Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury
Pyzik, Michal, Rath, Timo, Kuo, Timothy T., Win, Sanda, Baker, Kristi, Hubbard, Jonathan J., Grenha, Rosa, Gandhi, Amit, Krämer, Thomas D., Mezo, Adam R., Taylor, Zachary S., McDonnell, Kevin, Nienaber, Vicki, Andersen, Jan Terje, Mizoguchi, Atsushi, Blumberg, Laurence, Purohit, Shalaka, Jones, Susan D., Christianson, Greg, Lencer, Wayne I., Sandlie, Inger, Kaplowitz, Neil, Roopenian, Derry C., Blumberg, Richard S.
Published in Proceedings of the National Academy of Sciences - PNAS (04.04.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (04.04.2017)
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A Synthetic Route to Human Insulin Using Isoacyl Peptides
Liu, Fa, Luo, Ethan Y., Flora, David B., Mezo, Adam R.
Published in Angewandte Chemie International Edition (07.04.2014)
Published in Angewandte Chemie International Edition (07.04.2014)
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Journal Article
Irreversible Sortase A‑Mediated Ligation Driven by Diketopiperazine Formation
Liu, Fa, Luo, Ethan Y, Flora, David B, Mezo, Adam R
Published in Journal of organic chemistry (17.01.2014)
Published in Journal of organic chemistry (17.01.2014)
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Journal Article
Insulin exits skeletal muscle capillaries by fluid-phase transport
Williams, Ian M, Valenzuela, Francisco A, Kahl, Steven D, Ramkrishna, Doraiswami, Mezo, Adam R, Young, Jamey D, Wells, K Sam, Wasserman, David H
Published in The Journal of clinical investigation (01.02.2018)
Published in The Journal of clinical investigation (01.02.2018)
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Discovery and structure–activity relationships of small molecules that block the human immunoglobulin G–human neonatal Fc receptor (hIgG–hFcRn) protein–protein interaction
Wang, Zhaolin, Fraley, Cara, Mezo, Adam R.
Published in Bioorganic & medicinal chemistry letters (01.03.2013)
Published in Bioorganic & medicinal chemistry letters (01.03.2013)
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Journal Article
Neonatal Fc Receptor Promotes Immune Complex-Mediated Glomerular Disease
OLARU, Florina, WENTIAN LUO, HANI SULEIMAN, ST. JOHN, Patricia L, GE, Linna, MEZO, Adam R, SHAW, Andrey S, ABRAHAMSON, Dale R, MINER, Jeffrey H, BORZA, Dorin-Bogdan
Published in Journal of the American Society of Nephrology (01.05.2014)
Published in Journal of the American Society of Nephrology (01.05.2014)
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Journal Article
Reduction of IgG in Nonhuman Primates by a Peptide Antagonist of the Neonatal Fc Receptor FcRn
Mezo, Adam R., McDonnell, Kevin A., Hehir, Cristina A. Tan, Low, Susan C., Palombella, Vito J., Stattel, James M., Kamphaus, George D., Fraley, Cara, Zhang, Yixia, Dumont, Jennifer A., Bitonti, Alan J.
Published in Proceedings of the National Academy of Sciences - PNAS (19.02.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (19.02.2008)
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Journal Article
Structure–activity relationships of a peptide inhibitor of the human FcRn:human IgG interaction
Mezo, Adam R., McDonnell, Kevin A., Castro, Alfredo, Fraley, Cara
Published in Bioorganic & medicinal chemistry (15.06.2008)
Published in Bioorganic & medicinal chemistry (15.06.2008)
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Journal Article
Atrial Natriuretic Peptide-Fc, ANP-Fc, Fusion Proteins: Semisynthesis, In Vitro Activity and Pharmacokinetics in Rats
Mezo, Adam R, McDonnell, Kevin A, Low, Susan C, Song, Jeff, Reidy, Tom J, Lu, Qi, Amari, John V, Hoehn, Todd, Peters, Robert T, Dumont, Jennifer, Bitonti, Alan J
Published in Bioconjugate chemistry (21.03.2012)
Published in Bioconjugate chemistry (21.03.2012)
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Journal Article
Synthesis and Structure−Activity Relationships of Dimeric Peptide Antagonists of the Human Immunoglobulin G−Human Neonatal Fc Receptor (IgG−FcRn) Interaction
McDonnell, Kevin A, Low, Susan C, Hoehn, Todd, Donnelly, Ryan, Palmieri, Holly, Fraley, Cara, Sakorafas, Paul, Mezo, Adam R
Published in Journal of medicinal chemistry (25.02.2010)
Published in Journal of medicinal chemistry (25.02.2010)
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Journal Article
Fully human monoclonal antibody inhibitors of the neonatal fc receptor reduce circulating IgG in non-human primates
Nixon, Andrew E, Chen, Jie, Sexton, Daniel J, Muruganandam, Arumugam, Bitonti, Alan J, Dumont, Jennifer, Viswanathan, Malini, Martik, Diana, Wassaf, Dina, Mezo, Adam, Wood, Clive R, Biedenkapp, Joseph C, TenHoor, Chris
Published in Frontiers in immunology (23.04.2015)
Published in Frontiers in immunology (23.04.2015)
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Enantioselective synthesis and application of the highly fluorescent and environment-sensitive amino acid 6-(2-dimethylaminonaphthoyl) alanine (DANA)Electronic supplementary information (ESI) available: experimental details. See http://www.rsc.org/suppdata/cc/b2/b205224e
Nitz, Mark, Mezo, Adam R., Ali, Mayssam H., Imperiali, Barbara
Published in Chemical communications (Cambridge, England) (21.08.2002)
Published in Chemical communications (Cambridge, England) (21.08.2002)
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