A model of lysosomal pH regulation
Ishida, Yoichi, Nayak, Smita, Mindell, Joseph A, Grabe, Michael
Published in The Journal of general physiology (01.06.2013)
Published in The Journal of general physiology (01.06.2013)
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Journal Article
The Cl - /H + antiporter ClC-7 is the primary chloride permeation pathway in lysosomes
Mindell, Joseph A, Graves, Austin R, Curran, Patricia K, Smith, Carolyn L
Published in Nature (London) (05.06.2008)
Published in Nature (London) (05.06.2008)
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Journal Article
Tonic inhibition of the chloride/proton antiporter ClC-7 by PI(3,5)P2 is crucial for lysosomal pH maintenance
Leray, Xavier, Hilton, Jacob K, Nwangwu, Kamsi, Becerril, Alissa, Mikusevic, Vedrana, Fitzgerald, Gabriel, Amin, Anowarul, Weston, Mary R, Mindell, Joseph A
Published in eLife (07.06.2022)
Published in eLife (07.06.2022)
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Journal Article
Exploring the K + binding site and its coupling to transport in the neurotransmitter:sodium symporter LeuT
Schmidt, Solveig G, Nygaard, Andreas, Mindell, Joseph A, Loland, Claus J
Published in eLife (25.01.2024)
Published in eLife (25.01.2024)
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Journal Article
Protons in small spaces: Discrete simulations of vesicle acidification
Singh, Apeksha, Marcoline, Frank V, Veshaguri, Salome, Kao, Aimee W, Bruchez, Marcel, Mindell, Joseph A, Stamou, Dimitrios, Grabe, Michael
Published in PLoS computational biology (01.12.2019)
Published in PLoS computational biology (01.12.2019)
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Journal Article
Molecular dynamics characterization of the mechanism of inhibition of ClC-7 activity by PI(3)P
Sefah, Eric, Hilton, Jacob K., Mindell, Joseph A., Grabe, Michael
Published in Biophysical journal (10.02.2023)
Published in Biophysical journal (10.02.2023)
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Journal Article
The effects of disease-causing ClC-7 mutations on lysosomal pH
Mikusevic, Vedrana, Hilton, Jacob K., Jethva, Reena, Mindell, Joseph A.
Published in Biophysical journal (10.02.2023)
Published in Biophysical journal (10.02.2023)
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Journal Article
Structure and inhibition mechanism of the human citrate transporter NaCT
Sauer, David B., Song, Jinmei, Wang, Bing, Hilton, Jacob K., Karpowich, Nathan K., Mindell, Joseph A., Rice, William J., Wang, Da-Neng
Published in Nature (London) (04.03.2021)
Published in Nature (London) (04.03.2021)
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Journal Article
The chloride antiporter CLCN7 is a modifier of lysosome dysfunction in FIG4 and VAC14 mutants
Cao, Xu, Lenk, Guy M, Mikusevic, Vedrana, Mindell, Joseph A, Meisler, Miriam H
Published in PLoS genetics (26.06.2023)
Published in PLoS genetics (26.06.2023)
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Journal Article
The bacterial dicarboxylate transporter VcINDY uses a two-domain elevator-type mechanism
Mulligan, Christopher, Fenollar-Ferrer, Cristina, Fitzgerald, Gabriel A, Vergara-Jaque, Ariela, Kaufmann, Desirée, Li, Yan, Forrest, Lucy R, Mindell, Joseph A
Published in Nature structural & molecular biology (01.03.2016)
Published in Nature structural & molecular biology (01.03.2016)
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Journal Article