Antibody-Drug Conjugates Bearing Pyrrolobenzodiazepine or Tubulysin Payloads Are Immunomodulatory and Synergize with Multiple Immunotherapies
Rios-Doria, Jonathan, Harper, Jay, Rothstein, Raymond, Wetzel, Leslie, Chesebrough, Jon, Marrero, Allison, Chen, Cui, Strout, Patrick, Mulgrew, Kathy, McGlinchey, Kelly, Fleming, Ryan, Bezabeh, Binyam, Meekin, John, Stewart, David, Kennedy, Maureen, Martin, Philip, Buchanan, Andrew, Dimasi, Nazzareno, Michelotti, Emil, Hollingsworth, Robert
Published in Cancer research (Chicago, Ill.) (15.05.2017)
Published in Cancer research (Chicago, Ill.) (15.05.2017)
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Journal Article
A Monoclonal Antibody to ADAM17 Inhibits Tumor Growth by Inhibiting EGFR and Non-EGFR-Mediated Pathways
Rios-Doria, Jonathan, Sabol, Darrin, Chesebrough, Jon, Stewart, Dave, Xu, Linda, Tammali, Ravinder, Cheng, Li, Du, Qun, Schifferli, Kevin, Rothstein, Ray, Leow, Ching Ching, Heidbrink-Thompson, Jenny, Jin, Xiaofang, Gao, Changshou, Friedman, Jay, Wilkinson, Brandy, Damschroder, Melissa, Pierce, Andrew J, Hollingsworth, Robert E, Tice, David A, Michelotti, Emil F
Published in Molecular cancer therapeutics (01.07.2015)
Published in Molecular cancer therapeutics (01.07.2015)
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In Vivo Loss of Function Screening Reveals Carbonic Anhydrase IX as a Key Modulator of Tumor Initiating Potential in Primary Pancreatic Tumors
Pore, Nabendu, Jalla, Sanjoo, Liu, Zheng, Higgs, Brandon, Sorio, Claudio, Scarpa, Aldo, Hollingsworth, Robert, Tice, David A, Michelotti, Emil
Published in Neoplasia (New York, N.Y.) (01.06.2015)
Published in Neoplasia (New York, N.Y.) (01.06.2015)
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Journal Article
Cellular Nucleic Acid Binding Protein Regulates the CT Element of the Human c- myc Protooncogene
Michelotti, E F, Tomonaga, T, Krutzsch, H, Levens, D
Published in The Journal of biological chemistry (21.04.1995)
Published in The Journal of biological chemistry (21.04.1995)
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Journal Article
Specific down-regulation of an engineered human cyclin D1 promoter by a novel DNA-binding ligand in intact cells
Laurance, M E, Starr, D B, Michelotti, E F, Cheung, E, Gonzalez, C, Tam, A W, Deikman, J, Edwards, C A, Bardwell, A J
Published in Nucleic acids research (01.02.2001)
Published in Nucleic acids research (01.02.2001)
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Journal Article
Abstract 1166: ASCT2: A novel metabolic target for cancer therapy
Pore, Nabendu, King, Wanda, Lekstrom, Kristen, Wilson, Susan, Hollingsworth, Robert, Tice, David A., Michelotti, Emil
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Abstract 975: Monoclonal antibody targeting of ADAM17 is an effective treatment for metastatic colorectal cancer resulting in tumor growth control and reductions of cancer stem cells
Dosch, Joseph, Ziemke, Elizabeth, Welling, Theodore, Hardiman, Karin, Sebolt-Leopold, Juidth, Michelotti, Emil, Hollingsworth, Robert, Hurt, Elaine
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Abstract 1109: In vivo loss of function screening reveals carbonic anhydrase IX (CAIX) as a key modulator of tumor initiating potential in primary pancreatic tumors
Pore, Nabendu, Jalla, Sanjoo, Higgs, Brandon, Liu, Roger, Tice, David A., Hollingsworrth, Robert, Michelotti, Emil, Sorio, Claudio, Scarpa, Aldo
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Abstract 4596: Antibody-drug conjugates bearing pyrrolobenzodiazepine or tubulysin payloads alter the tumor immune microenvironment and synergize with multiple immunotherapies
Rios-Doria, Jonathan, Harper, Jay, Rothstein, Raymond, Wetzel, Leslie, Chesebrough, Jon, Marrero, Allison, Chen, Cui, Strout, Patrick, Mulgrew, Kathy, McGlinchey, Kelly, Fleming, Ryan, Bezabeh, Binyam, Meekin, John, Stewart, David, Kennedy, Maureen, Martin, Philip, Buchanan, Andrew, Dimasi, Nazzareno, Michelotti, Emil, Hollingsworth, Robert
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
InVivo Loss of Function Screening Reveals Carbonic Anhydrase IX as a Key Modulator of Tumor Initiating Potential in Primary Pancreatic Tumors12
Pore, Nabendu, Jalla, Sanjoo, Liu, Zheng, Higgs, Brandon, Sorio, Claudio, Scarpa, Aldo, Hollingsworth, Robert, Tice, David A., Michelotti, Emil
Published in Neoplasia (New York, N.Y.) (04.07.2015)
Published in Neoplasia (New York, N.Y.) (04.07.2015)
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Journal Article
InVivo Loss of Function Screening Reveals Carbonic Anhydrase IX as a Key Modulator of Tumor Initiating Potential in Primary Pancreatic Tumors
Pore, Nabendu, Jalla, Sanjoo, Liu, Zheng, Higgs, Brandon, Sorio, Claudio, Scarpa, Aldo, Hollingsworth, Robert, Tice, David A., Michelotti, Emil
Published in Neoplasia (New York, N.Y.) (01.06.2015)
Published in Neoplasia (New York, N.Y.) (01.06.2015)
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Journal Article
Abstract 30: Medi3622, a monoclonal antibody to ADAM17, inhibits tumor growth by inhibiting EGFR- and non-EGFR-mediated pathways
Sabol, Darrin, RiosDoria, Jonathan, Chesebrough, Jon, Stewart, David, Schifferli, Kevin, Rothstein, Raymond, Leow, Ching Ching, Heidbrink-Thompson, Jenny, Cheng, Li, Du, Qun, Xu, Linda, Jin, Xiaofang, Tammali, Ravinder, Gao, Chanshou, Friedman, Jay, Wilkinson, Brandy, Damschroder, Melissa, Pierce, Andrew, Patnaik, MunMun, Zeng, Rong, Wu, Yuling, Spitz, Susan, Robbie, Gabriel, Roskos, Lorin, Hollingsworth, Robert, Tice, David, Michelotti, Emil
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
ASCT2에 특이적인 결합 분자 및 이의 용도
TICE DAVID A, CHANG CHIEN YING, HOLLINGSWORTH ROBERT E, YAO NAI SHUN, HURT ELAINE M, BORROK III MARTIN J, CHOWDHURY PARTHA S, PORE NABENDU, MICHELOTTI EMIL F
Year of Publication 12.07.2019
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Year of Publication 12.07.2019
Patent
ASCT2에 특이적인 결합 분자 및 이의 용도
TICE DAVID A, CHOWDHURY PARTHA, CHANG CHIEN YING, HOLLINGSWORTH ROBERT E, PORE NABENDU, BORROK MARTIN J. III, MICHELOTTI EMIL F
Year of Publication 02.07.2018
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Year of Publication 02.07.2018
Patent
Heterogeneous nuclear ribonucleoprotein K is a transcription factor
Michelotti, Emil F., Michelotti, Gregory A., Aronsohn, Andrew I., Levens, David
Published in Molecular and Cellular Biology (01.05.1996)
Published in Molecular and Cellular Biology (01.05.1996)
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Journal Article
Multiple single-stranded cis elements are associated with activated chromatin of the human c-myc gene in vivo
Michelotti, Gregory A., Michelotti, Emil F., Pullner, Andrea, Duncan, Robert C., Eick, Dirk, Levens, David
Published in Molecular and Cellular Biology (01.06.1996)
Published in Molecular and Cellular Biology (01.06.1996)
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