Enhanced stereoselective hydrolysis of toxic organophosphates by directly evolved variants of mammalian serum paraoxonase
Amitai, Gabriel, Gaidukov, Leonid, Adani, Rellie, Yishay, Shelly, Yacov, Guy, Kushnir, Moshe, Teitlboim, Shai, Lindenbaum, Michal, Bel, Peter, Khersonsky, Olga, Tawfik, Dan S., Meshulam, Haim
Published in The FEBS journal (01.05.2006)
Published in The FEBS journal (01.05.2006)
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Journal Article
The anti-inflammatory and cholinesterase inhibitor bifunctional compound IBU-PO protects from β-amyloid neurotoxicity by acting on Wnt signaling components
Farías, Ginny G., Godoy, Juan A., Vázquez, Mary C., Adani, Rellie, Meshulam, Haim, Avila, Jesús, Amitai, Gabi, Inestrosa, Nibaldo C.
Published in Neurobiology of disease (01.02.2005)
Published in Neurobiology of disease (01.02.2005)
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Journal Article
Novel m1 muscarinic agonists in treatment and delaying the progression of Alzheimer's disease: An unifying hypothesis
Fisher, Abraham, Brandeis, Rachel, Haring, Rachel, Eshhar, Naomi, Heldman, Eliahu, Karton, Yishai, Eisenberg, Orli, Meshulam, Haim, Marciano, Daniele, Bar-Ner, Nira, Pittel, Zipora
Published in Journal of physiology, Paris (01.10.1998)
Published in Journal of physiology, Paris (01.10.1998)
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Journal Article
Asymmetric fluorogenic organophosphates for the development of active organophosphate hydrolases with reversed stereoselectivity
Amitai, Gabi, Adani, Rellie, Yacov, Guy, Yishay, Shelly, Teitlboim, Shai, Tveria, Liat, Limanovich, Osnat, Kushnir, Moshe, Meshulam, Haim
Published in Toxicology (Amsterdam) (20.04.2007)
Published in Toxicology (Amsterdam) (20.04.2007)
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Journal Article
Conference Proceeding
IBU-Octyl-Cytisine, a novel bifunctional compound eliciting anti-inflammatory and cholinergic activity, ameliorates CNS inflammation by inhibition of T-cell activity
Nizri, Eran, Irony-Tur-Sinai, Michal, Lavon, Iris, Meshulam, Haim, Amitai, Gabi, Brenner, Talma
Published in International immunopharmacology (01.09.2007)
Published in International immunopharmacology (01.09.2007)
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Journal Article
Bifunctional compounds eliciting anti-inflammatory and anti-cholinesterase activity as potential treatment of nerve and blister chemical agents poisoning
Amitai, Gabi, Adani, Rachel, Fishbein, Eliezer, Meshulam, Haim, Laish, Ido, Dachir, Shlomit
Published in Journal of applied toxicology (01.01.2006)
Published in Journal of applied toxicology (01.01.2006)
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Journal Article
(06) Bifunctional compounds eliciting anti-inflammatory and anti-cholinesterase activity as potential treatment of nerve and blister chemical agents poisoning
Amitai, Gabi, Adani, Rachel, Fishbein, Eliezer, Meshulam, Haim, Laish, Ido, Dachir, Shlomit
Published in Chemico-biological interactions (15.12.2005)
Published in Chemico-biological interactions (15.12.2005)
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Journal Article
SPIRO BRIDGED AND UNBRIDGED HETEROCYCLIC COMPOUNDS
KARTON, YISHAI, FISHER, ABRAHAM, SHIRIN, AZRA, MESHULAM, HAIM, SEGALL, YOFFI
Year of Publication 01.10.1999
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Year of Publication 01.10.1999
Patent
Amyloid Precursor Protein Secretion via Muscarinic Receptors: Reduced Desensitization Using the M1-Selective Agonist AF102B
Haring, R., Gurwitz, D., Barg, J., Pinkaskramarski, R., Heldman, E., Pittel, Z., Wengier, A., Meshulam, H., Marciano, D., Karton, Y., Fisher, A.
Published in Biochemical and biophysical research communications (30.08.1994)
Published in Biochemical and biophysical research communications (30.08.1994)
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Journal Article
AZA SPIRO COMPOUNDS ACTING ON THE CHOLINERGIC SYSTEM WITH MUSCARINIC AGONIST ACTIVITY
MARCIANO, DANIELE, BARAK, DOV, FISHER, ABRAHAM, KARTON, YISHAL, MESHULAM, HAIM
Year of Publication 24.10.2006
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Year of Publication 24.10.2006
Patent
Rigid analogs of acetylcholine can be m1-selective agonists: implications for a rational treatment strategy in Alzheimer's disease
Fisher, Abraham, Gurwitz, David, Barak, Dov, Haring, Rachel, Karton, Ishai, Brandeis, Rachel, Pittel, Zipora, Marciano, Daniele, Meshulam, Haim, Vogel, Zvi, Heldman, Eliahu
Published in Bioorganic & medicinal chemistry letters (01.08.1992)
Published in Bioorganic & medicinal chemistry letters (01.08.1992)
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Journal Article
Menetelmä atsa-spiroyhdisteiden ja niiden enantiomeerien valmistamiseksi
MARCIANO,DANIELE, FISHER,ABRAHAM, KARTON,YISHAL, MESHULAM,HAIM, BARAK,DOV
Year of Publication 15.06.2004
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Year of Publication 15.06.2004
Patent
COMPUESTOS AZA ESPIRO QUE ACTUAN SOBRE EL SISTEMA COLINERGICO CON ACTIVIDAD AGONISTA MUSCARINICA
MARCIANO, DANIELE, BARAK, DOV, FISHER, ABRAHAM, KARTON, YISHAL, MESHULAM, HAIM
Year of Publication 16.09.2002
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Year of Publication 16.09.2002
Patent
SPIRO-COMPOUNDS AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME
KARTON YISHAL, MESHULAM HAIM, FISHER ABRAHAM, BARAK DOV, MARCIANO DANIELE
Year of Publication 30.08.2002
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Year of Publication 30.08.2002
Patent
AUF DAS CHOLINERGE SYSTEM MIT MUSCARIN AGONISTICHER AKTIVITÄT WIRKENDE AZA-SPIRO-VERBINDUNGEN
MARCIANO, DANIELE, BARAK, DOV, FISHER, ABRAHAM, KARTON, YISHAL, MESHULAM, HAIM
Year of Publication 29.08.2002
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Year of Publication 29.08.2002
Patent