Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment
Zemek, Rachael M, De Jong, Emma, Chin, Wee Loong, Schuster, Iona S, Fear, Vanessa S, Casey, Thomas H, Forbes, Cath, Dart, Sarah J, Leslie, Connull, Zaitouny, Ayham, Small, Michael, Boon, Louis, Forrest, Alistair R R, Muiri, Daithi O, Degli-Esposti, Mariapia A, Millward, Michael J, Nowak, Anna K, Lassmann, Timo, Bosco, Anthony, Lake, Richard A, Lesterhuis, W Joost
Published in Science translational medicine (17.07.2019)
Published in Science translational medicine (17.07.2019)
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Pamiparib in combination with tislelizumab in patients with advanced solid tumours: results from the dose-escalation stage of a multicentre, open-label, phase 1a/b trial
Friedlander, Michael, Prof, Meniawy, Tarek, PhD, Markman, Ben, MBBS, Mileshkin, Linda, MD, Harnett, Paul, Prof, Millward, Michael, MBBS, Lundy, Joanne, MBBS, Freimund, Alison, MBBS, Norris, Christie, RN, Mu, Song, PhD, Wu, John, PhD, Paton, Virginia, PharmD, Gao, Bo, PhD
Published in The lancet oncology (01.09.2019)
Published in The lancet oncology (01.09.2019)
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Sensitizing the Tumor Microenvironment to Immune Checkpoint Therapy
Zemek, Rachael M, Chin, Wee Loong, Nowak, Anna K, Millward, Michael J, Lake, Richard A, Lesterhuis, W Joost
Published in Frontiers in immunology (18.02.2020)
Published in Frontiers in immunology (18.02.2020)
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Dabrafenib in BRAF -mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial
Hauschild, Axel, Prof, Grob, Jean-Jacques, Prof, Demidov, Lev V, Prof, Jouary, Thomas, MD, Gutzmer, Ralf, MD, Millward, Michael, MD, Rutkowski, Piotr, PhD, Blank, Christian U, PhD, Miller, Wilson H, PhD, Kaempgen, Eckhart, PhD, Martín-Algarra, Salvador, PhD, Karaszewska, Boguslawa, MD, Mauch, Cornelia, Prof, Chiarion-Sileni, Vanna, MD, Martin, Anne-Marie, PhD, Swann, Suzanne, PhD, Haney, Patricia, BSN, Mirakhur, Beloo, PhD, Guckert, Mary E, MSN, Goodman, Vicki, MD, Chapman, Paul B, MD
Published in The Lancet (British edition) (28.07.2012)
Published in The Lancet (British edition) (28.07.2012)
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Secreted frizzled-related protein 4 inhibits glioma stem-like cells by reversing epithelial to mesenchymal transition, inducing apoptosis and decreasing cancer stem cell properties
Bhuvanalakshmi, G, Arfuso, Frank, Millward, Michael, Dharmarajan, Arun, Warrier, Sudha
Published in PloS one (01.06.2015)
Published in PloS one (01.06.2015)
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Phase I Clinical Trial of Marizomib (NPI-0052) in Patients with Advanced Malignancies Including Multiple Myeloma: Study NPI-0052-102 Final Results
Harrison, Simon J, Mainwaring, Paul, Price, Timothy, Millward, Michael J, Padrik, Peeter, Underhill, Craig R, Cannell, Paul K, Reich, Steven D, Trikha, Mohit, Spencer, Andrew
Published in Clinical cancer research (15.09.2016)
Published in Clinical cancer research (15.09.2016)
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Temporally restricted activation of IFNβ signaling underlies response to immune checkpoint therapy in mice
Zemek, Rachael M., Chin, Wee Loong, Fear, Vanessa S., Wylie, Ben, Casey, Thomas H., Forbes, Cath, Tilsed, Caitlin M., Boon, Louis, Guo, Belinda B., Bosco, Anthony, Forrest, Alistair R. R., Millward, Michael J., Nowak, Anna K., Lake, Richard A., Lassmann, Timo, Lesterhuis, W. Joost
Published in Nature communications (19.08.2022)
Published in Nature communications (19.08.2022)
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Phase II Study of the MEK1/MEK2 Inhibitor Trametinib in Patients With Metastatic BRAF-Mutant Cutaneous Melanoma Previously Treated With or Without a BRAF Inhibitor
KIM, Kevin B, KEFFORD, Richard, GONZALEZ, Rene, OTT, Patrick A, LONG, Georgina V, GARDNER, Olivia S, OUELLET, Daniele, YANMEI XU, DEMARINI, Douglas J, LE, Ngocdiep T, PATEL, Kiran, LEWIS, Karl D, PAVLICK, Anna C, INFANTE, Jeffrey R, RIBAS, Antoni, SOSMAN, Jeffrey A, FECHER, Leslie A, MILLWARD, Michael, MCARTHUR, GrantA, HWU, Patrick
Published in Journal of clinical oncology (01.02.2013)
Published in Journal of clinical oncology (01.02.2013)
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Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial
Falchook, Gerald S, Dr, Long, Georgina V, PhD, Kurzrock, Razelle, Prof, Kim, Kevin B, MD, Arkenau, Tobias H, PhD, Brown, Michael P, PhD, Hamid, Omid, MD, Infante, Jeffrey R, MD, Millward, Michael, MD, Pavlick, Anna C, MD, O’Day, Steven J, MD, Blackman, Samuel C, PhD, Curtis, C Martin, BA, Lebowitz, Peter, PhD, Ma, Bo, PhD, Ouellet, Daniele, PhD, Kefford, Richard F, Prof
Published in The Lancet (British edition) (19.05.2012)
Published in The Lancet (British edition) (19.05.2012)
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Longitudinal Monitoring of ctDNA in Patients with Melanoma and Brain Metastases Treated with Immune Checkpoint Inhibitors
Lee, Jenny H, Menzies, Alexander M, Carlino, Matteo S, McEvoy, Ashleigh C, Sandhu, Shahneen, Weppler, Alison M, Diefenbach, Russell J, Dawson, Sarah-Jane, Kefford, Richard F, Millward, Michael J, Al-Ogaili, Zeyad, Tra, Thien, Gray, Elin S, Wong, Stephen Q, Scolyer, Richard A, Long, Georgina V, Rizos, Helen
Published in Clinical cancer research (01.08.2020)
Published in Clinical cancer research (01.08.2020)
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A Phase I Study of LY3009120, a Pan-RAF Inhibitor, in Patients with Advanced or Metastatic Cancer
Sullivan, Ryan J, Hollebecque, Antoine, Flaherty, Keith T, Shapiro, Geoffrey I, Rodon Ahnert, Jordi, Millward, Michael J, Zhang, Wei, Gao, Ling, Sykes, Amanda, Willard, Melinda D, Yu, Danni, Schade, Andrew E, Crowe, KrisAnne, Flynn, Daniel L, Kaufman, Michael D, Henry, James R, Peng, Sheng-Bin, Benhadji, Karim A, Conti, Ilaria, Gordon, Michael S, Tiu, Ramon V, Hong, David S
Published in Molecular cancer therapeutics (01.02.2020)
Published in Molecular cancer therapeutics (01.02.2020)
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Indwelling pleural catheters reduce inpatient days over pleurodesis for malignant pleural effusion
Fysh, Edward T H, Waterer, Grant W, Kendall, Peter A, Bremner, Peter R, Dina, Sharifa, Geelhoed, Elizabeth, McCarney, Kate, Morey, Sue, Millward, Michael, Musk, A W Bill, Lee, Y C Gary
Published in Chest (01.08.2012)
Published in Chest (01.08.2012)
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Correlation between circulating tumour DNA and metabolic tumour burden in metastatic melanoma patients
McEvoy, Ashleigh C, Warburton, Lydia, Al-Ogaili, Zeyad, Celliers, Liesl, Calapre, Leslie, Pereira, Michelle R, Khattak, Muhammad A, Meniawy, Tarek M, Millward, Michael, Ziman, Melanie, Gray, Elin S
Published in BMC cancer (09.07.2018)
Published in BMC cancer (09.07.2018)
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Changes in expression of PD-L1 on peripheral T cells in patients with melanoma and lung cancer treated with PD-1 inhibitors
Dart, Sarah J., Cook, Alistair M., Millward, Michael J., McDonnell, Alison M., Chin, Wee L., Hakeem, Muhammad U., Meniawy, Tarek M., Bowyer, Samantha E.
Published in Scientific reports (28.07.2021)
Published in Scientific reports (28.07.2021)
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Bilateral murine tumor models for characterizing the response to immune checkpoint blockade
Zemek, Rachael M., Fear, Vanessa S., Forbes, Cath, de Jong, Emma, Casey, Thomas H., Boon, Louis, Lassmann, Timo, Bosco, Anthony, Millward, Michael J., Nowak, Anna K., Lake, Richard A., Lesterhuis, W. Joost
Published in Nature protocols (01.05.2020)
Published in Nature protocols (01.05.2020)
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A Phase II Study of AT-101 (Gossypol) in Chemotherapy-Sensitive Recurrent Extensive-Stage Small Cell Lung Cancer
Baggstrom, Maria Q., Qi, Yingwei, Koczywas, Marianna, Argiris, Athanassios, Johnson, Elizabeth A., Millward, Michael J., Murphy, Sara C., Erlichman, Charles, Rudin, Charles M., Govindan, Ramaswamy
Published in Journal of thoracic oncology (01.10.2011)
Published in Journal of thoracic oncology (01.10.2011)
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Detectable ctDNA at the time of treatment cessation of ipilimumab and nivolumab for toxicity predicts disease progression in advanced melanoma patients
Warburton, Lydia, Reid, Anna, Amanuel, Benhur, Calapre, Leslie, Millward, Michael, Gray, Elin
Published in Frontiers in oncology (19.12.2023)
Published in Frontiers in oncology (19.12.2023)
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Circulating tumour DNA (ctDNA) as a biomarker in metachronous melanoma and colorectal cancer- a case report
Calapre, Leslie, Warburton, Lydia, Millward, Michael, Gray, Elin S
Published in BMC cancer (14.11.2019)
Published in BMC cancer (14.11.2019)
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Bcl-2 Antisense (oblimersen sodium) Plus Dacarbazine in Patients With Advanced Melanoma: The Oblimersen Melanoma Study Group
BEDIKIAN, Agop Y, MILLWARD, Michael, KIRKWOOD, John M, HALUSKA, Frank G, PEHAMBERGER, Hubert, CORNY, Robert, GORE, Martin, TREFZER, Uwe, PAVLICK, Anna C, DECONTI, Ronald, HERSH, Evan M, HERSEY, Peter
Published in Journal of clinical oncology (10.10.2006)
Published in Journal of clinical oncology (10.10.2006)
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