Discovery and characterization of taspoglutide, a novel analogue of human glucagon-like peptide-1, engineered for sustained therapeutic activity in type 2 diabetes
Dong, J.Z, Shen, Y, Zhang, J, Tsomaia, N, Mierke, D.F, Taylor, J.E
Published in Diabetes, obesity & metabolism (2011)
Published in Diabetes, obesity & metabolism (2011)
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Photoaffinity Labeling of Mutant Neurokinin-1 Receptors Reveals Additional Structural Features of the Substance P/NK-1 Receptor Complex
Macdonald, Douglas, Mierke, Dale F, Li, Hanzhong, Pellegrini, Maria, Sachais, Bruce, Krause, James E, Leeman, Susan E, Boyd, Norman D
Published in Biochemistry (Easton) (27.02.2001)
Published in Biochemistry (Easton) (27.02.2001)
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New evidence for a membrane-bound pathway in hormone receptor binding
Moroder, Luis, Romano, Roberta, Guba, Wolfgang, Mierke, Dale F, Kessler, Horst, Delporte, Christine, Winand, Jacques, Christophe, Jean
Published in Biochemistry (Easton) (14.12.1993)
Published in Biochemistry (Easton) (14.12.1993)
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Journal Article
Structure-Based Optimization of Peptide Inhibitors of Mammalian Ribonucleotide Reductase
Pellegrini, Maria, Liehr, Sebastian, Fisher, Alison L, Laub, Paul B, Cooperman, Barry S, Mierke, Dale F
Published in Biochemistry (Easton) (10.10.2000)
Published in Biochemistry (Easton) (10.10.2000)
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Journal Article
Vancomycin: Conformational Consequences of the Sugar Substituent
Grdadolnik, Simona Golic, Pristovšek, Primoz, Mierke, Dale F
Published in Journal of medicinal chemistry (04.06.1998)
Published in Journal of medicinal chemistry (04.06.1998)
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Structural characterization of the parathyroid hormone receptor domains determinant for ligand binding
Mierke, D F, Mao, L, Pellegrini, M, Piserchio, A, Plati, J, Tsomaia, N
Published in Biochemical Society transactions (01.08.2007)
Published in Biochemical Society transactions (01.08.2007)
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Agonist Activity at the Kinin B1 Receptor: Structural Requirements of the Central Tetrapeptide
Rovero, Paolo, Pellegrini, Maria, Di Fenza, Armida, Meini, Stefania, Quartara, Laura, Maggi, Carlo A, Formaggio, Fernando, Toniolo, Claudio, Mierke, Dale F
Published in Journal of medicinal chemistry (18.01.2001)
Published in Journal of medicinal chemistry (18.01.2001)
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Journal Article
Conformational Studies of RS-66271, an Analog of Parathyroid Hormone-Related Protein with Pronounced Bone Anabolic Activity
Pellegrini, Maria, Bisello, Alessandro, Rosenblatt, Michael, Chorev, Michael, Mierke, Dale F
Published in Journal of medicinal chemistry (12.09.1997)
Published in Journal of medicinal chemistry (12.09.1997)
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Journal Article
The structure of Ro 09-0198 in different environments
Kessler, H, Mierke, D F, Saulitis, J, Seip, S, Steuernagel, S, Wein, T, Will, M
Published in Biopolymers (01.04.1992)
Published in Biopolymers (01.04.1992)
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NMR Determination of the Major Solution Conformation of a Peptoid Pentamer with Chiral Side Chains
Armand, Philippe, Kirshenbaum, Kent, Goldsmith, Richard A., Farr-Jones, Shauna, Barron, Annelise E., Kiet T. V. Truong, Dill, Ken A., Mierke, Dale F., Cohen, Fred E., Zuckermann, Ronald N., Bradley, Erin K.
Published in Proceedings of the National Academy of Sciences - PNAS (14.04.1998)
Published in Proceedings of the National Academy of Sciences - PNAS (14.04.1998)
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Journal Article
Parathyroid Hormone-Receptor Interactions Identified Directly by Photocross-linking and Molecular Modeling Studies
Bisello, Alessandro, Adams, Amy E., Mierke, Dale F., Pellegrini, Maria, Rosenblatt, Michael, Suva, Larry J., Chorev, Michael
Published in The Journal of biological chemistry (28.08.1998)
Published in The Journal of biological chemistry (28.08.1998)
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Comparison of the Conformation of Active and Nonactive Backbone Cyclic Analogs of Substance P as a Tool To Elucidate Features of the Bioactive Conformation: NMR and Molecular Dynamics in DMSO and Water
Grdadolnik, Simona Golic, Mierke, Dale F, Byk, Gerardo, Zeltser, Irena, Gilon, Chaim, Kessler, Horst
Published in Journal of medicinal chemistry (01.07.1994)
Published in Journal of medicinal chemistry (01.07.1994)
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Journal Article
Mapping the bimolecular interface of the parathyroid hormone (PTH)-PTH1 receptor complex: spatial proximity between Lys(27) (of the hormone principal binding domain) and leu(261) (of the first extracellular loop) of the human PTH1 receptor
Greenberg, Z, Bisello, A, Mierke, D F, Rosenblatt, M, Chorev, M
Published in Biochemistry (Easton) (18.07.2000)
Published in Biochemistry (Easton) (18.07.2000)
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Conformational analysis by NMR and distance geometry techniques of a peptide mimetic of the third helix of the Antennapedia homeodomain
Saviano, M., Isernia, C., Bassarello, C., Di Lello, P., Galdiero, S., Mierke, D.F., Benedetti, E., Pedone, C.
Published in The journal of peptide research (01.02.2005)
Published in The journal of peptide research (01.02.2005)
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