A Survey of the Role of Noncovalent Sulfur Interactions in Drug Design
Beno, Brett R, Yeung, Kap-Sun, Bartberger, Michael D, Pennington, Lewis D, Meanwell, Nicholas A
Published in Journal of medicinal chemistry (11.06.2015)
Published in Journal of medicinal chemistry (11.06.2015)
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Journal Article
Systematic Study of the Glutathione Reactivity of N‑Phenylacrylamides: 2. Effects of Acrylamide Substitution
Birkholz, Adam, Kopecky, David J, Volak, Laurie P, Bartberger, Michael D, Chen, Yuping, Tegley, Christopher M, Arvedson, Tara, McCarter, John D, Fotsch, Christopher, Cee, Victor J
Published in Journal of medicinal chemistry (22.10.2020)
Published in Journal of medicinal chemistry (22.10.2020)
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Discovery of TRPM8 Antagonist (S)‑6-(((3-Fluoro-4-(trifluoromethoxy)phenyl)(3-fluoropyridin-2-yl)methyl)carbamoyl)nicotinic Acid (AMG 333), a Clinical Candidate for the Treatment of Migraine
Horne, Daniel B, Biswas, Kaustav, Brown, James, Bartberger, Michael D, Clarine, Jeffrey, Davis, Carl D, Gore, Vijay K, Harried, Scott, Horner, Michelle, Kaller, Matthew R, Lehto, Sonya G, Liu, Qingyian, Ma, Vu V, Monenschein, Holger, Nguyen, Thomas T, Yuan, Chester C, Youngblood, Beth D, Zhang, Maosheng, Zhong, Wenge, Allen, Jennifer R, Chen, Jian Jeffrey, Gavva, Narender R
Published in Journal of medicinal chemistry (27.09.2018)
Published in Journal of medicinal chemistry (27.09.2018)
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Journal Article
Structure-Based Design of Novel Inhibitors of the MDM2–p53 Interaction
Rew, Yosup, Sun, Daqing, Gonzalez-Lopez De Turiso, Felix, Bartberger, Michael D, Beck, Hilary P, Canon, Jude, Chen, Ada, Chow, David, Deignan, Jeffrey, Fox, Brian M, Gustin, Darin, Huang, Xin, Jiang, Min, Jiao, Xianyun, Jin, Lixia, Kayser, Frank, Kopecky, David J, Li, Yihong, Lo, Mei-Chu, Long, Alexander M, Michelsen, Klaus, Oliner, Jonathan D, Osgood, Tao, Ragains, Mark, Saiki, Anne Y, Schneider, Steve, Toteva, Maria, Yakowec, Peter, Yan, Xuelei, Ye, Qiuping, Yu, Dongyin, Zhao, Xiaoning, Zhou, Jing, Medina, Julio C, Olson, Steven H
Published in Journal of medicinal chemistry (14.06.2012)
Published in Journal of medicinal chemistry (14.06.2012)
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Journal Article
From Fragment Screening to In Vivo Efficacy: Optimization of a Series of 2-Aminoquinolines as Potent Inhibitors of Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1)
Cheng, Yuan, Judd, Ted C, Bartberger, Michael D, Brown, James, Chen, Kui, Fremeau, Robert T, Hickman, Dean, Hitchcock, Stephen A, Jordan, Brad, Li, Vivian, Lopez, Patricia, Louie, Steven W, Luo, Yi, Michelsen, Klaus, Nixey, Thomas, Powers, Timothy S, Rattan, Claire, Sickmier, E. Allen, St. Jean, David J, Wahl, Robert C, Wen, Paul H, Wood, Stephen
Published in Journal of medicinal chemistry (25.08.2011)
Published in Journal of medicinal chemistry (25.08.2011)
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Journal Article
Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors
Lloyd, David J., St Jean, David J., Kurzeja, Robert J. M., Wahl, Robert C., Michelsen, Klaus, Cupples, Rod, Chen, Michelle, Wu, John, Sivits, Glenn, Helmering, Joan, Komorowski, Renée, Ashton, Kate S., Pennington, Lewis D., Fotsch, Christopher, Vazir, Mukta, Chen, Kui, Chmait, Samer, Zhang, Jiandong, Liu, Longbin, Norman, Mark H., Andrews, Kristin L., Bartberger, Michael D., Van, Gwyneth, Galbreath, Elizabeth J., Vonderfecht, Steven L., Wang, Minghan, Jordan, Steven R., Véniant, Murielle M., Hale, Clarence
Published in Nature (London) (01.12.2013)
Published in Nature (London) (01.12.2013)
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Journal Article
Synthesis and structure–activity relationship of trisubstituted thiazoles as Cdc7 kinase inhibitors
Reichelt, Andreas, Bailis, Julie M., Bartberger, Michael D., Yao, Guomin, Shu, Hong, Kaller, Matthew R., Allen, John G., Weidner, Margaret F., Keegan, Kathleen S., Dao, Jennifer H.
Published in European journal of medicinal chemistry (10.06.2014)
Published in European journal of medicinal chemistry (10.06.2014)
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Journal Article
A Biochemical Rationale for the Discrete Behavior of Nitroxyl and Nitric Oxide in the Cardiovascular System
Miranda, Katrina M., Paolocci, Nazareno, Katori, Tatsuo, Thomas, Douglas D., Ford, Eleonora, Bartberger, Michael D., Espey, Michael G., Kass, David A., Feelisch, Martin, Fukuto, Jon M., Wink, David A.
Published in Proceedings of the National Academy of Sciences - PNAS (05.08.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (05.08.2003)
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Journal Article
The Reduction Potential of Nitric Oxide (NO) and Its Importance to NO Biochemistry
Bartberger, Michael D., Liu, Wei, Ford, Eleonora, Miranda, Katrina M., Switzer, Christopher, Fukuto, Jon M., Farmer, Patrick J., Wink, David A., Houk, Kendall N.
Published in Proceedings of the National Academy of Sciences - PNAS (20.08.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (20.08.2002)
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Journal Article
The Physiological Chemistry and Biological Activity of Nitroxyl (HNO): The Neglected, Misunderstood, and Enigmatic Nitrogen Oxide
Fukuto, Jon M, Bartberger, Michael D, Dutton, Andrew S, Paolocci, Nazareno, Wink, David A, Houk, K. N
Published in Chemical research in toxicology (01.05.2005)
Published in Chemical research in toxicology (01.05.2005)
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Discovery and Optimization of Potent GPR40 Full Agonists Containing Tricyclic Spirocycles
Wang, Yingcai, Liu, Jiwen (Jim), Dransfield, Paul J, Zhu, Liusheng, Wang, Zhongyu, Du, Xiaohui, Jiao, Xianyun, Su, Yongli, Li, An-rong, Brown, Sean P, Kasparian, Annie, Vimolratana, Marc, Yu, Ming, Pattaropong, Vatee, Houze, Jonathan B, Swaminath, Gayathri, Tran, Thanhvien, Nguyen, Khanh, Guo, Qi, Zhang, Jane, Zhuang, Run, Li, Frank, Miao, Lynn, Bartberger, Michael D, Correll, Tiffany L, Chow, David, Wong, Simon, Luo, Jian, Lin, Daniel C.-H, Medina, Julio C
Published in ACS medicinal chemistry letters (13.06.2013)
Published in ACS medicinal chemistry letters (13.06.2013)
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Journal Article
Insertion of Helium and Molecular Hydrogen Through the Orifice of an Open Fullerene
Rubin, Yves, Jarrosson, Thibaut, Wang, Guan-Wu, Bartberger, Michael D., Houk, K. N., Schick, Georg, Saunders, Martin, Cross, R. James
Published in Angewandte Chemie International Edition (17.04.2001)
Published in Angewandte Chemie International Edition (17.04.2001)
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Journal Article
Ir-Catalyzed Asymmetric Allylic Alkylation of Dialkyl Malonates Enabling the Construction of Enantioenriched All-Carbon Quaternary Centers
Moghadam, Farbod A., Hicks, Elliot F., Sercel, Zachary P., Cusumano, Alexander Q., Bartberger, Michael D., Stoltz, Brian M.
Published in Journal of the American Chemical Society (11.05.2022)
Published in Journal of the American Chemical Society (11.05.2022)
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Journal Article
Enantioselective synthesis of highly oxygenated acyclic quaternary center-containing building blocks via palladium-catalyzed decarboxylative allylic alkylation of cyclic siloxyketones
Ngamnithiporn, Aurapat, Iwayama, Toshihiko, Bartberger, Michael D, Stoltz, Brian M
Published in Chemical science (Cambridge) (15.09.2020)
Published in Chemical science (Cambridge) (15.09.2020)
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Journal Article
Systematic Study of the Glutathione (GSH) Reactivity of N‑Arylacrylamides: 1. Effects of Aryl Substitution
Cee, Victor J, Volak, Laurie P, Chen, Yuping, Bartberger, Michael D, Tegley, Chris, Arvedson, Tara, McCarter, John, Tasker, Andrew S, Fotsch, Christopher
Published in Journal of medicinal chemistry (10.12.2015)
Published in Journal of medicinal chemistry (10.12.2015)
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Journal Article
Fragment-Linking Approach Using (19)F NMR Spectroscopy To Obtain Highly Potent and Selective Inhibitors of β-Secretase
Jordan, John B, Whittington, Douglas A, Bartberger, Michael D, Sickmier, E Allen, Chen, Kui, Cheng, Yuan, Judd, Ted
Published in Journal of medicinal chemistry (28.04.2016)
Published in Journal of medicinal chemistry (28.04.2016)
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