Loading…
Genetic variation in catechol‐O‐methyltransferase is associated with individual differences in conditioned pain modulation in healthy subjects
Korczeniewska, Olga A., Kuo, Fengshen, Huang, Ching‐Yu, Nasri‐Heir, Cibele, Khan, Junad, Benoliel, Rafael, Hirschberg, Craig, Eliav, Eli, Diehl, Scott R.
Published in The journal of gene medicine (01.11.2021)
Published in The journal of gene medicine (01.11.2021)
Get full text
Journal Article
Loading…
Opicapone: a short lived and very long acting novel catechol‐O‐methyltransferase inhibitor following multiple dose administration in healthy subjects
Rocha, José Francisco, Almeida, Luis, Falcão, Amílcar, Palma, P. Nuno, Loureiro, Ana I., Pinto, Roberto, Bonifácio, Maria João, Wright, Lyndon C., Nunes, Teresa, Soares‐da‐Silva, Patrício
Published in British journal of clinical pharmacology (01.11.2013)
Published in British journal of clinical pharmacology (01.11.2013)
Get full text
Journal Article
Loading…
Pharmacokinetics, Pharmacodynamics and Tolerability of Opicapone, a Novel Catechol-O-Methyltransferase Inhibitor, in Healthy Subjects: Prediction of Slow Enzyme–Inhibitor Complex Dissociation of a Short-Living and Very Long-Acting Inhibitor
Almeida, Luis, Rocha, José Francisco, Falcão, Amílcar, Nuno Palma, P., Loureiro, Ana I., Pinto, Roberto, Bonifácio, Maria João, Wright, Lyndon C., Nunes, Teresa, Soares-da-Silva, Patrício
Published in Clinical pharmacokinetics (01.02.2013)
Published in Clinical pharmacokinetics (01.02.2013)
Get full text
Journal Article
Loading…
Associations between arsenic (+3 oxidation state) methyltransferase (AS3MT) and N‐6 adenine‐specific DNA methyltransferase 1 (N6AMT1) polymorphisms, arsenic metabolism, and cancer risk in a chilean population
de la Rosa, Rosemarie, Steinmaus, Craig, Akers, Nicholas K., Conde, Lucia, Ferreccio, Catterina, Kalman, David, Zhang, Kevin R., Skibola, Christine F., Smith, Allan H., Zhang, Luoping, Smith, Martyn T.
Published in Environmental and molecular mutagenesis (01.07.2017)
Published in Environmental and molecular mutagenesis (01.07.2017)
Get full text
Journal Article
Loading…
Opposite Effects of Catechol- O-Methyltransferase Val158Met on Cortical Function in Healthy Subjects and Patients with Schizophrenia
Prata, Diana P., Mechelli, Andrea, Fu, Cynthia H.Y., Picchioni, Marco, Kane, Fergus, Kalidindi, Sridevi, McDonald, Colm, Howes, Oliver, Kravariti, Eugenia, Demjaha, Arsime, Toulopoulou, Timothea, Diforti, Marta, Murray, Robin M., Collier, David A., McGuire, Philip K.
Published in Biological psychiatry (1969) (15.03.2009)
Published in Biological psychiatry (1969) (15.03.2009)
Get full text
Journal Article
Loading…
Association of Catechol-O-Methyltransferase Gene Polymorphisms and Haplotypes in the Levodopa-Induced Adverse Events in Subjects with Parkinson’s Disease
Fatima, Tasneem SD, Fathima, Syed Tazeem, Kandadai, Rukmini Mridula, Borgohain, Rupam, Sreenu, Boddupally, Kutala, Vijay Kumar
Published in Indian journal of clinical biochemistry (01.04.2023)
Published in Indian journal of clinical biochemistry (01.04.2023)
Get full text
Journal Article
Loading…
MicroRNA‐126 regulates DNA methylation in CD4+ T cells and contributes to systemic lupus erythematosus by targeting DNA methyltransferase 1
Zhao, Sha, Wang, Yu, Liang, Yunsheng, Zhao, Ming, Long, Hai, Ding, Shu, Yin, Heng, Lu, Qianjin
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2011)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2011)
Get full text
Journal Article
Loading…
Polymorphisms in Arsenic(+III Oxidation State) Methyltransferase (AS3MT) Predict Gene Expression of AS3MT as Well as Arsenic Metabolism
Engström, Karin, Vahter, Marie, Mlakar, Simona Jurkovic, Concha, Gabriela, Nermell, Barbro, Raqib, Rubhana, Cardozo, Alejandro, Broberg, Karin
Published in Environmental health perspectives (01.02.2011)
Published in Environmental health perspectives (01.02.2011)
Get full text
Journal Article
Loading…
Loading…
Associations of nicotidamide-N-methyltransferase, FTO, and IRX3 genetic variants with body mass index and resting energy expenditure in Mexican subjects
Bañales-Luna, Maciel, Figueroa-Vega, Nicté, Marín-Aragón, Carolina Ivet, Perez-Luque, Elva, Ibarra-Reynoso, Lorena, Gallardo-Blanco, Hugo L., López-Aguilar, Itzel, Malacara, Juan Manuel
Published in Scientific reports (10.07.2020)
Published in Scientific reports (10.07.2020)
Get full text
Journal Article
Loading…
Loading…
The Role of a Catechol-O-Methyltransferase (COMT) Val158Met Genetic Polymorphism in Schizophrenia: A Systematic Review and Updated Meta-analysis on 32,816 Subjects
González-Castro, Thelma Beatriz, Hernández-Díaz, Yazmin, Juárez-Rojop, Isela Esther, López-Narváez, María Lilia, Tovilla-Zárate, Carlos Alfonso, Fresan, Ana
Published in Neuromolecular medicine (01.06.2016)
Published in Neuromolecular medicine (01.06.2016)
Get full text
Journal Article
Loading…
The human methyltransferase ZCCHC4 catalyses N6-methyladenosine modification of 28S ribosomal RNA
Pinto, Rita, Vågbø, Cathrine B, Jakobsson, Magnus E, Kim, Yeji, Baltissen, Marijke P, O’Donohue, Marie-Françoise, Guzmán, Ulises H, Małecki, Jędrzej M, Wu, Jie, Kirpekar, Finn, Olsen, Jesper V, Gleizes, Pierre-Emmanuel, Vermeulen, Michiel, Leidel, Sebastian A, Slupphaug, Geir, Falnes, Pål Ø
Published in Nucleic acids research (24.01.2020)
Published in Nucleic acids research (24.01.2020)
Get full text
Journal Article
Loading…
Development of Blood–Brain Barrier Permeable Nitrocatechol-Based Catechol O‑Methyltransferase Inhibitors with Reduced Potential for Hepatotoxicity
Silva, Tiago, Mohamed, Tarek, Shakeri, Arash, Rao, Praveen P. N, Martínez-González, Loreto, Pérez, Daniel I, Martínez, Ana, Valente, Maria João, Garrido, Jorge, Uriarte, Eugenio, Serrão, Paula, Soares-da-Silva, Patrício, Remião, Fernando, Borges, Fernanda
Published in Journal of medicinal chemistry (25.08.2016)
Published in Journal of medicinal chemistry (25.08.2016)
Get full text
Journal Article
Loading…
Temozolomide Followed by Combination With Low-Dose Ipilimumab and Nivolumab in Patients With Microsatellite-Stable, O6-Methylguanine-DNA Methyltransferase-Silenced Metastatic Colorectal Cancer: The MAYA Trial
Morano, Federica, Raimondi, Alessandra, Pagani, Filippo, Lonardi, Sara, Salvatore, Lisa, Cremolini, Chiara, Murgioni, Sabina, Randon, Giovanni, Palermo, Federica, Antonuzzo, Lorenzo, Pella, Nicoletta, Racca, Patrizia, Prisciandaro, Michele, Niger, Monica, Corti, Francesca, Bergamo, Francesca, Zaniboni, Alberto, Ratti, Margherita, Palazzo, Michele, Cagnazzo, Celeste, Calegari, Maria Alessandra, Marmorino, Federica, Capone, Iolanda, Conca, Elena, Busico, Adele, Brich, Silvia, Tamborini, Elena, Perrone, Federica, Di Maio, Massimo, Milione, Massimo, Di Bartolomeo, Maria, de Braud, Filippo, Pietrantonio, Filippo
Published in Journal of clinical oncology (10.05.2022)
Published in Journal of clinical oncology (10.05.2022)
Get full text
Journal Article
Loading…
Epigenetic Regulation of Macrophage Polarization by DNA Methyltransferase 3b
Yang, Xiaosong, Wang, Xianfeng, Liu, Dongxu, Yu, Liqing, Xue, Bingzhong, Shi, Hang
Published in Molecular endocrinology (Baltimore, Md.) (01.04.2014)
Published in Molecular endocrinology (Baltimore, Md.) (01.04.2014)
Get full text
Journal Article
Loading…
Effect of Carbidopa Dose on Levodopa Pharmacokinetics With and Without Catechol-O-Methyltransferase Inhibition in Healthy Subjects
Tuunainen, Johanna, Sjöstedt, Noora, Vahteristo, Mikko, Ellmén, Juha, Kuoppamäki, Mikko, Rouru, Juha, Yliperttula, Marjo
Published in European journal of drug metabolism and pharmacokinetics (01.01.2023)
Published in European journal of drug metabolism and pharmacokinetics (01.01.2023)
Get full text
Journal Article
Loading…
Loading…
Repair gene O 6 ‐methylguanine‐DNA methyltransferase is controlled by SP1 and up‐regulated by glucocorticoids, but not by temozolomide and radiation
Aasland, Dorthe, Reich, Thomas R., Tomicic, Maja T., Switzeny, Olivier J., Kaina, Bernd, Christmann, Markus
Published in Journal of neurochemistry (01.01.2018)
Published in Journal of neurochemistry (01.01.2018)
Get full text
Journal Article
Loading…
Methylation of selenocysteine catalysed by thiopurine S-methyltransferase
Urbančič, Dunja, Kotar, Anita, Šmid, Alenka, Jukič, Marko, Gobec, Stanislav, Mårtensson, Lars-Göran, Plavec, Janez, Mlinarič-Raščan, Irena
Published in Biochimica et biophysica acta. General subjects (01.01.2019)
Published in Biochimica et biophysica acta. General subjects (01.01.2019)
Get full text
Journal Article