Dysregulation of glutathione homeostasis in neurodegenerative diseases
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Upregulation of Glutaredoxin-1 Activates Microglia and Promotes Neurodegeneration: Implications for Parkinson's Disease
Gorelenkova Miller, Olga, Behring, Jessica Belle, Siedlak, Sandra L, Jiang, Sirui, Matsui, Reiko, Bachschmid, Markus M, Zhu, Xiongwei, Mieyal, John J
Published in Antioxidants & redox signaling (20.12.2016)
Published in Antioxidants & redox signaling (20.12.2016)
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Regulation of the Dimerization and Activity of SARS-CoV-2 Main Protease through Reversible Glutathionylation of Cysteine 300
Davis, David A, Bulut, Haydar, Shrestha, Prabha, Yaparla, Amulya, Jaeger, Hannah K, Hattori, Shin-ichiro, Wingfield, Paul T, Mieyal, John J, Mitsuya, Hiroaki, Yarchoan, Robert
Published in mBio (31.08.2021)
Published in mBio (31.08.2021)
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Deglutathionylation of 2-Cys Peroxiredoxin Is Specifically Catalyzed by Sulfiredoxin
Park, Ji Won, Mieyal, John J., Rhee, Sue Goo, Chock, P. Boon
Published in The Journal of biological chemistry (28.08.2009)
Published in The Journal of biological chemistry (28.08.2009)
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HSV infection induces production of ROS, which potentiate signaling from pattern recognition receptors: role for S-glutathionylation of TRAF3 and 6
Gonzalez-Dosal, Regina, Horan, Kristy A, Rahbek, Stine H, Ichijo, Hidenori, Chen, Zhijian J, Mieyal, John J, Hartmann, Rune, Paludan, Søren R
Published in PLoS pathogens (01.09.2011)
Published in PLoS pathogens (01.09.2011)
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Regulation of DJ‑1 by Glutaredoxin 1 in Vivo: Implications for Parkinson’s Disease
Johnson, William M, Golczak, Marcin, Choe, Kyonghwan, Curran, Pierce L, Miller, Olga Gorelenkova, Yao, Chen, Wang, Wenzhang, Lin, Jiusheng, Milkovic, Nicole M, Ray, Ajit, Ravindranath, Vijayalakshmi, Zhu, Xiongwei, Wilson, Mark A, Wilson-Delfosse, Amy L, Chen, Shu G, Mieyal, John J
Published in Biochemistry (Easton) (16.08.2016)
Published in Biochemistry (Easton) (16.08.2016)
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Kinetic and Mechanistic Characterization and Versatile Catalytic Properties of Mammalian Glutaredoxin 2: Implications for Intracellular Roles
Gallogly, Molly M, Starke, David W, Leonberg, Amanda K, Ospina, Susan M. English, Mieyal, John J
Published in Biochemistry (Easton) (21.10.2008)
Published in Biochemistry (Easton) (21.10.2008)
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Novel chloroacetamido compound CWR-J02 is an anti-inflammatory glutaredoxin-1 inhibitor
Gorelenkova Miller, Olga, Cole, Kyle S, Emerson, Corey C, Allimuthu, Dharmaraja, Golczak, Marcin, Stewart, Phoebe L, Weerapana, Eranthie, Adams, Drew J, Mieyal, John J
Published in PloS one (20.11.2017)
Published in PloS one (20.11.2017)
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Levodopa Activates Apoptosis Signaling Kinase 1 (ASK1) and Promotes Apoptosis in a Neuronal Model: Implications for the Treatment of Parkinson's Disease
Sabens Liedhegner, Elizabeth A, Steller, Kelly M, Mieyal, John J
Published in Chemical research in toxicology (17.10.2011)
Published in Chemical research in toxicology (17.10.2011)
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What is the functional significance of the unique location of glutaredoxin 1 (GRx1) in the intermembrane space of mitochondria?
Pai, Harish V, Starke, David W, Lesnefsky, Edward J, Hoppel, Charles L, Mieyal, John J
Published in Antioxidants & redox signaling (01.11.2007)
Published in Antioxidants & redox signaling (01.11.2007)
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Regulation by reversible S-glutathionylation: Molecular targets implicated in inflammatory diseases
Shelton, Melissa D. (Case Western Reserve University, and Louis Stokes Cleveland Veterans Affairs Medical Research Center, Cleveland, Ohio, USA), Mieyal, John J. (Case Western Reserve University, and Louis Stokes Cleveland Veterans Affairs Medical Research Center, Cleveland, Ohio, USA), E-mail: JJM5@case.edu
Published in Molecules and cells (31.05.2008)
Published in Molecules and cells (31.05.2008)
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Covalent Cross-Linking of Glutathione and Carnosine to Proteins by 4-Oxo-2-nonenal
Zhu, Xiaochun, Gallogly, Molly M, Mieyal, John J, Anderson, Vernon E, Sayre, Lawrence M
Published in Chemical research in toxicology (01.06.2009)
Published in Chemical research in toxicology (01.06.2009)
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Stable and Controllable RNA Interference: Investigating the Physiological Function of Glutathionylated Actin
Wang, Jun, Tekle, Ephrem, Oubrahim, Hammou, Mieyal, John J., Stadtman, Earl R., Chock, P. Boon
Published in Proceedings of the National Academy of Sciences - PNAS (29.04.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (29.04.2003)
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