Venetoclax resistance and acquired BCL2 mutations in chronic lymphocytic leukemia
Tausch, Eugen, Close, William, Dolnik, Anna, Bloehdorn, Johannes, Chyla, Brenda, Bullinger, Lars, Döhner, Hartmut, Mertens, Daniel, Stilgenbauer, Stephan
Published in Haematologica (Roma) (01.09.2019)
Published in Haematologica (Roma) (01.09.2019)
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DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia
Oakes, Christopher C, Seifert, Marc, Assenov, Yassen, Gu, Lei, Przekopowitz, Martina, Ruppert, Amy S, Wang, Qi, Imbusch, Charles D, Serva, Andrius, Koser, Sandra D, Brocks, David, Lipka, Daniel B, Bogatyrova, Olga, Weichenhan, Dieter, Brors, Benedikt, Rassenti, Laura, Kipps, Thomas J, Mertens, Daniel, Zapatka, Marc, Lichter, Peter, Döhner, Hartmut, Küppers, Ralf, Zenz, Thorsten, Stilgenbauer, Stephan, Byrd, John C, Plass, Christoph
Published in Nature genetics (01.03.2016)
Published in Nature genetics (01.03.2016)
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Detailed analysis of p53 pathway defects in fludarabine-refractory chronic lymphocytic leukemia (CLL): dissecting the contribution of 17p deletion, TP53 mutation, p53-p21 dysfunction, and miR34a in a prospective clinical trial
Zenz, Thorsten, Häbe, Sonja, Denzel, Tina, Mohr, Julia, Winkler, Dirk, Bühler, Andreas, Sarno, Antonio, Groner, Silja, Mertens, Daniel, Busch, Raymonde, Hallek, Michael, Döhner, Hartmut, Stilgenbauer, Stephan
Published in Blood (24.09.2009)
Published in Blood (24.09.2009)
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Clonal evolution in chronic lymphocytic leukemia is scant in relapsed but accelerated in refractory cases after chemo(immune) therapy
Zapatka, Marc, Tausch, Eugen, Öztürk, Selcen, Yosifov, Deyan Yordanov, Seiffert, Martina, Zenz, Thorsten, Schneider, Christof, Blöhdorn, Johannes, Döhner, Hartmut, Mertens, Daniel, Lichter, Peter, Stilgenbauer, Stephan
Published in Haematologica (Roma) (01.03.2022)
Published in Haematologica (Roma) (01.03.2022)
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From Biology to Therapy: The CLL Success Story
Yosifov, Deyan Y., Wolf, Christine, Stilgenbauer, Stephan, Mertens, Daniel
Published in HemaSphere (01.04.2019)
Published in HemaSphere (01.04.2019)
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High-resolution genomic profiling of chronic lymphocytic leukemia reveals new recurrent genomic alterations
Edelmann, Jennifer, Holzmann, Karlheinz, Miller, Florian, Winkler, Dirk, Bühler, Andreas, Zenz, Thorsten, Bullinger, Lars, Kühn, Michael W.M., Gerhardinger, Andreas, Bloehdorn, Johannes, Radtke, Ina, Su, Xiaoping, Ma, Jing, Pounds, Stanley, Hallek, Michael, Lichter, Peter, Korbel, Jan, Busch, Raymonde, Mertens, Daniel, Downing, James R., Stilgenbauer, Stephan, Döhner, Hartmut
Published in Blood (06.12.2012)
Published in Blood (06.12.2012)
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miR-34a as part of the resistance network in chronic lymphocytic leukemia
Zenz, Thorsten, Mohr, Julia, Eldering, Eric, Kater, Arnon P., Bühler, Andreas, Kienle, Dirk, Winkler, Dirk, Dürig, Jan, van Oers, Marinus H.J., Mertens, Daniel, Döhner, Hartmut, Stilgenbauer, Stephan
Published in Blood (16.04.2009)
Published in Blood (16.04.2009)
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Epigenetic upregulation of lncRNAs at 13q14.3 in leukemia is linked to the In Cis downregulation of a gene cluster that targets NF-kB
Garding, Angela, Bhattacharya, Nupur, Claus, Rainer, Ruppel, Melanie, Tschuch, Cordula, Filarsky, Katharina, Idler, Irina, Zucknick, Manuela, Caudron-Herger, Maïwen, Oakes, Christopher, Fleig, Verena, Keklikoglou, Ioanna, Allegra, Danilo, Serra, Leticia, Thakurela, Sudhir, Tiwari, Vijay, Weichenhan, Dieter, Benner, Axel, Radlwimmer, Bernhard, Zentgraf, Hanswalter, Wiemann, Stefan, Rippe, Karsten, Plass, Christoph, Döhner, Hartmut, Lichter, Peter, Stilgenbauer, Stephan, Mertens, Daniel
Published in PLoS genetics (01.04.2013)
Published in PLoS genetics (01.04.2013)
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Evolution of DNA methylation is linked to genetic aberrations in chronic lymphocytic leukemia
Oakes, Christopher C, Claus, Rainer, Gu, Lei, Assenov, Yassen, Hüllein, Jennifer, Zucknick, Manuela, Bieg, Matthias, Brocks, David, Bogatyrova, Olga, Schmidt, Christopher R, Rassenti, Laura, Kipps, Thomas J, Mertens, Daniel, Lichter, Peter, Döhner, Hartmut, Stilgenbauer, Stephan, Byrd, John C, Zenz, Thorsten, Plass, Christoph
Published in Cancer discovery (01.03.2014)
Published in Cancer discovery (01.03.2014)
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Multi-platform profiling characterizes molecular subgroups and resistance networks in chronic lymphocytic leukemia
Bloehdorn, Johannes, Braun, Andrejs, Taylor-Weiner, Amaro, Jebaraj, Billy Michael Chelliah, Robrecht, Sandra, Krzykalla, Julia, Pan, Heng, Giza, Adam, Akylzhanova, Gulnara, Holzmann, Karlheinz, Scheffold, Annika, Johnston, Harvey E., Yeh, Ru-Fang, Klymenko, Tetyana, Tausch, Eugen, Eichhorst, Barbara, Bullinger, Lars, Fischer, Kirsten, Weisser, Martin, Robak, Tadeusz, Schneider, Christof, Gribben, John, Dahal, Lekh N., Carter, Mathew J., Elemento, Olivier, Landau, Dan A., Neuberg, Donna S., Cragg, Mark S., Benner, Axel, Hallek, Michael, Wu, Catherine J., Döhner, Hartmut, Stilgenbauer, Stephan, Mertens, Daniel
Published in Nature communications (13.09.2021)
Published in Nature communications (13.09.2021)
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Genomic alterations in high-risk chronic lymphocytic leukemia frequently affect cell cycle key regulators and NOTCH1-regulated transcription
Edelmann, Jennifer, Holzmann, Karlheinz, Tausch, Eugen, Saunderson, Emily A, Jebaraj, Billy M C, Steinbrecher, Daniela, Dolnik, Anna, Blätte, Tamara J, Landau, Dan A, Saub, Jenny, Estenfelder, Sven, Ibach, Stefan, Cymbalista, Florence, Leblond, Veronique, Delmer, Alain, Bahlo, Jasmin, Robrecht, Sandra, Fischer, Kirsten, Goede, Valentin, Bullinger, Lars, Wu, Catherine J, Mertens, Daniel, Ficz, Gabriella, Gribben, John G, Hallek, Michael, Döhner, Hartmut, Stilgenbauer, Stephan
Published in Haematologica (Roma) (01.05.2020)
Published in Haematologica (Roma) (01.05.2020)
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Hydroxylation of the NOTCH1 intracellular domain regulates Notch signaling dynamics
Ferrante, Francesca, Giaimo, Benedetto Daniele, Friedrich, Tobias, Sugino, Toshiya, Mertens, Daniel, Kugler, Sabrina, Gahr, Bernd Martin, Just, Steffen, Pan, Leiling, Bartkuhn, Marek, Potente, Michael, Oswald, Franz, Borggrefe, Tilman
Published in Cell death & disease (12.07.2022)
Published in Cell death & disease (12.07.2022)
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Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks
Mallm, Jan‐Philipp, Iskar, Murat, Ishaque, Naveed, Klett, Lara C, Kugler, Sabrina J, Muino, Jose M, Teif, Vladimir B, Poos, Alexandra M, Großmann, Sebastian, Erdel, Fabian, Tavernari, Daniele, Koser, Sandra D, Schumacher, Sabrina, Brors, Benedikt, König, Rainer, Remondini, Daniel, Vingron, Martin, Stilgenbauer, Stephan, Lichter, Peter, Zapatka, Marc, Mertens, Daniel, Rippe, Karsten
Published in Molecular systems biology (01.05.2019)
Published in Molecular systems biology (01.05.2019)
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Integrative prognostic models predict long-term survival after immunochemotherapy in chronic lymphocytic leukemia patients
Bloehdorn, Johannes, Krzykalla, Julia, Holzmann, Karlheinz, Gerhardinger, Andreas, Jebaraj, Billy Michael Chelliah, Bahlo, Jasmin, Humphrey, Kathryn, Tausch, Eugen, Robrecht, Sandra, Mertens, Daniel, Schneider, Christof, Fischer, Kirsten, Hallek, Michael, Döhner, Hartmut, Benner, Axel, Stilgenbauer, Stephan
Published in Haematologica (Roma) (01.03.2022)
Published in Haematologica (Roma) (01.03.2022)
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Atypical enteropathogenic E. coli are associated with disease activity in ulcerative colitis
Baumgartner, Maximilian, Zirnbauer, Rebecca, Schlager, Sabine, Mertens, Daniel, Gasche, Nikolaus, Sladek, Barbara, Herbold, Craig, Bochkareva, Olga, Emelianenko, Vera, Vogelsang, Harald, Lang, Michaela, Klotz, Anton, Moik, Birgit, Makristathis, Athanasios, Berry, David, Dabsch, Stefanie, Khare, Vineeta, Gasche, Christoph
Published in Gut microbes (31.12.2022)
Published in Gut microbes (31.12.2022)
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Quantitative DNA Methylation Analysis Identifies a Single CpG Dinucleotide Important for ZAP-70 Expression and Predictive of Prognosis in Chronic Lymphocytic Leukemia
CLAUS, Rainer, LUCAS, David M, KAY, Neil E, JELINEK, Diane F, KIPPS, Thomas J, RASSENTI, Laura Z, GRIBBEN, John G, DÖHNER, Hartmut, HEEREMA, Nyla A, MARCUCCI, Guido, PLASS, Christoph, BYRD, John C, STILGENBAUER, Stephan, RUPPERT, Amy S, LIANBO YU, ZUCKNICK, Manuela, MERTENS, Daniel, BÜHLER, Andreas, OAKES, Christopher C, LARSON, Richard A
Published in Journal of clinical oncology (10.07.2012)
Published in Journal of clinical oncology (10.07.2012)
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Programmed death-1 and its ligand are novel immunotolerant molecules expressed on leukemic B cells in chronic lymphocytic leukemia
Grzywnowicz, Maciej, Zaleska, Joanna, Mertens, Daniel, Tomczak, Waldemar, Wlasiuk, Paulina, Kosior, Kamila, Piechnik, Agnieszka, Bojarska-Junak, Agnieszka, Dmoszynska, Anna, Giannopoulos, Krzysztof
Published in PloS one (19.04.2012)
Published in PloS one (19.04.2012)
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Predictive value of DNA methylation patterns in AML patients treated with an azacytidine containing induction regimen
Schmutz, Maximilian, Zucknick, Manuela, Schlenk, Richard F, Mertens, Daniel, Benner, Axel, Weichenhan, Dieter, Mücke, Oliver, Döhner, Konstanze, Plass, Christoph, Bullinger, Lars, Claus, Rainer
Published in Clinical epigenetics (26.10.2023)
Published in Clinical epigenetics (26.10.2023)
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