CAR T cell immunotherapy for human cancer
June, Carl H, O'Connor, Roddy S, Kawalekar, Omkar U, Ghassemi, Saba, Milone, Michael C
Published in Science (American Association for the Advancement of Science) (23.03.2018)
Published in Science (American Association for the Advancement of Science) (23.03.2018)
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Precision targeting of autoantigen-specific B cells in muscle-specific tyrosine kinase myasthenia gravis with chimeric autoantibody receptor T cells
Oh, Sangwook, Mao, Xuming, Manfredo-Vieira, Silvio, Lee, Jinmin, Patel, Darshil, Choi, Eun Jung, Alvarado, Andrea, Cottman-Thomas, Ebony, Maseda, Damian, Tsao, Patricia Y., Ellebrecht, Christoph T., Khella, Sami L., Richman, David P., O’Connor, Kevin C., Herzberg, Uri, Binder, Gwendolyn K., Milone, Michael C., Basu, Samik, Payne, Aimee S.
Published in Nature biotechnology (01.09.2023)
Published in Nature biotechnology (01.09.2023)
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Journal Article
Reengineering chimeric antigen receptor T cells for targeted therapy of autoimmune disease
Ellebrecht, Christoph T., Bhoj, Vijay G., Nace, Arben, Choi, Eun Jung, Mao, Xuming, Cho, Michael Jeffrey, Di Zenzo, Giovanni, Lanzavecchia, Antonio, Seykora, John T., Cotsarelis, George, Milone, Michael C., Payne, Aimee S.
Published in Science (American Association for the Advancement of Science) (08.07.2016)
Published in Science (American Association for the Advancement of Science) (08.07.2016)
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Journal Article
Chimeric Antigen Receptor–Modified T Cells for Acute Lymphoid Leukemia
Grupp, Stephan A, Kalos, Michael, Barrett, David, Aplenc, Richard, Porter, David L, Rheingold, Susan R, Teachey, David T, Chew, Anne, Hauck, Bernd, Wright, J. Fraser, Milone, Michael C, Levine, Bruce L, June, Carl H
Published in The New England journal of medicine (18.04.2013)
Published in The New England journal of medicine (18.04.2013)
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Journal Article
B cell maturation antigen-specific CAR T cells are clinically active in multiple myeloma
Cohen, Adam D, Garfall, Alfred L, Stadtmauer, Edward A, Melenhorst, J Joseph, Lacey, Simon F, Lancaster, Eric, Vogl, Dan T, Weiss, Brendan M, Dengel, Karen, Nelson, Annemarie, Plesa, Gabriela, Chen, Fang, Davis, Megan M, Hwang, Wei-Ting, Young, Regina M, Brogdon, Jennifer L, Isaacs, Randi, Pruteanu-Malinici, Iulian, Siegel, Don L, Levine, Bruce L, June, Carl H, Milone, Michael C
Published in The Journal of clinical investigation (01.06.2019)
Published in The Journal of clinical investigation (01.06.2019)
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Journal Article
Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells
Kawalekar, Omkar U., O’Connor, Roddy S., Fraietta, Joseph A., Guo, Lili, McGettigan, Shannon E., Posey, Avery D., Patel, Prachi R., Guedan, Sonia, Scholler, John, Keith, Brian, Snyder, Nathaniel W., Blair, Ian A., Milone, Michael C., June, Carl H.
Published in Immunity (Cambridge, Mass.) (16.02.2016)
Published in Immunity (Cambridge, Mass.) (16.02.2016)
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Journal Article
Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia
Porter, David L, Hwang, Wei-Ting, Frey, Noelle V, Lacey, Simon F, Shaw, Pamela A, Loren, Alison W, Bagg, Adam, Marcucci, Katherine T, Shen, Angela, Gonzalez, Vanessa, Ambrose, David, Grupp, Stephan A, Chew, Anne, Zheng, Zhaohui, Milone, Michael C, Levine, Bruce L, Melenhorst, Jan J, June, Carl H
Published in Science translational medicine (02.09.2015)
Published in Science translational medicine (02.09.2015)
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Journal Article
Pharmacology of Chimeric Antigen Receptor-Modified T Cells
Song, Edward Z, Milone, Michael C
Published in Annual review of pharmacology and toxicology (06.01.2021)
Published in Annual review of pharmacology and toxicology (06.01.2021)
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Journal Article
Antigen-specific B cell depletion for precision therapy of mucosal pemphigus vulgaris
Lee, Jinmin, Lundgren, Daniel K, Mao, Xuming, Manfredo-Vieira, Silvio, Nunez-Cruz, Selene, Williams, Erik F, Assenmacher, Charles-Antoine, Radaelli, Enrico, Oh, Sangwook, Wang, Baomei, Ellebrecht, Christoph T, Fraietta, Joseph A, Milone, Michael C, Payne, Aimee S
Published in The Journal of clinical investigation (01.12.2020)
Published in The Journal of clinical investigation (01.12.2020)
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Journal Article
Efficacy and Safety of Hydroxychloroquine vs Placebo for Pre-exposure SARS-CoV-2 Prophylaxis Among Health Care Workers: A Randomized Clinical Trial
Abella, Benjamin S, Jolkovsky, Eliana L, Biney, Barbara T, Uspal, Julie E, Hyman, Matthew C, Frank, Ian, Hensley, Scott E, Gill, Saar, Vogl, Dan T, Maillard, Ivan, Babushok, Daria V, Huang, Alexander C, Nasta, Sunita D, Walsh, Jennifer C, Wiletyo, E Paul, Gimotty, Phyllis A, Milone, Michael C, Amaravadi, Ravi K
Published in JAMA internal medicine (01.02.2021)
Published in JAMA internal medicine (01.02.2021)
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Journal Article
The Pharmacology of T Cell Therapies
Milone, Michael C, Bhoj, Vijay G
Published in Molecular therapy. Methods & clinical development (16.03.2018)
Published in Molecular therapy. Methods & clinical development (16.03.2018)
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Journal Article
Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis
Xiang, Yan, Stine, Zachary E, Xia, Jinsong, Lu, Yunqi, O'Connor, Roddy S, Altman, Brian J, Hsieh, Annie L, Gouw, Arvin M, Thomas, Ajit G, Gao, Ping, Sun, Linchong, Song, Libing, Yan, Benedict, Slusher, Barbara S, Zhuo, Jingli, Ooi, London L, Lee, Caroline G L, Mancuso, Anthony, McCallion, Andrew S, Le, Anne, Milone, Michael C, Rayport, Stephen, Felsher, Dean W, Dang, Chi V
Published in The Journal of clinical investigation (01.06.2015)
Published in The Journal of clinical investigation (01.06.2015)
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Journal Article
A human orthogonal IL-2 and IL-2Rβ system enhances CAR T cell expansion and antitumor activity in a murine model of leukemia
Zhang, Qian, Hresko, Morgan E, Picton, Lora K, Su, Leon, Hollander, Michael J, Nunez-Cruz, Selene, Zhang, Zheng, Assenmacher, Charles-Antoine, Sockolosky, Jonathan T, Garcia, K Christopher, Milone, Michael C
Published in Science translational medicine (22.12.2021)
Published in Science translational medicine (22.12.2021)
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Journal Article
Multifactorial T-cell Hypofunction That Is Reversible Can Limit the Efficacy of Chimeric Antigen Receptor―Transduced Human T cells in Solid Tumors
MOON, Edmund K, WANG, Liang-Chuan, JUNE, Carl H, RILEY, James L, WHERRY, E. John, ALBELDA, Steven M, DOLFI, Douglas V, WILSON, Caleph B, RANGANATHAN, Raghuveer, JING SUN, KAPOOR, Veena, SCHOLLER, John, PURE, Ellen, MILONE, Michael C
Published in Clinical cancer research (15.08.2014)
Published in Clinical cancer research (15.08.2014)
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Journal Article
Substrate rigidity regulates human T cell activation and proliferation
O'Connor, Roddy S, Hao, Xueli, Shen, Keyue, Bashour, Keenan, Akimova, Tatiana, Hancock, Wayne W, Kam, Lance C, Milone, Michael C
Published in The Journal of immunology (1950) (01.08.2012)
Published in The Journal of immunology (1950) (01.08.2012)
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