Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD
Fang, Mark Y., Markmiller, Sebastian, Vu, Anthony Q., Javaherian, Ashkan, Dowdle, William E., Jolivet, Philippe, Bushway, Paul J., Castello, Nicholas A., Baral, Ashmita, Chan, Michelle Y., Linsley, Jeremy W., Linsley, Drew, Mercola, Mark, Finkbeiner, Steven, Lecuyer, Eric, Lewcock, Joseph W., Yeo, Gene W.
Published in Neuron (Cambridge, Mass.) (04.09.2019)
Published in Neuron (Cambridge, Mass.) (04.09.2019)
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Use of human induced pluripotent stem cell–derived cardiomyocytes to assess drug cardiotoxicity
Sharma, Arun, McKeithan, Wesley L., Serrano, Ricardo, Kitani, Tomoya, Burridge, Paul W., del Álamo, Juan C., Mercola, Mark, Wu, Joseph C.
Published in Nature protocols (01.12.2018)
Published in Nature protocols (01.12.2018)
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Cardiac muscle regeneration: lessons from development
Mercola, Mark, Ruiz-Lozano, Pilar, Schneider, Michael D
Published in Genes & development (15.02.2011)
Published in Genes & development (15.02.2011)
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Epicardial FSTL1 reconstitution regenerates the adult mammalian heart
Wei, Ke, Serpooshan, Vahid, Hurtado, Cecilia, Diez-Cuñado, Marta, Zhao, Mingming, Maruyama, Sonomi, Zhu, Wenhong, Fajardo, Giovanni, Noseda, Michela, Nakamura, Kazuto, Tian, Xueying, Liu, Qiaozhen, Wang, Andrew, Matsuura, Yuka, Bushway, Paul, Cai, Wenqing, Savchenko, Alex, Mahmoudi, Morteza, Schneider, Michael D., van den Hoff, Maurice J. B., Butte, Manish J., Yang, Phillip C., Walsh, Kenneth, Zhou, Bin, Bernstein, Daniel, Mercola, Mark, Ruiz-Lozano, Pilar
Published in Nature (London) (24.09.2015)
Published in Nature (London) (24.09.2015)
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Inhibition of miR-25 improves cardiac contractility in the failing heart
Wahlquist, Christine, Jeong, Dongtak, Rojas-Muñoz, Agustin, Kho, Changwon, Lee, Ahyoung, Mitsuyama, Shinichi, van Mil, Alain, Jin Park, Woo, Sluijter, Joost P. G., Doevendans, Pieter A. F., Hajjar, Roger J., Mercola, Mark
Published in Nature (London) (24.04.2014)
Published in Nature (London) (24.04.2014)
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Small-Molecule Inhibitors of the Wnt Pathway Potently Promote Cardiomyocytes From Human Embryonic Stem Cell–Derived Mesoderm
Willems, Erik, Spiering, Sean, Davidovics, Herman, Lanier, Marion, Xia, Zebin, Dawson, Marcia, Cashman, John, Mercola, Mark
Published in Circulation research (05.08.2011)
Published in Circulation research (05.08.2011)
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A Premature Termination Codon Mutation in MYBPC3 Causes Hypertrophic Cardiomyopathy via Chronic Activation of Nonsense-Mediated Decay
Seeger, Timon, Shrestha, Rajani, Lam, Chi Keung, Chen, Caressa, McKeithan, Wesley L, Lau, Edward, Wnorowski, Alexa, McMullen, George, Greenhaw, Matthew, Lee, Jaecheol, Oikonomopoulos, Angelos, Lee, Soah, Yang, Huaxiao, Mercola, Mark, Wheeler, Matthew, Ashley, Euan A, Yang, Fan, Karakikes, Ioannis, Wu, Joseph C
Published in Circulation (New York, N.Y.) (05.02.2019)
Published in Circulation (New York, N.Y.) (05.02.2019)
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APJ acts as a dual receptor in cardiac hypertrophy
Scimia, Maria Cecilia, Hurtado, Cecilia, Ray, Saugata, Metzler, Scott, Wei, Ke, Wang, Jianming, Woods, Chris E., Purcell, Nicole H., Catalucci, Daniele, Akasaka, Takeshi, Bueno, Orlando F., Vlasuk, George P., Kaliman, Perla, Bodmer, Rolf, Smith, Layton H., Ashley, Euan, Mercola, Mark, Brown, Joan Heller, Ruiz-Lozano, Pilar
Published in Nature (London) (16.08.2012)
Published in Nature (London) (16.08.2012)
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Fine-Tuning of Drp1/Fis1 Availability by AKAP121/Siah2 Regulates Mitochondrial Adaptation to Hypoxia
Kim, Hyungsoo, Scimia, Maria C., Wilkinson, Deepti, Trelles, Ramon D., Wood, Malcolm R., Bowtell, David, Dillin, Andrew, Mercola, Mark, Ronai, Ze'ev A.
Published in Molecular cell (18.11.2011)
Published in Molecular cell (18.11.2011)
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Technical Variations in Low-Input RNA-seq Methodologies
Bhargava, Vipul, Head, Steven R., Ordoukhanian, Phillip, Mercola, Mark, Subramaniam, Shankar
Published in Scientific reports (14.01.2014)
Published in Scientific reports (14.01.2014)
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Unfolded Protein Response as a Compensatory Mechanism and Potential Therapeutic Target in PLN R14del Cardiomyopathy
Feyen, Dries A.M., Perea-Gil, Isaac, Maas, Renee G.C., Harakalova, Magdalena, Gavidia, Alexandra A., Arthur Ataam, Jennifer, Wu, Ting-Hsuan, Vink, Aryan, Pei, Jiayi, Vadgama, Nirmal, Suurmeijer, Albert J., te Rijdt, Wouter P., Vu, Michelle, Amatya, Prashila L., Prado, Maricela, Zhang, Yuan, Dunkenberger, Logan, Sluijter, Joost P.G., Sallam, Karim, Asselbergs, Folkert W., Mercola, Mark, Karakikes, Ioannis
Published in Circulation (New York, N.Y.) (03.08.2021)
Published in Circulation (New York, N.Y.) (03.08.2021)
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miR-322/-503 cluster is expressed in the earliest cardiac progenitor cells and drives cardiomyocyte specification
Shen, Xiaopeng, Soibam, Benjamin, Benham, Ashley, Xu, Xueping, Chopra, Mani, Peng, Xiaoping, Yu, Wei, Bao, Wenjing, Liang, Rui, Azares, Alon, Liu, Peijun, Gunaratne, Preethi H., Mercola, Mark, Cooney, Austin J., Schwartz, Robert J., Liu, Yu
Published in Proceedings of the National Academy of Sciences - PNAS (23.08.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (23.08.2016)
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HDAC-regulated myomiRs control BAF60 variant exchange and direct the functional phenotype of fibro-adipogenic progenitors in dystrophic muscles
Saccone, Valentina, Consalvi, Silvia, Giordani, Lorenzo, Mozzetta, Chiara, Barozzi, Iros, Sandoná, Martina, Ryan, Tammy, Rojas-Muñoz, Agustin, Madaro, Luca, Fasanaro, Pasquale, Borsellino, Giovanna, De Bardi, Marco, Frigè, Gianmaria, Termanini, Alberto, Sun, Xin, Rossant, Janet, Bruneau, Benoit G, Mercola, Mark, Minucci, Saverio, Puri, Pier Lorenzo
Published in Genes & development (15.04.2014)
Published in Genes & development (15.04.2014)
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Transcription factors ETS2 and MESP1 transdifferentiate human dermal fibroblasts into cardiac progenitors
Islas, Jose Francisco, Liu, Yu, Weng, Kuo-Chan, Robertson, Matthew J, Zhang, Shuxing, Prejusa, Allan, Harger, John, Tikhomirova, Dariya, Chopra, Mani, Iyer, Dinakar, Mercola, Mark, Oshima, Robert G, Willerson, James T, Potaman, Vladimir N, Schwartz, Robert J
Published in Proceedings of the National Academy of Sciences - PNAS (07.08.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (07.08.2012)
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Disruption of NOTCH signaling by a small molecule inhibitor of the transcription factor RBPJ
Hurtado, Cecilia, Safarova, Alena, Smith, Michael, Chung, Raeeun, Bruyneel, Arne A. N., Gomez-Galeno, Jorge, Oswald, Franz, Larson, Christopher J., Cashman, John R., Ruiz-Lozano, Pilar, Janiak, Philip, Suzuki, Teri, Mercola, Mark
Published in Scientific reports (25.07.2019)
Published in Scientific reports (25.07.2019)
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A Novel Recessive Mutation in SPEG Causes Early Onset Dilated Cardiomyopathy
Levitas, Aviva, Muhammad, Emad, Zhang, Yuan, Perea Gil, Isaac, Serrano, Ricardo, Diaz, Nashielli, Arafat, Maram, Gavidia, Alexandra A, Kapiloff, Michael S, Mercola, Mark, Etzion, Yoram, Parvari, Ruti, Karakikes, Ioannis
Published in PLoS genetics (14.09.2020)
Published in PLoS genetics (14.09.2020)
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Reengineering an Antiarrhythmic Drug Using Patient hiPSC Cardiomyocytes to Improve Therapeutic Potential and Reduce Toxicity
McKeithan, Wesley L., Feyen, Dries A.M., Bruyneel, Arne A.N., Okolotowicz, Karl J., Ryan, Daniel A., Sampson, Kevin J., Potet, Franck, Savchenko, Alex, Gómez-Galeno, Jorge, Vu, Michelle, Serrano, Ricardo, George, Alfred L., Kass, Robert S., Cashman, John R., Mercola, Mark
Published in Cell stem cell (05.11.2020)
Published in Cell stem cell (05.11.2020)
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