Effect of hydroxyl group configuration in hydroxyethylamine dipeptide isosteres on HIV protease inhibition. Evidence for multiple binding modes
Rich, Daniel H, Sun, Chong Qing, Prasad, J. V. N. Vara, Pathiasseril, Ahammadunny, Toth, Mihaly V, Marshall, Garland R, Clare, Michael, Mueller, Richard A, Houseman, Kathryn
Published in Journal of medicinal chemistry (01.03.1991)
Published in Journal of medicinal chemistry (01.03.1991)
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Use of Photoactivatable Peptide Substrates of Saccharomyces cerevisiae Myristoyl-CoA:Protein N-Myristoyltransferase (Nmt1p) to Characterize a Myristoyl-CoA-Nmt1p-Peptide Ternary Complex and to Provide Evidence for an Ordered Reaction Mechanism
Rudnick, D A, Rocque, W J, McWherter, C A, Toth, M V, Jackson-Machelski, E, Gordon, J I
Published in Proceedings of the National Academy of Sciences - PNAS (01.02.1993)
Published in Proceedings of the National Academy of Sciences - PNAS (01.02.1993)
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Journal Article
Structure of Complex of Synthetic HIV-1 Protease with a Substrate-Based Inhibitor at 2.3 Å Resolution
Miller, Maria, Schneider, Jens, Sathyanarayana, Bangalore K., Toth, Mihaly V., Marshall, Garland R., Clawson, Leigh, Selk, Linda, Stephen B. H. Kent, Wlodawer, Alexander
Published in Science (American Association for the Advancement of Science) (01.12.1989)
Published in Science (American Association for the Advancement of Science) (01.12.1989)
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Measurement of Specific Protease Activity Utilizing Fluorescence Polarization
Levine, Leanna M., Michener, Marshall L., Toth, Mihaly V., Holwerda, Barry C.
Published in Analytical biochemistry (05.04.1997)
Published in Analytical biochemistry (05.04.1997)
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Journal Article
Selective heterocyclic amidine inhibitors of human inducible nitric oxide synthase
Moormann, Alan E, Metz, Sue, Toth, Mihaly V, Moore, William M, Jerome, Gina, Kornmeier, Christine, Manning, Pamela, Hansen, Donald W, Pitzele, Barnett S, Webber, R.K
Published in Bioorganic & medicinal chemistry letters (08.10.2001)
Published in Bioorganic & medicinal chemistry letters (08.10.2001)
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Substituted 2-Iminopiperidines as Inhibitors of Human Nitric Oxide Synthase Isoforms
Webber, R. Keith, Metz, Suzanne, Moore, William M, Connor, Jane R, Currie, Mark G, Fok, Kam F, Hagen, Timothy J, Hansen, Donald W, Jerome, Gina M, Manning, Pamela T, Pitzele, Barnett S, Toth, Mihaly V, Trivedi, Mahima, Zupec, Mark E, Tjoeng, F. Siong
Published in Journal of medicinal chemistry (01.01.1998)
Published in Journal of medicinal chemistry (01.01.1998)
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Conformational mimicry. 3. Synthesis and incorporation of 1,5-disubstituted tetrazole dipeptide analogs into peptides with preservation of chiral integrity: bradykinin
Zabrocki, Janusz, Dunbar, James B, Marshall, Keith W, Toth, Mihaly V, Marshall, Garland R
Published in Journal of organic chemistry (01.01.1992)
Published in Journal of organic chemistry (01.01.1992)
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A simple, continuous fluorometric assay for HIV protease
Toth, M V, Marshall, G R
Published in International journal of peptide and protein research (01.12.1990)
Published in International journal of peptide and protein research (01.12.1990)
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Potent in Vitro and in Vivo Inhibitors of Platelet Aggregation Based Upon the Arg-Gly-Asp Sequence of Fibrinogen. (Aminobenzamidino)succinyl (ABAS) Series of Orally Active Fibrinogen Receptor Antagonists
Zablocki, Jeffery A, Rico, Joseph G, Garland, Robert B, Rogers, Thomas E, Williams, Kenneth, Schretzman, Lori A, Rao, Shashidhar A, Bovy, Philippe R, Tjoeng, Foe S
Published in Journal of medicinal chemistry (01.06.1995)
Published in Journal of medicinal chemistry (01.06.1995)
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Journal Article
Activity of two-chain recombinant human cytomegalovirus protease
Holwerda, B C, Wittwer, A J, Duffin, K L, Smith, C, Toth, M V, Carr, L S, Wiegand, R C, Bryant, M L
Published in The Journal of biological chemistry (14.10.1994)
Published in The Journal of biological chemistry (14.10.1994)
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Journal Article
A novel series of orally active antiplatelet agents
Zablocki, Jeffery A., Tjoeng, Foe S., Bovy, Philippe R., Miyano, Masateru, Garland, Robert B., Williams, Kenneth, Schretzman, Lori, Zupec, Mark E., Rico, Joseph G., Lindmark, Richard J., Toth, Mihaly V., McMackins, Dudley E., Adams, Steven P., Panzer-Knodle, Susan G., Nicholson, Nancy S., Taite, Beatrice B., Salyers, Anita K., King, Lucy W., Campion, James G., Feigen, Larry P.
Published in Bioorganic & medicinal chemistry (01.05.1995)
Published in Bioorganic & medicinal chemistry (01.05.1995)
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Syntheses of new conformationally constrained S-[2-[(1-iminoethyl)amino] ethyl]homocysteine derivatives as potential nitric oxide synthase inhibitors
Wang, Lijuan J., Grapperhaus, Margaret L., Pitzele, Barnett S., Hagen, Timothy J., Fok, Kam F., Scholten, Jeffrey A., Spangler, Dale P., Toth, Mihaly V., Jerome, Gina M., Moore, William M., Manning, Pamela T., Sikorski, James A.
Published in Heteroatom chemistry (2002)
Published in Heteroatom chemistry (2002)
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HIV-1 protease inhibitors: Ketomethylene isosteres with unusually high affinity compared with hydroxyethylene isostere analogs
Marinier, Aime, Toth, Mihaly V., Houseman, Kathryn, Mueller, Richard, Marshall, Garland R.
Published in Bioorganic & medicinal chemistry (01.09.1994)
Published in Bioorganic & medicinal chemistry (01.09.1994)
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Journal Article
The herpesvirus protease: mechanistic studies and discovery of inhibitors of the human cytomegalovirus protease
Flynn, D L, Becker, D P, Dilworth, V M, Highkin, M K, Hippenmeyer, P J, Houseman, K A, Levine, L M, Li, M, Moormann, A E, Rankin, A, Toth, M V, Villamil, C I, Wittwer, A J, Holwerda, B C
Published in Drug design and discovery (01.05.1997)
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Published in Drug design and discovery (01.05.1997)
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