Distinct Tau Prion Strains Propagate in Cells and Mice and Define Different Tauopathies
Sanders, David W., Kaufman, Sarah K., DeVos, Sarah L., Sharma, Apurwa M., Mirbaha, Hilda, Li, Aimin, Barker, Scarlett J., Foley, Alex C., Thorpe, Julian R., Serpell, Louise C., Miller, Timothy M., Grinberg, Lea T., Seeley, William W., Diamond, Marc I.
Published in Neuron (Cambridge, Mass.) (18.06.2014)
Published in Neuron (Cambridge, Mass.) (18.06.2014)
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Tau Prion Strains Dictate Patterns of Cell Pathology, Progression Rate, and Regional Vulnerability In Vivo
Kaufman, Sarah K., Sanders, David W., Thomas, Talitha L., Ruchinskas, Allison J., Vaquer-Alicea, Jaime, Sharma, Apurwa M., Miller, Timothy M., Diamond, Marc I.
Published in Neuron (Cambridge, Mass.) (23.11.2016)
Published in Neuron (Cambridge, Mass.) (23.11.2016)
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Increased 4R-Tau Induces Pathological Changes in a Human-Tau Mouse Model
Schoch, Kathleen M., DeVos, Sarah L., Miller, Rebecca L., Chun, Seung J., Norrbom, Michaela, Wozniak, David F., Dawson, Hana N., Bennett, C. Frank, Rigo, Frank, Miller, Timothy M.
Published in Neuron (Cambridge, Mass.) (01.06.2016)
Published in Neuron (Cambridge, Mass.) (01.06.2016)
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RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia
Zu, Tao, Liu, Yuanjing, Bañez-Coronel, Monica, Reid, Tammy, Pletnikova, Olga, Lewis, Jada, Miller, Timothy M, Harms, Matthew B, Falchook, Annet E, Subramony, S H, Ostrow, Lyle W, Rothstein, Jeffrey D, Troncoso, Juan C, Ranum, Laura P W
Published in Proceedings of the National Academy of Sciences - PNAS (17.12.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (17.12.2013)
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Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds
Holmes, Brandon B, DeVos, Sarah L, Kfoury, Najla, Li, Mei, Jacks, Rachel, Yanamandra, Kiran, Ouidja, Mohand O, Brodsky, Frances M, Marasa, Jayne, Bagchi, Devika P, Kotzbauer, Paul T, Miller, Timothy M, Papy-Garcia, Dulce, Diamond, Marc I
Published in Proceedings of the National Academy of Sciences - PNAS (13.08.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (13.08.2013)
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Amyotrophic lateral sclerosis onset is influenced by the burden of rare variants in known amyotrophic lateral sclerosis genes
Cady, Janet, Allred, Peggy, Bali, Taha, Pestronk, Alan, Goate, Alison, Miller, Timothy M., Mitra, Robi D., Ravits, John, Harms, Matthew B., Baloh, Robert H.
Published in Annals of neurology (01.01.2015)
Published in Annals of neurology (01.01.2015)
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Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation
Kanekura, Kohsuke, Yagi, Takuya, Cammack, Alexander J, Mahadevan, Jana, Kuroda, Masahiko, Harms, Matthew B, Miller, Timothy M, Urano, Fumihiko
Published in Human molecular genetics (01.05.2016)
Published in Human molecular genetics (01.05.2016)
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Method for widespread microRNA-155 inhibition prolongs survival in ALS-model mice
Koval, Erica D, Shaner, Carey, Zhang, Peter, du Maine, Xavier, Fischer, Kimberlee, Tay, Jia, Chau, B Nelson, Wu, Gregory F, Miller, Timothy M
Published in Human molecular genetics (15.10.2013)
Published in Human molecular genetics (15.10.2013)
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An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study
Miller, Timothy M, Dr, Pestronk, Alan, Prof, David, William, MD, Rothstein, Jeffrey, Prof, Simpson, Ericka, MD, Appel, Stanley H, Prof, Andres, Patricia L, MS, Mahoney, Katy, BA, Allred, Peggy, DPT, Alexander, Katie, BA, Ostrow, Lyle W, MD, Schoenfeld, David, Prof, Macklin, Eric A, PhD, Norris, Daniel A, PhD, Manousakis, Georgios, MD, Crisp, Matthew, BS, Smith, Richard, MD, Bennett, C Frank, PhD, Bishop, Kathie M, PhD, Cudkowicz, Merit E, Prof
Published in Lancet neurology (01.05.2013)
Published in Lancet neurology (01.05.2013)
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Targeted ASO-mediated Atp1a2 knockdown in astrocytes reduces SOD1 aggregation and accelerates disease onset in mutant SOD1 mice
Iyer, Abhirami K, Schoch, Kathleen M, Verbeck, Anthony, Galasso, Grant, Chen, Hao, Smith, Sarah, Oldenborg, Anna, Miller, Timothy M, Karch, Celeste M, Bonni, Azad
Published in PloS one (28.11.2023)
Published in PloS one (28.11.2023)
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Amyotrophic lateral sclerosis care and research in the United States during the COVID‐19 pandemic: Challenges and opportunities
Andrews, Jinsy A., Berry, James D., Baloh, Robert H., Carberry, Nathan, Cudkowicz, Merit E., Dedi, Brixhilda, Glass, Jonathan, Maragakis, Nicholas J., Miller, Timothy M., Paganoni, Sabrina, Rothstein, Jeffrey D., Shefner, Jeremy M., Simmons, Zachary, Weiss, Michael D., Bedlack, Richard S.
Published in Muscle & nerve (01.08.2020)
Published in Muscle & nerve (01.08.2020)
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Poly(GR) and poly(GA) in cerebrospinal fluid as potential biomarkers for C9ORF72-ALS/FTD
Krishnan, Gopinath, Raitcheva, Denitza, Bartlett, Daniel, Prudencio, Mercedes, McKenna-Yasek, Diane M., Douthwright, Catherine, Oskarsson, Björn E., Ladha, Shafeeq, King, Oliver D., Barmada, Sami J., Miller, Timothy M., Bowser, Robert, Watts, Jonathan K., Petrucelli, Leonard, Brown, Robert H., Kankel, Mark W., Gao, Fen-Biao
Published in Nature communications (19.05.2022)
Published in Nature communications (19.05.2022)
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Unraveling the mechanisms involved in motor neuron degeneration in ALS
BRUIJN, Lucie I, MILLER, Timothy M, CLEVELAND, Don W
Published in Annual review of neuroscience (01.01.2004)
Published in Annual review of neuroscience (01.01.2004)
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