Implementing Continuous Manufacturing for the Final Methylation Step in the AMG 397 Process to Deliver Key Quality Attributes
Tom, Janine K, Achmatowicz, Michal M, Beaver, Matthew G, Colyer, John, Ericson, Ari, Hwang, Tsang-Lin, Jiao, Nancy, Langille, Neil F, Liu, Min, Lovette, Michael A, Sangodkar, Rahul P, Sharvan Kumar, Srividya, Spada, Simone, Perera, Damith, Sheeran, Jillian, Campbell, Kiersten, Doherty, Timothy, Ford, David D, Fang, Yuan-Qing, Rossi, Emiliano, Santoni, Gabriella, Cui, Sheng, Walker, Shawn D
Published in Organic process research & development (19.03.2021)
Published in Organic process research & development (19.03.2021)
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Journal Article
Palladium-Catalyzed Chemoselective Monoarylation of Hydrazides for the Synthesis of [1,2,4]Triazolo[4,3-a]pyridines
Reichelt, Andreas, Falsey, James R, Rzasa, Robert M, Thiel, Oliver R, Achmatowicz, Michal M, Larsen, Robert D, Zhang, Dawei
Published in Organic letters (19.02.2010)
Published in Organic letters (19.02.2010)
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Journal Article
Hydrolysis of Phosphoryl Trichloride (POCl3): Characterization, in Situ Detection, and Safe Quenching of Energetic Metastable Intermediates
Achmatowicz, Michał M, Thiel, Oliver R, Colyer, John T, Hu, Jack, Elipe, Maria Victoria Silva, Tomaskevitch, Joe, Tedrow, Jason S, Larsen, Robert D
Published in Organic process research & development (19.11.2010)
Published in Organic process research & development (19.11.2010)
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Journal Article
Telescoped Process to Manufacture 6,6,6-Trifluorofucose via Diastereoselective Transfer Hydrogenation: Scalable Access to an Inhibitor of Fucosylation Utilized in Monoclonal Antibody Production
Achmatowicz, Michal M, Allen, John G, Bio, Matthew M, Bartberger, Michael D, Borths, Christopher J, Colyer, John T, Crockett, Richard D, Hwang, Tsang-Lin, Koek, Jan. N, Osgood, Stephen A, Roberts, Scott W, Swietlow, Aleksander, Thiel, Oliver R, Caille, Seb
Published in Journal of organic chemistry (03.06.2016)
Published in Journal of organic chemistry (03.06.2016)
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Journal Article
Palladium-Catalyzed Coupling of Aldehyde-Derived Hydrazones: Practical Synthesis of Triazolopyridines and Related Heterocycles
Thiel, Oliver R., Achmatowicz, Michal M., Reichelt, Andreas, Larsen, Robert D.
Published in Angewandte Chemie International Edition (02.11.2010)
Published in Angewandte Chemie International Edition (02.11.2010)
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Journal Article
Practical Synthesis of a p38 MAP Kinase Inhibitor
Achmatowicz, Michał, Thiel, Oliver R, Wheeler, Philip, Bernard, Charles, Huang, Jinkun, Larsen, Robert D, Faul, Margaret M
Published in Journal of organic chemistry (16.01.2009)
Published in Journal of organic chemistry (16.01.2009)
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Journal Article
Development of a Practical Synthesis of a p38 MAP Kinase Inhibitor
Thiel, Oliver R, Achmatowicz, Michal, Bernard, Charles, Wheeler, Philip, Savarin, Cecile, Correll, Tiffany L, Kasparian, Annie, Allgeier, Alan, Bartberger, Michael D, Tan, Helming, Larsen, Robert D
Published in Organic process research & development (20.03.2009)
Published in Organic process research & development (20.03.2009)
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Journal Article
A simple synthesis of chiral macrocyclic tetraamides derived from α-amino acids
Zieliński, Tomasz, Achmatowicz, Michał, Jurczak, Janusz
Published in Tetrahedron: asymmetry (20.09.2002)
Published in Tetrahedron: asymmetry (20.09.2002)
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Journal Article
Scalable Atroposelective Synthesis of MRTX1719: An Inhibitor of the PRMT5/MTA Complex
Achmatowicz, Michal, Scattolin, Thomas, Snead, David R., Paymode, Dinesh J., Roshandel, Sahar, Xie, Chen, Chen, Guihui, Chen, Cheng-yi
Published in Organic process research & development (19.05.2023)
Published in Organic process research & development (19.05.2023)
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Journal Article
Development of Adagrasib’s Commercial Manufacturing Route
Snead, David R., Gan, Yonghong, Scattolin, Thomas, Paymode, Dinesh J., Achmatowicz, Michal, Rudisill, Duane E., Vidal, Ephraim S., Gharbaoui, Tawfik, Roberts, Phil, Yang, Jianbo, Shi, Zhangbing, Liu, Wei, Bolger, Joshua, Qiao, Zhen, Chen, Cheng-yi
Published in Organic process research & development (17.03.2023)
Published in Organic process research & development (17.03.2023)
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Journal Article
METHOD OF CONJUGATION OF CYS-MAB
DANTE ROMANINI, BRADLEY J HERBERICH, MICHAL ACHMATOWICZ, JAMES R FALSEY, OLIVER R THIEL
Year of Publication 10.07.2024
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Year of Publication 10.07.2024
Patent
Titelbild: Palladium-Catalyzed Coupling of Aldehyde-Derived Hydrazones: Practical Synthesis of Triazolopyridines and Related Heterocycles (Angew. Chem. 45/2010)
Thiel, Oliver R., Achmatowicz, Michal M., Reichelt, Andreas, Larsen, Robert D.
Published in Angewandte Chemie (02.11.2010)
Published in Angewandte Chemie (02.11.2010)
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Journal Article
The Simple Synthesis of Chiral Polyazaoxacoronands Derived from α-Amino Acids
Achmatowicz, Michal, Szczepańska, Agnieszka, Gryko, Daniel T., Salański, Piotr, Jurczak, Janusz
Published in Supramolecular chemistry (01.09.2000)
Published in Supramolecular chemistry (01.09.2000)
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Journal Article