The two extremes of Hansen’s disease—Different manifestations of leprosy and their biological consequences in an Avar Age (late 7th century CE) osteoarchaeological series of the Duna-Tisza Interfluve (Kiskundorozsma–Daruhalom-dűlő II, Hungary)
Spekker, Olga, Tihanyi, Balázs, Kis, Luca, Váradi, Orsolya Anna, Donoghue, Helen D., Minnikin, David E., Szalontai, Csaba, Vida, Tivadar, Pálfi, György, Marcsik, Antónia, Molnár, Erika
Published in PloS one (23.06.2022)
Published in PloS one (23.06.2022)
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Journal Article
The role of hydrophobicity in tuberculosis evolution and pathogenicity
Jankute, Monika, Nataraj, Vijayashankar, Lee, Oona Y-C, Wu, Houdini H T, Ridell, Malin, Garton, Natalie J, Barer, Michael R, Minnikin, David E, Bhatt, Apoorva, Besra, Gurdyal S
Published in Scientific reports (02.05.2017)
Published in Scientific reports (02.05.2017)
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Journal Article
Detection and Molecular Characterization of 9000-Year-Old Mycobacterium tuberculosis from a Neolithic Settlement in the Eastern Mediterranean
Hershkovitz, Israel, Donoghue, Helen D, Minnikin, David E, Besra, Gurdyal S, Lee, Oona Y-C, Gernaey, Angela M, Galili, Ehud, Eshed, Vered, Greenblatt, Charles L, Lemma, Eshetu, Bar-Gal, Gila Kahila, Spigelman, Mark
Published in PloS one (15.10.2008)
Published in PloS one (15.10.2008)
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Journal Article
Identification of a Desaturase Involved in Mycolic Acid Biosynthesis in Mycobacterium smegmatis
Singh, Albel, Varela, Cristian, Bhatt, Kiranmai, Veerapen, Natacha, Lee, Oona Y C, Wu, Houdini H T, Besra, Gurdyal S, Minnikin, David E, Fujiwara, Nagatoshi, Teramoto, Kanae, Bhatt, Apoorva
Published in PloS one (14.10.2016)
Published in PloS one (14.10.2016)
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Journal Article
Detection and strain typing of ancient Mycobacterium leprae from a medieval leprosy hospital
Taylor, G Michael, Tucker, Katie, Butler, Rachel, Pike, Alistair W G, Lewis, Jamie, Roffey, Simon, Marter, Philip, Lee, Oona Y-C, Wu, Houdini H T, Minnikin, David E, Besra, Gurdyal S, Singh, Pushpendra, Cole, Stewart T, Stewart, Graham R
Published in PloS one (30.04.2013)
Published in PloS one (30.04.2013)
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Journal Article
Osteological and biomolecular evidence of a 7000-year-old case of hypertrophic pulmonary osteopathy secondary to tuberculosis from neolithic hungary
Masson, Muriel, Molnár, Erika, Donoghue, Helen D, Besra, Gurdyal S, Minnikin, David E, Wu, Houdini H T, Lee, Oona Y-C, Bull, Ian D, Pálfi, György
Published in PloS one (30.10.2013)
Published in PloS one (30.10.2013)
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Journal Article
Tuberculosis in Dr Granville's mummy: a molecular re-examination of the earliest known Egyptian mummy to be scientifically examined and given a medical diagnosis
Donoghue, Helen D., Lee, Oona Y.-C., Minnikin, David E., Besra, Gurdyal S., Taylor, John H., Spigelman, Mark
Published in Proceedings of the Royal Society. B, Biological sciences (07.01.2010)
Published in Proceedings of the Royal Society. B, Biological sciences (07.01.2010)
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Journal Article
Osteological, biomolecular and geochemical examination of an early anglo-saxon case of lepromatous leprosy
Inskip, Sarah A, Taylor, G Michael, Zakrzewski, Sonia R, Mays, Simon A, Pike, Alistair W G, Llewellyn, Gareth, Williams, Christopher M, Lee, Oona Y-C, Wu, Houdini H T, Minnikin, David E, Besra, Gurdyal S, Stewart, Graham R
Published in PloS one (13.05.2015)
Published in PloS one (13.05.2015)
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Journal Article
Mycobacterium tuberculosis complex lipid virulence factors preserved in the 17,000-year-old skeleton of an extinct bison, Bison antiquus
Lee, Oona Y-C, Wu, Houdini H T, Donoghue, Helen D, Spigelman, Mark, Greenblatt, Charles L, Bull, Ian D, Rothschild, Bruce M, Martin, Larry D, Minnikin, David E, Besra, Gurdyal S
Published in PloS one (30.07.2012)
Published in PloS one (30.07.2012)
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Journal Article
MKAN27435 is required for the biosynthesis of higher subclasses of lipooligosaccharides in Mycobacterium kansasii
Nataraj, Vijayashankar, Pang, Poh-choo, Haslam, Stuart M, Veerapen, Natacha, Minnikin, David E, Dell, Anne, Besra, Gurdyal S, Bhatt, Apoorva
Published in PloS one (20.04.2015)
Published in PloS one (20.04.2015)
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Journal Article
Differential spontaneous folding of mycolic acids from Mycobacterium tuberculosis
Groenewald, Wilma, Baird, Mark S., Verschoor, Jan A., Minnikin, David E., Croft, Anna K.
Published in Chemistry and physics of lipids (01.05.2014)
Published in Chemistry and physics of lipids (01.05.2014)
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Journal Article
Positive Diagnosis of Ancient Leprosy and Tuberculosis Using Ancient DNA and Lipid Biomarkers
Donoghue, Helen, Taylor, G., Stewart, Graham, Lee, Oona, Wu, Houdini, Besra, Gurdyal, Minnikin, David
Published in Diversity (Basel) (01.12.2017)
Published in Diversity (Basel) (01.12.2017)
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Journal Article
Detection of Mycobacterium tuberculosis in sputum by gas chromatography-mass spectrometry of methyl mycocerosates released by thermochemolysis
O'Sullivan, Denise M, Nicoara, Simona C, Mutetwa, Reggie, Mungofa, Stanley, Lee, Oona Y-C, Minnikin, David E, Bardwell, Max W, Corbett, Elizabeth L, McNerney, Ruth, Morgan, Geraint H
Published in PloS one (05.03.2012)
Published in PloS one (05.03.2012)
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Journal Article
A Simple Mycobacterial Monomycolated Glycerol Lipid Has Potent Immunostimulatory Activity
Andersen, Claire S, Agger, Else Marie, Rosenkrands, Ida, Gomes, Jessica M, Bhowruth, Veemal, Gibson, Kevin J. C, Petersen, Rune V, Minnikin, David E, Besra, Gurdyal S, Andersen, Peter
Published in The Journal of immunology (1950) (01.01.2009)
Published in The Journal of immunology (1950) (01.01.2009)
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Journal Article
A Type II Pathway for Fatty Acid Biosynthesis Presents Drug Targets in Plasmodium falciparum
WALLER, Ross F, RALPH, Stuart A, REED, Michael B, SU, Vanessa, DOUGLAS, James D, MINNIKIN, David E, COWMAN, Alan F, BESRA, Gurdyal S, MCFADDEN, Geoffrey I
Published in Antimicrobial Agents and Chemotherapy (01.01.2003)
Published in Antimicrobial Agents and Chemotherapy (01.01.2003)
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Journal Article
Conformational behavior of oxygenated mycobacterial mycolic acids from Mycobacterium bovis BCG
Villeneuve, Masumi, Kawai, Mizuo, Watanabe, Motoko, Aoyagi, Yutaka, Hitotsuyanagi, Yukio, Takeya, Koichi, Gouda, Hiroaki, Hirono, Shuichi, Minnikin, David E., Nakahara, Hiroo
Published in Biochimica et biophysica acta (01.07.2007)
Published in Biochimica et biophysica acta (01.07.2007)
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Journal Article
LosA, a Key Glycosyltransferase Involved in the Biosynthesis of a Novel Family of Glycosylated Acyltrehalose Lipooligosaccharides from Mycobacterium marinum
Burguière, Adeline, Hitchen, Paul G., Dover, Lynn G., Kremer, Laurent, Ridell, Malin, Alexander, David C., Liu, Jun, Morris, Howard R., Minnikin, David E., Dell, Anne, Besra, Gurdyal S.
Published in The Journal of biological chemistry (23.12.2005)
Published in The Journal of biological chemistry (23.12.2005)
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