Antitumor Activity of TZT-1027 (Soblidotin)
WATANABE, Junicmi, MINAMI, Megumi, KOBAYASHI, Motohiro
Published in Anticancer research (01.05.2006)
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Published in Anticancer research (01.05.2006)
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Synthesis and Antitumor Activity of Novel Pyrimidinyl Pyrazole Derivatives. III. Synthesis and Antitumor Activity of 3-Phenylpiperazinyl-1-trans-propenes
Naito, Hiroyuki, Ohsuki, Satoru, Atsumi, Ryo, Minami, Megumi, Mochizuki, Mineko, Hirotani, Kenji, Kumazawa, Eiji, Ejima, Akio
Published in Chemical & pharmaceutical bulletin (01.02.2005)
Published in Chemical & pharmaceutical bulletin (01.02.2005)
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Synthesis and Antitumor Activity of Novel Pyrimidinyl Pyrazole Derivatives. II. Optimization of the Phenylpiperazine Moiety of 1-[5-Methyl-1-(2-pyrimidinyl)-4-pyrazolyl]-3-phenylpiperazinyl-1-trans-propenes
Naito, Hiroyuki, Ohsuki, Satoru, Sugimori, Masamichi, Atsumi, Ryo, Minami, Megumi, Nakamura, Yoshihide, Ishii, Mineko, Hirotani, Kenji, Kumazawa, Eiji, Ejima, Akio
Published in Chemical & pharmaceutical bulletin (01.04.2002)
Published in Chemical & pharmaceutical bulletin (01.04.2002)
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DX‐8951F, a water‐soluble camptothecin analog, exhibits potent antitumor activity against a human lung cancer cell line and its SN‐38‐resistant variant
Joto, Noriko, Ishii, Mineko, Minami, Megumi, Kuga, Hiroshi, Mitsui, Ikuo, Tohgo, Akiko
Published in International journal of cancer (07.08.1997)
Published in International journal of cancer (07.08.1997)
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Growth inhibitory effect of a new camptothecin analog, DX-8951f, on various drug-resistant sublines including BCRP-mediated camptothecin derivative-resistant variants derived from the human lung cancer cell line PC-6
Ishii, M, Iwahana, M, Mitsui, I, Minami, M, Imagawa, S, Tohgo, A, Ejima, A
Published in Anti-cancer drugs (01.06.2000)
Published in Anti-cancer drugs (01.06.2000)
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Synthesis, activity, and their relationships of 2,4-diaminonicotinamide derivatives as EGFR inhibitors targeting C797S mutation
Kageji, Hideaki, Momose, Takayuki, Nagamoto, Yasuhito, Togashi, Noriko, Yasumatsu, Isao, Nishikawa, Yosuke, Kihara, Kawori, Hiramoto, Kumiko, Minami, Megumi, Kasanuki, Naomi, Isoyama, Takeshi, Naito, Hiroyuki
Published in Bioorganic & medicinal chemistry letters (15.01.2024)
Published in Bioorganic & medicinal chemistry letters (15.01.2024)
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4-Pyridone-3-carboxylic acid as a benzoic acid bioisostere: Design, synthesis, and evaluation of EP300/CBP histone acetyltransferase inhibitors
Kanada, Ryutaro, Suzuki, Takashi, Murata, Takeshi, Miyazaki, Masaki, Shimada, Takashi, Kuroha, Mutsumi, Minami, Megumi, Higuchi, Saito, Tominaga, Yuichi, Naito, Hiroyuki
Published in Bioorganic & medicinal chemistry letters (01.11.2021)
Published in Bioorganic & medicinal chemistry letters (01.11.2021)
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Discovery of a potent, selective, and orally available EGFR C797S mutant inhibitor (DS06652923) with in vivo antitumor activity
Kageji, Hideaki, Momose, Takayuki, Ebisawa, Masayuki, Nakazawa, Yusuke, Okada, Hiroyuki, Togashi, Noriko, Nagamoto, Yasuhito, Obuchi, Wataru, Yasumatsu, Isao, Kihara, Kawori, Hiramoto, Kumiko, Minami, Megumi, Kasanuki, Naomi, Isoyama, Takeshi, Naito, Hiroyuki, Tanaka, Naoki
Published in Bioorganic & medicinal chemistry (01.09.2024)
Published in Bioorganic & medicinal chemistry (01.09.2024)
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Abstract LB-264: Autophagy modulates intracellular dynamics of [fam-] trastuzumab deruxtecan (DS-8201a), a novel HER2 antibody-drug conjugate (HER2-ADC)
Abe, Manabu, Nagata, Motoko, Koyama, Kumiko, Yasuda, Satoru, Hirata, Tsuyoshi, Kuwahara, Yusuke, Inaki, Koichiro, Kasanuki, Naomi, Minami, Megumi, Hagihara, Katsunobu, Wakita, Kenichi, Slosberg, Eric, Murakami, Masato
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Antitumor bicyclic hexapeptide RA-VII modulates cyclin D1 protein level
Wakita Ki, Minami, M, Venkateswarlu, A, Sharma, V M, Ramesh, M, Akahane, K
Published in Anti-cancer drugs (01.06.2001)
Published in Anti-cancer drugs (01.06.2001)
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Abstract 4891: Ifinatamab deruxtecan (I-DXd), a novel B7-H3-targeting antibody-drug conjugate, demonstrates efficient payload delivery into tumor through target-dependent internalization
Katsumata, Len, Deguchi, Tsuneo, Hasegawa, Jun, Yamato, Michiko, Nishiya, Yumi, Watanabe, Akiko, Honda, Tomoyo, Minami, Megumi, Kasanuki, Naomi, Maejima, Takanori, Muramatsu, Sumie, Herrmann, Monika, Schulte, Nina, Polier, Gernot, Wang, Xuya, Yoshida, Takanori, Izumi, Nanae, Qian, Xiaozhong, Agatsuma, Toshinori, Nakamaru, Kenji
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Synthesis and mechanism of action of novel pyrimidinyl pyrazole derivatives possessing antiproliferative activity
Ohki, Hitoshi, Hirotani, Kenji, Naito, Hiroyuki, Ohsuki, Satoru, Minami, Megumi, Ejima, Akio, Koiso, Yukiko, Hashimoto, Yuichi
Published in Bioorganic & medicinal chemistry letters (04.11.2002)
Published in Bioorganic & medicinal chemistry letters (04.11.2002)
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