Utility of imaging mass spectrometry (IMS) by matrix-assisted laser desorption ionization (MALDI) on an ion trap mass spectrometer in the analysis of drugs and metabolites in biological tissues
Drexler, Dieter M., Garrett, Timothy J., Cantone, Joseph L., Diters, Richard W., Mitroka, James G., Prieto Conaway, Maria C., Adams, Stephen P., Yost, Richard A., Sanders, Mark
Published in Journal of pharmacological and toxicological methods (01.05.2007)
Published in Journal of pharmacological and toxicological methods (01.05.2007)
Get full text
Journal Article
CYTOCHROME P450 3A-MEDIATED METABOLISM OF BUSPIRONE IN HUMAN LIVER MICROSOMES
Zhu, Mingshe, Zhao, Weiping, Jimenez, Humberto, Zhang, Donglu, Yeola, Suresh, Dai, Renke, Vachharajani, Nimish, Mitroka, James
Published in Drug metabolism and disposition (01.04.2005)
Published in Drug metabolism and disposition (01.04.2005)
Get full text
Journal Article
Analysis of low level radioactive metabolites in biological fluids using high-performance liquid chromatography with microplate scintillation counting: Method validation and application
Zhu, Mingshe, Zhao, Weiping, Vazquez, Natasha, Mitroka, James G.
Published in Journal of pharmaceutical and biomedical analysis (01.09.2005)
Published in Journal of pharmaceutical and biomedical analysis (01.09.2005)
Get full text
Journal Article
Comparative Metabolism of Radiolabeled Muraglitazar in Animals and Humans by Quantitative and Qualitative Metabolite Profiling
DONGLU ZHANG, LIFEI WANG, YEOLA, Suresh, MITROKA, James, HARIHARAN, Narayanan, HOSAGRAHARA, Vinayak, CHANDRASENA, Gamini, WEN CHYI SHYU, HUMPHREYS, W. Griffith, RAGHAVAN, Nirmala, HAIYING ZHANG, WENYING LI, CHENG, Peter T, MING YAO, LITAO ZHANG, MINGSHE ZHU, BONACORSI, Samuel
Published in Drug metabolism and disposition (01.01.2007)
Published in Drug metabolism and disposition (01.01.2007)
Get full text
Journal Article
METABOLISM, PHARMACOKINETICS, AND PROTEIN COVALENT BINDING OF RADIOLABELED MAXIPOST (BMS-204352) IN HUMANS
ZHANG, Donglu, KRISHNA, Rajesh, WANG, Lifei, ZENG, Jianing, MITROKA, James, DAI, Renke, NARASIMHAN, Narayanan, REEVES, Richard A, SRINIVAS, Nuggehally R, KLUNK, Lewis J
Published in Drug metabolism and disposition (01.01.2005)
Published in Drug metabolism and disposition (01.01.2005)
Get full text
Journal Article
Comparative Metabolism of 14C-Labeled Apixaban in Mice, Rats, Rabbits, Dogs, and Humans
Zhang, Donglu, He, Kan, Raghavan, Nirmala, Wang, Lifei, Mitroka, James, Maxwell, Brad D, Knabb, Robert M, Frost, Charles, Schuster, Alan, Hao, Feng, Gu, Zheming, Humphreys, W Griffith, Grossman, Scott J
Published in Drug metabolism and disposition (01.08.2009)
Published in Drug metabolism and disposition (01.08.2009)
Get full text
Journal Article
AMIDE N-GLUCURONIDATION OF MAXIPOST CATALYZED BY UDP-GLUCURONOSYLTRANSFERASE 2B7 IN HUMANS
DONGLU ZHANG, WEIPING ZHAO, ROONGTA, Vikram A, MITROKA, James G, KLUNK, Lewis J, MINGSHE ZHU
Published in Drug metabolism and disposition (01.05.2004)
Published in Drug metabolism and disposition (01.05.2004)
Get full text
Journal Article
METABOLISM OF [14C]GEMOPATRILAT AFTER ORAL ADMINISTRATION TO RATS, DOGS, AND HUMANS
WAIT, Jill C. M, VACCHARAJANI, Nimish, MITROKA, James, JEMAL, Mohammed, KHAN, Sanaullah, BONACORSI, Samuel J, KENT RINEHART, J, IYER, Ramaswamy A
Published in Drug metabolism and disposition (01.06.2006)
Published in Drug metabolism and disposition (01.06.2006)
Get full text
Journal Article
PROTEIN COVALENT BINDING OF MAXIPOST THROUGH A CYTOCHROME P450-MEDIATED ORTHO-QUINONE METHIDE INTERMEDIATE IN RATS
DONGLU ZHANG, OGAN, Marc, GEDAMKE, Richard, ROONGTA, Vikram, DAI, Renke, MINGSHE ZHU, RINEHART, J. Kent, KLUNK, Lewis, MITROKA, James
Published in Drug metabolism and disposition (01.07.2003)
Published in Drug metabolism and disposition (01.07.2003)
Get full text
Journal Article
In vitro and in vivo metabolism of a gamma-secretase inhibitor BMS-299897 and generation of active metabolites in milligram quantities with a microbial bioreactor
Zhang, Donglu, Hanson, Ronald, Roongta, Vikram, Dischino, Douglas D, Gao, Qi, Sloan, Charles P, Polson, Craig, Keavy, Daniel, Zheng, Ming, Mitroka, James, Yeola, Suresh
Published in Current drug metabolism (01.12.2006)
Published in Current drug metabolism (01.12.2006)
Get more information
Journal Article
Subchronic Urinary Bladder Effects of Muraglitazar in Male Rats1
Van Vleet, Terry R., White, M. Randy, Sanderson, Thomas P., Cohen, Samuel M., Cano, Martin, Arnold, Lora L., Waites, C. Robbie, Schilling, Beth E., Mitroka, James, Dominick, Mark A.
Published in Toxicological sciences (01.03.2007)
Published in Toxicological sciences (01.03.2007)
Get full text
Journal Article
Comparative Biotransformation of Radiolabeled [14C]Omapatrilat and Stable-labeled [13C2]Omapatrilat after Oral Administration to Rats, Dogs, and Humans
Ramaswamy A. Iyer, Bimal Malhotra, Sanaullah Khan, James Mitroka, Samuel Bonacorsi, Jr, Stephen C. Waller, J. Kent Rinehart, Kishin Kripalani
Published in Drug metabolism and disposition (01.01.2003)
Published in Drug metabolism and disposition (01.01.2003)
Get full text
Journal Article
Metabolism of [14C]Omapatrilat, a Sulfhydryl-Containing Vasopeptidase Inhibitor in Humans
Ramaswamy A. Iyer, James Mitroka, Bimal Malhotra, Samuel Bonacorsi, Jr, Stephen C. Waller, J. Kent Rinehart, Vikram A. Roongta, Kishin Kripalani
Published in Drug metabolism and disposition (01.01.2001)
Get full text
Published in Drug metabolism and disposition (01.01.2001)
Journal Article
Oral bioavailability and disposition of [14C]omapatrilat in healthy subjects
Malhotra, B K, Iyer, R A, Soucek, K M, Behr, D, Liao, W C, Mitroka, J G, Kaul, S, Cohen, M B, Knupp, C A
Published in Journal of clinical pharmacology (01.08.2001)
Published in Journal of clinical pharmacology (01.08.2001)
Get more information
Journal Article
Comparative Metabolism of 14 C-Labeled Apixaban in Mice, Rats, Rabbits, Dogs, and Humans
Zhang, Donglu, He, Kan, Raghavan, Nirmala, Wang, Lifei, Mitroka, James, Maxwell, Brad D., Knabb, Robert M., Frost, Charles, Schuster, Alan, Hao, Feng, Gu, Zheming, Humphreys, W. Griffith, Grossman, Scott J.
Published in Drug metabolism and disposition (01.08.2009)
Published in Drug metabolism and disposition (01.08.2009)
Get full text
Journal Article
Subchronic Urinary Bladder Effects of Muraglitazar in Male Rats
Van Vleet, Terry R., White, M. Randy, Sanderson, Thomas P., Cohen, Samuel M., Cano, Martin, Arnold, Lora L., Waites, C. Robbie, Schilling, Beth E., Mitroka, James, Dominick, Mark A.
Published in Toxicological sciences (01.03.2007)
Published in Toxicological sciences (01.03.2007)
Get full text
Journal Article
Comparative Metabolism of 14C-Labeled Apixaban in Mice, Rats, Rabbits, Dogs, and HumansS
DONGLU ZHANG, KAN HE, ZHEMING GU, HUMPHREYS, W. Griffith, GROSSMAN, Scott J, RAGHAVAN, Nirmala, LIFEI WANG, MITROKA, James, MAXWELL, Brad D, KNABB, Robert M, FROST, Charles, SCHUSTER, Alan, FENG HAO
Published in Drug metabolism and disposition (2009)
Get full text
Published in Drug metabolism and disposition (2009)
Journal Article