Search Results - "MERTSCHING ELISABETH" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Serum-circulating His-tRNA synthetase inhibits organ-targeted immune responses

Serum-circulating His-tRNA synthetase inhibits organ-targeted immune responses

by Adams, Ryan A., Fernandes-Cerqueira, Cátia, Notarnicola, Antonella, Mertsching, Elisabeth, Xu, Zhiwen, Lo, Wing-Sze, Ogilvie, Kathleen, Chiang, Kyle P., Ampudia, Jeanette, Rosengren, Sanna, Cubitt, Andrea, King, David J., Mendlein, John D., Yang, Xiang-Lei, Nangle, Leslie A., Lundberg, Ingrid E., Jakobsson, Per-Johan, Schimmel, Paul
Published in Cellular & molecular immunology (01.06.2021)

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Caspase‐8 Variant G Regulates Rheumatoid Arthritis Fibroblast‐Like Synoviocyte Aggressive Behavior

Caspase‐8 Variant G Regulates Rheumatoid Arthritis Fibroblast‐Like Synoviocyte Aggressive Behavior

by Ansalone, Cecilia, Ainsworth, Richard I., Nygaard, Gyrid, Ai, Rizi, Prideaux, Edward B., Hammaker, Deepa, Perumal, Narayanan B., Weichert, Ken, Tung, Frances, Kodandapani, Lalitha, Sauder, J. Michael, Mertsching, Elisabeth C., Benschop, Robert J., Boyle, David L., Wang, Wei, Firestein, Gary S.
Published in ACR open rheumatology (01.04.2022)

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A mouse Fcγ-Fcϵ protein that inhibits mast cells through activation of FcγRIIB, SH2 domain–containing inositol phosphatase 1, and SH2 domain–containing protein tyrosine phosphatases

A mouse Fcγ-Fcϵ protein that inhibits mast cells through activation of FcγRIIB, SH2 domain–containing inositol phosphatase 1, and SH2 domain–containing protein tyrosine phosphatases

by Mertsching, Elisabeth, PhD, Bafetti, Lisa, BS, Hess, Henry, PhD, Perper, Stuart, BS, Giza, Keith, BS, Allen, Lisa Chan, PhD, Negrou, Ella, BS, Hathaway, Karen, BS, Hopp, Jennifer, MS, Chung, Julie, BS, Perret, Daniel, MS, Shields, Michael, PhD, Saxon, Andrew, MD, Kehry, Marilyn R., PhD
Published in Journal of allergy and clinical immunology (2008)

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IL-7 transgenic mice: analysis of the role of IL-7 in the differentiation of thymocytes in vivo and in vitro

IL-7 transgenic mice: analysis of the role of IL-7 in the differentiation of thymocytes in vivo and in vitro

by Mertsching, E, Burdet, C, Ceredig, R
Published in International immunology (01.03.1995)

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A mouse strain defective for αβ versus γδ T cell lineage commitment

A mouse strain defective for αβ versus γδ T cell lineage commitment

by Mertsching, Elisabeth, Wurster, Andrea L., Katayama, Carol, Esko, Jeffrey, Ramsdell, Fred, Marth, Jamey D., Hedrick, Stephen M.
Published in International immunology (01.09.2002)

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Identification of novel liquid biopsy biomarker for monitoring the immune set point in both solid tumor and hematological malignancy patients

Identification of novel liquid biopsy biomarker for monitoring the immune set point in both solid tumor and hematological malignancy patients

by King, David John, Adams, Ryan, Nangle, Leslie, Mertsching, Elisabeth, Ogilvie, Kathy, Cubitt, Andrea, Mendlein, John
Published in Journal of clinical oncology (10.02.2018)

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Abstract 2728: Circulating levels of Resokine, a soluble modulator of the immune system, are upregulated in both experimental cancer models and in patients across multiple tumor types

Abstract 2728: Circulating levels of Resokine, a soluble modulator of the immune system, are upregulated in both experimental cancer models and in patients across multiple tumor types

by Adams, Ryan, Mertsching, Elisabeth, Nangle, Leslie, Ogilvie, Kathy, Crampton, Steven, Bruner, John, Tyler, Samantha, Rosengren, Sanna, Cubitt, Andrea, King, David, Mendlein, John
Published in Cancer research (Chicago, Ill.) (01.07.2018)

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Discovery of structural diverse reversible BTK inhibitors utilized to develop a novel in vivo CD69 and CD86 PK/PD mouse model

Discovery of structural diverse reversible BTK inhibitors utilized to develop a novel in vivo CD69 and CD86 PK/PD mouse model

by Vandeveer, George H., Arduini, Robert M., Baker, Darren P., Barry, Kevin, Bohnert, Tonika, Bowden-Verhoek, Jon K., Conlon, Patrick, Cullen, Patrick F., Guan, Bing, Jenkins, Tracy J., Liao, Shu-Yu, Lin, Lin, Liu, Yu-Ting, Marcotte, Douglas, Mertsching, Elisabeth, Metrick, Claire M., Negrou, Ella, Powell, Noel, Scott, Daniel, Silvian, Laura F., Hopkins, Brian T.
Published in Bioorganic & medicinal chemistry letters (15.01.2023)

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Identification of a T cell immunomodulatory domain in histidyl-tRNA synthetase

Identification of a T cell immunomodulatory domain in histidyl-tRNA synthetase

by Mertsching, Elisabeth C., Ampudia, Jeanette, Adams, Ryan, Rosengren, Sanna, Nangle, Leslie, Mendlein, John, Cubitt, Andrea, Ramsdell, Fred, Ogilvie, Kathy, King, David
Published in The Journal of immunology (1950) (01.05.2018)

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Optimization of novel reversible Bruton’s tyrosine kinase inhibitors identified using Tethering-fragment-based screens

Optimization of novel reversible Bruton’s tyrosine kinase inhibitors identified using Tethering-fragment-based screens

by Hopkins, Brian T., Bame, Eris, Bell, Noah, Bohnert, Tonika, Bowden-Verhoek, Jon K., Bui, Minna, Cancilla, Mark T., Conlon, Patrick, Cullen, Patrick, Erlanson, Daniel A., Fan, Junfa, Fuchs-Knotts, Tarra, Hansen, Stig, Heumann, Stacey, Jenkins, Tracy J., Marcotte, Douglas, McDowell, Bob, Mertsching, Elisabeth, Negrou, Ella, Otipoby, Kevin L., Poreci, Urjana, Romanowski, Michael J., Scott, Daniel, Silvian, Laura, Yang, Wenjin, Zhong, Min
Published in Bioorganic & medicinal chemistry (01.07.2019)

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Utilizing structure based drug design and metabolic soft spot identification to optimize the in vitro potency and in vivo pharmacokinetic properties leading to the discovery of novel reversible Bruton’s tyrosine kinase inhibitors

Utilizing structure based drug design and metabolic soft spot identification to optimize the in vitro potency and in vivo pharmacokinetic properties leading to the discovery of novel reversible Bruton’s tyrosine kinase inhibitors

by Hopkins, Brian T., Bame, Eris, Bell, Noah, Bohnert, Tonika, Bowden-Verhoek, Jon K., Bui, Minna, Cancilla, Mark T., Conlon, Patrick, Cullen, Patrick, Erlanson, Daniel A., Fan, Junfa, Fuchs-Knotts, Tarra, Hansen, Stig, Heumann, Stacey, Jenkins, Tracy J., Gua, Chuck, Liu, Ying, Liu, YuTing, Lulla, Mukush, Marcotte, Douglas, Marx, Isaac, McDowell, Bob, Mertsching, Elisabeth, Negrou, Ella, Romanowski, Michael J., Scott, Daniel, Silvian, Laura, Yang, Wenjin, Zhong, Min
Published in Bioorganic & medicinal chemistry (15.08.2021)

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Structures of human Bruton's tyrosine kinase in active and inactive conformations suggest a mechanism of activation for TEC family kinases

Structures of human Bruton's tyrosine kinase in active and inactive conformations suggest a mechanism of activation for TEC family kinases

by Marcotte, Douglas J., Liu, Yu‐Ting, Arduini, Robert M., Hession, Catherine A., Miatkowski, Konrad, Wildes, Craig P., Cullen, Patrick F., Hong, Victor, Hopkins, Brian T., Mertsching, Elisabeth, Jenkins, Tracy J., Romanowski, Michael J., Baker, Darren P., Silvian, Laura F.
Published in Protein science (01.03.2010)

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An Intermediate pH Unfolding Transition Abrogates the Ability of IgE to Interact with Its High Affinity Receptor FcϵRIα

An Intermediate pH Unfolding Transition Abrogates the Ability of IgE to Interact with Its High Affinity Receptor FcϵRIα

by Demarest, Stephen J., Hopp, Jennifer, Chung, Julie, Hathaway, Karen, Mertsching, Elisabeth, Cao, Xianjun, George, Judy, Miatkowski, Konrad, LaBarre, Michael J., Shields, Michael, Kehry, Marilyn R.
Published in The Journal of biological chemistry (13.10.2006)

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Systemic administration of an Fcγ–Fcε-fusion protein in house dust mite sensitive nonhuman primates

Systemic administration of an Fcγ–Fcε-fusion protein in house dust mite sensitive nonhuman primates

by Van Scott, Michael R, Mertsching, Elisabeth, Negrou, Ella, Miles, Jeremy, Stallings, Howard W, Graff, Candace, Kehry, Marilyn R
Published in Clinical immunology (Orlando, Fla.) (01.09.2008)

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Mechanisms of allergy and clinical immunology: A mouse Fc gamma -Fc epsilon protein that inhibits mast cells through activation of Fc gamma RIIB, SH2 domain-containing inositol phosphatase 1, and SH2 domain-containing protein tyrosine phosphatases

Mechanisms of allergy and clinical immunology: A mouse Fc gamma -Fc epsilon protein that inhibits mast cells through activation of Fc gamma RIIB, SH2 domain-containing inositol phosphatase 1, and SH2 domain-containing protein tyrosine phosphatases

by Mertsching, Elisabeth, Bafetti, Lisa, Hess, Henry, Perper, Stuart, Giza, Keith, Allen, Lisa Chan, Negrou, Ella, Hathaway, Karen, Hopp, Jennifer, Chung, Julie, Perret, Daniel, Shields, Michael, Saxon, Andrew, Kehry, Marilyn R
Published in Journal of allergy and clinical immunology (01.02.2008)

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A mouse Fc[gamma]-Fc[epsilon] protein that inhibits mast cells through activation of Fc[gamma]RIIB, SH2 domain-containing inositol phosphatase 1, and SH2 domain-containing protein tyrosine phosphatases

A mouse Fc[gamma]-Fc[epsilon] protein that inhibits mast cells through activation of Fc[gamma]RIIB, SH2 domain-containing inositol phosphatase 1, and SH2 domain-containing protein tyrosine phosphatases

by Mertsching, Elisabeth, Bafetti, Lisa, Hess, Henry, Perper, Stuart, Giza, Keith, Allen, Lisa Chan, Negrou, Ella, Hathaway, Karen, Hopp, Jennifer, Chung, Julie, Perret, Daniel, Shields, Michael, Saxon, Andrew, Kehry, Marilyn R
Published in Journal of allergy and clinical immunology (01.02.2008)

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A mouse Fcγ-Fc∈ protein that inhibits mast cells through activation of FcγRIIB, SH2 domain-containing inositol phosphatase 1, and SH2 domain-containing protein tyrosine phosphatases

A mouse Fcγ-Fc∈ protein that inhibits mast cells through activation of FcγRIIB, SH2 domain-containing inositol phosphatase 1, and SH2 domain-containing protein tyrosine phosphatases

by MERTSCHING, Elisabeth, BAFETTI, Lisa, PERRET, Daniel, SHIELDS, Michael, SAXON, Andrew, KEHRY, Marilyn R, HESS, Henry, PERPER, Stuart, GIZA, Keith, CHAN ALLEN, Lisa, NEGROU, Ella, HATHAWAY, Karen, HOPP, Jennifer, CHUNG, Julie
Published in Journal of allergy and clinical immunology (2008)

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An Intermediate pH Unfolding Transition Abrogates the Ability of IgE to Interact with Its High Affinity Receptor FcÏµRIÎ

An Intermediate pH Unfolding Transition Abrogates the Ability of IgE to Interact with Its High Affinity Receptor FcÏµRIÎ

by Stephen J. Demarest, Jennifer Hopp, Julie Chung, Karen Hathaway, Elisabeth Mertsching, Xianjun Cao, Judy George, Konrad Miatkowski, Michael J. LaBarre, Michael Shields, Marilyn R. Kehry
Published in The Journal of biological chemistry (13.10.2006)

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An intermediate pH unfolding transition abrogates the ability of IgE to interact with its high affinity receptor FcepsilonRIalpha

An intermediate pH unfolding transition abrogates the ability of IgE to interact with its high affinity receptor FcepsilonRIalpha

by Demarest, Stephen J, Hopp, Jennifer, Chung, Julie, Hathaway, Karen, Mertsching, Elisabeth, Cao, Xianjun, George, Judy, Miatkowski, Konrad, LaBarre, Michael J, Shields, Michael, Kehry, Marilyn R
Published in The Journal of biological chemistry (13.10.2006)

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Phenotypic and functional analysis of B lymphopoiesis in interleukin-7-transgenic mice: expansion of pro/pre-B cell number and persistence of B lymphocyte development in lymph nodes and spleen

Phenotypic and functional analysis of B lymphopoiesis in interleukin-7-transgenic mice: expansion of pro/pre-B cell number and persistence of B lymphocyte development in lymph nodes and spleen

by Mertsching, E, Grawunder, U, Meyer, V, Rolink, T, Ceredig, R
Published in European journal of immunology (01.01.1996)

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