The discovery of a new antibody for BRIL-fused GPCR structure determination
Miyagi, Hikaru, Asada, Hidetsugu, Suzuki, Michihiko, Takahashi, Yuichi, Yasunaga, Mai, Suno, Chiyo, Iwata, So, Saito, Jun-ichi
Published in Scientific reports (15.07.2020)
Published in Scientific reports (15.07.2020)
Get full text
Journal Article
Development of Dihydrodibenzooxepine Peroxisome Proliferator-Activated Receptor (PPAR) Gamma Ligands of a Novel Binding Mode as Anticancer Agents: Effective Mimicry of Chiral Structures by Olefinic E/Z‑Isomers
Yamamoto, Keisuke, Tamura, Tomohiro, Henmi, Kazuki, Kuboyama, Takeshi, Yanagisawa, Arata, Matsubara, Masahiro, Takahashi, Yuichi, Suzuki, Michihiko, Saito, Jun-ichi, Ueno, Kimihisa, Shuto, Satoshi
Published in Journal of medicinal chemistry (21.11.2018)
Published in Journal of medicinal chemistry (21.11.2018)
Get full text
Journal Article
siRNA potency enhancement via chemical modifications of nucleotide bases at the 5'-end of the siRNA guide strand
Shinohara, Fumikazu, Oashi, Taiji, Harumoto, Toshimasa, Nishikawa, Tomoyuki, Takayama, Yuki, Miyagi, Hikaru, Takahashi, Yuichi, Nakajima, Takahiro, Sawada, Takashi, Koda, Yasuo, Makino, Asana, Sato, Atsuko, Hamaguchi, Kaori, Suzuki, Michihiko, Yamamoto, Junichiro, Tomari, Yukihide, Saito, Jun-Ichi
Published in RNA (Cambridge) (01.02.2021)
Published in RNA (Cambridge) (01.02.2021)
Get full text
Journal Article
Structural insight into an anti‐BRIL Fab as a G‐protein‐coupled receptor crystallization chaperone
Miyagi, Hikaru, Suzuki, Michihiko, Yasunaga, Mai, Asada, Hidetsugu, Iwata, So, Saito, Jun-ichi
Published in Acta crystallographica. Section D, Biological crystallography. (01.05.2023)
Published in Acta crystallographica. Section D, Biological crystallography. (01.05.2023)
Get full text
Journal Article
In Vitro Pharmacological Profile of KW-6356, a Novel Adenosine A2A Receptor Antagonist/Inverse Agonist
Ohno, Yutaro, Suzuki, Michihiko, Asada, Hidetsugu, Kanda, Tomoyuki, Saki, Mayumi, Miyagi, Hikaru, Yasunaga, Mai, Suno, Chiyo, Iwata, So, Saito, Jun-Ichi, Uchida, Shinichi
Published in Molecular pharmacology (01.06.2023)
Published in Molecular pharmacology (01.06.2023)
Get full text
Journal Article
Crystal structure of the GH-46 subclass III chitosanase from Bacillus circulans MH-K1 in complex with chitotetraose
Suzuki, Michihiko, Saito, Akihiro, Kobayashi, Mariko, Yokoyama, Tomofumi, Omiya, Shoko, Li, Jian, Sugita, Kei, Miki, Kunio, Saito, Jun-Ichi, Ando, Akikazu
Published in Biochimica et biophysica acta. General subjects (01.03.2024)
Published in Biochimica et biophysica acta. General subjects (01.03.2024)
Get full text
Journal Article
In Vitro Pharmacological Profile of KW-6356, a Novel Adenosine A 2A Receptor Antagonist/Inverse Agonist
Ohno, Yutaro, Suzuki, Michihiko, Asada, Hidetsugu, Kanda, Tomoyuki, Saki, Mayumi, Miyagi, Hikaru, Yasunaga, Mai, Suno, Chiyo, Iwata, So, Saito, Jun-Ichi, Uchida, Shinichi
Published in Molecular pharmacology (01.06.2023)
Published in Molecular pharmacology (01.06.2023)
Get full text
Journal Article
The novel potent TEAD inhibitor, K-975, inhibits YAP1/TAZ-TEAD protein-protein interactions and exerts an anti-tumor effect on malignant pleural mesothelioma
Kaneda, Ayumi, Seike, Toshihiro, Danjo, Tomohiro, Nakajima, Takahiro, Otsubo, Nobumasa, Yamaguchi, Daisuke, Tsuji, Yoshiro, Hamaguchi, Kaori, Yasunaga, Mai, Nishiya, Yoichi, Suzuki, Michihiko, Saito, Jun-Ichi, Yatsunami, Rie, Nakamura, Satoshi, Sekido, Yoshitaka, Mori, Kiyotoshi
Published in American journal of cancer research (01.01.2020)
Get full text
Published in American journal of cancer research (01.01.2020)
Journal Article
Development of a novel class of peroxisome proliferator-activated receptor (PPAR) gamma ligands as an anticancer agent with a unique binding mode based on a non-thiazolidinedione scaffold
Yamamoto, Keisuke, Tamura, Tomohiro, Nakamura, Rina, Hosoe, Shintaro, Matsubara, Masahiro, Nagata, Keiko, Kodaira, Hiroshi, Uemori, Takeshi, Takahashi, Yuichi, Suzuki, Michihiko, Saito, Jun-ichi, Ueno, Kimihisa, Shuto, Satoshi
Published in Bioorganic & medicinal chemistry (15.11.2019)
Published in Bioorganic & medicinal chemistry (15.11.2019)
Get full text
Journal Article
Abstract 3086: Discovery of a first-in-class TEAD inhibitor which directly inhibits YAP/TAZ-TEAD protein-protein interaction and shows a potent anti-tumor effect in malignant pleural mesothelioma
Kaneda, Ayumi, Seike, Toshihiro, Uemori, Takeshi, Myojo, Kensuke, Aida, Kensuke, Danjo, Tomohiro, Nakajima, Takahiro, Yamaguchi, Daisuke, Hamada, Tomoko, Tsuji, Yoshiro, Hamaguchi, Kaori, Yasunaga, Mai, Otsubo, Nobumasa, Onodera, Hideyuki, Nishiya, Yoichi, Suzuki, Michihiko, Saito, Junichi, Ishii, Toshihiko, Nakai, Ryuichiro
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Get full text
Journal Article
The dual pocket binding novel tankyrase inhibitor K-476 enhances the efficacy of immune checkpoint inhibitor by attracting CD8 + T cells to tumors
Kinosada, Haruka, Okada-Iwasaki, Ryoko, Kunieda, Kana, Suzuki-Imaizumi, Minami, Takahashi, Yuichi, Miyagi, Hikaru, Suzuki, Michihiko, Motosawa, Keiichi, Watanabe, Miwa, Mie, Motoya, Ishii, Toshihiko, Ishida, Hiroshi, Saito, Jun-Ichi, Nakai, Ryuichiro
Published in American journal of cancer research (2021)
Get full text
Published in American journal of cancer research (2021)
Journal Article
The structure of l-amino-acid ligase from Bacillus licheniformis
Suzuki, Michihiko, Takahashi, Yuichi, Noguchi, Atsushi, Arai, Toshinobu, Yagasaki, Makoto, Kino, Kuniki, Saito, Jun-ichi
Published in Acta crystallographica. Section D, Biological crystallography. (01.11.2012)
Published in Acta crystallographica. Section D, Biological crystallography. (01.11.2012)
Get full text
Journal Article
Micro CTD data logger reveals short-term excursions of Japanese sea bass from seawater to freshwater
Miyata, N, Mori, T, Kagehira, M, Miyazaki, N, Suzuki, M, Sato, K
Published in Aquatic biology (24.08.2016)
Published in Aquatic biology (24.08.2016)
Get full text
Journal Article
Anti-bril antibody
Saito, Junichi, Iwata, So, Suzuki, Michihiko, Miyagi, Hikaru, Asada, Hidetsugu
Year of Publication 03.10.2023
Get full text
Year of Publication 03.10.2023
Patent
A case of multiple organ failure induced by postoperative radiation therapy probably evoking oxidative stress
SOEJIMA, Akinori, ISHIZUKA, Shynji, SUZUKI, Michihiko, MINOSHIMA, Shinobu, NAKABAYASHI, Kimimasa, KITAMOTO, Kiyoshi, NAGASAWA, Toshihiko
Published in Nihon Jinzo Gakkai shi (1995)
Published in Nihon Jinzo Gakkai shi (1995)
Get full text
Journal Article