Discovery of ABT-267, a Pan-Genotypic Inhibitor of HCV NS5A
DeGoey, David A., Randolph, John T., Liu, Dachun, Pratt, John, Hutchins, Charles, Donner, Pamela, Krueger, A. Chris, Matulenko, Mark, Patel, Sachin, Motter, Christopher E., Nelson, Lissa, Keddy, Ryan, Tufano, Michael, Caspi, Daniel D., Krishnan, Preethi, Mistry, Neeta, Koev, Gennadiy, Reisch, Thomas J., Mondal, Rubina, Pilot-Matias, Tami, Gao, Yi, Beno, David W. A., Maring, Clarence J., Molla, Akhter, Dumas, Emily, Campbell, Andrew, Williams, Laura, Collins, Christine, Wagner, Rolf, Kati, Warren M.
Published in Journal of medicinal chemistry (13.03.2014)
Published in Journal of medicinal chemistry (13.03.2014)
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Discovery of pyrido[2,3-d]pyrimidine-based inhibitors of HCV NS5A
DeGoey, David A., Betebenner, David A., Grampovnik, David J., Liu, Dachun, Pratt, John K., Tufano, Michael D., He, Wenping, Krishnan, Preethi, Pilot-Matias, Tami J., Marsh, Kennan C., Molla, Akhteruzzaman, Kempf, Dale J., Maring, Clarence J.
Published in Bioorganic & medicinal chemistry letters (15.06.2013)
Published in Bioorganic & medicinal chemistry letters (15.06.2013)
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Synthesis and Biological Characterization of Aryl Uracil Inhibitors of Hepatitis C Virus NS5B Polymerase: Discovery of ABT-072, a trans-Stilbene Analog with Good Oral Bioavailability
Randolph, John T, Krueger, A. Chris, Donner, Pamela L, Pratt, John K, Liu, Dachun, Motter, Christopher E, Rockway, Todd W, Tufano, Michael D, Wagner, Rolf, Lim, Hock B, Beyer, Jill M, Mondal, Rubina, Panchal, Neeta S, Colletti, Lynn, Liu, Yaya, Koev, Gennadiy, Kati, Warren M, Hernandez, Lisa E, Beno, David W. A, Longenecker, Kenton L, Stewart, Kent D, Dumas, Emily O, Molla, Akhteruzzaman, Maring, Clarence J
Published in Journal of medicinal chemistry (08.02.2018)
Published in Journal of medicinal chemistry (08.02.2018)
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Novel Hepatitis C virus replicon inhibitors: Synthesis and structure–activity relationships of fused pyrimidine derivatives
Chris Krueger, A., Madigan, Darold L., Beno, David W., Betebenner, David A., Carrick, Robert, Green, Brian E., He, Wenping, Liu, Dachun, Maring, Clarence J., McDaniel, Keith F., Mo, Hongmei, Molla, Akhteruzzaman, Motter, Christopher E., Pilot-Matias, Tami J., Tufano, Michael D., Kempf, Dale J.
Published in Bioorganic & medicinal chemistry letters (15.03.2012)
Published in Bioorganic & medicinal chemistry letters (15.03.2012)
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Journal Article
Boc-CCK-4 derivatives containing side-chain ureas as potent and selective CCK-A receptor agonists
Shiosaki, Kazumi, Lin, Chun Wel, Kopecka, Hana, Tufano, Michael D, Bianchi, Bruce R, Miller, Thomas R, Witte, David G, Nadzan, Alex M
Published in Journal of medicinal chemistry (01.09.1991)
Published in Journal of medicinal chemistry (01.09.1991)
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Novel methodology for the synthesis of trans-alkene dipeptide isosteres
Shue, Youe Kong, Carrera, George M, Tufano, Michael D, Nadzan, Alex M
Published in Journal of organic chemistry (01.03.1991)
Published in Journal of organic chemistry (01.03.1991)
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Synthesis and biological activity of CCK heptapeptide analogs. Effects of conformational constraints and standard modifications on receptor subtype selectivity, functional activity in vitro, and appetite suppression in vivo
Holladay, Mark W, Bennett, Michael J, Tufano, Michael D, Lin, C. W, Asin, Karen E, Witte, David G, Miller, Thomas R, Bianchi, Bruce R, Nikkel, A. L
Published in Journal of medicinal chemistry (01.08.1992)
Published in Journal of medicinal chemistry (01.08.1992)
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Novel Asp32-Replacement Tetrapeptide Analogs as Potent and Selective CCK-A Agonists
Elliott, Richard L, Kopecka, Hana, Tufano, Michael D, Shue, Youe-Kong, Gauri, Andre J, Lin, Chun-Wel, Bianchi, Bruce R, Miller, Thomas R, Witte, David G
Published in Journal of medicinal chemistry (01.05.1994)
Published in Journal of medicinal chemistry (01.05.1994)
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Novel Inhibitors of Erm Methyltransferases from NMR and Parallel Synthesis
Hajduk, Philip J, Dinges, Jürgen, Schkeryantz, Jeffrey M, Janowick, David, Kaminski, Michele, Tufano, Michael, Augeri, David J, Petros, Andrew, Nienaber, Vicki, Zhong, Ping, Hammond, Rachel, Coen, Michael, Beutel, Bruce, Katz, Leonard, Fesik, Stephen W
Published in Journal of medicinal chemistry (23.09.1999)
Published in Journal of medicinal chemistry (23.09.1999)
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Synthesis and Structure−Activity Relationships of 2-Pyridones: A Novel Series of Potent DNA Gyrase Inhibitors as Antibacterial Agents
Li, Qun, Chu, Daniel T. W, Claiborne, Akiyo, Cooper, Curt S, Lee, Cheuk M, Raye, Kathleen, Berst, Kristine B, Donner, Pamela, Wang, Weibo, Hasvold, Lisa, Fung, Anthony, Ma, Zhenkun, Tufano, Michael, Flamm, Robert, Shen, Linus L, Baranowski, John, Nilius, Angela, Alder, Jeff, Meulbroek, Jonathan, Marsh, Kennan, Crowell, DeAnne, Hui, Yuhua, Seif, Louis, Melcher, Laura M, Henry, Rodger, Spanton, Steven, Faghih, Ramin, Klein, Larry L, Tanaka, S. Ken, Plattner, Jacob J
Published in Journal of medicinal chemistry (02.08.1996)
Published in Journal of medicinal chemistry (02.08.1996)
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Novel inhibitors of bacterial protein synthesis: structure–activity relationships for 1,8-naphthyridine derivatives incorporating position 3 and 4 variants
Clark, Richard F., Wang, Sanyi, Ma, Zhenkun, Weitzberg, Moshe, Motter, Christopher, Tufano, Michael, Wagner, Rolf, Gu, Yu-Gui, Dandliker, Peter J., Lerner, Claude G., Chovan, Linda E., Cai, Yingna, Black-Schaefer, Candace L., Lynch, Linda, Kalvin, Douglas, Nilius, Angela M., Pratt, Steve D., Soni, Niru, Zhang, Tianyuan, Zhang, Xiaolin, Beutel, Bruce A.
Published in Bioorganic & medicinal chemistry letters (21.06.2004)
Published in Bioorganic & medicinal chemistry letters (21.06.2004)
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Journal Article
Synthesis and antibacterial activity of novel 6-O-substituted erythromycin A derivatives
CLARK, R. F, ZHENKUN MA, YAT SUN OR, SANYI WANG, GRIESGRABER, G, TUFANO, M, HONG YONG, LEPING LI, XIAOLIN ZHANG, NILIUS, A. M, CHU, D. T. W
Published in Bioorganic & medicinal chemistry letters (17.04.2000)
Published in Bioorganic & medicinal chemistry letters (17.04.2000)
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Automating test driven development with converters
SWIATKOWSKI ANDREW, TUFANO, MICHAEL, CLEMENT CHRISTOPHER B, DENG, SEN, K, SUNDARESAN NARAYANAN
Year of Publication 28.05.2024
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Year of Publication 28.05.2024
Patent
Anti-Viral Compounds
Sarris, Kathy, Wagaw, Seble H, Hutchins, Charles W, Carroll, William A, Li, Wenke, Randolph, John T, Jinkerson, Tammie K, Patel, Sachin V, Califano, Jean-Christophe C, Krueger, Allan C, Matulenko, Mark A, Betebenner, David A, Liu, Dachun, Tufano, Michael D, Kati, Warren M, Keddy, Ryan G, Flentge, Charles A, Maring, Clarence J, Bellizzi, Mary E, Pratt, John K, Hutchinson, Douglas K, Wagner, Rolf, Caspi, Daniel D, Rockway, Todd W, Donner, Pamela L, DeGoey, David A, Motter, Christopher E, Gao, Yi, Woller, Kevin R, Nelson, Lissa T
Year of Publication 14.09.2023
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Year of Publication 14.09.2023
Patent
Synthesis and structure-activity relationships of 2-pyridones: II. 8-(Fluoro-substituted pyrrolidinyl)-2-pyridones as antibacterial agents
Li, Qun, Wang, Weibo, Berst, Kristine B., Claiborne, Akiyo, Hasvold, Lisa, Raye, Kathleen, Tufano, Michael, Nilius, Angela, Shen, Linus L., Flamm, Robert, Alder, Jeff, Marsh, Kennan, Crowell, DeAnne, Chu, Daniel T.W., Plattner, Jacob J.
Published in Bioorganic & medicinal chemistry letters (04.08.1998)
Published in Bioorganic & medicinal chemistry letters (04.08.1998)
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