A decision algorithm to promote outpatient antimicrobial stewardship for uncomplicated urinary tract infection
Kanjilal, Sanjat, Oberst, Michael, Boominathan, Sooraj, Zhou, Helen, Hooper, David C, Sontag, David
Published in Science translational medicine (04.11.2020)
Published in Science translational medicine (04.11.2020)
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Resistance to Durvalumab and Durvalumab plus Tremelimumab Is Associated with Functional STK11 Mutations in Patients with Non-Small Cell Lung Cancer and Is Reversed by STAT3 Knockdown
Pore, Nabendu, Wu, Song, Standifer, Nathan, Jure-Kunkel, Maria, de Los Reyes, Melissa, Shrestha, Yashaswi, Halpin, Rebecca, Rothstein, Raymond, Mulgrew, Kathy, Blackmore, Stephen, Martin, Philip, Meekin, 3rd, John, Griffin, Matthew, Bisha, Ina, Proia, Theresa A, Miragaia, Ricardo J, Herbst, Ronald, Gupta, Ashok, Abdullah, Shaad E, Raja, Rajiv, Frigault, Melanie M, Barrett, J Carl, Dennis, Phillip A, Ascierto, Maria Libera, Oberst, Michael D
Published in Cancer discovery (01.11.2021)
Published in Cancer discovery (01.11.2021)
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The role of Fc gamma receptors in the activity of immunomodulatory antibodies for cancer
Stewart, Ross, Hammond, Scott A, Oberst, Michael, Wilkinson, Robert W
Published in Journal for Immunotherapy of Cancer (19.08.2014)
Published in Journal for Immunotherapy of Cancer (19.08.2014)
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Book Review
The ubiquitin peptidase UCHL1 induces G0/G1 cell cycle arrest and apoptosis through stabilizing p53 and is frequently silenced in breast cancer
Xiang, Tingxiu, Li, Lili, Yin, Xuedong, Yuan, Chenfu, Tan, Cui, Su, Xianwei, Xiong, Lei, Putti, Thomas C, Oberst, Michael, Kelly, Kathleen, Ren, Guosheng, Tao, Qian
Published in PloS one (18.01.2012)
Published in PloS one (18.01.2012)
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HER2-targeted antibody-drug conjugate induces host immunity against cancer stem cells
Xia, Leiming, Wen, Lu, Qin, You, Dobson, Hannah E., Zhang, Tao, Comer, Frank I., Hinrichs, Mary Jane, Oberst, Michael D., Coats, Steven R., Chang, Alfred E., Liu, Yuanyuan, Bao, Yangyi, Dai, Fu, Wicha, Max S., Li, Qiao
Published in Cell chemical biology (20.05.2021)
Published in Cell chemical biology (20.05.2021)
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Inhibition of insulin-like growth factors increases production of CXCL9/10 by macrophages and fibroblasts and facilitates CD8 + cytotoxic T cell recruitment to pancreatic tumours
Freeman, Patrick, Bellomo, Gaia, Ireland, Lucy, Abudula, Maidinaimu, Luckett, Teifion, Oberst, Michael, Stafferton, Ruth, Ghaneh, Paula, Halloran, Chris, Schmid, Michael C, Mielgo, Ainhoa
Published in Frontiers in immunology (05.08.2024)
Published in Frontiers in immunology (05.08.2024)
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A Novel Murine GITR Ligand Fusion Protein Induces Antitumor Activity as a Monotherapy That Is Further Enhanced in Combination with an OX40 Agonist
Leyland, Rebecca, Watkins, Amanda, Mulgrew, Kathy A, Holoweckyj, Nicholas, Bamber, Lisa, Tigue, Natalie J, Offer, Emily, Andrews, John, Yan, Li, Mullins, Stefanie, Oberst, Michael D, Coates Ulrichsen, Jane, Leinster, David A, McGlinchey, Kelly, Young, Lesley, Morrow, Michelle, Hammond, Scott A, Mallinder, Philip, Herath, Athula, Leow, Ching Ching, Wilkinson, Robert W, Stewart, Ross
Published in Clinical cancer research (01.07.2017)
Published in Clinical cancer research (01.07.2017)
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Potent Immune Modulation by MEDI6383, an Engineered Human OX40 Ligand IgG4P Fc Fusion Protein
Oberst, Michael D, Augé, Catherine, Morris, Chad, Kentner, Stacy, Mulgrew, Kathy, McGlinchey, Kelly, Hair, James, Hanabuchi, Shino, Du, Qun, Damschroder, Melissa, Feng, Hui, Eck, Steven, Buss, Nicholas, de Haan, Lolke, Pierce, Andrew J, Park, Haesun, Sylwester, Andrew, Axthelm, Michael K, Picker, Louis, Morris, Nicholas P, Weinberg, Andrew, Hammond, Scott A
Published in Molecular cancer therapeutics (01.05.2018)
Published in Molecular cancer therapeutics (01.05.2018)
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CEA/CD3 bispecific antibody MEDI-565/AMG 211 activation of T cells and subsequent killing of human tumors is independent of mutations commonly found in colorectal adenocarcinomas
Oberst, Michael D, Fuhrmann, Stacy, Mulgrew, Kathy, Amann, Maria, Cheng, Lily, Lutterbuese, Petra, Richman, Laura, Coats, Steve, Baeuerle, Patrick A, Hammond, Scott A
Published in mAbs (2014)
Published in mAbs (2014)
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Journal Article
The CEA/CD3-bispecific antibody MEDI-565 (MT111) binds a nonlinear epitope in the full-length but not a short splice variant of CEA
Peng, Li, Oberst, Michael D, Huang, Jiaqi, Brohawn, Philip, Morehouse, Chris, Lekstrom, Kristen, Baeuerle, Patrick A, Wu, Herren, Yao, Yihong, Coats, Steven R, Dall'Acqua, William, Damschroder, Melissa, Hammond, Scott A
Published in PloS one (04.05.2012)
Published in PloS one (04.05.2012)
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Activity of murine surrogate antibodies for durvalumab and tremelimumab lacking effector function and the ability to deplete regulatory T cells in mouse models of cancer
Schofield, Darren J, Percival-Alwyn, Jennifer, Rytelewski, Mateusz, Hood, John, Rothstein, Raymond, Wetzel, Leslie, McGlinchey, Kelly, Adjei, Grace, Watkins, Amanda, Machiesky, LeeAnn, Chen, Weimin, Andrews, John, Groves, Maria, Morrow, Michelle, Stewart, Ross A, Leinster, Andrew, Wilkinson, Robert W, Hammond, Scott A, Luheshi, Nadia, Dobson, Claire, Oberst, Michael
Published in mAbs (01.01.2021)
Published in mAbs (01.01.2021)
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Activation of the RalGEF/Ral Pathway Promotes Prostate Cancer Metastasis to Bone
Yin, JuanJuan, Pollock, Claire, Tracy, Kirsten, Chock, Monika, Martin, Philip, Oberst, Michael, Kelly, Kathleen
Published in Molecular and Cellular Biology (01.11.2007)
Published in Molecular and Cellular Biology (01.11.2007)
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TDAG51 is an ERK signaling target that opposes ERK-mediated HME16C mammary epithelial cell transformation
Oberst, Michael D, Beberman, Stacey J, Zhao, Liu, Yin, Juan Juan, Ward, Yvona, Kelly, Kathleen
Published in BMC cancer (02.07.2008)
Published in BMC cancer (02.07.2008)
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HAI-1 regulates activation and expression of matriptase, a membrane-bound serine protease
Oberst, Michael D, Chen, Li-Yuan L, Kiyomiya, Ken-Ichi, Williams, Cicely A, Lee, Ming-Shyue, Johnson, Michael D, Dickson, Robert B, Lin, Chen-Yong
Published in American Journal of Physiology: Cell Physiology (01.08.2005)
Published in American Journal of Physiology: Cell Physiology (01.08.2005)
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The Activation of Matriptase Requires Its Noncatalytic Domains, Serine Protease Domain, and Its Cognate Inhibitor
Oberst, Michael D., Williams, Cicely A., Dickson, Robert B., Johnson, Michael D., Lin, Chen-Yong
Published in The Journal of biological chemistry (18.07.2003)
Published in The Journal of biological chemistry (18.07.2003)
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Anti-PD-1 monoclonal antibody MEDI0680 in a phase I study of patients with advanced solid malignancies
Naing, Aung, Infante, Jeffrey, Goel, Sanjay, Burris, Howard, Black, Chelsea, Marshall, Shannon, Achour, Ikbel, Barbee, Susannah, May, Rena, Morehouse, Chris, Pollizzi, Kristen, Song, Xuyang, Steele, Keith, Elgeioushi, Nairouz, Walcott, Farzana, Karakunnel, Joyson, LoRusso, Patricia, Weise, Amy, Eder, Joseph, Curti, Brendan, Oberst, Michael
Published in Journal for immunotherapy of cancer (22.08.2019)
Published in Journal for immunotherapy of cancer (22.08.2019)
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