Oncolytic H-1 Parvovirus Shows Safety and Signs of Immunogenic Activity in a First Phase I/IIa Glioblastoma Trial
Geletneky, Karsten, Hajda, Jacek, Angelova, Assia L., Leuchs, Barbara, Capper, David, Bartsch, Andreas J., Neumann, Jan-Oliver, Schöning, Tilman, Hüsing, Johannes, Beelte, Birgit, Kiprianova, Irina, Roscher, Mandy, Bhat, Rauf, von Deimling, Andreas, Brück, Wolfgang, Just, Alexandra, Frehtman, Veronika, Löbhard, Stephanie, Terletskaia-Ladwig, Elena, Fry, Jeremy, Jochims, Karin, Daniel, Volker, Krebs, Ottheinz, Dahm, Michael, Huber, Bernard, Unterberg, Andreas, Rommelaere, Jean
Published in Molecular therapy (06.12.2017)
Published in Molecular therapy (06.12.2017)
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Phase I/IIa study of intratumoral/intracerebral or intravenous/intracerebral administration of Parvovirus H-1 (ParvOryx) in patients with progressive primary or recurrent glioblastoma multiforme: ParvOryx01 protocol
Geletneky, Karsten, Huesing, Johannes, Rommelaere, Jean, Schlehofer, Joerg R, Leuchs, Barbara, Dahm, Michael, Krebs, Ottheinz, von Knebel Doeberitz, Magnus, Huber, Bernard, Hajda, Jacek
Published in BMC cancer (21.03.2012)
Published in BMC cancer (21.03.2012)
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A non-controlled, single arm, open label, phase II study of intravenous and intratumoral administration of ParvOryx in patients with metastatic, inoperable pancreatic cancer: ParvOryx02 protocol
Hajda, Jacek, Lehmann, Monika, Krebs, Ottheinz, Kieser, Meinhard, Geletneky, Karsten, Jäger, Dirk, Dahm, Michael, Huber, Bernard, Schöning, Tilman, Sedlaczek, Oliver, Stenzinger, Albrecht, Halama, Niels, Daniel, Volker, Leuchs, Barbara, Angelova, Assia, Rommelaere, Jean, Engeland, Christine E, Springfeld, Christoph, Ungerechts, Guy
Published in BMC cancer (29.08.2017)
Published in BMC cancer (29.08.2017)
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Performance of T-Track® SARS-CoV-2, an Innovative Dual Marker RT-qPCR-Based Whole-Blood Assay for the Detection of SARS-CoV-2-Reactive T Cells
Kanis, Franziska M, Meier, Johannes P, Guldan, Harald, Niller, Hans-Helmut, Dahm, Michael, Dansard, Alexander, Zander, Thomas, Struck, Friedhelm, Soutschek, Erwin, Deml, Ludwig, Möbus, Selina, Barabas, Sascha
Published in Diagnostics (Basel) (22.08.2023)
Published in Diagnostics (Basel) (22.08.2023)
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Phase 2 Trial of Oncolytic H-1 Parvovirus Therapy Shows Safety and Signs of Immune System Activation in Patients With Metastatic Pancreatic Ductal Adenocarcinoma
Hajda, Jacek, Leuchs, Barbara, Angelova, Assia L, Frehtman, Veronika, Rommelaere, Jean, Mertens, Mieke, Pilz, Maximilian, Kieser, Meinhard, Krebs, Ottheinz, Dahm, Michael, Huber, Bernard, Engeland, Christine E, Mavratzas, Athanasios, Hohmann, Nicolas, Schreiber, Jutta, Jäger, Dirk, Halama, Niels, Sedlaczek, Oliver, Gaida, Matthias M, Daniel, Volker, Springfeld, Christoph, Ungerechts, Guy
Published in Clinical cancer research (15.10.2021)
Published in Clinical cancer research (15.10.2021)
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CANCER THERAPY WITH PARVOVIRUS COMBINED WITH BEVACIZUMAB
WICK WOLFGANG, ANTJE WICK, KARSTEN GELETNEKY, JEAN ROMMELAERE, MICHAEL DAHM
Year of Publication 28.11.2019
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Year of Publication 28.11.2019
Patent
First combined intravenous and intracerebral application of an oncolytic virus, parvovirus h-1, in a phase I/IIa clinical trial in patients with recurrent glioblastoma multiforme (ParvOryx01)
Geletneky, Karsten, Huesing, Johannes, Dahm, Michael, Krebs, Ottheinz, Huber, Bernard, Capper, David, Rommelaere, Jean, Hajda, Jacek, Unterberg, Andreas
Published in Journal of clinical oncology (20.05.2014)
Published in Journal of clinical oncology (20.05.2014)
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Bioavailability, Biodistribution, and CNS Toxicity of Clinical-Grade Parvovirus H1 after Intravenous and Intracerebral Injection in Rats
Geletneky, Karsten, Leoni, Anne-Laure, Pohlmeyer-Esch, Gabriele, Loebhard, Stephanie, Leuchs, Barbara, Hoefer, Constance, Jochims, Karin, Dahm, Michael, Huber, Bernard, Rommelaere, Jean, Krebs, Ottheinz, Hajda, Jacek
Published in Comparative medicine (01.02.2015)
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Published in Comparative medicine (01.02.2015)
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ET-21COMBINATION OF INTRAVENOUS AND INTRACEREBRAL INJECTION OF ONCOLYTIC PARVOVIRUS H-1 IN A PHASE I/IIA CLINICAL TRIAL OF PATIENTS WITH RECURRENT GLIOBLASTOMA MULTIFORME: PENETRATION OF H-1 VIRUS ACROSS THE BLOOD-BRAIN BARRIER
Geletneky, Karsten, Angelova, Assia, Leuchs, Barbara, Bhat, Rauf, Just, Alexandra, Capper, David, Krebs, Ottheinz, Dahm, Michael, Huber, Bernard, Unterberg, Andreas, Hajda, Jacek, Rommelaere, Jean
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2014)
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2014)
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Pathology, Organ Distribution, and Immune Response after Single and Repeated Intravenous Injection of Rats with Clinical-Grade Parvovirus H1
Geletneky, Karsten, Leoni, Anne-Laure, Pohlmeyer-Esch, Gabriele, Loebhard, Stephanie, Baetz, Andrea, Leuchs, Barbara, Roscher, Mandy, Hoefer, Constance, Jochims, Karin, Dahm, Michael, Huber, Bernard, Rommelaere, Jean, Krebs, Ottheinz, Hajda, Jacek
Published in Comparative medicine (01.02.2015)
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Published in Comparative medicine (01.02.2015)
Journal Article
ET-21 COMBINATION OF INTRAVENOUS AND INTRACEREBRAL INJECTION OF ONCOLYTIC PARVOVIRUS H-1 IN A PHASE I/IIA CLINICAL TRIAL OF PATIENTS WITH RECURRENT GLIOBLASTOMA MULTIFORME: PENETRATION OF H-1 VIRUS ACROSS THE BLOOD-BRAIN BARRIER
Geletneky, K., Angelova, A., Leuchs, B., Bhat, R., Just, A., Capper, D., Krebs, O., Dahm, M., Huber, B., Unterberg, A., Hajda, J., Rommelaere, J.
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2014)
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2014)
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Correlation of CK‐20‐Positive Cells in Peripheral Venous Blood with Serum CEA Levels in Patients with Colorectal Carcinoma
Friederichs, Jan, Gertler, Ralf, Rosenberg, Robert, Dahm, Michael, Nekarda, Hjalmar, Holzmann, Bernhard, Siewert, Jörg Rüdiger
Published in World journal of surgery (01.12.2007)
Published in World journal of surgery (01.12.2007)
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KRÆFTBEHANDLING MED EN PARVOVIRUS KOMBINERET MED BEVACIZUMAB
WICK, Wolfgang, GELETNEKY, Karsten, ROMMELAERE, Jean, WICK, Antje, DAHM, Michael
Year of Publication 19.02.2024
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Year of Publication 19.02.2024
Patent
CANCER THERAPY WITH A PARVOVIRUS COMBINED WITH BEVACIZUMAB
WICK, Wolfgang, GELETNEKY, Karsten, ROMMELAERE, Jean, WICK, Antje, DAHM, Michael
Year of Publication 06.12.2023
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Year of Publication 06.12.2023
Patent
Cancer therapy with an oncolytic virus combined with a checkpoint inhibitor
Leuchs, Barbara, Angelova, Assia, Dahm, Michael, Marchini, Antonio, Jager, Dirk, Rommelaere, Jean, Wick, Wolfgang
Year of Publication 23.04.2024
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Year of Publication 23.04.2024
Patent