A DLL3-targeted antibody-drug conjugate eradicates high-grade pulmonary neuroendocrine tumor-initiating cells in vivo
Saunders, Laura R, Bankovich, Alexander J, Anderson, Wade C, Aujay, Monette A, Bheddah, Sheila, Black, KristenAnn, Desai, Radhika, Escarpe, Paul A, Hampl, Johannes, Laysang, Amy, Liu, David, Lopez-Molina, Javier, Milton, Milly, Park, Albert, Pysz, Marybeth A, Shao, Hui, Slingerland, Brian, Torgov, Michael, Williams, Samuel A, Foord, Orit, Howard, Philip, Jassem, Jacek, Badzio, Andrzej, Czapiewski, Piotr, Harpole, David H, Dowlati, Afshin, Massion, Pierre P, Travis, William D, Pietanza, M Catherine, Poirier, J T, Rudin, Charles M, Stull, Robert A, Dylla, Scott J
Published in Science translational medicine (26.08.2015)
Published in Science translational medicine (26.08.2015)
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Development of potent monoclonal antibody auristatin conjugates for cancer therapy
Senter, Peter D, Doronina, Svetlana O, Toki, Brian E, Torgov, Michael Y, Mendelsohn, Brian A, Cerveny, Charles G, Chace, Dana F, DeBlanc, Ron L, Gearing, R Patrick, Bovee, Tim D, Siegall, Clay B, Francisco, Joseph A, Wahl, Alan F, Meyer, Damon L
Published in Nature biotechnology (01.07.2003)
Published in Nature biotechnology (01.07.2003)
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Reduction−Alkylation Strategies for the Modification of Specific Monoclonal Antibody Disulfides
Sun, Michael M. C, Beam, Kevin S, Cerveny, Charles G, Hamblett, Kevin J, Blackmore, Richard S, Torgov, Michael Y, Handley, Felicia G. M, Ihle, Nathan C, Senter, Peter D, Alley, Stephen C
Published in Bioconjugate chemistry (01.09.2005)
Published in Bioconjugate chemistry (01.09.2005)
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Potent cytotoxicity of an auristatin-containing antibody-drug conjugate targeting melanoma cells expressing melanotransferrin/p97
Smith, Leia M, Nesterova, Albina, Alley, Stephen C, Torgov, Michael Y, Carter, Paul J
Published in Molecular cancer therapeutics (01.06.2006)
Published in Molecular cancer therapeutics (01.06.2006)
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Treatment parameters modulating regression of human melanoma xenografts by an antibody-drug conjugate (CR011-vcMMAE) targeting GPNMB
POLLACK, Vincent A, ALVAREZ, Enrique, HAHNE, William F, SENTER, Peter D, JEFFERS, Michael E, LICHENSTEIN, Henri S, LAROCHELLE, William J, KAM FAI TSE, TORGOV, Michael Y, SAM XIE, SHENOY, Suresh G, MACDOUGALL, John R, ARROL, Sharon, HAIHONG ZHONG, GERWIEN, Robert W
Published in Cancer chemotherapy and pharmacology (01.08.2007)
Published in Cancer chemotherapy and pharmacology (01.08.2007)
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Design, Synthesis, and in Vitro Evaluation of Dipeptide-Based Antibody Minor Groove Binder Conjugates
Jeffrey, Scott C, Torgov, Michael Y, Andreyka, Jamie B, Boddington, Laura, Cerveny, Charles G, Denny, William A, Gordon, Kristine A, Gustin, Darin, Haugen, Jennifer, Kline, Toni, Nguyen, Minh T, Senter, Peter D
Published in Journal of medicinal chemistry (10.03.2005)
Published in Journal of medicinal chemistry (10.03.2005)
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Novel Antitumor Prodrugs Designed for Activation by Matrix Metalloproteinases-2 and -9
Kline, Toni, Torgov, Michael Y, Mendelsohn, Brian A, Cerveny, Charles G, Senter, Peter D
Published in Molecular pharmaceutics (12.01.2004)
Published in Molecular pharmaceutics (12.01.2004)
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1485: Development of GLUT-1 targeted boron carriers for Boron Neutron Capture Therapy (BNCT)
Martin, Tioga J., Raitano, Art, Dlamini, Samkeliso, Zhang, Chunying, Capo, Linnette, Ikeura, Maki, Morrison, Karen, Malinao, Maria Christina, Quintana, Jason, Morrison, Kendall, Torgov, Michael
Published in Radiotherapy and oncology (01.05.2024)
Published in Radiotherapy and oncology (01.05.2024)
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Boronotyrosine, a Borylated Amino Acid Mimetic with Enhanced Solubility, Tumor Boron Delivery, and Retention for the Re-emerging Boron Neutron Capture Therapy Field
Raitano, Arthur, Martin, Tioga, Zhang, Chunying, Malinao, Maria-Christina, Capo, Linnette, Ikeura, Maki, Carroll, Rebecca, Quintana, Jason C., Dlamini, Samkeliso, Kulenovic, Leila, Jahanshir, Eva, Kang, Sohye, Morrison, Karen, Torgov, Michael, Morrison, Kendall
Published in Journal of medicinal chemistry (12.10.2023)
Published in Journal of medicinal chemistry (12.10.2023)
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First-in-man study of the PSMA Minibody IR800-IAB2M for molecularly targeted intraoperative fluorescence guidance during radical prostatectomy
Hamdy, Freddie C., Lamb, Alastair D., Tullis, Iain D. C., Verrill, Clare, Rombach, Ines, Rao, Srinivasa R., Colling, Richard, Barber, Paul R., Volpi, Davide, Barbera-Martin, Luis, Lopez, J Francisco, Omer, Altan, Hewitt, Aimi, Lovell, Shelagh, Niederer, Jane, Lambert, Adam, Snoeck, Joke, Thomson, Claire, Leslie, Tom, Bryant, Richard J., Mascioni, Alessandro, Jia, Fang, Torgov, Michael, Wilson, Ian, Gudas, Jean, Wu, Anna M., Olafsen, Tove, Vojnovic, Borivoj
Published in European journal of nuclear medicine and molecular imaging (01.08.2024)
Published in European journal of nuclear medicine and molecular imaging (01.08.2024)
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Abstract 1129: Monitoring intratumoral CD8 T cell infiltrates in human stem cell engrafted mice during single agent and combination immunotherapy with T cell bispecific antibodies using the human PET-tracer 89Zr-Df-IAB22M2C
Griessinger, Christoph M., Mascioni, Alessandro, Jia, Fang, Torgov, Michael, Nayak, Tapan, Mohan, Preethi Latha Bhavani, Nicolini, Valeria G., Sam, Johannes, Claus, Christina, Ferrara-Koller, Claudia, Bacac, Marina, Umana, Pablo, Wilson, Ian, Klein, Christian, Tessier, Jean J.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Cerenkov Luminescence Imaging as a Modality to Evaluate Antibody-Based PET Radiotracers
D'Souza, Jimson W, Hensley, Harvey, Doss, Mohan, Beigarten, Charles, Torgov, Michael, Olafsen, Tove, Yu, Jian Q, Robinson, Matthew K
Published in Journal of Nuclear Medicine (01.01.2017)
Published in Journal of Nuclear Medicine (01.01.2017)
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ANTIBODY-DRUG CONJUGATES (ADC) THAT BIND TO 191P4D12 PROTEIN
MORRISON KAREN JANE MEYRICK, GUDAS JEAN, MORRISON ROBERT KENDALL, AN ZILI, JAKOBOVITS AYA, DAULET SATPAEV, MICHAEL TORGOV
Year of Publication 19.12.2023
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Year of Publication 19.12.2023
Patent
First in Human Phase I Imaging Study With 89Zr-IAB22M2C Anti CD8 Minibody in Patients with Solid Tumors
Pandit-Taskar, Neeta, Postow, Micheal, O'Donoghue, Joseph, Harding, James, Ziolkowska, Martha, Lyashchenko, Serge, Lewis, Jason, Wu, Anna, Le, William, Gudas, Jean, Korn, Ronald, Torgov, Michael, Wolchok, Jedd, Weber, Wolfgang
Published in The Journal of nuclear medicine (1978) (01.05.2018)
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Published in The Journal of nuclear medicine (1978) (01.05.2018)
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The PET-tracer 89Zr-Df-IAB22M2C enables monitoring of intratumoral CD8 T cell infiltrates in tumor-bearing humanized mice after T cell bispecific antibody treatment
Griessinger, Christoph M, Olafsen, Tove, Mascioni, Alessandro, Jiang, Ziyue Karen, Zamilpa, Charles, Jia, Fang, Torgov, Michael, Romero, Jason M, Marchioni, Filippo, Satpayev, Daulet, Lee, Chenyu, Zhang, Green, Nayak, Tapan K, Pincha, Mudita, Amann, Maria, Mohan, Preethi Latha Bhavani, Richard, Marine, Nicolini, Valeria G, Sam, Johannes, Claus, Christina, Ferrara, Claudia, Brünker, Peter, Bacac, Marina, Umana, Pablo, Rüttinger, Dominik, Wilson, Ian A, Gudas, Jean, Klein, Christian, Tessier, Jean J L
Published in Cancer research (Chicago, Ill.) (01.07.2020)
Published in Cancer research (Chicago, Ill.) (01.07.2020)
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Abstract LB-188: Sensitivity of 89Zr-labeled anti-CD8 minibody for PET imaging of infiltrating CD8+ T cells
Olafsen, Tove, Jiang, Ziyue Karen, Romero, Jason, Zamilpa, Charles, Marchioni, Filippo, Zhang, Green, Torgov, Michael, Satpayev, Daulet, Gudas, Jean M.
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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