, Alfredo A., Gutkind, J. Silvio, Rusling, James F.
Published in Biosensors & bioelectronics (01.01.2021)
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Assembly and activation of the Hippo signalome by FAT1 tumor suppressor
Martin, Daniel, Degese, Maria S., Vitale-Cross, Lynn, Iglesias-Bartolome, Ramiro, Valera, Juan Luis Callejas, Wang, Zhiyong, Feng, Xiaodong, Yeerna, Huwate, Vadmal, Vachan, Moroishi, Toshiro, Thorne, Rick F., Zaida, Moraima, Siegele, Bradford, Cheong, Sok C., Molinolo, Alfredo A., Samuels, Yardena, Tamayo, Pablo, Guan, Kun Liang, Lippman, Scott M., Lyons, J. Guy, Gutkind, J. Silvio
Published in Nature communications (09.07.2018)
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Lymphatic-preserving treatment sequencing with immune checkpoint inhibition unleashes cDC1-dependent antitumor immunity in HNSCC
Saddawi-Konefka, Robert, O’Farrell, Aoife, Faraji, Farhoud, Clubb, Lauren, Allevato, Michael M., Jensen, Shawn M., Yung, Bryan S., Wang, Zhiyong, Wu, Victoria H., Anang, Nana-Ama, Msari, Riyam Al, Schokrpur, Shiruyeh, Pietryga, Ida Franiak, Molinolo, Alfredo A., Mesirov, Jill P., Simon, Aaron B., Fox, Bernard A., Bui, Jack D., Sharabi, Andrew, Cohen, Ezra E. W., Califano, Joseph A., Gutkind, J. Silvio
Published in Nature communications (25.07.2022)
Published in Nature communications (25.07.2022)
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HPV E2, E4, E5 drive alternative carcinogenic pathways in HPV positive cancers
Ren, Shuling, Gaykalova, Daria A., Guo, Theresa, Favorov, Alexander V., Fertig, Elana J., Tamayo, Pablo, Callejas-Valera, Juan Luis, Allevato, Mike, Gilardi, Mara, Santos, Jessica, Fukusumi, Takahito, Sakai, Akihiro, Ando, Mizuo, Sadat, Sayed, Liu, Chao, Xu, Guorong, Fisch, Kathleen M., Wang, Zhiyong, Molinolo, Alfredo A., Gutkind, J. Silvio, Ideker, Trey, Koch, Wayne M., Califano, Joseph A.
Published in Oncogene (01.10.2020)
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The head and neck cancer cell oncogenome: a platform for the development of precision molecular therapies
Martin, Daniel, Abba, Martin C, Molinolo, Alfredo A, Vitale-Cross, Lynn, Wang, Zhiyong, Zaida, Moraima, Delic, Naomi C, Samuels, Yardena, Lyons, J Guy, Gutkind, J Silvio
Published in Oncotarget (15.10.2014)
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4E-BP1 Is a Tumor Suppressor Protein Reactivated by mTOR Inhibition in Head and Neck Cancer
Wang, Zhiyong, Feng, Xiaodong, Molinolo, Alfredo A, Martin, Daniel, Vitale-Cross, Lynn, Nohata, Nijiro, Ando, Mizuo, Wahba, Amy, Amornphimoltham, Panomwat, Wu, Xingyu, Gilardi, Mara, Allevato, Michael, Wu, Victoria, Steffen, Dana J, Tofilon, Philip, Sonenberg, Nahum, Califano, Joseph, Chen, Qianming, Lippman, Scott M, Gutkind, J Silvio
Published in Cancer research (Chicago, Ill.) (01.04.2019)
Published in Cancer research (Chicago, Ill.) (01.04.2019)
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Disruption of the HER3-PI3K-mTOR oncogenic signaling axis and PD-1 blockade as a multimodal precision immunotherapy in head and neck cancer
Wang, Zhiyong, Goto, Yusuke, Allevato, Michael M., Wu, Victoria H., Saddawi-Konefka, Robert, Gilardi, Mara, Alvarado, Diego, Yung, Bryan S., O’Farrell, Aoife, Molinolo, Alfredo A., Duvvuri, Umamaheswar, Grandis, Jennifer R., Califano, Joseph A., Cohen, Ezra E. W., Gutkind, J. Silvio
Published in Nature communications (22.04.2021)
Published in Nature communications (22.04.2021)
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mTOR as a Molecular Target in HPV-Associated Oral and Cervical Squamous Carcinomas
MOLINOLO, Alfredo A, MARSH, Christina, DINALI, Mohamed El, GANGANE, Nitin, JENNISON, Kaitlin, HEWITT, Stephen, PATEL, Vyomesh, SEIWERT, Tanguy Y, GUTKIND, J. Silvio
Published in Clinical cancer research (01.05.2012)
Published in Clinical cancer research (01.05.2012)
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mTOR co-targeting in cetuximab resistance in head and neck cancers harboring PIK3CA and RAS mutations
Wang, Zhiyong, Martin, Daniel, Molinolo, Alfredo A, Patel, Vyomesh, Iglesias-Bartolome, Ramiro, Degese, Maria Sol, Vitale-Cross, Lynn, Chen, Qianming, Gutkind, J Silvio
Published in JNCI : Journal of the National Cancer Institute (01.09.2014)
Published in JNCI : Journal of the National Cancer Institute (01.09.2014)
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