NLRP3 inflammasome signaling is activated by low-level lysosome disruption but inhibited by extensive lysosome disruption: roles for K+ efflux and Ca2+ influx
Katsnelson, Michael A, Lozada-Soto, Kristen M, Russo, Hana M, Miller, Barbara A, Dubyak, George R
Published in American Journal of Physiology: Cell Physiology (01.07.2016)
Published in American Journal of Physiology: Cell Physiology (01.07.2016)
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The human ion channel TRPM2 modulates migration and invasion in neuroblastoma through regulation of integrin expression
Bao, Lei, Festa, Fernanda, Hirschler-Laszkiewicz, Iwona, Keefer, Kerry, Wang, Hong-Gang, Cheung, Joseph Y, Miller, Barbara A
Published in Scientific reports (29.11.2022)
Published in Scientific reports (29.11.2022)
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Functional coupling of TRPM2 and extrasynaptic NMDARs exacerbates excitotoxicity in ischemic brain injury
Zong, Pengyu, Feng, Jianlin, Yue, Zhichao, Li, Yunfeng, Wu, Gongxiong, Sun, Baonan, He, Yanlin, Miller, Barbara, Yu, Albert S., Su, Zhongping, Xie, Jia, Mori, Yasuo, Hao, Bing, Yue, Lixia
Published in Neuron (Cambridge, Mass.) (15.06.2022)
Published in Neuron (Cambridge, Mass.) (15.06.2022)
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Targeted Inhibition of ULK1 Promotes Apoptosis and Suppresses Tumor Growth and Metastasis in Neuroblastoma
Dower, Christopher M, Bhat, Neema, Gebru, Melat T, Chen, Longgui, Wills, Carson A, Miller, Barbara A, Wang, Hong-Gang
Published in Molecular cancer therapeutics (01.11.2018)
Published in Molecular cancer therapeutics (01.11.2018)
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The human ion channel TRPM2 modulates neuroblastoma cell survival and mitochondrial function through Pyk2, CREB, and MCU activation
Hirschler-Laszkiewicz, Iwona, Chen, Shu-Jen, Bao, Lei, Wang, JuFang, Zhang, Xue-Qian, Shanmughapriya, Santhanam, Keefer, Kerry, Madesh, Muniswamy, Cheung, Joseph Y, Miller, Barbara A
Published in American Journal of Physiology: Cell Physiology (01.10.2018)
Published in American Journal of Physiology: Cell Physiology (01.10.2018)
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Technical outcomes of sentinel-lymph-node resection and conventional axillary-lymph-node dissection in patients with clinically node-negative breast cancer: results from the NSABP B-32 randomised phase III trial
Krag, David N, Prof, Anderson, Stewart J, Prof, Julian, Thomas B, Prof, Brown, Ann M, ScD, Harlow, Seth P, Prof, Ashikaga, Takamaru, Prof, Weaver, Donald L, Prof, Miller, Barbara J, MSN, Jalovec, Lynne M, MD, Frazier, Thomas G, Prof, Noyes, R Dirk, Prof, Robidoux, André, Prof, Scarth, Hugh MC, MD, Mammolito, Denise M, MD, McCready, David R, Prof, Mamounas, Eleftherios P, MD, Costantino, Joseph P, Prof, Wolmark, Norman, Prof
Published in The lancet oncology (01.10.2007)
Published in The lancet oncology (01.10.2007)
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Adjuvant Radiation Improves Recurrence-Free Survival and Overall Survival in Adrenocortical Carcinoma
Gharzai, Laila A, Green, Michael D, Griffith, Kent A, Else, Tobias, Mayo, Charles S, Hesseltine, Elizabeth, Spratt, Daniel E, Ben-Josef, Edgar, Sabolch, Aaron, Miller, Barbara S, Worden, Francis, Giordano, Thomas J, Hammer, Gary D, Jolly, Shruti
Published in The journal of clinical endocrinology and metabolism (01.09.2019)
Published in The journal of clinical endocrinology and metabolism (01.09.2019)
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Depletion of the Human Ion Channel TRPM2 in Neuroblastoma Demonstrates Its Key Role in Cell Survival through Modulation of Mitochondrial Reactive Oxygen Species and Bioenergetics
Bao, Lei, Chen, Shu-jen, Conrad, Kathleen, Keefer, Kerry, Abraham, Thomas, Lee, John P., Wang, JuFang, Zhang, Xue-Qian, Hirschler-Laszkiewicz, Iwona, Wang, Hong-Gang, Dovat, Sinisa, Gans, Brian, Madesh, Muniswamy, Cheung, Joseph Y., Miller, Barbara A.
Published in The Journal of biological chemistry (18.11.2016)
Published in The Journal of biological chemistry (18.11.2016)
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Glucocorticoids enhance the antileukemic activity of FLT3 inhibitors in FLT3-mutant acute myeloid leukemia
Gebru, Melat T., Atkinson, Jennifer M., Young, Megan M., Zhang, Lijun, Tang, Zhenyuan, Liu, Zhenqiu, Lu, Pinyi, Dower, Christopher M., Chen, Longgui, Annageldiyev, Charyguly, Sharma, Arati, Imamura Kawasawa, Yuka, Zhao, Zhongming, Miller, Barbara A., Claxton, David F., Wang, Hong-Gang
Published in Blood (27.08.2020)
Published in Blood (27.08.2020)
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The human ion channel TRPM2 modulates cell survival in neuroblastoma through E2F1 and FOXM1
Hirschler-Laszkiewicz, Iwona, Festa, Fernanda, Huang, Suming, Moldovan, George-Lucian, Nicolae, Claudia, Dhoonmoon, Ashna, Bao, Lei, Keefer, Kerry, Chen, Shu-Jen, Wang, Hong-Gang, Cheung, Joseph Y, Miller, Barbara A
Published in Scientific reports (15.04.2022)
Published in Scientific reports (15.04.2022)
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A Splice Variant of the Human Ion Channel TRPM2 Modulates Neuroblastoma Tumor Growth through Hypoxia-inducible Factor (HIF)-1/2α
Chen, Shu-jen, Hoffman, Nicholas E., Shanmughapriya, Santhanam, Bao, Lei, Keefer, Kerry, Conrad, Kathleen, Merali, Salim, Takahashi, Yoshinori, Abraham, Thomas, Hirschler-Laszkiewicz, Iwona, Wang, JuFang, Zhang, Xue-Qian, Song, Jianliang, Barrero, Carlos, Shi, Yuguang, Kawasawa, Yuka Imamura, Bayerl, Michael, Sun, Tianyu, Barbour, Mustafa, Wang, Hong-Gang, Madesh, Muniswamy, Cheung, Joseph Y., Miller, Barbara A.
Published in The Journal of biological chemistry (26.12.2014)
Published in The Journal of biological chemistry (26.12.2014)
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The Human Transient Receptor Potential Melastatin 2 Ion Channel Modulates ROS Through Nrf2
Bao, Lei, Festa, Fernanda, Freet, Christopher S, Lee, John P, Hirschler-Laszkiewicz, Iwona M, Chen, Shu-Jen, Keefer, Kerry A, Wang, Hong-Gang, Patterson, Andrew D, Cheung, Joseph Y, Miller, Barbara A
Published in Scientific reports (01.10.2019)
Published in Scientific reports (01.10.2019)
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Transient receptor potential ion channel TRPM2 promotes AML proliferation and survival through modulation of mitochondrial function, ROS, and autophagy
Chen, Shu-Jen, Bao, Lei, Keefer, Kerry, Shanmughapriya, Santhanam, Chen, Longgui, Lee, John, Wang, JuFang, Zhang, Xue-Qian, Hirschler-Laszkiewicz, Iwona, Merali, Salim, Merali, Carmen, Imamura, Yuka, Dovat, Sinisa, Madesh, Muniswamy, Cheung, Joseph Y, Wang, Hong-Gang, Miller, Barbara A
Published in Cell death & disease (20.04.2020)
Published in Cell death & disease (20.04.2020)
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