Model‐informed drug development of autologous CAR‐T cell therapy: Strategies to optimize CAR‐T cell exposure leveraging cell kinetic/dynamic modeling
Mc Laughlin, Anna M., Milligan, Peter A., Yee, Cassian, Bergstrand, Martin
Published in CPT: pharmacometrics and systems pharmacology (01.11.2023)
Published in CPT: pharmacometrics and systems pharmacology (01.11.2023)
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Journal Article
Pharmacokinetics, Safety, and Tolerability of Voriconazole in Immunocompromised Children
WALSH, Thomas J, DRISCOLL, Timothy, MILLIGAN, Peter A, WOOD, Nolan D, SCHLAMM, Haran, GROLL, Andreas H, JAFRI, Hasan, ARRIETA, Antonio C, KLEIN, Nigel J, LUTSAR, Irja
Published in Antimicrobial Agents and Chemotherapy (01.10.2010)
Published in Antimicrobial Agents and Chemotherapy (01.10.2010)
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Journal Article
Model Informed Drug Development: Collaboration Through A Common Framework
Anziano, Richard J., Milligan, Peter A.
Published in Clinical pharmacology and therapeutics (01.11.2021)
Published in Clinical pharmacology and therapeutics (01.11.2021)
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Journal Article
Model-based prediction of progression-free survival in patients with first-line renal cell carcinoma using week 8 tumor size change from baseline
Claret, Laurent, Zheng, Jenny, Mercier, Francois, Chanu, Pascal, Chen, Ying, Rosbrook, Brad, Yazdi, Pithavala, Milligan, Peter A., Bruno, Rene
Published in Cancer chemotherapy and pharmacology (01.09.2016)
Published in Cancer chemotherapy and pharmacology (01.09.2016)
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Journal Article
A pharmacokinetic-pharmacodynamic model for the quantitative prediction of dofetilide clinical QT prolongation from human ether-a-go-go-related gene current inhibition data
Jonker, Daniël M, Kenna, Leslie A, Leishman, Derek, Wallis, Rob, Milligan, Peter A, Jonsson, E Niclas
Published in Clinical pharmacology and therapeutics (01.06.2005)
Published in Clinical pharmacology and therapeutics (01.06.2005)
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Journal Article
Population pharmacokinetic modelling of darifenacin and its hydroxylated metabolite using pooled data, incorporating saturable first‐pass metabolism, CYP2D6 genotype and formulation‐dependent bioavailability
Kerbusch, Thomas, Wählby, Ulrika, Milligan, Peter A., Karlsson, Mats O.
Published in British journal of clinical pharmacology (01.12.2003)
Published in British journal of clinical pharmacology (01.12.2003)
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Journal Article
Assessing the efficiency of mixed effects modelling in quantifying metabolism based drug-drug interactions: using in vitro data as an aid to assess study power
Johnson, Trevor N., Kerbusch, Thomas, Jones, Barry, Tucker, Geoffrey T., Rostami-Hodjegan, Amin, Milligan, Peter A.
Published in Pharmaceutical statistics : the journal of the pharmaceutical industry (01.07.2009)
Published in Pharmaceutical statistics : the journal of the pharmaceutical industry (01.07.2009)
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Journal Article
Assessment of the relative in vivo potency of the hydroxylated metabolite of darifenacin in its ability to decrease salivary flow using pooled population pharmacokinetic–pharmacodynamic data
Kerbusch, Thomas, Milligan, Peter A., Karlsson, Mats O.
Published in British journal of clinical pharmacology (01.02.2004)
Published in British journal of clinical pharmacology (01.02.2004)
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Journal Article
Predicting Reductions in Chronic Obstructive Pulmonary Disease (COPD) Exacerbations from FEV1-A Model-Based Meta-Analysis of Literature Data from Controlled Randomized Clinical Trials
Ribbing, Jakob, Korell, Julia, Cerasoli, Frank, Milligan, Peter A., Martin, Steven W., Karlsson, Mats O.
Published in Journal of pharmacokinetics and pharmacodynamics (2015)
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Published in Journal of pharmacokinetics and pharmacodynamics (2015)
Journal Article