Sofosbuvir and ledipasvir fixed-dose combination with and without ribavirin in treatment-naive and previously treated patients with genotype 1 hepatitis C virus infection (LONESTAR): an open-label, randomised, phase 2 trial
Lawitz, Eric, Prof, Poordad, Fred F, Prof, Pang, Phillip S, MD, Hyland, Robert H, DPhil, Ding, Xiao, PhD, Mo, Hongmei, PhD, Symonds, William T, PharmD, McHutchison, John G, MD, Membreno, Fernando E, MD
Published in The Lancet (British edition) (08.02.2014)
Published in The Lancet (British edition) (08.02.2014)
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Journal Article
Hepatitis C virus drug resistance–associated substitutions: State of the art summary
Lontok, Erik, Harrington, Patrick, Howe, Anita, Kieffer, Tara, Lennerstrand, Johan, Lenz, Oliver, McPhee, Fiona, Mo, Hongmei, Parkin, Neil, Pilot‐Matias, Tami, Miller, Veronica
Published in Hepatology (Baltimore, Md.) (01.11.2015)
Published in Hepatology (Baltimore, Md.) (01.11.2015)
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Journal Article
Infrequent Development of Resistance in Genotype 1–6 Hepatitis C Virus–Infected Subjects Treated With Sofosbuvir in Phase 2 and 3 Clinical Trials
Svarovskaia, Evguenia S., Dvory-Sobol, Hadas, Parkin, Neil, Hebner, Christy, Gontcharova, Viktoria, Martin, Ross, Ouyang, Wen, Han, Bin, Xu, Simin, Ku, Karin, Chiu, Sophia, Gane, Edward, Jacobson, Ira M., Nelson, David R., Lawitz, Eric, Wyles, David L., Bekele, Neby, Brainard, Diana, Symonds, William T., McHutchison, John G., Miller, Michael D., Mo, Hongmei
Published in Clinical infectious diseases (15.12.2014)
Published in Clinical infectious diseases (15.12.2014)
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Journal Article
Ledipasvir and sofosbuvir fixed-dose combination with and without ribavirin for 12 weeks in treatment-naive and previously treated Japanese patients with genotype 1 hepatitis C: an open-label, randomised, phase 3 trial
Mizokami, Masashi, Prof, Yokosuka, Osamu, Prof, Takehara, Tetsuo, Prof, Sakamoto, Naoya, Prof, Korenaga, Masaaki, MD, Mochizuki, Hitoshi, MD, Nakane, Kunio, MD, Enomoto, Hirayuki, MD, Ikeda, Fusao, MD, Yanase, Mikio, MD, Toyoda, Hidenori, MD, Genda, Takuya, MD, Umemura, Takeji, MD, Yatsuhashi, Hiroshi, Prof, Ide, Tatsuya, MD, Toda, Nobuo, MD, Nirei, Kazushige, Ueno, Yoshiyuki, Prof, Nishigaki, Yoichi, MD, Betular, Juan, BS, Gao, Bing, PhD, Ishizaki, Akinobu, BA, Omote, Masa, PhD, Mo, Hongmei, MD, Garrison, Kim, PhD, Pang, Phillip S, MD, Knox, Steven J, BS, Symonds, William T, PharmD, McHutchison, John G, MD, Izumi, Namiki, Prof, Omata, Masao, Prof
Published in The Lancet infectious diseases (01.06.2015)
Published in The Lancet infectious diseases (01.06.2015)
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Journal Article
Clinical Resistance to Velpatasvir (GS-5816), a Novel Pan-Genotypic Inhibitor of the Hepatitis C Virus NS5A Protein
Lawitz, Eric J, Dvory-Sobol, Hadas, Doehle, Brian P, Worth, Angela S, McNally, John, Brainard, Diana M, Link, John O, Miller, Michael D, Mo, Hongmei
Published in Antimicrobial agents and chemotherapy (01.09.2016)
Published in Antimicrobial agents and chemotherapy (01.09.2016)
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Journal Article
A phase 1, randomized, placebo-controlled, 3-day, dose-ranging study of GS-5885, an NS5A inhibitor, in patients with genotype 1 hepatitis C
Lawitz, Eric J, Gruener, Daniel, Hill, John M, Marbury, Thomas, Moorehead, Lisa, Mathias, Anita, Cheng, Guofeng, Link, John O, Wong, Kelly A, Mo, Hongmei, McHutchison, John G, Brainard, Diana M
Published in Journal of hepatology (01.07.2012)
Published in Journal of hepatology (01.07.2012)
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Journal Article
Post-treatment resistance analysis of hepatitis C virus from phase II and III clinical trials of ledipasvir/sofosbuvir
Wyles, David, Dvory-Sobol, Hadas, Svarovskaia, Evguenia S, Doehle, Brian P, Martin, Ross, Afdhal, Nezam H, Kowdley, Kris V, Lawitz, Eric, Brainard, Diana M, Miller, Michael D, Mo, Hongmei, Gane, Edward J
Published in Journal of hepatology (01.04.2017)
Published in Journal of hepatology (01.04.2017)
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Journal Article
Sofosbuvir in combination with peginterferon alfa-2a and ribavirin for non-cirrhotic, treatment-naive patients with genotypes 1, 2, and 3 hepatitis C infection: a randomised, double-blind, phase 2 trial
Lawitz, Eric, Prof, Lalezari, Jay P, MD, Hassanein, Tarek, Prof, Kowdley, Kris V, Prof, Poordad, Fred F, Prof, Sheikh, Aasim M, MBBS, Afdhal, Nezam H, Prof, Bernstein, David E, Prof, DeJesus, Edwin, MD, Freilich, Bradley, MD, Nelson, David R, Prof, Dieterich, Douglas T, Prof, Jacobson, Ira M, Prof, Jensen, Donald, Prof, Abrams, Gary A, MD, Darling, Jama M, MD, Rodriguez-Torres, Maribel, MD, Reddy, K Rajender, Prof, Sulkowski, Mark S, Prof, Bzowej, Natalie H, MD, Hyland, Robert H, DPhil, Mo, Hongmei, PhD, Lin, Ming, PhD, Mader, Michael, MS, Hindes, Robert, MD, Albanis, Efsevia, MD, Symonds, William T, PharmD, Berrey, Michelle M, MD, Muir, Andrew, Prof
Published in The Lancet infectious diseases (01.05.2013)
Published in The Lancet infectious diseases (01.05.2013)
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Journal Article
Ledipasvir-sofosbuvir in patients with hepatitis C virus genotype 5 infection: an open-label, multicentre, single-arm, phase 2 study
Abergel, Armand, Prof, Asselah, Tarik, Prof, Metivier, Sophie, MD, Kersey, Kathryn, MSc, Jiang, Deyuan, PhD, Mo, Hongmei, MD, Pang, Phillip S, MD, Samuel, Didier, MD, Loustaud-Ratti, Véronique, Prof
Published in The Lancet infectious diseases (01.04.2016)
Published in The Lancet infectious diseases (01.04.2016)
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Journal Article
L159F and V321A Sofosbuvir-Associated Hepatitis C Virus NS5B Substitutions
Svarovskaia, Evguenia S., Gane, Edward, Dvory-Sobol, Hadas, Martin, Ross, Doehle, Brian, Hedskog, Charlotte, Jacobson, Ira M., Nelson, David R., Lawitz, Eric, Brainard, Diana M., McHutchison, John G., Miller, Michael D., Mo, Hongmei
Published in The Journal of infectious diseases (15.04.2016)
Published in The Journal of infectious diseases (15.04.2016)
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Journal Article
Sofosbuvir susceptibility of genotype 1 to 6 HCV from DAA-naïve subjects
Han, Bin, Martin, Ross, Xu, Simin, Parvangada, Aiyappa, Svarovskaia, Evguenia S., Mo, Hongmei, Dvory-Sobol, Hadas
Published in Antiviral research (01.10.2019)
Published in Antiviral research (01.10.2019)
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Journal Article
Characterization of Hepatitis C Virus Resistance from a Multiple-Dose Clinical Trial of the Novel NS5A Inhibitor GS-5885
Wong, Kelly A, Worth, Angela, Martin, Ross, Svarovskaia, Evguenia, Brainard, Diana M, Lawitz, Eric, Miller, Michael D, Mo, Hongmei
Published in Antimicrobial Agents and Chemotherapy (01.12.2013)
Published in Antimicrobial Agents and Chemotherapy (01.12.2013)
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Journal Article
Contribution of a mutational bias in hepatitis C virus replication to the genetic barrier in the development of drug resistance
Powdrill, Megan H, Tchesnokov, Egor P, Kozak, Robert A, Russell, Rodney S, Martin, Ross, Svarovskaia, Evguenia S, Mo, Hongmei, Kouyos, Roger D, Götte, Matthias
Published in Proceedings of the National Academy of Sciences - PNAS (20.12.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (20.12.2011)
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Journal Article
Characterization of hepatitis C virus intergenotypic recombinant strains and associated virological response to sofosbuvir/ribavirin
Hedskog, Charlotte, Doehle, Brian, Chodavarapu, Krishna, Gontcharova, Viktoria, Crespo Garcia, Javier, De Knegt, Robert, Drenth, Joost P.H, McHutchison, John G., Brainard, Diana, Stamm, Luisa M., Miller, Michael D., Svarovskaia, Evguenia, Mo, Hongmei
Published in Hepatology (Baltimore, Md.) (01.02.2015)
Published in Hepatology (Baltimore, Md.) (01.02.2015)
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Journal Article
Adaptation of hepatitis C virus to interferon lambda polymorphism across multiple viral genotypes
Chaturvedi, Nimisha, Svarovskaia, Evguenia S, Mo, Hongmei, Osinusi, Anu O, Brainard, Diana M, Subramanian, G Mani, McHutchison, John G, Zeuzem, Stefan, Fellay, Jacques
Published in eLife (03.09.2019)
Published in eLife (03.09.2019)
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Journal Article
In vitro resistance profile of hepatitis C virus NS5A inhibitor velpatasvir in genotypes 1 to 6
Dvory‐Sobol, Hadas, Han, Bin, Lu, Julia, Yu, Mei, Beran, Rudolf K., Cheng, Guofeng, Martin, Ross, Svarovskaia, Evguenia, Mo, Hongmei
Published in Journal of viral hepatitis (01.08.2019)
Published in Journal of viral hepatitis (01.08.2019)
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Journal Article
Abundant Drug-Resistant NS3 Mutants Detected by Deep Sequencing in Hepatitis C Virus-Infected Patients Undergoing NS3 Protease Inhibitor Monotherapy
Svarovskaia, Evguenia S, Martin, Ross, McHutchison, John G, Miller, Michael D, Mo, Hongmei
Published in Journal of Clinical Microbiology (01.10.2012)
Published in Journal of Clinical Microbiology (01.10.2012)
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Journal Article
Significance of NS5B Substitutions in Genotype 1b Hepatitis C Virus Evaluated by Bioinformatics Analysis
Uchida, Yoshihito, Nakamura, Shugo, Kouyama, Jun-Ichi, Naiki, Kayoko, Motoya, Daisuke, Sugawara, Kayoko, Inao, Mie, Imai, Yukinori, Nakayama, Nobuaki, Tomiya, Tomoaki, Hedskog, Charlotte, Brainard, Diana, Mo, Hongmei, Mochida, Satoshi
Published in Scientific reports (11.06.2018)
Published in Scientific reports (11.06.2018)
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Journal Article
Prevalence of resistance-associated substitutions and phylogenetic analysis of hepatitis C virus infection in Russia
Isakov, Vasily, Hedskog, Charlotte, Wertheim, Joel O., Hostager, Reilly E., Parhy, Bandita, Schneider, Adriano De Bernardi, Suri, Vithika, Mo, Hongmei, Geivandova, Natalia, Morozov, Vyacheslav, Bessonova, Elena, Gankina, Natalya, Zhdanov, Konstantin, Abdurakhmanov, Dzhamal, Svarovskaia, Evguenia
Published in International journal of infectious diseases (01.12.2021)
Published in International journal of infectious diseases (01.12.2021)
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