Evolution of enzyme catalysts caged in biomimetic gel-shell beads
Fischlechner, Martin, Schaerli, Yolanda, Mohamed, Mark F., Patil, Santosh, Abell, Chris, Hollfelder, Florian
Published in Nature chemistry (01.09.2014)
Published in Nature chemistry (01.09.2014)
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Ultrahigh-throughput discovery of promiscuous enzymes by picodroplet functional metagenomics
Colin, Pierre-Yves, Kintses, Balint, Gielen, Fabrice, Miton, Charlotte M., Fischer, Gerhard, Mohamed, Mark F., Hyvönen, Marko, Morgavi, Diego P., Janssen, Dick B, Hollfelder, Florian
Published in Nature communications (07.12.2015)
Published in Nature communications (07.12.2015)
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Picoliter Cell Lysate Assays in Microfluidic Droplet Compartments for Directed Enzyme Evolution
Kintses, Balint, Hein, Christopher, Mohamed, Mark F., Fischlechner, Martin, Courtois, Fabienne, Lainé, Céline, Hollfelder, Florian
Published in Chemistry & biology (24.08.2012)
Published in Chemistry & biology (24.08.2012)
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Balancing Specificity and Promiscuity in Enzyme Evolution: Multidimensional Activity Transitions in the Alkaline Phosphatase Superfamily
van Loo, Bert, Bayer, Christopher D, Fischer, Gerhard, Jonas, Stefanie, Valkov, Eugene, Mohamed, Mark F, Vorobieva, Anastassia, Dutruel, Celine, Hyvönen, Marko, Hollfelder, Florian
Published in Journal of the American Chemical Society (09.01.2019)
Published in Journal of the American Chemical Society (09.01.2019)
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Transition-State Interactions in a Promiscuous Enzyme: Sulfate and Phosphate Monoester Hydrolysis by Pseudomonas aeruginosa Arylsulfatase
van Loo, Bert, Berry, Ryan, Boonyuen, Usa, Mohamed, Mark F, Golicnik, Marko, Hengge, Alvan C, Hollfelder, Florian
Published in Biochemistry (Easton) (12.03.2019)
Published in Biochemistry (Easton) (12.03.2019)
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Evolutionary repurposing of a sulfatase: A new Michaelis complex leads to efficient transition state charge offset
Miton, Charlotte M., Jonas, Stefanie, Fischer, Gerhard, Duarte, Fernanda, Mohamed, Mark F., van Loo, Bert, Kintses, Bálint, Kamerlin, Shina C. L., Tokuriki, Nobuhiko, Hyvönen, Marko, Hollfelder, Florian
Published in Proceedings of the National Academy of Sciences - PNAS (31.07.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (31.07.2018)
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Combination of a Dinuclear Zn2+ Complex and a Medium Effect Exerts a 1012-Fold Rate Enhancement of Cleavage of an RNA and DNA Model System
Neverov, Alexei A, Lu, Zhong-Lin, Maxwell, Christopher I, Mohamed, Mark F, White, Christopher J, Tsang, Josephine S. W, Brown, R. Stan
Published in Journal of the American Chemical Society (20.12.2006)
Published in Journal of the American Chemical Society (20.12.2006)
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Combination of a dinuclear Zn2+ complex and a medium effect exerts a 10(12)-fold rate enhancement of cleavage of an RNA and DNA model system
Neverov, Alexei A, Lu, Zhong-Lin, Maxwell, Christopher I, Mohamed, Mark F, White, Christopher J, Tsang, Josephine S W, Brown, R Stan
Published in Journal of the American Chemical Society (20.12.2006)
Published in Journal of the American Chemical Society (20.12.2006)
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Potentiometric Titration of Metal Ions in Ethanol
Gibson, Graham T. T, Mohamed, Mark F, Neverov, Alexei A, Brown, R. S
Published in Inorganic chemistry (18.09.2006)
Published in Inorganic chemistry (18.09.2006)
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Solvent induced cooperativity of Zn(ii) complexes cleaving a phosphate diester RNA analog in methanolElectronic supplementary information (ESI) available: Tables and Figures giving various kobsvs. [catalyst] rate constant data for cleavage of 1 as well as the 1H NMR spectrum of 4. See DOI: 10.1039/c1ob06482g
Mohamed, Mark F, Snchez-Lombardo, Irma, Neverov, Alexei A, Brown, R. Stan
Year of Publication 15.12.2011
Year of Publication 15.12.2011
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Methanolysis of organophosphorus esters promoted by an M^sup 2+^ catalyst supported on polystyrene-based copolymers
Didier, Benoit, Mohamed, Mark F, Csaszar, Elizabeth, Colizza, Kate G, Neverov, Alexei A, Brown, R Stan
Published in Canadian journal of chemistry (01.02.2008)
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Published in Canadian journal of chemistry (01.02.2008)
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