Effect of upper gastrointestinal disease on the pharmacokinetics of oral semaglutide in subjects with type 2 diabetes
Meier, Juris J., Granhall, Charlotte, Hoevelmann, Ulrike, Navarria, Andrea, Plum‐Moerschel, Leona, Ramesh, Chethana, Tannapfel, Andrea, Kapitza, Christoph
Published in Diabetes, obesity & metabolism (01.04.2022)
Published in Diabetes, obesity & metabolism (01.04.2022)
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Journal Article
Novel hepato‐preferential basal insulin peglispro (BIL) does not differentially affect insulin sensitivity compared with insulin glargine in patients with type 1 and type 2 diabetes
Porksen, Niels, Linnebjerg, Helle, Garhyan, Parag, Lam, Eric C. Q., Knadler, Mary P., Jacober, Scott J., Hoevelmann, Ulrike, Plum‐Moerschel, Leona, Watkins, Elaine, Gastaldelli, Amalia, Heise, Tim
Published in Diabetes, obesity & metabolism (01.04.2017)
Published in Diabetes, obesity & metabolism (01.04.2017)
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Journal Article
Efficacy and safety of oral basal insulin versus subcutaneous insulin glargine in type 2 diabetes: a randomised, double-blind, phase 2 trial
Halberg, Inge B, Lyby, Karsten, Wassermann, Karsten, Heise, Tim, Zijlstra, Eric, Plum-Mörschel, Leona
Published in The lancet. Diabetes & endocrinology (01.03.2019)
Published in The lancet. Diabetes & endocrinology (01.03.2019)
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Journal Article
MEDI0382, a GLP-1 and glucagon receptor dual agonist, in obese or overweight patients with type 2 diabetes: a randomised, controlled, double-blind, ascending dose and phase 2a study
Ambery, Philip, Parker, Victoria E, Stumvoll, Michael, Posch, Maximilian G, Heise, Tim, Plum-Moerschel, Leona, Tsai, Lan-Feng, Robertson, Darren, Jain, Meena, Petrone, Marcella, Rondinone, Cristina, Hirshberg, Boaz, Jermutus, Lutz
Published in The Lancet (British edition) (30.06.2018)
Published in The Lancet (British edition) (30.06.2018)
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Journal Article
Validation of a Novel Method for Determining the Renal Threshold for Glucose Excretion in Untreated and Canagliflozin-treated Subjects With Type 2 Diabetes Mellitus
Polidori, David, Sha, Sue, Ghosh, Atalanta, Plum-Mörschel, Leona, Heise, Tim, Rothenberg, Paul
Published in The journal of clinical endocrinology and metabolism (01.05.2013)
Published in The journal of clinical endocrinology and metabolism (01.05.2013)
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Journal Article
Oral insulin: A history of ambition, failure and data torturing
Heise, Tim, Plum‐Mörschel, Leona, Zijlstra, Eric
Published in Diabetes, obesity & metabolism (01.04.2023)
Published in Diabetes, obesity & metabolism (01.04.2023)
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Journal Article
The Effect of Food Intake on the Pharmacokinetics of Oral Basal Insulin: A Randomised Crossover Trial in Healthy Male Subjects
Halberg, Inge B., Lyby, Karsten, Wassermann, Karsten, Heise, Tim, Plum-Mörschel, Leona, Zijlstra, Eric
Published in Clinical pharmacokinetics (01.11.2019)
Published in Clinical pharmacokinetics (01.11.2019)
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Journal Article
Dasiglucagon-A Next-Generation Glucagon Analog for Rapid and Effective Treatment of Severe Hypoglycemia: Results of Phase 3 Randomized Double-Blind Clinical Trial
Pieber, Thomas R, Aronson, Ronnie, Hövelmann, Ulrike, Willard, Julie, Plum-Mörschel, Leona, Knudsen, Kim M, Bandak, Benedikte, Tehranchi, Ramin
Published in Diabetes care (01.06.2021)
Published in Diabetes care (01.06.2021)
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Journal Article
Efficacy, Safety, and Mechanistic Insights of Cotadutide, a Dual Receptor Glucagon-Like Peptide-1 and Glucagon Agonist
Parker, Victoria E R, Robertson, Darren, Wang, Tao, Hornigold, David C, Petrone, Marcella, Cooper, Aidan T, Posch, Maximilian G, Heise, Tim, Plum-Moerschel, Leona, Schlichthaar, Heike, Klaus, Beate, Ambery, Philip D, Meier, Juris J, Hirshberg, Boaz
Published in The journal of clinical endocrinology and metabolism (01.03.2020)
Published in The journal of clinical endocrinology and metabolism (01.03.2020)
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Journal Article
Phase I studies of the safety, tolerability, pharmacokinetics and pharmacodynamics of the dual glucagon receptor/glucagon‐like peptide‐1 receptor agonist BI 456906
Jungnik, Arvid, Arrubla Martinez, Jorge, Plum‐Mörschel, Leona, Kapitza, Christoph, Lamers, Daniela, Thamer, Claus, Schölch, Corinna, Desch, Michael, Hennige, Anita M.
Published in Diabetes, obesity & metabolism (01.04.2023)
Published in Diabetes, obesity & metabolism (01.04.2023)
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Journal Article
Phase I Study of Glucagon-like Peptide-1/ Glucagon Receptor Dual Agonist BI 456906 in Obesity
Arrubla, Jorge, Schoelch, Corinna, Plum-Moerschel, Leona, Kapitza, Christoph, Lamers, Daniela, Thamer, Claus, Hennige, Anita M
Published in Obesity (Silver Spring, Md.) (01.12.2021)
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Published in Obesity (Silver Spring, Md.) (01.12.2021)
Journal Article
Pharmacokinetics and Glucodynamics of Ultra Rapid Lispro (URLi) versus Humalog® (Lispro) in Younger Adults and Elderly Patients with Type 1 Diabetes Mellitus: A Randomised Controlled Trial
Linnebjerg, Helle, Zhang, Qianyi, LaBell, Elizabeth, Dellva, Mary Anne, Coutant, David E., Hövelmann, Ulrike, Plum-Mörschel, Leona, Herbrand, Theresa, Leohr, Jennifer
Published in Clinical pharmacokinetics (01.12.2020)
Published in Clinical pharmacokinetics (01.12.2020)
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Journal Article
822-P: Influence of the Functionally Selective Insulin Analog NNC-965 vs. Insulin Glargine (IGla) on Cardiac Structure and Function
Jordan, Jens, Gerlach, Darius, Haraldsson, Henrik, Heise, Tim, Herbrand, Theresa, Lyby, Karsten, Tank, Jens, Nishimura, Erica, Plum-Moerschel, Leona, Thórisdóttir, Ólöf, Johansson, Lars
Published in Diabetes (New York, N.Y.) (01.06.2024)
Published in Diabetes (New York, N.Y.) (01.06.2024)
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Journal Article
Safety, tolerability, pharmacodynamics and pharmacokinetics following once‐daily doses of BI 187004, an inhibitor of 11 beta‐hydroxysteroid dehydrogenase‐1, over 28 days in patients with type 2 diabetes mellitus and overweight or obesity
Bianzano, Susanna, Nordaby, Matias, Plum‐Mörschel, Leona, Peil, Barbara, Heise, Tim
Published in Diabetes, obesity & metabolism (01.03.2023)
Published in Diabetes, obesity & metabolism (01.03.2023)
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Journal Article
Selective Inhibition of 11beta-Hydroxysteroiddehydrogenase-1 with BI 187004 in Patients with Type 2 Diabetes and Overweight or Obesity: Safety, Pharmacokinetics, and Pharmacodynamics After Multiple Dosing Over 14 Days
Bianzano, Susanna, Schepers, Cornelia, Wolff, Michael, Heise, Tim, Plum-Moerschel, Leona
Published in Experimental and clinical endocrinology & diabetes (01.12.2022)
Published in Experimental and clinical endocrinology & diabetes (01.12.2022)
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Journal Article
Euglycaemic glucose clamp: what it can and cannot do, and how to do it
Heise, Tim, Zijlstra, Eric, Nosek, Leszek, Heckermann, Sascha, Plum-Mörschel, Leona, Forst, Thomas
Published in Diabetes, obesity & metabolism (01.10.2016)
Published in Diabetes, obesity & metabolism (01.10.2016)
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Journal Article
Ready-to-use Dasiglucagon Injection as a Rapid and Effective Treatment for Severe Hypoglycemia
Pieber, Thomas, Tehranchi, Ramin, Hövelmann, Ulrike, Willard, Julie, Plum-Moerschel, Leona, Kendall, David, Aronson, Ronnie
Published in Metabolism, clinical and experimental (01.03.2021)
Published in Metabolism, clinical and experimental (01.03.2021)
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Journal Article
Editorial: evolution of GLP‐1 receptor agonists as pharmacotherapy for NASH beyond diabetes mellitus and obesity – authors’ reply
Flint, Anne, Andersen, Grit, Hockings, Paul, Plum‐Mörschel, Leona, Loomba, Rohit
Published in Alimentary pharmacology & therapeutics (01.12.2021)
Published in Alimentary pharmacology & therapeutics (01.12.2021)
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Journal Article
740-P: Proposed Biosimilar Gan & Lee Insulin Glargine (GL-GLA) Shows Pharmacokinetic (PK) and Pharmacodynamic (PD) Bioequivalence (BE) to U.S.- and EU-Licensed Insulin Glargine (IG)
HEISE, TIM, PLUM-MOERSCHEL, LEONA, ANDERSEN, GRIT, LU, JIA, WILSON, MICHAEL G., ZIJLSTRA, ERIC
Published in Diabetes (New York, N.Y.) (01.06.2021)
Published in Diabetes (New York, N.Y.) (01.06.2021)
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Journal Article
736-P: Proposed Biosimilar Gan & Lee Insulin Lispro (GL-LIS) Shows Pharmacokinetic (PK) and Pharmacodynamic (PD) Bioequivalence (BE) vs. U.S.- and EU-Licensed Insulin Lispro (LIS)
ZIJLSTRA, ERIC, HEISE, TIM, ERMER, MARCEL, LU, JIA, WILSON, MICHAEL G., PLUM-MOERSCHEL, LEONA
Published in Diabetes (New York, N.Y.) (01.06.2021)
Published in Diabetes (New York, N.Y.) (01.06.2021)
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Journal Article