Novel functional M1 selective muscarinic agonists. 2. Synthesis and structure-activity relationships of 3-pyrazinyl-1,2,5,6-tetrahydro-1-methylpyridines. Construction of a molecular model for the M1 pharmacophore
Ward, John S, Merritt, Leander, Klimkowski, V. J, Lamb, M. L, Mitch, C. H, Bymaster, F. P, Sawyer, B, Shannon, H. E, Olesen, Preben H
Published in Journal of medicinal chemistry (01.10.1992)
Published in Journal of medicinal chemistry (01.10.1992)
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1,2,5-Thiadiazole Analogues of Aceclidine as Potent m1 Muscarinic Agonists
Ward, John S, Merritt, Leander, Calligaro, David O, Bymaster, Franklin P, Shannon, Harlan E, Mitch, Charles H, Whitesitt, Celia, Brunsting, David, Sheardown, Malcolm J, Olesen, Preben H, Swedberg, Michael D. B, Jeppesen, Lone, Sauerberg, Per
Published in Journal of medicinal chemistry (29.01.1998)
Published in Journal of medicinal chemistry (29.01.1998)
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Functionally selective M1 muscarinic agonists. 3. Side chains and azacycles contributing to functional muscarinic selectivity among pyrazinylazacycles
Ward, J S, Merritt, L, Calligaro, D O, Bymaster, F P, Shannon, H E, Sawyer, B D, Mitch, C H, Deeter, J B, Peters, S C, Sheardown, M J, Olesen, P H, Swedberg, M D, Sauerberg, P
Published in Journal of medicinal chemistry (01.09.1995)
Published in Journal of medicinal chemistry (01.09.1995)
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Journal Article
1,2,5-Thiadiazole Analogues of Aceclidine as Potent m 1 Muscarinic Agonists
Ward, John S., Merritt, Leander, Calligaro, David O., Bymaster, Franklin P., Shannon, Harlan E., Mitch, Charles H., Whitesitt, Celia, Brunsting, David, Sheardown, Malcolm J., Olesen, Preben H., Swedberg, Michael D. B., Jeppesen, Lone, Sauerberg, Per
Published in Journal of medicinal chemistry (01.01.1998)
Published in Journal of medicinal chemistry (01.01.1998)
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Journal Article