SOLID FORMS OF A MACROCYCLIC COMPOUNDS AS CFTR MODULATORS AND THEIR PREPARATION
PERESYPKIN, Andrey, MEDEK, Ales, GAGNON, Kevin, ROEPER, Stefanie, BAEK, Minson, SIESEL, David A, SHI, Yi, SHRESTHA, Muna
Year of Publication 07.11.2024
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Year of Publication 07.11.2024
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SOLID FORMS OF A MACROCYCLIC COMPOUNDS AS CFTR MODULATORS AND THEIR PREPARATION
PERESYPKIN, Andrey, MEDEK, Ales, GAGNON, Kevin, ROEPER, Stefanie, BAEK, Minson, SIESEL, David A, SHRESTHA, Muna
Year of Publication 23.11.2023
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Year of Publication 23.11.2023
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Methods of preparing and crystalline forms of (6a,12a)-17-amino-12-methyl-6,15-bis(trifluoromethyl)-13,19-dioxa-3,4,18-triazatricyclo[ 12.3.1.12,5]nonadeca-1(18),2,4,14,16-pentaen-6-ol
BAEK Minson, GAGNON Kevin, ROEPER Stefanie, SIESEL David A, ANGELL Paul Timothy, PERESYPKIN Andrey, MEDEK Ales, ZHOU Jinglan, SHI Yi, MACK Daniel James, SHRESTHA Muna
Year of Publication 01.10.2024
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Year of Publication 01.10.2024
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METHODS OF PREPARING AND CRYSTALLINE FORMS OF (6A,12A)-17-AMINO-12-METHYL-6,15-BIS(TRIFLUOROMETHYL)-13,19-DIOXA-3,4,18-TRIAZATRICYCLO[ 12.3.1.12,5]NONADECA-1(18),2,4,14,16-PENTAEN-6-OL
ZHOU, Jinglan, PERESYPKIN, Andrey, MEDEK, Ales, GAGNON, Kevin, ANGELL, Paul Timothy, ROEPER, Stefanie, BAEK, Minson, MACK, Daniel James, SIESEL, David A, SHI, Yi, SHRESTHA, Muna
Year of Publication 22.08.2024
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Year of Publication 22.08.2024
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METHODS OF PREPARING AND CRYSTALLINE FORMS OF (6A,12A)-17-AMINO-12-METHYL-6,15-BIS(TRIFLUOROMETHYL)-13,19-DIOXA-3,4,18-TRIAZATRICYCLO[ 12.3.1.12,5]NONADECA-1(18),2,4,14,16-PENTAEN-6-OL
ZHOU, Jinglan, PERESYPKIN, Andrey, MEDEK, Ales, GAGNON, Kevin, ANGELL, Paul Timothy, ROEPER, Stefanie, BAEK, Minson, MACK, Daniel James, SIESEL, David A, SHRESTHA, Muna
Year of Publication 10.08.2023
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Year of Publication 10.08.2023
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MACROCYCLES CONTAINING A 1,3,4-OXADIAZOLE RING FOR USE AS MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR
ZHOU, Jinglan, RAMTOHUL, Yeeman K, LATERREUR, Julie, COON, Timothy, REDDY, Thumkunta Jagadeeswar, HADIDA RUAH, Sara Sabina, PARASELLI, Prasuna, MILLER, Mark Thomas, CLEVELAND, Thomas, GALLANT, Michel, STURINO, Claudio, BOOKSER, Brett C, GROOTENHUIS, Peter Diederik Jan, BAEK, Minson, VALDEZ, Lino, BECHARA, William Schulz, CLEMENS, Jeremy J
Year of Publication 27.09.2023
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Year of Publication 27.09.2023
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MODULATOR OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR, PHARMACEUTICAL COMPOSITIONS, METHODS OF TREATMENT, AND PROCESS FOR MAKING THE MODULATOR
HADIDA RUAH, SARA SABINA, JOSHI, PRAMOD VIRUPAX, ALCACIO, TIMOTHY, KHATUYA, HARIPADA, MCAULEY-AOKI, RACHEL, ZHOU, JINGLAN, MCCARTNEY, JASON, SIESEL, DAVID ANDREW, HUGHES, ROBERT M, PARASELLI, PRASUNA, CLEVELAND, THOMAS, TERMIN, ANDREAS P, PIERRE, FABRICE JEAN DENIS, FRIEMAN, BRYAN A, KESHAVARZ-SHOKRI, ALI, ABELA, ALEXANDER RUSSELL, BAEK, MINSON, ANDERSON, COREY, KRENITSKY, PAUL JOHN, BUSCH, BRETT BRADLEY, ZHANG, BEILI, MELILLO, VITO, GROOTENHUIS, PETER, VAN GOOR, FREDRICK, UY, JOHNNY, MILLER, MARK THOMAS
Year of Publication 05.03.2024
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Year of Publication 05.03.2024
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MODULATOR OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR, PHARMACEUTICAL COMPOSITIONS, METHODS OF TREATMENT, AND PROCESS FOR MAKING THE MODULATOR
GROSS, Raymond, Stanley, ABELA, Alexander, Russell, MCCARTNEY, Jason, CLEVELAND, Thomas, KANG, Ping, KESHAVARZ-SHOKRI, Ali, JOSHI, Pramod, Virupax, STAVROPOULOS, Kathy, ALCACIO, Timothy, KHATUYA, KHATUYA, Haripada, TERMIN, Andreas, P, BAEK, Minson, SHI, Yi, SHRESTHA, Muna, FERRIS,, Lori, Ann, GROOTENHUIS, Peter Diederik, Jan, HSIA, Clara, Kuang-Ju, KRENITSKY, Paul, John, ANGELL, Paul, Timothy, MILLER, Mark, Thomas, ANDERSON, Corey, PARASELLI, Prasuna, YOUNG, Tomothy, John, ZHOU,, Jinglan, GULEVICH, Anton, VAN GOOR, Fredrik, F, UY, Johnny, CLEMENS, Jeremy, J, HADIDA RUAH, Sara, Sabina, PIERRE, Fa brice Jean, Denis, SIESEL, David, Andrew, HUGHES, Robert, M
Year of Publication 25.06.2024
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Year of Publication 25.06.2024
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MACROCYCLES CONTAINING A 1,3,4-OXADIAZOLE RING FOR USE AS MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR
ZHOU, Jinglan, RAMTOHUL, Yeeman K, LATERREUR, Julie, COON, Timothy, REDDY, Thumkunta Jagadeeswar, HADIDA RUAH, Sara Sabina, PARASELLI, Prasuna, MILLER, Mark Thomas, CLEVELAND, Thomas, GALLANT, Michel, STURINO, Claudio, BOOKSER, Brett C, GROOTENHUIS, Peter Diederik Jan, BAEK, Minson, VALDEZ, Lino, BECHARA, William Schulz, CLEMENS, Jeremy J
Year of Publication 22.06.2023
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Year of Publication 22.06.2023
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MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR
ZHOU, Jinglan, RAMTOHUL, Yeeman K, LATERREUR, Julie, REDDY, Thumkunta Jagadeeswar, HADIDA RUAH, Sara Sabina, PARASELLI, Prasuna, MILLER, Mark Thomas, CLEVELAND, Thomas, COON, Timothy R, GROOTENHUIS, Peter, GALLANT, Michel, STURINO, Claudio, BOOKSER, Brett C, MELILLO, Vito, BAEK, Minson, VALDEZ, Lino, BECHARA, William Schulz, CLEMENS, Jeremy J
Year of Publication 14.06.2023
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Year of Publication 14.06.2023
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Modulator of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator
Hsia, Clara, Mccartney, Jason, Ferris, Lori, Cleveland, Thomas, Young, Timothy, Uy, Johnny, Gulevich, Anton, Termin, Andreas P, Abela, Alexander Russell, Krenitsky, Paul John, Alcacio, Timothy, Pierre, Fabrice Jean Denis, Stavropoulos, Kathy, Grootenhuis, Peter Diederik, Shi, Yi, Khatuya, Haripada, Hughes, Robert M, Gross, Raymond, Hadida Ruah, Sara Sabina, Angell, Paul, Clemens, Jeremy, Kang, Ping, Siesel, David Andrew, Baek, Minson, Joshi, Pramod Virupax, Paraselli, Prasuna, Zhou, Jinglan, Van Goor, Fredrick, Miller, Mark Thomas, Shrestha, Muna, Anderson, Corey, Keshavarz-Shokri, Ali
Year of Publication 24.11.2023
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Year of Publication 24.11.2023
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Modulators of cystic fibrosis transmembrane conductance regulator
ZHOU, Jinglan, RAMTOHUL, Yeeman K, LATERREUR, Julie, REDDY, Thumkunta Jagadeeswar, HADIDA RUAH, Sara Sabina, PARASELLI, Prasuna, MILLER, Mark Thomas, CLEVELAND, Thomas, COON, Timothy R, GROOTENHUIS, Peter, GALLANT, Michel, STURINO, Claudio, BOOKSER, Brett C, MELILLO, Vito, BAEK, Minson, VALDEZ, Lino, BECHARA, William Schulz, CLEMENS, Jeremy J
Year of Publication 13.04.2023
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Year of Publication 13.04.2023
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Modulators of cystic fibrosis transmembrane conductance regulator
ZHOU, Jinglan, RAMTOHUL, Yeeman K, LATERREUR, Julie, REDDY, Thumkunta Jagadeeswar, HADIDA RUAH, Sara Sabina, PARASELLI, Prasuna, MILLER, Mark Thomas, CLEVELAND, Thomas, COON, Timothy R, GALLANT, Michel, STURINO, Claudio, BOOKSER, Brett C, MELILLO, Vito, BAEK, Minson, VALDEZ, Lino, BECHARA, William Schulz, CLEMENS, Jeremy J
Year of Publication 06.04.2023
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Year of Publication 06.04.2023
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MODULATOR OF THE CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR, PHARMACEUTICAL COMPOSITIONS, METHODS OF TREATMENT, AND PROCESS FOR MAKING THE MODULATOR
Gross, Raymond Stanley, Ferris, Lori Ann, Hsia, Clara Kuang-Ju, Clemens, Jeremy J, Cleveland, Thomas, Uy, Johnny, Termin, Andreas P, Abela, Alexander Russell, Krenitsky, Paul John, Alcacio, Timothy, Gulevich, Anton V, Van Goor, Fredrick F, Pierre, Fabrice Jean Denis, Stavropoulos, Kathy, Shi, Yi, Angell, Paul Timothy, Khatuya, Haripada, Hughes, Robert M, Hadida Ruah, Sara Sabina, McCartney, Jason, Kang, Ping, Siesel, David Andrew, Baek, Minson, Grootenhuis, Peter Diederik Jan, Joshi, Pramod Virupax, Paraselli, Prasuna, Young, Timothy John, Zhou, Jinglan, Miller, Mark Thomas, Shrestha, Muna, Anderson, Corey, Keshavarz-Shokri, Ali
Year of Publication 09.11.2023
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Year of Publication 09.11.2023
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Modulator of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator
Mccartney, Jason, Cleveland, Thomas, Uy, Johnny, Mcauley-Aoki, Rachel, Termin, Andreas P, Abela, Alexander Russell, Krenitsky, Paul John, Alcacio, Timothy, Zhang, Beili, Pierre, Fabrice Jean Denis, Khatuya, Haripada, Hughes, Robert M, Hadida Ruah, Sara Sabina, Frieman, Bryan A, Busch, Brett Bradley, Siesel, David Andrew, Baek, Minson, Joshi, Pramod Virupax, Paraselli, Prasuna, Van Goor, Fredrick, Zhou, Jinglan, Miller, Mark Thomas, Melillo, Vito, Anderson, Corey, Grootenhuis, Peter, Keshavarz-Shokri, Ali
Year of Publication 28.04.2023
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Year of Publication 28.04.2023
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MODULATOR OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR, PHARMACEUTICAL COMPOSITIONS, METHODS OF TREATMENT, AND PROCESS FOR MAKING THE MODULATOR
Cleveland, Thomas, Uy, Johnny, McAuley-Aoki, Rachel, Termin, Andreas P, Abela, Alexander Russell, Krenitsky, Paul John, Alcacio, Timothy, Zhang, Beili, Pierre, Fabrice Jean Denis, Khatuya, Haripada, Hughes, Robert M, Hadida Ruah, Sara Sabina, McCartney, Jason, Frieman, Bryan A, Busch, Brett Bradley, Baek, Minson, Joshi, Pramod Virupax, Paraselli, Prasuna, Van Goor, Fredrick, Zhou, Jinglan, Miller, Mark Thomas, Melillo, Vito, Anderson, Corey, Grootenhuis, Peter, Keshavarz-Shokri, Ali
Year of Publication 29.09.2022
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Year of Publication 29.09.2022
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MODULATOR OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR, PHARMACEUTICAL COMPOSITIONS, METHODS OF TREATMENT, AND PROCESS FOR MAKING THE MODULATOR
KHATUYA, Haripada, HADIDA RUAH, Sara Sabina, YOUNG, Timothy John, FERRIS, Lori Ann, MCCARTNEY, Jason, CLEVELAND, Thomas, KANG, Ping, KESHAVARZ-SHOKRI, Ali, GROSS, Raymond Stanley, STAVROPOULOS, Kathy, ALCACIO, Timothy, HUGHES, Robert M, PIERRE, Fabrice Jean Denis, KRENITSKY, Paul John, ANGELL, Paul Timothy, GROOTENHUIS, Peter Diederik Jan, BAEK, Minson, SHI, Yi, SHRESTHA, Muna, CLEMENS, Jeremy J, ZHOU, Jinglan, ANDERSON, Corey, PARASELLI, Prasuna, MILLER, Mark Thomas, SIESEL, David Andrew, VAN GOOR, Fredrick F, HSIA, Clara Kuang-Ju, GULEVICH, Anton, TERMIN, Andreas P, UY, Johnny, ABELA, Alexander Russell, JOSHI, Pramond Virupax
Year of Publication 13.07.2023
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Year of Publication 13.07.2023
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MODULATOR OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR, PHARMACEUTICAL COMPOSITIONS, METHODS OF TREATMENT, AND PROCESS FOR MAKING THE MODULATOR
ANDREAS P TERMIN, VITO MELILLO, FREDRICK VAN GOOR, FABRICE JEAN DENIS PIERRE, BRETT BRADLEY BUSCH, PRASUNA PARASELLI, ALI KESHAVARZ-SHOKRI, THOMAS CLEVELAND, ALEXANDER RUSSELL ABELA, JOHNNY UY, TIMOTHY ALCACIO, PRAMOD VIRUPAX JOSHI, PAUL JOHN KRENITSKY, PETER GROOTENHUIS, ROBERT M HUGHES, SARA SABINA HADIDA RUAH, JASON MCCARTNEY, MINSON BAEK, RACHEL MCAULEY-AOKI, DAVID ANDREW SIESEL, JINGLAN ZHOU, MARK THOMAS MILLER, BEILI ZHANG, BRYAN A FRIEMAN, HARIPADA KHATUYA, COREY ANDERSON
Year of Publication 30.11.2022
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Year of Publication 30.11.2022
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MACROCYCLES CONTAINING A 1,3,4-OXADIAZOLE RING FOR USE AS MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR
HADIDA RUAH, SARA SABINA, GROOTENHUIS, PETER DIEDERIK JAN, BOOKSER, BRETT C, GALLANT, MICHEL, BECHARA, WILLIAM SCHULZ, STURINO, CLAUDIO, REDDY, THUMKUNTA JAGADEESWAR, ZHOU, JINGLAN, PARASELLI, PRASUNA, RAMTOHUL, YEEMAN K, CLEVELAND, THOMAS, VALDEZ, LINO, LATERREUR, JULIE, CLEMENS, JEREMY J, COON, TIMOTHY, MILLER, MARK THOMAS, BAEK, MINSON
Year of Publication 27.05.2022
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Year of Publication 27.05.2022
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MODULATOR OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR, PHARMACEUTICAL COMPOSITIONS, METHODS OF TREATMENT, AND PROCESS FOR MAKING THE MODULATOR
KHATUYA, Haripada, HADIDA RUAH, Sara Sabina, YOUNG, Timothy John, FERRIS, Lori Ann, MCCARTNEY, Jason, CLEVELAND, Thomas, KANG, Ping, KESHAVARZ-SHOKRI, Ali, GROSS, Raymond Stanley, STAVROPOULOS, Kathy, ALCACIO, Timothy, HUGHES, Robert M, PIERRE, Fabrice Jean Denis, KRENITSKY, Paul John, ANGELL, Paul Timothy, GROOTENHUIS, Peter Diederik Jan, BAEK, Minson, SHI, Yi, SHRESTHA, Muna, CLEMENS, Jeremy J, ZHOU, Jinglan, ANDERSON, Corey, PARASELLI, Prasuna, MILLER, Mark Thomas, SIESEL, David Andrew, VAN GOOR, Fredrick F, HSIA, Clara Kuang-Ju, GULEVICH, Anton, TERMIN, Andreas P, UY, Johnny, ABELA, Alexander Russell, JOSHI, Pramond Virupax
Year of Publication 06.04.2023
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Year of Publication 06.04.2023
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