An integrative drug repositioning framework discovered a potential therapeutic agent targeting COVID-19
Ge, Yiyue, Tian, Tingzhong, Huang, Suling, Wan, Fangping, Li, Jingxin, Li, Shuya, Wang, Xiaoting, Yang, Hui, Hong, Lixiang, Wu, Nian, Yuan, Enming, Luo, Yunan, Cheng, Lili, Hu, Chengliang, Lei, Yipin, Shu, Hantao, Feng, Xiaolong, Jiang, Ziyuan, Wu, Yunfu, Chi, Ying, Guo, Xiling, Cui, Lunbiao, Xiao, Liang, Li, Zeng, Yang, Chunhao, Miao, Zehong, Chen, Ligong, Li, Haitao, Zeng, Hainian, Zhao, Dan, Zhu, Fengcai, Shen, Xiaokun, Zeng, Jianyang
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Published in Signal transduction and targeted therapy (24.04.2021)
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One Pot and Metal-Free Approach to 3-(2-Hydroxybenzoyl)-1-aza-anthraquinones
Yuan, Jiaqi, He, Qian, Song, Shanshan, Zhang, Xiaofei, Miao, Zehong, Yang, Chunhao
Published in Molecules (Basel, Switzerland) (20.08.2019)
Published in Molecules (Basel, Switzerland) (20.08.2019)
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Discovery of a series of 1H-pyrrolo[2,3-b]pyridine compounds as potent TNIK inhibitors
Yang, Bowen, Wu, Qian, Huan, Xiajuan, Wang, Yingqing, Sun, Yin, Yang, Yueyue, Liu, Tongchao, Wang, Xin, Chen, Lin, Xiong, Bing, Zhao, Dongmei, Miao, Zehong, Chen, Danqi
Published in Bioorganic & medicinal chemistry letters (01.02.2021)
Published in Bioorganic & medicinal chemistry letters (01.02.2021)
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Three-Component, One-Pot Sequential Synthesis of Tetracyclic Pyrido[2′,1′:2,3]imidazo[5,1-a]isoquinolinium Compounds as Potent Anticancer Agents
Zhou, Huayong, Wang, Wei, Khorev, Oleg, Zhang, Yongliang, Miao, Zehong, Meng, Tao, Shen, Jingkang
Published in European journal of organic chemistry (01.10.2012)
Published in European journal of organic chemistry (01.10.2012)
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Design, synthesis, and anticancer activities of new compounds bearing the quinone–pyran–lactone tricyclic pharmacophore
Jiang, Xue, Wang, Meining, Song, Shanshan, Xu, Youjun, Miao, Zehong, Zhang, Ao
Published in RSC advances (01.01.2015)
Published in RSC advances (01.01.2015)
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Cytotoxic Dihydroagarofuranoid Sesquiterpenes from the Seeds of Celastrus orbiculatus
Zhu, Yingdong, Miao, Zehong, Ding, Jian, Zhao, Weimin
Published in Journal of natural products (Washington, D.C.) (01.06.2008)
Published in Journal of natural products (Washington, D.C.) (01.06.2008)
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Chimmitecan, a Novel 9-Substituted Camptothecin, with Improved Anticancer Pharmacologic Profiles In vitro and In vivo
Huang, Min, Gao, Heyong, Chen, Yi, Zhu, Hong, Cai, Yujun, Zhang, Xiongwen, Miao, Zehong, Jiang, Hualiang, Zhang, Jian, Shen, Hongwu, Lin, Liping, Lu, Wei, Ding, Jian
Published in Clinical cancer research (15.02.2007)
Published in Clinical cancer research (15.02.2007)
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Synthesis and biological evaluation of novel triptolide analogues for anticancer activity
Zhou, Bing, Miao, Zehong, Deng, Gang, Ding, Jian, Yang, Yaxi, Feng, Huijin, Li, Yuanchao
Published in Bioorganic & medicinal chemistry letters (01.11.2010)
Published in Bioorganic & medicinal chemistry letters (01.11.2010)
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Structural Modification of Natural Product Tanshinone I Leading to Discovery of Novel Nitrogen-Enriched Derivatives with Enhanced Anticancer Profile and Improved Drug-like Properties
Ding, Chunyong, Tian, Qianting, Li, Jie, Jiao, Mingkun, Song, Shanshan, Wang, Yingqing, Miao, Zehong, Zhang, Ao
Published in Journal of medicinal chemistry (08.02.2018)
Published in Journal of medicinal chemistry (08.02.2018)
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Synthesis of OSW-1 analogues and a dimer and their antitumor activities
Ma, Xingquan, Yu, Biao, Hui, Yongzheng, Miao, Zehong, Ding, Jian
Published in Bioorganic & medicinal chemistry letters (20.08.2001)
Published in Bioorganic & medicinal chemistry letters (20.08.2001)
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Design and development of a novel series of oral bivalent BET inhibitors with potent anticancer activities
Luo, Menglan, Wu, Qian, Yang, Yueyue, Sun, Lin, Huan, Xiajuan, Tian, Changqing, Xiong, Bing, Miao, Zehong, Wang, Yingqing, Chen, Danqi
Published in European journal of medicinal chemistry (05.09.2022)
Published in European journal of medicinal chemistry (05.09.2022)
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Multi-omics characterization of WNT pathway reactivation to ameliorate BET inhibitor resistance in liver cancer cells
Liu, Yuwei, Xue, Mengzhu, Cao, Danyan, Qin, Lihuai, Wang, Ying, Miao, Zehong, Wang, Peng, Hu, Xin, Shen, Jingkang, Xiong, Bing
Published in Genomics (San Diego, Calif.) (01.05.2021)
Published in Genomics (San Diego, Calif.) (01.05.2021)
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Discovery of novel 2-phenyl-imidazo[1,2-a]pyridine analogues targeting tubulin polymerization as antiproliferative agents
An, Weiteng, Wang, Wei, Yu, Ting, Zhang, Yongliang, Miao, Zehong, Meng, Tao, Shen, Jingkang
Published in European journal of medicinal chemistry (13.04.2016)
Published in European journal of medicinal chemistry (13.04.2016)
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YCH1899, a Highly Effective Phthalazin-1(2H)‑one Derivative That Overcomes Resistance to Prior PARP Inhibitors
Sun, Yuting, Yang, Hui, Yuan, Jiaqi, Wang, Limin, Song, Shanshan, Chen, Rongrong, Bao, Xubin, Jia, Li, Yang, Tiantian, Zhang, Xiaofei, He, Qian, Gan, Yong, Miao, Zehong, He, Jinxue, Yang, Chunhao
Published in Journal of medicinal chemistry (14.09.2023)
Published in Journal of medicinal chemistry (14.09.2023)
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Inulin based glutathione-responsive delivery system for colon cancer treatment
Wang, Dongdong, Sun, Feifei, Lu, Chunbo, Chen, Peng, Wang, Zhaojie, Qiu, Yuanhao, Mu, Haibo, Miao, Zehong, Duan, Jinyou
Published in International journal of biological macromolecules (01.05.2018)
Published in International journal of biological macromolecules (01.05.2018)
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Fragment-Based Drug Discovery of 2‑Thiazolidinones as Inhibitors of the Histone Reader BRD4 Bromodomain
Zhao, Lele, Cao, Danyan, Chen, Tiantian, Wang, Yingqing, Miao, Zehong, Xu, Yechun, Chen, Wuyan, Wang, Xin, Li, Yanlian, Du, Zhiyan, Xiong, Bing, Li, Jian, Xu, Chunyan, Zhang, Naixia, He, Jianhua, Shen, Jingkang
Published in Journal of medicinal chemistry (23.05.2013)
Published in Journal of medicinal chemistry (23.05.2013)
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