ACE2 X-Ray Structures Reveal a Large Hinge-bending Motion Important for Inhibitor Binding and Catalysis
Towler, Paul, Staker, Bart, Prasad, Sridhar G., Menon, Saurabh, Tang, Jin, Parsons, Thomas, Ryan, Dominic, Fisher, Martin, Williams, David, Dales, Natalie A., Patane, Michael A., Pantoliano, Michael W.
Published in Journal of molecular biology (23.04.2004)
Published in Journal of molecular biology (23.04.2004)
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Journal Article
Multivalent Ligand-Receptor Binding Interactions in the Fibroblast Growth Factor System Produce a Cooperative Growth Factor and Heparin Mechanism for Receptor Dimerization
Pantoliano, Michael W, Horlick, Robert A, Springer, Barry A, Van Dyk, Drew E, Tobery, Timothy, Wetmore, Diana R, Lear, James D, Nahapetian, Ara T, Bradley, Jodi D, Sisk, William P
Published in Biochemistry (Easton) (30.08.1994)
Published in Biochemistry (Easton) (30.08.1994)
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Journal Article
Discovery and Cocrystal Structure of Benzodiazepinedione HDM2 Antagonists That Activate p53 in Cells
Grasberger, Bruce L, Lu, Tianbao, Schubert, Carsten, Parks, Daniel J, Carver, Theodore E, Koblish, Holly K, Cummings, Maxwell D, LaFrance, Louis V, Milkiewicz, Karen L, Calvo, Raul R, Maguire, Diane, Lattanze, Jennifer, Franks, Carol F, Zhao, Shuyuan, Ramachandren, Kannan, Bylebyl, Gwendolyn R, Zhang, Marie, Manthey, Carl L, Petrella, Eugene C, Pantoliano, Michael W, Deckman, Ingrid C, Spurlino, John C, Maroney, Anna C, Tomczuk, Bruce E, Molloy, Christopher J, Bone, Roger F
Published in Journal of medicinal chemistry (24.02.2005)
Published in Journal of medicinal chemistry (24.02.2005)
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Journal Article
Conformational stability, folding, and ligand-binding affinity of single-chain Fv immunoglobulin fragments expressed in Escherichia coli
Pantoliano, Michael W, Bird, Robert E, Johnson, Syd, Asel, Eric D, Dodd, Steven W, Wood, Jay F, Hardman, Karl D
Published in Biochemistry (Easton) (01.10.1991)
Published in Biochemistry (Easton) (01.10.1991)
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Journal Article
Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding
Pantoliano, Michael W, Whitlow, Marc, Wood, Jay F, Dodd, Steven W, Hardman, Karl D, Rollence, Michele L, Bryan, Philip N
Published in Biochemistry (Easton) (01.09.1989)
Published in Biochemistry (Easton) (01.09.1989)
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Enzymes in organic synthesis: use of subtilisin and a highly stable mutant derived from multiple site-specific mutations
Wong, Chi Huey, Chen, S. T, Hennen, William J, Bibbs, Jeffrey A, Wang, Y. F, Liu, Jennifer L. C, Pantoliano, Michael W, Whitlow, Marc, Bryan, Philip N
Published in Journal of the American Chemical Society (1990)
Published in Journal of the American Chemical Society (1990)
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Journal Article
The engineering of binding affinity at metal ion binding sites for the stabilization of proteins: subtilisin as a test case
Pantoliano, Michael W, Whitlow, Marc, Wood, Jay F, Rollence, Michele L, Finzel, Barry C, Gilliland, Gary L, Poulos, Thomas L, Bryan, Philip N
Published in Biochemistry (Easton) (01.11.1988)
Published in Biochemistry (Easton) (01.11.1988)
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Journal Article
Protein engineering of subtilisin BPN': enhanced stabilization through the introduction of two cysteines to form a disulfide bond
Pantoliano, Michael W, Ladner, Robert C, Bryan, Philip N, Rollence, Michele L, Wood, Jay F, Poulos, Thomas L
Published in Biochemistry (Easton) (01.04.1987)
Published in Biochemistry (Easton) (01.04.1987)
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Journal Article
High-Density Miniaturized Thermal Shift Assays as a General Strategy for Drug Discovery
Pantoliano, Michael W., Petrella, Eugene C., Kwasnoski, Joseph D., Lobanov, Victor S., Myslik, James, Graf, Edward, Carver, Ted, Asel, Eric, Springer, Barry A., Lane, Pamela, Salemme, F.R.
Published in SLAS discovery (01.12.2001)
Published in SLAS discovery (01.12.2001)
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Journal Article
High-density miniaturized thermal shift assays as a general strategy for drug discovery
Pantoliano, M W, Petrella, E C, Kwasnoski, J D, Lobanov, V S, Myslik, J, Graf, E, Carver, T, Asel, E, Springer, B A, Lane, P, Salemme, F R
Published in Journal of biomolecular screening (01.12.2001)
Published in Journal of biomolecular screening (01.12.2001)
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Journal Article
Crystal structure and ligand binding studies of a screened peptide complexed with streptavidin
Weber, Patricia C, Pantoliano, Michael W, Thompson, Leo D
Published in Biochemistry (Easton) (06.10.1992)
Published in Biochemistry (Easton) (06.10.1992)
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Journal Article
Nuclear magnetic resonance and chemical modification studies of bovine erythrocyte superoxide dismutase: evidence for zinc-promoted organization of the active site structure
Lippard, Stephen J, Burger, Allan R, Ugurbil, Kamil, Pantoliano, Michael W, Valentine, Joan S
Published in Biochemistry (Easton) (22.03.1977)
Published in Biochemistry (Easton) (22.03.1977)
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Journal Article
Affinity chromatographic purification of angiotensin converting enzyme
Pantoliano, Michael W, Holmquist, Barton, Riordan, James F
Published in Biochemistry (Easton) (28.02.1984)
Published in Biochemistry (Easton) (28.02.1984)
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Journal Article
Spectroscopic studies of copper(II) bound at the native copper site or substituted at the native zinc site of bovine erythrocuprein (superoxide dismutase)
Pantoliano, Michael W, Valentine, Joan S, Nafie, Lawrence A
Published in Journal of the American Chemical Society (01.11.1982)
Published in Journal of the American Chemical Society (01.11.1982)
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Journal Article
PH [hydrogen-ion concentration]-dependent migration of copper(II) to the vacant zinc-binding site of zinc-free bovine erythrocyte superoxide dismutase
Valentine, J.S, Pantoliano, M.W, McDonnell, P.J, Burger, A.R, Lippard, S.J
Published in Proceedings of the National Academy of Sciences - PNAS (01.09.1979)
Published in Proceedings of the National Academy of Sciences - PNAS (01.09.1979)
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Journal Article
Identification and concerted function of two receptor binding surfaces on basic fibroblast growth factor required for mitogenesis
Springer, B A, Pantoliano, M W, Barbera, F A, Gunyuzlu, P L, Thompson, L D, Herblin, W F, Rosenfeld, S A, Book, G W
Published in The Journal of biological chemistry (28.10.1994)
Published in The Journal of biological chemistry (28.10.1994)
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