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Japanese version of The Cancer Genome Atlas, JCGA, established using fresh frozen tumors obtained from 5143 cancer patients

Japanese version of The Cancer Genome Atlas, JCGA, established using fresh frozen tumors obtained from 5143 cancer patients

by Nagashima, Takeshi, Yamaguchi, Ken, Urakami, Kenichi, Shimoda, Yuji, Ohnami, Sumiko, Ohshima, Keiichi, Tanabe, Tomoe, Naruoka, Akane, Kamada, Fukumi, Serizawa, Masakuni, Hatakeyama, Keiichi, Matsumura, Kenya, Ohnami, Shumpei, Maruyama, Koji, Mochizuki, Tohru, Kusuhara, Masatoshi, Shiomi, Akio, Ohde, Yasuhisa, Terashima, Masanori, Uesaka, Katsuhiko, Onitsuka, Tetsuro, Nishimura, Seiichiro, Hirashima, Yasuyuki, Hayashi, Nakamasa, Kiyohara, Yoshio, Tsubosa, Yasuhiro, Katagiri, Hirohisa, Niwakawa, Masashi, Takahashi, Kaoru, Kashiwagi, Hiroya, Nakagawa, Masahiro, Ishida, Yuji, Sugino, Takashi, Takahashi, Mitsuru, Akiyama, Yasuto
Published in Cancer science (01.02.2020)

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Let-7 microRNA family is selectively secreted into the extracellular environment via exosomes in a metastatic gastric cancer cell line

Let-7 microRNA family is selectively secreted into the extracellular environment via exosomes in a metastatic gastric cancer cell line

by Ohshima, Keiichi, Inoue, Kanako, Fujiwara, Akemi, Hatakeyama, Keiichi, Kanto, Kaori, Watanabe, Yuko, Muramatsu, Koji, Fukuda, Yorikane, Ogura, Shun-ichiro, Yamaguchi, Ken, Mochizuki, Tohru
Published in PloS one (08.10.2010)

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Integrated analysis of gene expression and copy number identified potential cancer driver genes with amplification-dependent overexpression in 1,454 solid tumors

Integrated analysis of gene expression and copy number identified potential cancer driver genes with amplification-dependent overexpression in 1,454 solid tumors

by Ohshima, Keiichi, Hatakeyama, Keiichi, Nagashima, Takeshi, Watanabe, Yuko, Kanto, Kaori, Doi, Yuki, Ide, Tomomi, Shimoda, Yuji, Tanabe, Tomoe, Ohnami, Sumiko, Ohnami, Shumpei, Serizawa, Masakuni, Maruyama, Koji, Akiyama, Yasuto, Urakami, Kenichi, Kusuhara, Masatoshi, Mochizuki, Tohru, Yamaguchi, Ken
Published in Scientific reports (04.04.2017)

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Driver gene alterations and activated signaling pathways toward malignant progression of gastrointestinal stromal tumors

Driver gene alterations and activated signaling pathways toward malignant progression of gastrointestinal stromal tumors

by Ohshima, Keiichi, Fujiya, Keiichi, Nagashima, Takeshi, Ohnami, Sumiko, Hatakeyama, Keiichi, Urakami, Kenichi, Naruoka, Akane, Watanabe, Yuko, Moromizato, Sachi, Shimoda, Yuji, Ohnami, Shumpei, Serizawa, Masakuni, Akiyama, Yasuto, Kusuhara, Masatoshi, Mochizuki, Tohru, Sugino, Takashi, Shiomi, Akio, Tsubosa, Yasuhiro, Uesaka, Katsuhiko, Terashima, Masanori, Yamaguchi, Ken
Published in Cancer science (01.12.2019)

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Tumor cell enrichment by tissue suspension enables detection of mutations with low variant allele frequency and estimation of germline mutations

Tumor cell enrichment by tissue suspension enables detection of mutations with low variant allele frequency and estimation of germline mutations

by Hatakeyama, Keiichi, Muramatsu, Koji, Nagashima, Takeshi, Kawanishi, Yuichi, Fukumura, Ryutaro, Ohshima, Keiichi, Shimoda, Yuji, Kenmotsu, Hirotsugu, Mochizuki, Tohru, Urakami, Kenichi, Akiyama, Yasuto, Sugino, Takashi, Yamaguchi, Ken
Published in Scientific reports (22.02.2022)

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Mutational burden and signatures in 4000 Japanese cancers provide insights into tumorigenesis and response to therapy

Mutational burden and signatures in 4000 Japanese cancers provide insights into tumorigenesis and response to therapy

by Hatakeyama, Keiichi, Nagashima, Takeshi, Ohshima, Keiichi, Ohnami, Sumiko, Ohnami, Shumpei, Shimoda, Yuji, Serizawa, Masakuni, Maruyama, Koji, Naruoka, Akane, Akiyama, Yasuto, Urakami, Kenichi, Kusuhara, Masatoshi, Mochizuki, Tohru, Yamaguchi, Ken
Published in Cancer science (01.08.2019)

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Characterization of tumors with ultralow tumor mutational burden in Japanese cancer patients

Characterization of tumors with ultralow tumor mutational burden in Japanese cancer patients

by Hatakeyama, Keiichi, Nagashima, Takeshi, Ohshima, Keiichi, Ohnami, Sumiko, Ohnami, Shumpei, Shimoda, Yuji, Naruoka, Akane, Maruyama, Koji, Iizuka, Akira, Ashizawa, Tadashi, Mochizuki, Tohru, Urakami, Kenichi, Akiyama, Yasuto, Yamaguchi, Ken
Published in Cancer science (01.10.2020)

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Tumor mutational burden analysis of 2,000 Japanese cancer genomes using whole exome and targeted gene panel sequencing

Tumor mutational burden analysis of 2,000 Japanese cancer genomes using whole exome and targeted gene panel sequencing

by HATAKEYAMA, Keiichi, NAGASHIMA, Takeshi, URAKAMI, Kenichi, OHSHIMA, Keiichi, SERIZAWA, Masakuni, OHNAMI, Sumiko, SHIMODA, Yuji, OHNAMI, Shumpei, MARUYAMA, Koji, NARUOKA, Akane, AKIYAMA, Yasuto, KUSUHARA, Masatoshi, MOCHIZUKI, Tohru, YAMAGUCHI, Ken
Published in Biomedical Research (01.01.2018)

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Mutational concordance analysis provides supportive information for double cancer diagnosis

Mutational concordance analysis provides supportive information for double cancer diagnosis

by Hatakeyama, Keiichi, Nagashima, Takeshi, Notsu, Akifumi, Ohshima, Keiichi, Ohnami, Sumiko, Ohnami, Shumpei, Shimoda, Yuji, Naruoka, Akane, Maruyama, Koji, Iizuka, Akira, Ashizawa, Tadashi, Kenmotsu, Hirotsugu, Mochizuki, Tohru, Urakami, Kenichi, Akiyama, Yasuto, Yamaguchi, Ken
Published in BMC cancer (19.02.2021)

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Development of two 410-cancer-gene panel tests for solid tumors and liquid biopsy based on genome data of 5,143 Japanese cancer patients

Development of two 410-cancer-gene panel tests for solid tumors and liquid biopsy based on genome data of 5,143 Japanese cancer patients

by SHIMODA, Yuji, NAGASHIMA, Takeshi, URAKAMI, Kenichi, KAMADA, Fukumi, NAKATANI, Sou, MIZUGUCHI, Maki, SERIZAWA, Masakuni, HATAKEYAMA, Keiichi, OHSHIMA, Keiichi, MOCHIZUKI, Tohru, OHNAMI, Sumiko, OHNAMI, Shumpei, KAWAKAMI, Takeshi, YAMAZAKI, Kentaro, MURAKAMI, Haruyasu, KENMOTSU, Hirotsugu, SHIOMI, Akio, AKIYAMA, Yasuto, YAMAGUCHI, Ken
Published in Biomedical Research (18.08.2022)

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Impact of somatic mutations and transcriptomic alterations on cancer aneuploidy

Impact of somatic mutations and transcriptomic alterations on cancer aneuploidy

by HATAKEYAMA, Keiichi, NAGASHIMA, Takeshi, OHSHIMA, Keiichi, OHNAMI, Sumiko, OHNAMI, Shumpei, SHIMODA, Yuji, NARUOKA, Akane, MARUYAMA, Koji, IIZUKA, Akira, ASHIZAWA, Tadashi, KENMOTSU, Hirotsugu, MOCHIZUKI, Tohru, URAKAMI, Kenichi, AKIYAMA, Yasuto, YAMAGUCHI, Ken
Published in Biomedical Research (27.09.2023)

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Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells

Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells

by Ohshima, Keiichi, Kanto, Kaori, Hatakeyama, Keiichi, Ide, Tomomi, Wakabayashi-Nakao, Kanako, Watanabe, Yuko, Sakura, Naoki, Terashima, Masanori, Yamaguchi, Ken, Mochizuki, Tohru
Published in Proteomics (Weinheim) (01.10.2014)

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Implementation of individualized medicine for cancer patients by multiomics-based analyses—the Project HOPE

Implementation of individualized medicine for cancer patients by multiomics-based analyses—the Project HOPE

by YAMAGUCHI, Ken, URAKAMI, Kenichi, OHSHIMA, Keiichi, MOCHIZUKI, Tohru, AKIYAMA, Yasuto, UESAKA, Katsuhiko, NAKAJIMA, Takashi, TAKAHASHI, Mitsuru, TAMAI, Sunao, KUSUHARA, Masatoshi
Published in Biomedical Research (2014)

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Next generation sequencing approach for detecting 491 fusion genes from human cancer

Next generation sequencing approach for detecting 491 fusion genes from human cancer

by URAKAMI, Kenichi, SHIMODA, Yuji, OHSHIMA, Keiichi, NAGASHIMA, Takeshi, SERIZAWA, Masakuni, TANABE, Tomoe, SAITO, Junko, USUI, Tamiko, WATANABE, Yuko, NARUOKA, Akane, OHNAMI, Sumiko, OHNAMI, Shumpei, MOCHIZUKI, Tohru, KUSUHARA, Masatoshi, YAMAGUCHI, Ken
Published in Biomedical Research (01.01.2016)

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Integrated next-generation sequencing analysis of whole exome and 409 cancer-related genes

Integrated next-generation sequencing analysis of whole exome and 409 cancer-related genes

by SHIMODA, Yuji, NAGASHIMA, Takeshi, URAKAMI, Kenichi, TANABE, Tomoe, SAITO, Junko, NARUOKA, Akane, SERIZAWA, Masakuni, MOCHIZUKI, Tohru, OHSHIMA, Keiichi, OHNAMI, Sumiko, OHNAMI, Shumpei, KUSUHARA, Masatoshi, YAMAGUCHI, Ken
Published in Biomedical Research (01.01.2016)

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Pro-gastrin-releasing peptide as a marker for the Ewing sarcoma family of tumors

Pro-gastrin-releasing peptide as a marker for the Ewing sarcoma family of tumors

by Honda, Yosuke, Katagiri, Hirohisa, Takahashi, Mitsuru, Murata, Hideki, Wasa, Junji, Hosaka, Seiichi, Ishida, Yuji, Ito, Ichiro, Muramatsu, Koji, Mochizuki, Tohru, Matsuyama, Yukihiro, Yamaguchi, Ken
Published in International journal of clinical oncology (01.11.2019)

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Optimizing an ion semiconductor sequencing data analysis method to identify somatic mutations in the genomes of cancer cells in clinical tissue samples

Optimizing an ion semiconductor sequencing data analysis method to identify somatic mutations in the genomes of cancer cells in clinical tissue samples

by NAGASHIMA, Takeshi, SHIMODA, Yuji, TANABE, Tomoe, NARUOKA, Akane, SAITO, Junko, SERIZAWA, Masakuni, OHSHIMA, Keiichi, URAKAMI, Kenichi, OHNAMI, Sumiko, OHNAMI, Shumpei, MOCHIZUKI, Tohru, KUSUHARA, Masatoshi, YAMAGUCHI, Ken
Published in Biomedical Research (01.01.2016)

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A novel splice variant of XIAP-associated factor 1 (XAF1) is expressed in peripheral blood containing gastric cancer-derived circulating tumor cells

A novel splice variant of XIAP-associated factor 1 (XAF1) is expressed in peripheral blood containing gastric cancer-derived circulating tumor cells

by Hatakeyama, Keiichi, Yamakawa, Yushi, Fukuda, Yorikane, Ohshima, Keiichi, Wakabayashi-Nakao, Kanako, Sakura, Naoki, Tanizawa, Yutaka, Kinugasa, Yusuke, Yamaguchi, Ken, Terashima, Masanori, Mochizuki, Tohru
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01.10.2015)

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Identification of a novel protein isoform derived from cancer-related splicing variants using combined analysis of transcriptome and proteome

Identification of a novel protein isoform derived from cancer-related splicing variants using combined analysis of transcriptome and proteome

by Hatakeyama, Keiichi, Ohshima, Keiichi, Fukuda, Yorikane, Ogura, Shun-ichiro, Terashima, Masanori, Yamaguchi, Ken, Mochizuki, Tohru
Published in Proteomics (Weinheim) (01.06.2011)

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Immune response-associated gene analysis of 1,000 cancer patients using whole-exome sequencing and gene expression profiling—Project HOPE

Immune response-associated gene analysis of 1,000 cancer patients using whole-exome sequencing and gene expression profiling—Project HOPE

by AKIYAMA, Yasuto, KONDOU, Ryota, IIZUKA, Akira, OHSHIMA, Keiichi, URAKAMI, Kenichi, NAGASHIMA, Takeshi, SHIMODA, Yuji, TANABE, Tomoe, OHNAMI, Sumiko, OHNAMI, Shumpei, KUSUHARA, Masatoshi, MOCHIZUKI, Tohru, YAMAGUCHI, Ken
Published in Biomedical Research (01.01.2016)

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