Discovery and Optimization of Macrocyclic Quinoxaline-pyrrolo-dihydropiperidinones as Potent Pim-1/2 Kinase Inhibitors
Cee, Victor J, Chavez, Frank, Herberich, Bradley, Lanman, Brian A, Pettus, Liping H, Reed, Anthony B, Wu, Bin, Wurz, Ryan P, Andrews, Kristin L, Chen, Jie, Hickman, Dean, Laszlo, Jimmy, Lee, Matthew R, Guerrero, Nadia, Mattson, Bethany K, Nguyen, Yen, Mohr, Christopher, Rex, Karen, Sastri, Christine E, Wang, Paul, Wu, Qiong, Wu, Tian, Xu, Yang, Zhou, Yihong, Winston, Jeffrey T, Lipford, J. Russell, Tasker, Andrew S, Wang, Hui-Ling
Published in ACS medicinal chemistry letters (14.04.2016)
Published in ACS medicinal chemistry letters (14.04.2016)
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Discovery and Evaluation of 7-Alkyl-1,5-bis-aryl-pyrazolopyridinones as Highly Potent, Selective, and Orally Efficacious Inhibitors of p38 alpha Mitogen-Activated Protein Kinase
Pettus, Liping H., Wurz, Ryan P., Xu, Shimin, Herberich, Brad, Henkle, Bradley, Liu, Qiurong, McBride, Helen J., Mu, Sharon, Plant, Matthew H., Saris, Christiaan J. M., Sherman, Lisa, Wong, Lu Min, Chmait, Samer, Lee, Matthew R., Mohr, Christopher, Hsieh, Faye, Tasker, Andrew S.
Published in Journal of medicinal chemistry (08.04.2010)
Published in Journal of medicinal chemistry (08.04.2010)
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Discovery of N -(1-Acryloylazetidin-3-yl)-2-(1 H -indol-1-yl)acetamides as Covalent Inhibitors of KRAS G12C
Shin, Youngsook, Jeong, Joon Won, Wurz, Ryan P, Achanta, Pragathi, Arvedson, Tara, Bartberger, Michael D, Campuzano, Iain D G, Fucini, Ray, Hansen, Stig K, Ingersoll, John, Iwig, Jeffrey S, Lipford, J Russell, Ma, Vu, Kopecky, David J, McCarter, John, San Miguel, Tisha, Mohr, Christopher, Sabet, Sudi, Saiki, Anne Y, Sawayama, Andrew, Sethofer, Steven, Tegley, Christopher M, Volak, Laurie P, Yang, Kevin, Lanman, Brian A, Erlanson, Daniel A, Cee, Victor J
Published in ACS medicinal chemistry letters (12.09.2019)
Published in ACS medicinal chemistry letters (12.09.2019)
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Discovery of N‑(1-Acryloylazetidin-3-yl)-2-(1H‑indol-1-yl)acetamides as Covalent Inhibitors of KRASG12C
Shin, Youngsook, Jeong, Joon Won, Wurz, Ryan P, Achanta, Pragathi, Arvedson, Tara, Bartberger, Michael D, Campuzano, Iain D. G, Fucini, Ray, Hansen, Stig K, Ingersoll, John, Iwig, Jeffrey S, Lipford, J. Russell, Ma, Vu, Kopecky, David J, McCarter, John, San Miguel, Tisha, Mohr, Christopher, Sabet, Sudi, Saiki, Anne Y, Sawayama, Andrew, Sethofer, Steven, Tegley, Christopher M, Volak, Laurie P, Yang, Kevin, Lanman, Brian A, Erlanson, Daniel A, Cee, Victor J
Published in ACS medicinal chemistry letters (12.09.2019)
Published in ACS medicinal chemistry letters (12.09.2019)
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Peptide Ligands of pp60c-src SH2 Domains: A Thermodynamic and Structural Study
Charifson, Paul S, Shewchuk, Lisa M, Rocque, Warren, Hummel, Conrad W, Jordan, Steven R, Mohr, Christopher, Pacofsky, Gregory J, Peel, Michael R, Rodriguez, Marc, Sternbach, Daniel D, Consler, Thomas G
Published in Biochemistry (Easton) (27.05.1997)
Published in Biochemistry (Easton) (27.05.1997)
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PAC1 항체 및 이의 용도
FUCHSLOCHER BRYNA, GRAHAM KEVIN, WALKER KENNETH WILLIAM, CHONG SU, WANG ZHULUN, HAMBURGER AGNES EVA, MICHAELS MARK LEO, PIPER DEREK E, MOHR CHRISTOPHER, CHEN IRWIN, XU CEN, AGRAWAL NEERAJ JAGDISH
Year of Publication 23.09.2020
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Year of Publication 23.09.2020
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qPortal – A science gateway for biomedical applications
Mohr, Christopher, Friedrich, Andreas, Wojnar, David, Kenar, Erhan, Aydin Can Polatkan, Codrea, Marius Cosmin, Czemmel, Stefan, Kohlbacher, Oliver, Nahnsen, Sven
Published in PeerJ preprints (01.03.2017)
Published in PeerJ preprints (01.03.2017)
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Pyridyl-pyrimidine benzimidazole derivatives as potent, selective, and orally bioavailable inhibitors of Tie-2 kinase
Cee, Victor J., Cheng, Alan C., Romero, Karina, Bellon, Steve, Mohr, Christopher, Whittington, Douglas A., Bak, Annette, Bready, James, Caenepeel, Sean, Coxon, Angela, Deak, Holly L., Fretland, Jenne, Gu, Yan, Hodous, Brian L., Huang, Xin, Kim, Joseph L., Lin, Jasmine, Long, Alexander M., Nguyen, Hanh, Olivieri, Philip R., Patel, Vinod F., Wang, Ling, Zhou, Yihong, Hughes, Paul, Geuns-Meyer, Stephanie
Published in Bioorganic & medicinal chemistry letters (15.01.2009)
Published in Bioorganic & medicinal chemistry letters (15.01.2009)
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Oculo-auriculo-vertebral spectrum (OAVS): clinical evaluation and severity scoring of 53 patients and proposal for a new classification
Tasse, Christiane, Böhringer, Stefan, Fischer, Sven, Lüdecke, Hermann-Josef, Albrecht, Beate, Horn, Denise, Janecke, Andreas, Kling, Rainer, König, Rainer, Lorenz, Birgit, Majewski, Frank, Maeyens, Elisabeth, Meinecke, Peter, Mitulla, Beate, Mohr, Christopher, Preischl, Monika, Umstadt, Horst, Kohlhase, Jürgen, Gillessen-Kaesbach, Gabriele, Wieczorek, Dagmar
Published in European journal of medical genetics (01.10.2005)
Published in European journal of medical genetics (01.10.2005)
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Part 2: Structure–activity relationship (SAR) investigations of fused pyrazoles as potent, selective and orally available inhibitors of p38α mitogen-activated protein kinase
Wurz, Ryan P., Pettus, Liping H., Henkle, Bradley, Sherman, Lisa, Plant, Matthew, Miner, Kent, McBride, Helen J., Wong, Lu Min, Saris, Christiaan J.M., Lee, Matthew R., Chmait, Samer, Mohr, Christopher, Hsieh, Faye, Tasker, Andrew S.
Published in Bioorganic & medicinal chemistry letters (01.03.2010)
Published in Bioorganic & medicinal chemistry letters (01.03.2010)
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Reconstructive oral and maxillofacial surgery
Hölzle, Frank, Wolff, Klaus-Dietrich, Mohr, Christopher
Published in Deutsches Ärzteblatt international (01.11.2008)
Published in Deutsches Ärzteblatt international (01.11.2008)
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Part 1: Structure–Activity Relationship (SAR) investigations of fused pyrazoles as potent, selective and orally available inhibitors of p38α mitogen-activated protein kinase
Wurz, Ryan P., Pettus, Liping H., Xu, Shimin, Henkle, Bradley, Sherman, Lisa, Plant, Matthew, Miner, Kent, McBride, Helen, Wong, Lu Min, Saris, Christiaan J.M., Lee, Matthew R., Chmait, Samer, Mohr, Christopher, Hsieh, Faye, Tasker, Andrew S.
Published in Bioorganic & medicinal chemistry letters (15.08.2009)
Published in Bioorganic & medicinal chemistry letters (15.08.2009)
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Discovery of ligands for Nurr1 by combined use of NMR screening with different isotopic and spin-labeling strategies
Poppe, Leszek, Harvey, Timothy S, Mohr, Christopher, Zondlo, James, Tegley, Christopher M, Nuanmanee, Opas, Cheetham, Janet
Published in Journal of biomolecular screening (01.04.2007)
Published in Journal of biomolecular screening (01.04.2007)
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Identification of triazolopyridazinones as potent p38α inhibitors
Herberich, Brad, Jackson, Claire, Wurz, Ryan P., Pettus, Liping H., Sherman, Lisa, Liu, Qiurong, Henkle, Bradley, Saris, Christiaan J.M., Wong, Lu Min, Chmait, Samer, Lee, Matthew R., Mohr, Christopher, Hsieh, Faye, Tasker, Andrew S.
Published in Bioorganic & medicinal chemistry letters (15.01.2012)
Published in Bioorganic & medicinal chemistry letters (15.01.2012)
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Part 2: Structure-activity relationship (SAR) investigations of fused pyrazoles as potent, selective and orally available inhibitors of p38a mitogen-activated protein kinase
Wurz, Ryan P, Pettus, Liping H, Henkle, Bradley, Sherman, Lisa, Plant, Matthew, Miner, Kent, McBride, Helen J, Wong, Lu Min, Saris, Christiaan JM, Lee, Matthew R, Chmait, Samer, Mohr, Christopher, Hsieh, Faye, Tasker, Andrew S
Published in Bioorganic & medicinal chemistry letters (01.03.2010)
Published in Bioorganic & medicinal chemistry letters (01.03.2010)
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Discovery and Evaluation of 7-Alkyl-1,5-bis-aryl-pyrazolopyridinones as Highly Potent, Selective, and Orally Efficacious Inhibitors of p38α Mitogen-Activated Protein Kinase ⊥ Atomic coordinates and structure factors for crystal structure of compound 3d with p38α can be accessed using PDB code 3LHJ
Pettus, Liping H, Wurz, Ryan P, Xu, Shimin, Herberich, Brad, Henkle, Bradley, Liu, Qiurong, McBride, Helen J, Mu, Sharon, Plant, Matthew H, Saris, Christiaan J. M, Sherman, Lisa, Wong, Lu Min, Chmait, Samer, Lee, Matthew R, Mohr, Christopher, Hsieh, Faye, Tasker, Andrew S
Published in Journal of medicinal chemistry (08.04.2010)
Published in Journal of medicinal chemistry (08.04.2010)
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