Thyrotoxic rubber antioxidants, 2-mercaptobenzimidazole and its methyl derivatives, cause both inhibition and induction of drug-metabolizing activity in rat liver microsomes after repeated oral administration
Miyajima, Atsuko, Sakemi-Hoshikawa, Kazue, Usami, Makoto, Mitsunaga, Katsuyoshi, Irie, Tomohiko, Ohno, Yasuo, Sunouchi, Momoko
Published in Biochemical and biophysical research communications (07.10.2017)
Published in Biochemical and biophysical research communications (07.10.2017)
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Journal Article
Effects of lowering the proposed top-concentration limit in an in vitro chromosomal aberration test on assay sensitivity and on the reduction of the number of false positives
Morita, Takeshi, Miyajima, Atsuko, Hatano, Akiko, Honma, Masamitsu
Published in Mutation research. Genetic toxicology and environmental mutagenesis (15.07.2014)
Published in Mutation research. Genetic toxicology and environmental mutagenesis (15.07.2014)
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Journal Article
Potency shift in immunomodulatory activities of zinc oxide (ZnO) nanoparticles in THP-1 cells is associated with cytotoxicity
Miyajima, Atsuko, Kawakami, Tsuyoshi, Komoriya, Kaoru, Kato, Reiko, Usami, Makoto, Isama, Kazuo
Published in Fundamental Toxicological Sciences (2021)
Published in Fundamental Toxicological Sciences (2021)
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Journal Article
Decreased Expression of Cytochromes P450 1A2, 2E1, and 3A4 and Drug Transporters Na+-Taurocholate-Cotransporting Polypeptide, Organic Cation Transporter 1, and Organic Anion-Transporting Peptide-C Correlates with the Progression of Liver Fibrosis in Chronic Hepatitis C Patients
NAKAI, Kenya, TANAKA, Hiromasa, KAMIKAWA, Yuichiro, KUBOTA, Keiichi, KITA, Junji, OZAWA, Shogo, OHNO, Yasuo, HANADA, Kazuhiko, OGATA, Hiroyasu, SUZUKI, Fumitaka, KUMADA, Hiromitsu, MIYAJIMA, Atsuko, ISHIDA, Seiichi, SUNOUCHI, Momoko, HABANO, Wataru
Published in Drug metabolism and disposition (01.09.2008)
Published in Drug metabolism and disposition (01.09.2008)
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Journal Article
In vitro cytotoxicity of the thyrotoxic and hepatotoxic rubber antioxidant 2-mercaptobenzimidazole and its 4- or 5-methyl derivatives in rabbit corneal cells
Kuroda, Yukie, Miyajima, Atsuko, Sakemi-Hoshikawa, Kazue, Usami, Makoto, Mitsunaga, Katsuyoshi, Ohno, Yasuo, Sunouchi, Momoko
Published in Fundamental Toxicological Sciences (2020)
Published in Fundamental Toxicological Sciences (2020)
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Journal Article
Comparative metabolome analysis of cultured fetal and adult hepatocytes in humans
Kim, Su-Ryang, Kubo, Takashi, Kuroda, Yukie, Hojyo, Maki, Matsuo, Takuya, Miyajima, Atsuko, Usami, Makoto, Sekino, Yuko, Matsushita, Taku, Ishida, Seiichi
Published in Journal of toxicological sciences (2014)
Published in Journal of toxicological sciences (2014)
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Journal Article
Inhibitory and inductive effects of 4- or 5-methyl-2-mercaptobenzimidazole, thyrotoxic and hepatotoxic rubber antioxidants, on several forms of cytochrome P450 in primary cultured rat and human hepatocytes
Miyajima, Atsuko, Kuroda, Yukie, Sakemi-Hoshikawa, Kazue, Usami, Makoto, Mitsunaga, Katsuyoshi, Irie, Tomohiko, Ohno, Yasuo, Sunouchi, Momoko
Published in Toxicology reports (01.01.2020)
Published in Toxicology reports (01.01.2020)
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Journal Article
In vitro metabolism of 4-methyl- and 5-methyl-2-mercaptobenzimidazole, thyrotoxic and hepatotoxic rubber antioxidants, in rat liver microsomes
Miyajima, Atsuko, Kuroda, Yukie, Sakemi-Hoshikawa, Kazue, Usami, Makoto, Mitsunaga, Katsuyoshi, Irie, Tomohiko, Ohno, Yasuo, Sunouchi, Momoko
Published in Fundamental Toxicological Sciences (19.06.2018)
Published in Fundamental Toxicological Sciences (19.06.2018)
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Journal Article
Effect of nanoparticles on the cytotoxicity of coexisting metal salts
Isama, Kazuo, Kawakami, Tsuyoshi, Sakai, Keiko, Miyajima, Atsuko, Matsuoka, Atsuko
Published in Toxicology letters (01.06.2012)
Published in Toxicology letters (01.06.2012)
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Journal Article
Effects of 13 developmentally toxic chemicals on the migration of rat cephalic neural crest cells in vitro
Usami, Makoto, Mitsunaga, Katsuyoshi, Miyajima, Atsuko, Takamatu, Mina, Kazama, Shugo, Irie, Tomohiko, Doi, Osamu, Takizawa, Tatsuya
Published in Congenital anomalies (01.03.2016)
Published in Congenital anomalies (01.03.2016)
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Journal Article
Simple in vitro migration assay for neural crest cells and the opposite effects of all-trans-retinoic acid on cephalic- and trunk-derived cells
Usami, Makoto, Mitsunaga, Katsuyoshi, Irie, Tomohiko, Miyajima, Atsuko, Doi, Osamu
Published in Congenital anomalies (01.08.2014)
Published in Congenital anomalies (01.08.2014)
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Journal Article
Proteomic analysis of valproic acid-induced embryotoxicity in cultured post-implantation rat embryos
Usami, Makoto, Takamatsu, Mina, Kazama, Shugo, Mitsunaga, Katsuyoshi, Miyajima, Atsuko, Irie, Tomohiko, Doi, Osamu, Takizawa, Tatsuya, Nagi, Teruko, Sunouchi, Momoko
Published in Fundamental Toxicological Sciences (2017)
Published in Fundamental Toxicological Sciences (2017)
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Journal Article
Global gene expression changes including drug metabolism and disposition induced by three-dimensional culture of HepG2 cells-Involvement of microtubules
Horiuchi, Shin-ichiro, Ishida, Seiichi, Hongo, Tomokatsu, Ishikawa, Youichi, Miyajima, Atsuko, Sawada, Jun-ichi, Ohno, Yasuo, Nakazawa, Ken, Ozawa, Shogo
Published in Biochemical and biophysical research communications (16.01.2009)
Published in Biochemical and biophysical research communications (16.01.2009)
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Journal Article
Sexing of postimplantation rat embryos in stored two-dimensional electrophoresis (2-DE) samples by polymerase chain reaction (PCR) of an Sry sequence
Miyajima, Atsuko, Sunouchi, Momoko, Mitsunaga, Katsuyoshi, Yamakoshi, Yoko, Nakazawa, Ken, Usami, Makoto
Published in Journal of toxicological sciences (01.12.2009)
Published in Journal of toxicological sciences (01.12.2009)
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Journal Article
Sequence-based Analysis of the CYP2D636-CYP2D610 Tandem-type Arrangement, a Major CYP2D610 Haplotype in the Japanese Population
Soyama, Akiko, Saito, Yoshiro, Kubo, Takashi, Miyajima, Atsuko, Ohno, Yasuo, Komamura, Kazuo, Ueno, Kazuyuki, Kamakura, Shiro, Kitakaze, Masafumi, Tomoike, Hitonobu, Ozawa, Shogo, Sawada, Jun-ichi
Published in DRUG METABOLISM AND PHARMACOKINETICS (2006)
Published in DRUG METABOLISM AND PHARMACOKINETICS (2006)
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Journal Article
プラスチック製医療機器の力学特性に対する薬剤の影響評価
迫田, 秀行, 相澤, 雅美, 上田, 麻子, 戸井田, 瞳, 植松, 美幸, 中岡, 竜介, 宮島, 敦子, 蓜島, 由二
Published in YAKUGAKU ZASSHI (01.02.2021)
Published in YAKUGAKU ZASSHI (01.02.2021)
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Journal Article
Novel Nonsynonymous Single Nucleotide Polymorphisms in the CYP2D6 Gene
Soyama, Akiko, Kubo, Takashi, Shiseki, Kisho, Miyajima, Atsuko, Saito, Yoshiro, Komamura, Kazuo, Ueno, Kazuyuki, Kamakura, Shiro, Kitakaze, Masafumi, Tomoike, Hitonobu, Ozawa, Shogo, Sawada, Jun-ichi
Published in Drug metabolism and pharmacokinetics (2004)
Published in Drug metabolism and pharmacokinetics (2004)
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Journal Article