Search Results - "MEWSHAW, Richard E" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Estrogen Receptor β Agonism Increases Survival in Experimentally Induced Sepsis and Ameliorates the Genomic Sepsis Signature: A Pharmacogenomic Study

Estrogen Receptor β Agonism Increases Survival in Experimentally Induced Sepsis and Ameliorates the Genomic Sepsis Signature: A Pharmacogenomic Study

by Christaki, Eirini, Opal, Steven M., Keith, James C., Kessinian, Nubar, Palardy, John E., Parejo, Nicolas A., Lavallie, Edward, Racie, Lisa, Mounts, William, Malamas, Michael S., Mewshaw, Richard E., Harris, Heather A., Vlasuk, George P.
Published in The Journal of infectious diseases (15.04.2010)

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Studies toward the discovery of the next generation of antidepressants. Part 6: Dual 5-HT1A receptor and serotonin transporter affinity within a class of arylpiperazinyl-cyclohexyl indole derivatives

Studies toward the discovery of the next generation of antidepressants. Part 6: Dual 5-HT1A receptor and serotonin transporter affinity within a class of arylpiperazinyl-cyclohexyl indole derivatives

by DAHUI ZHOU, PING ZHOU, SMITH, Deborah L, ANDREE, Terrance H, MEWSHAW, Richard E, EVRARD, Deborah A, MEAGHER, Kristin, WEBB, Michael, HARRISON, Boyd L, HURYN, Donna M, GOLEMBIESKI, Jeannette, HOMBY, Geoffrey A, SCHECHTER, Lee E
Published in Bioorganic & medicinal chemistry (15.07.2008)

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Evaluation of an Estrogen Receptor-β Agonist in Animal Models of Human Disease

Evaluation of an Estrogen Receptor-β Agonist in Animal Models of Human Disease

by Harris, Heather A, Albert, Leo M, Leathurby, Yelena, Malamas, Michael S, Mewshaw, Richard E, Miller, Chris P, Kharode, Yogendra P, Marzolf, James, Komm, Barry S, Winneker, Richard C, Frail, Donald E, Henderson, Ruth A, Zhu, Yuan, Keith, James C
Published in Endocrinology (Philadelphia) (01.10.2003)

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ERβ ligands. Part 6 6H -Chromeno [4,3 -b]quinolines as a new series of estrogen receptor β-selective ligands

ERβ ligands. Part 6 6H -Chromeno [4,3 -b]quinolines as a new series of estrogen receptor β-selective ligands

by VU, An T, CAMPBELL, Alison N, HARRIS, Heather A, UNWALLA, Rayomand J, MANAS, Eric S, MEWSHAW, Richard E
Published in Bioorganic & medicinal chemistry letters (15.07.2007)

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ERβ Ligands. 3. Exploiting Two Binding Orientations of the 2-Phenylnaphthalene Scaffold To Achieve ERβ Selectivity

ERβ Ligands. 3. Exploiting Two Binding Orientations of the 2-Phenylnaphthalene Scaffold To Achieve ERβ Selectivity

by Mewshaw, Richard E, Edsall, Richard J, Yang, Cuijian, Manas, Eric S, Xu, Zhang B, Henderson, Ruth A, Keith, James C, Harris, Heather A
Published in Journal of medicinal chemistry (16.06.2005)

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ERβ ligands. Part 4: Synthesis and structure–activity relationships of a series of 2-phenylquinoline derivatives

ERβ ligands. Part 4: Synthesis and structure–activity relationships of a series of 2-phenylquinoline derivatives

by Vu, An T., Cohn, Stephen T., Manas, Eric S., Harris, Heather A., Mewshaw, Richard E.
Published in Bioorganic & medicinal chemistry letters (15.10.2005)

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Advances toward New Antidepressants with Dual Serotonin Transporter and 5-HT1A Receptor Affinity within a Class of 3-Aminochroman Derivatives. Part 2

Advances toward New Antidepressants with Dual Serotonin Transporter and 5-HT1A Receptor Affinity within a Class of 3-Aminochroman Derivatives. Part 2

by Hatzenbuhler, Nicole T, Baudy, Reinhardt, Evrard, Deborah A, Failli, Amedeo, Harrison, Boyd L, Lenicek, Steven, Mewshaw, Richard E, Saab, Annmarie, Shah, Uresh, Sze, Jean, Zhang, Minsheng, Zhou, Dahui, Chlenov, Michael, Kagan, Michael, Golembieski, Jeannette, Hornby, Geoffrey, Lai, Margaret, Smith, Deborah L, Sullivan, Kelly M, Schechter, Lee E, Andree, Terrance H
Published in Journal of medicinal chemistry (13.11.2008)

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ERβ ligands. Part 5: Synthesis and structure–activity relationships of a series of 4′-hydroxyphenyl-aryl-carbaldehyde oxime derivatives

ERβ ligands. Part 5: Synthesis and structure–activity relationships of a series of 4′-hydroxyphenyl-aryl-carbaldehyde oxime derivatives

by Mewshaw, Richard E., Bowen, S. Marc, Harris, Heather A., Xu, Zhang B., Manas, Eric S., Cohn, Stephen T.
Published in Bioorganic & medicinal chemistry letters (15.02.2007)

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Studies toward the Discovery of the Next Generation of Antidepressants. 3. Dual 5-HT1A and Serotonin Transporter Affinity within a Class of N-Aryloxyethylindolylalkylamines

Studies toward the Discovery of the Next Generation of Antidepressants. 3. Dual 5-HT1A and Serotonin Transporter Affinity within a Class of N-Aryloxyethylindolylalkylamines

by Mewshaw, Richard E, Zhou, Dahui, Zhou, Ping, Shi, Xiaojie, Hornby, Geoffrey, Spangler, Taylor, Scerni, Rosemary, Smith, Deborah, Schechter, Lee E, Andree, Terrance H
Published in Journal of medicinal chemistry (15.07.2004)

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Studies toward the discovery of the next generation of antidepressants. Part 5 : 3,4-Dihydro-2H-benzo[1,4]oxazine derivatives with dual 5-HT1A receptor and serotonin transporter affinity

Studies toward the discovery of the next generation of antidepressants. Part 5 : 3,4-Dihydro-2H-benzo[1,4]oxazine derivatives with dual 5-HT1A receptor and serotonin transporter affinity

by DAHUI ZHOU, HARRISON, Boyd L, SHAH, Uresh, ANDREE, Terrance H, HOMBY, Geoffrey A, SCERNI, Rosemary, SCHECHTER, Lee E, SMITH, Deborah L, SULLIVAN, Kelly M, MEWSHAW, Richard E
Published in Bioorganic & medicinal chemistry letters (01.03.2006)

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ER β Ligands. Part 1: The discovery of ER β selective ligands which embrace the 4-hydroxy-biphenyl template

ER β Ligands. Part 1: The discovery of ER β selective ligands which embrace the 4-hydroxy-biphenyl template

by Edsall, Richard J, Harris, Heather A, Manas, Eric S, Mewshaw, Richard E
Published in Bioorganic & medicinal chemistry (05.08.2003)

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Synthesis and Biological Evaluation of Novel Compounds within a Class of 3-Aminochroman Derivatives with Dual 5-HT1A Receptor and Serotonin Transporter Affinity

Synthesis and Biological Evaluation of Novel Compounds within a Class of 3-Aminochroman Derivatives with Dual 5-HT1A Receptor and Serotonin Transporter Affinity

by Hatzenbuhler, Nicole T, Evrard, Deborah A, Harrison, Boyd L, Huryn, Donna, Inghrim, Jennifer, Kraml, Christina, Mattes, James F, Mewshaw, Richard E, Zhou, Dahui, Hornby, Geoffrey, Lin, Qian, Smith, Deborah L, Sullivan, Kelly M, Schechter, Lee E, Beyer, Chad E, Andree, Terrance H
Published in Journal of medicinal chemistry (27.07.2006)

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ERβ Ligands. Part 2: Synthesis and structure–activity relationships of a series of 4-hydroxy-biphenyl-carbaldehyde oxime derivatives

ERβ Ligands. Part 2: Synthesis and structure–activity relationships of a series of 4-hydroxy-biphenyl-carbaldehyde oxime derivatives

by Yang, Cuijian, Edsall, Richard, Harris, Heather A, Zhang, Xiaochun, Manas, Eric S, Mewshaw, Richard E
Published in Bioorganic & medicinal chemistry (15.05.2004)

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Estrogen receptor β ligands: Design and synthesis of new 2-phenyl-isoindole-1,3-diones

Estrogen receptor β ligands: Design and synthesis of new 2-phenyl-isoindole-1,3-diones

by Ullrich, John W., Unwalla, Rayomand J., Singhaus, Robert R., Harris, Heather A., Mewshaw, Richard E.
Published in Bioorganic & medicinal chemistry letters (2007)

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Studies towards the next generation of antidepressants. Part 4: Derivatives of 4-(5-fluoro-1H-indol-3-yl)cyclohexylamine with affinity for the serotonin transporter and the 5-HT1A receptor

Studies towards the next generation of antidepressants. Part 4: Derivatives of 4-(5-fluoro-1H-indol-3-yl)cyclohexylamine with affinity for the serotonin transporter and the 5-HT1A receptor

by EVRARD, Deborah A, PING ZHOU, YI, Soo Y, DAHUI ZHOU, SMITH, Deborah L, SULLIVAN, Kelly M, HORNBY, Geoffrey A, SCHECHTER, Lee E, ANDREE, Terrance H, MEWSHAW, Richard E
Published in Bioorganic & medicinal chemistry letters (15.02.2005)

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Fluorenylalkanoic and Benzoic Acids as Novel Inhibitors of Cell Adhesion Processes in Leukocytes

Fluorenylalkanoic and Benzoic Acids as Novel Inhibitors of Cell Adhesion Processes in Leukocytes

by Hamilton, Gregory S, Mewshaw, Richard E, Bryant, Carmen M, Feng, Ying, Endemann, Gerda, Madden, Kip S, Danczak, Jennifer E, Perumattam, John, Stanton, Lawrence W
Published in Journal of medicinal chemistry (01.05.1995)

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Studies toward the discovery of the next generation of antidepressants. Part 2: Incorporating a 5-HT1A antagonist component into a class of serotonin reuptake inhibitors

Studies toward the discovery of the next generation of antidepressants. Part 2: Incorporating a 5-HT1A antagonist component into a class of serotonin reuptake inhibitors

by MEWSHAW, Richard E, MEAGHER, Kristin L, PING ZHOU, DAHUI ZHOU, XIAOJIE SHI, SCERNI, Rosemary, SMITH, Deborah, SCHECHTER, Lee E, ANDREE, Terrance H
Published in Bioorganic & medicinal chemistry letters (11.02.2002)

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Novel aryloxy-8-azabicyclo[3.2.1]oct-3-enes with 5-ht transporter and 5-HT1A affinity

Novel aryloxy-8-azabicyclo[3.2.1]oct-3-enes with 5-ht transporter and 5-HT1A affinity

by GILBERT, Adam M, COLEMAN, Thomas, KODAH, Jason, MEWSHAW, Richard E, SCERNI, Rosemary, SCHECHTER, Lee E, SMITH, Deborah L, ANDREE, Terrance H
Published in Bioorganic & medicinal chemistry letters (01.11.2004)

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Studies towards the next generation of antidepressants. Part 1 : Indolylcyclohexylamines as potent serotonin reuptake inhibitors

Studies towards the next generation of antidepressants. Part 1 : Indolylcyclohexylamines as potent serotonin reuptake inhibitors

by MEAGHER, Kristin L, MEWSHAW, Richard E, ANDREE, Terrance H, EVRARD, Deborah A, PING ZHOU, SMITH, Deborah L, SCERNI, Rosemary, SPANGLER, Taylor, ABULHAWA, Susan, XIAOJIE SHI, SCHECHTER, Lee E
Published in Bioorganic & medicinal chemistry letters (23.07.2001)

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Indole diterpene synthetic studies. 2. First-generation total synthesis of (-)-paspaline

Indole diterpene synthetic studies. 2. First-generation total synthesis of (-)-paspaline

by Mewshaw, Richard E, Taylor, Michael D, Smith, Amos B
Published in Journal of organic chemistry (01.07.1989)

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