Fluorescent blood-brain barrier tracing shows intact leptin transport in obese mice
Harrison, Luke, Schriever, Sonja C, Feuchtinger, Annette, Kyriakou, Eleni, Baumann, Peter, Pfuhlmann, Katrin, Messias, Ana C, Walch, Axel, Tschöp, Matthias H, Pfluger, Paul T
Published in International Journal of Obesity (01.06.2019)
Published in International Journal of Obesity (01.06.2019)
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Mutations in PPCS, Encoding Phosphopantothenoylcysteine Synthetase, Cause Autosomal-Recessive Dilated Cardiomyopathy
Iuso, Arcangela, Wiersma, Marit, Schüller, Hans-Joachim, Pode-Shakked, Ben, Marek-Yagel, Dina, Grigat, Mathias, Schwarzmayr, Thomas, Berutti, Riccardo, Alhaddad, Bader, Kanon, Bart, Grzeschik, Nicola A., Okun, Jürgen G., Perles, Zeev, Salem, Yishay, Barel, Ortal, Vardi, Amir, Rubinshtein, Marina, Tirosh, Tal, Dubnov-Raz, Gal, Messias, Ana C., Terrile, Caterina, Barshack, Iris, Volkov, Alex, Avivi, Camilla, Eyal, Eran, Mastantuono, Elisa, Kumbar, Muhamad, Abudi, Shachar, Braunisch, Matthias, Strom, Tim M., Meitinger, Thomas, Hoffmann, Georg F., Prokisch, Holger, Haack, Tobias B., Brundel, Bianca J.J.M., Haas, Dorothea, Sibon, Ody C.M., Anikster, Yair
Published in American journal of human genetics (07.06.2018)
Published in American journal of human genetics (07.06.2018)
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DNA damage independent inhibition of NF-κB transcription by anthracyclines
Chora, Angelo Ferreira, Pedroso, Dora, Kyriakou, Eleni, Pejanovic, Nadja, Colaço, Henrique, Gozzelino, Raffaella, Barros, André, Willmann, Katharina, Velho, Tiago, Moita, Catarina F, Santos, Isa, Pereira, Pedro, Carvalho, Silvia, Martins, Filipa Batalha, Ferreira, João A, de Almeida, Sérgio Fernandes, Benes, Vladimir, Anrather, Josef, Weis, Sebastian, Soares, Miguel P, Geerlof, Arie, Neefjes, Jacques, Sattler, Michael, Messias, Ana C, Neves-Costa, Ana, Moita, Luis Ferreira
Published in eLife (07.12.2022)
Published in eLife (07.12.2022)
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Pitchfork and Gprasp2 Target Smoothened to the Primary Cilium for Hedgehog Pathway Activation
Jung, Bomi, Padula, Daniela, Burtscher, Ingo, Landerer, Cedric, Lutter, Dominik, Theis, Fabian, Messias, Ana C, Geerlof, Arie, Sattler, Michael, Kremmer, Elisabeth, Boldt, Karsten, Ueffing, Marius, Lickert, Heiko
Published in PloS one (22.02.2016)
Published in PloS one (22.02.2016)
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The dynamics of linear polyubiquitin
Jussupow, Alexander, Messias, Ana C, Stehle, Ralf, Geerlof, Arie, Solbak, Sara M Ø, Paissoni, Cristina, Bach, Anders, Sattler, Michael, Camilloni, Carlo
Published in Science advances (01.10.2020)
Published in Science advances (01.10.2020)
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Identification of Autophagy as a Functional Target Suitable for the Pharmacological Treatment of Mitochondrial Membrane Protein-Associated Neurodegeneration (MPAN) In Vitro
Zanuttigh, Enrica, Derderian, Kevork, Güra, Miriam A, Geerlof, Arie, Di Meo, Ivano, Cavestro, Chiara, Hempfling, Stefan, Ortiz-Collazos, Stephanie, Mauthe, Mario, Kmieć, Tomasz, Cammarota, Eugenia, Panzeri, Maria Carla, Klopstock, Thomas, Sattler, Michael, Winkelmann, Juliane, Messias, Ana C, Iuso, Arcangela
Published in Pharmaceutics (12.01.2023)
Published in Pharmaceutics (12.01.2023)
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Novel biomarkers for pre‐diabetes identified by metabolomics
Wang‐Sattler, Rui, Yu, Zhonghao, Herder, Christian, Messias, Ana C, Floegel, Anna, He, Ying, Heim, Katharina, Campillos, Monica, Holzapfel, Christina, Thorand, Barbara, Grallert, Harald, Xu, Tao, Bader, Erik, Huth, Cornelia, Mittelstrass, Kirstin, Döring, Angela, Meisinger, Christa, Gieger, Christian, Prehn, Cornelia, Roemisch‐Margl, Werner, Carstensen, Maren, Xie, Lu, Yamanaka‐Okumura, Hisami, Xing, Guihong, Ceglarek, Uta, Thiery, Joachim, Giani, Guido, Lickert, Heiko, Lin, Xu, Li, Yixue, Boeing, Heiner, Joost, Hans‐Georg, de Angelis, Martin Hrabé, Rathmann, Wolfgang, Suhre, Karsten, Prokisch, Holger, Peters, Annette, Meitinger, Thomas, Roden, Michael, Wichmann, H‐Erich, Pischon, Tobias, Adamski, Jerzy, Illig, Thomas
Published in Molecular systems biology (2012)
Published in Molecular systems biology (2012)
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Structural Basis for Recognition of the Intron Branch Site RNA by Splicing Factor 1
Liu, Zhihong, Luyten, Ingrid, Bottomley, Matthew J., Messias, Ana C., Houngninou-Molango, Sophie, Sprangers, Remco, Zanier, Katia, Krämer, Angela, Sattler, Michael
Published in Science (American Association for the Advancement of Science) (02.11.2001)
Published in Science (American Association for the Advancement of Science) (02.11.2001)
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Novel biomarkers for pre‐diabetes identified by metabolomics
Wang‐Sattler, Rui, Yu, Zhonghao, Herder, Christian, Messias, Ana C, Floegel, Anna, He, Ying, Heim, Katharina, Campillos, Monica, Holzapfel, Christina, Thorand, Barbara, Grallert, Harald, Xu, Tao, Bader, Erik, Huth, Cornelia, Mittelstrass, Kirstin, Döring, Angela, Meisinger, Christa, Gieger, Christian, Prehn, Cornelia, Roemisch‐Margl, Werner, Carstensen, Maren, Xie, Lu, Yamanaka‐Okumura, Hisami, Xing, Guihong, Ceglarek, Uta, Thiery, Joachim, Giani, Guido, Lickert, Heiko, Lin, Xu, Li, Yixue, Boeing, Heiner, Joost, Hans‐Georg, de Angelis, Martin Hrabé, Rathmann, Wolfgang, Suhre, Karsten, Prokisch, Holger, Peters, Annette, Meitinger, Thomas, Roden, Michael, Wichmann, H‐Erich, Pischon, Tobias, Adamski, Jerzy, Illig, Thomas
Published in Molecular systems biology (2012)
Published in Molecular systems biology (2012)
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Celastrol Promotes Weight Loss in Diet-Induced Obesity by Inhibiting the Protein Tyrosine Phosphatases PTP1B and TCPTP in the Hypothalamus
Kyriakou, Eleni, Schmidt, Stefanie, Dodd, Garron T, Pfuhlmann, Katrin, Simonds, Stephanie E, Lenhart, Dominik, Geerlof, Arie, Schriever, Sonja C, De Angelis, Meri, Schramm, Karl-Werner, Plettenburg, Oliver, Cowley, Michael A, Tiganis, Tony, Tschöp, Matthias H, Pfluger, Paul T, Sattler, Michael, Messias, Ana C
Published in Journal of medicinal chemistry (27.12.2018)
Published in Journal of medicinal chemistry (27.12.2018)
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Effects of metformin on metabolite profiles and LDL cholesterol in patients with type 2 diabetes
Xu, Tao, Brandmaier, Stefan, Messias, Ana C, Herder, Christian, Draisma, Harmen H M, Demirkan, Ayse, Yu, Zhonghao, Ried, Janina S, Haller, Toomas, Heier, Margit, Campillos, Monica, Fobo, Gisela, Stark, Renee, Holzapfel, Christina, Adam, Jonathan, Chi, Shen, Rotter, Markus, Panni, Tommaso, Quante, Anne S, He, Ying, Prehn, Cornelia, Roemisch-Margl, Werner, Kastenmüller, Gabi, Willemsen, Gonneke, Pool, René, Kasa, Katarina, van Dijk, Ko Willems, Hankemeier, Thomas, Meisinger, Christa, Thorand, Barbara, Ruepp, Andreas, Hrabé de Angelis, Martin, Li, Yixue, Wichmann, H-Erich, Stratmann, Bernd, Strauch, Konstantin, Metspalu, Andres, Gieger, Christian, Suhre, Karsten, Adamski, Jerzy, Illig, Thomas, Rathmann, Wolfgang, Roden, Michael, Peters, Annette, van Duijn, Cornelia M, Boomsma, Dorret I, Meitinger, Thomas, Wang-Sattler, Rui
Published in Diabetes care (01.10.2015)
Published in Diabetes care (01.10.2015)
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Structural Characterization of LRRK2 Inhibitors
Gilsbach, Bernd K, Messias, Ana C, Ito, Genta, Sattler, Michael, Alessi, Dario R, Wittinghofer, Alfred, Kortholt, Arjan
Published in Journal of medicinal chemistry (14.05.2015)
Published in Journal of medicinal chemistry (14.05.2015)
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Structural Insight into IAPP‐Derived Amyloid Inhibitors and Their Mechanism of Action
Niu, Zheng, Prade, Elke, Malideli, Eleni, Hille, Kathleen, Jussupow, Alexander, Mideksa, Yonatan G., Yan, Li‐Mei, Qian, Chen, Fleisch, Markus, Messias, Ana C., Sarkar, Riddhiman, Sattler, Michael, Lamb, Don C., Feige, Matthias J., Camilloni, Carlo, Kapurniotu, Aphrodite, Reif, Bernd
Published in Angewandte Chemie International Edition (27.03.2020)
Published in Angewandte Chemie International Edition (27.03.2020)
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Detection and quantification of the anti-obesity drug celastrol in murine liver and brain
De Angelis, Meri, Schriever, Sonja C., Kyriakou, Eleni, Sattler, Michael, Messias, Ana C., Schramm, Karl-Werner, Pfluger, Paul T.
Published in Neurochemistry international (01.06.2020)
Published in Neurochemistry international (01.06.2020)
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Celastrol-Induced Weight Loss Is Driven by Hypophagia and Independent From UCP1
Pfuhlmann, Katrin, Schriever, Sonja C, Baumann, Peter, Kabra, Dhiraj G, Harrison, Luke, Mazibuko-Mbeje, Sithandiwe E, Contreras, Raian E, Kyriakou, Eleni, Simonds, Stephanie E, Tiganis, Tony, Cowley, Michael A, Woods, Stephen C, Jastroch, Martin, Clemmensen, Christoffer, De Angelis, Meri, Schramm, Karl-Werner, Sattler, Michael, Messias, Ana C, Tschöp, Matthias H, Pfluger, Paul T
Published in Diabetes (New York, N.Y.) (01.11.2018)
Published in Diabetes (New York, N.Y.) (01.11.2018)
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Inhibition of Canonical NF-κB Signaling by a Small Molecule Targeting NEMO-Ubiquitin Interaction
Vincendeau, Michelle, Hadian, Kamyar, Messias, Ana C, Brenke, Jara K, Halander, Jenny, Griesbach, Richard, Greczmiel, Ute, Bertossi, Arianna, Stehle, Ralf, Nagel, Daniel, Demski, Katrin, Velvarska, Hana, Niessing, Dierk, Geerlof, Arie, Sattler, Michael, Krappmann, Daniel
Published in Scientific reports (07.01.2016)
Published in Scientific reports (07.01.2016)
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Novel small molecules targeting ciliary transport of Smoothened and oncogenic Hedgehog pathway activation
Jung, Bomi, Messias, Ana C, Schorpp, Kenji, Geerlof, Arie, Schneider, Günter, Saur, Dieter, Hadian, Kamyar, Sattler, Michael, Wanker, Erich E, Hasenöder, Stefan, Lickert, Heiko
Published in Scientific reports (02.03.2016)
Published in Scientific reports (02.03.2016)
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Erratum. Celastrol-Induced Weight Loss Is Driven by Hypophagia and Independent From UCP1. Diabetes 2018;67:2456-2465
Pfuhlmann, Katrin, Schriever, Sonja C, Baumann, Peter, Kabra, Dhiraj G, Harrison, Luke, Mazibuko-Mbeje, Sithandiwe E, Contreras, Raian E, Kyriakou, Eleni, Simonds, Stephanie E, Tiganis, Tony, Cowley, Michael A, Woods, Stephen C, Jastroch, Martin, Clemmensen, Christoffer, De Angelis, Meri, Schramm, Karl-Werner, Sattler, Michael, Messias, Ana C, Tschöp, Matthias H, Pfluger, Paul T
Published in Diabetes (New York, N.Y.) (01.03.2019)
Published in Diabetes (New York, N.Y.) (01.03.2019)
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