Preparation and biological evaluation of 1′-cyano-2′-C-methyl pyrimidine nucleosides as HCV NS5B polymerase inhibitors
Mish, Michael R., Cho, Aesop, Kirschberg, Thorsten, Xu, Jie, Sebastian Zonte, C., Fenaux, Martijn, Park, Yeojin, Babusis, Darius, Feng, Joy Y., Ray, Adrian S., Kim, Choung U.
Published in Bioorganic & medicinal chemistry letters (15.07.2014)
Published in Bioorganic & medicinal chemistry letters (15.07.2014)
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Discovery of a 2′-fluoro-2′-C-methyl C-nucleotide HCV polymerase inhibitor and a phosphoramidate prodrug with favorable properties
Kirschberg, Thorsten A., Metobo, Sammy, Clarke, Michael O., Aktoudianakis, Vangelis, Babusis, Darius, Barauskas, Ona, Birkus, Gabriel, Butler, Thomas, Byun, Daniel, Chin, Gregory, Doerffler, Edward, Edwards, Thomas E., Fenaux, Martijn, Lee, Rick, Lew, Willard, Mish, Michael R., Murakami, Eisuke, Park, Yeojin, Squires, Neil H., Tirunagari, Neeraj, Wang, Ting, Whitcomb, Mark, Xu, Jie, Yang, Huiling, Ye, Hong, Zhang, Lijun, Appleby, Todd C., Feng, Joy Y., Ray, Adrian S., Cho, Aesop, Kim, Choung U.
Published in Bioorganic & medicinal chemistry letters (15.04.2017)
Published in Bioorganic & medicinal chemistry letters (15.04.2017)
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Journal Article
Synthesis and characterization of 1′-C-cyano-2′-fluoro-2′-C-methyl pyrimidine nucleosides as HCV polymerase inhibitors
Kirschberg, Thorsten A., Mish, Michael R., Zhang, Lijun, Squires, Neil H., Wang, Ke-Yu, Cho, Aesop, Feng, Joy Y., Fenaux, Martijn, Babusis, Darius, Park, Yeojin, Ray, Adrian S., Kim, Choung U.
Published in Bioorganic & medicinal chemistry letters (01.03.2015)
Published in Bioorganic & medicinal chemistry letters (01.03.2015)
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Journal Article
CD73 화합물
CHIN GREGORY F, GOYAL BINDU, MISH MICHAEL R, ENSAN DEEBA, COSMAN ELLIS JENNIFER L, TAMSHEN KYLE C, HO STEPHEN, MACKMAN RICHARD L, SIEGEL DUSTIN S, CLARKE MICHAEL O, YANG HAI, BARTLETT MARK J
Year of Publication 27.06.2024
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Year of Publication 27.06.2024
Patent
TOLL LIKE RECEPTOR MODULATOR COMPOUNDS
ZABLOCKI JEFF, CHIN GREGORY, PYUN HYUNG JUNG, METOBO SAMUEL E, MISH MICHAEL R, MACKMAN RICHARD L, AKTOUDIANAKIS EVANGELOS
Year of Publication 14.12.2021
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Year of Publication 14.12.2021
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항바이러스 화합물
CHIN GREGORY F, GOYAL BINDU, MISH MICHAEL R, JANSA PETR, MACKMAN RICHARD L, SIEGEL DUSTIN S, CLARKE MICHAEL O, BYUN DANIEL H
Year of Publication 24.10.2022
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Year of Publication 24.10.2022
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PROCESSES FOR PREPARING TOLL-LIKE RECEPTOR MODULATOR COMPOUNDS
MERIT JEFFREY E, WANG XIANGHONG, CHIN GREGORY F, LATHROP STEPHEN P, ZHENG ZEHUA, ASSELIN SYLVIE M, WENDERSKI TODD A, VIEIRA TIAGO, LEW WILLARD, AMBROSI ANDREA, PYUN HYUNG JUNG, BACHRACH FLORENCE J, METOBO SAMUEL E, MISH MICHAEL R, WEINSTEIN ADAM B, BADALOV PAVEL R, MACKMAN RICHARD L, REGENS CHRISTOPHER S, PRITCHETT BEAU P, AKTOUDIANAKIS EVANGELOS
Year of Publication 21.06.2024
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Year of Publication 21.06.2024
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POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE
DESAI MANOJ C, TREJO MARTIN TERESA ALEJANDRA, BACON ELIZABETH M, COTTELL JEROMY J, CAI ZHENHONG R, TAYLOR JAMES G, LAZERWITH SCOTT E, JI MINGZHE, PYUN HYUNG JUNG, JIN HAOLUN, MISH MICHAEL R, CHEN XIAOWU, MORGANELLI PHILIP ANTHONY
Year of Publication 08.05.2023
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Year of Publication 08.05.2023
Patent
항바이러스 화합물
CHIN GREGORY F, GOYAL BINDU, SIEGEL DUSTIN S, SPERANDIO DAVID, MISH MICHAEL R, ZHANG LIJUN, HUI HON C, JANSA PETR, MACKMAN RICHARD L, CLARKE MICHAEL O, YANG HAI, CHUN BYOUNG KWON, BYUN DANIEL H
Year of Publication 20.10.2022
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Year of Publication 20.10.2022
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POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE
DESAI MANOJ C, TREJO MARTIN TERESA ALEJANDRA, BACON ELIZABETH M, COTTELL JEROMY J, CAI ZHENHONG R, TAYLOR JAMES G, LAZERWITH SCOTT E, JI MINGZHE, PYUN HYUNG JUNG, JIN HAOLUN, MISH MICHAEL R, CHEN XIAOWU, MORGANELLI PHILIP ANTHONY
Year of Publication 14.06.2022
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Year of Publication 14.06.2022
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CD73를 억제하는 2,4-다이옥소피리미딘 화합물
CHIN GREGORY F, GOYAL BINDU, TANG DORIS T, ENSAN DEEBA, SCHROEDER SCOTT D, SIEGEL DUSTIN S, COSMAN JENNIFER L, MISH MICHAEL R, HO STEPHEN, HUI HON C, MACKMAN RICHARD L, CLARKE MICHAEL O, YANG HAI, BARTLETT MARK J, SHAPIRO NATHAN D
Year of Publication 11.01.2023
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Year of Publication 11.01.2023
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POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE
DESAI MANOJ C, TREJO MARTIN TERESA ALEJANDRA, BACON ELIZABETH M, COTTELL JEROMY J, CAI ZHENHONG R, TAYLOR JAMES G, LAZERWITH SCOTT E, JI MINGZHE, PYUN HYUNG JUNG, JIN HAOLUN, MISH MICHAEL R, CHEN XIAOWU, MORGANELLI PHILIP ANTHONY
Year of Publication 28.01.2022
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Year of Publication 28.01.2022
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POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE
DESAI MANOJ C, TREJO MARTIN TERESA ALEJANDRA, BACON ELIZABETH M, COTTELL JEROMY J, CAI ZHENHONG R, TAYLOR JAMES G, LAZERWITH SCOTT E, JI MINGZHE, PYUN HYUNG JUNG, JIN HAOLUN, MISH MICHAEL R, CHEN XIAOWU, MORGANELLI PHILIP ANTHONY
Year of Publication 06.05.2021
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Year of Publication 06.05.2021
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톨-유사 수용체 조절제 화합물의 제조 방법
MERIT JEFFREY E, WANG XIANGHONG, CHIN GREGORY F, LATHROP STEPHEN P, ZHENG ZEHUA, ASSELIN SYLVIE M, WENDERSKI TODD A, VIEIRA TIAGO, LEW WILLARD, AMBROSI ANDREA, PYUN HYUNG JUNG, BACHRACH FLORENCE J, METOBO SAMUEL E, MISH MICHAEL R, WEINSTEIN ADAM B, BADALOV PAVEL R, MACKMAN RICHARD L, REGENS CHRISTOPHER S, PRITCHETT BEAU P, AKTOUDIANAKIS EVANGELOS
Year of Publication 28.03.2022
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Year of Publication 28.03.2022
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POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE
DESAI MANOJ C, TREJO MARTIN TERESA ALEJANDRA, BACON ELIZABETH M, COTTELL JEROMY J, CAI ZHENHONG R, TAYLOR JAMES G, LAZERWITH SCOTT E, JI MINGZHE, PYUN HYUNG JUNG, JIN HAOLUN, MISH MICHAEL R, CHEN XIAOWU, MORGANELLI PHILIP ANTHONY
Year of Publication 12.06.2020
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Year of Publication 12.06.2020
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POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE
DESAI MANOJ C, TREJO MARTIN TERESA ALEJANDRA, BACON ELIZABETH M, COTTELL JEROMY J, CAI ZHENHONG R, TAYLOR JAMES G, LAZERWITH SCOTT E, JI MINGZHE, PYUN HYUNG JUNG, JIN HAOLUN, MISH MICHAEL R, CHEN XIAOWU, MORGANELLI PHILIP ANTHONY
Year of Publication 05.11.2019
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Year of Publication 05.11.2019
Patent
TOLL LIKE RECEPTOR MODULATOR COMPOUNDS
ZABLOCKI JEFF, CHIN GREGORY, PYUN HYUNG JUNG, METOBO SAMUEL E, MISH MICHAEL R, MACKMAN RICHARD L, AKTOUDIANAKIS EVANGELOS
Year of Publication 13.10.2017
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Year of Publication 13.10.2017
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TOLL LIKE RECEPTOR MODULATOR COMPOUNDS
ZABLOCKI JEFF, CHIN GREGORY, PYUN HYUNG JUNG, METOBO SAMUEL E, MISH MICHAEL R, MACKMAN RICHARD L, AKTOUDIANAKIS EVANGELOS
Year of Publication 28.09.2016
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Year of Publication 28.09.2016
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