Deconstructing the Peptide-MHC Specificity of T Cell Recognition
Birnbaum, Michael E., Mendoza, Juan L., Sethi, Dhruv K., Dong, Shen, Glanville, Jacob, Dobbins, Jessica, Özkan, Engin, Davis, Mark M., Wucherpfennig, Kai W., Garcia, K. Christopher
Published in Cell (22.05.2014)
Published in Cell (22.05.2014)
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Journal Article
Alpha and Beta Type 1 Interferon Signaling: Passage for Diverse Biologic Outcomes
Ng, Cherie T., Mendoza, Juan L., Garcia, K. Christopher, Oldstone, Michael B.A.
Published in Cell (28.01.2016)
Published in Cell (28.01.2016)
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Journal Article
Requirements for Efficient Correction of ΔF508 CFTR Revealed by Analyses of Evolved Sequences
Mendoza, Juan L., Schmidt, André, Li, Qin, Nuvaga, Emmanuel, Barrett, Tyler, Bridges, Robert J., Feranchak, Andrew P., Brautigam, Chad A., Thomas, Philip J.
Published in Cell (20.01.2012)
Published in Cell (20.01.2012)
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Journal Article
Differential induction of interferon stimulated genes between type I and type III interferons is independent of interferon receptor abundance
Pervolaraki, Kalliopi, Rastgou Talemi, Soheil, Albrecht, Dorothee, Bormann, Felix, Bamford, Connor, Mendoza, Juan L, Garcia, K Christopher, McLauchlan, John, Höfer, Thomas, Stanifer, Megan L, Boulant, Steeve
Published in PLoS pathogens (01.11.2018)
Published in PLoS pathogens (01.11.2018)
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Journal Article
HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome
Illing, Patricia T., Pymm, Phillip, Croft, Nathan P., Hilton, Hugo G., Jojic, Vladimir, Han, Alex S., Mendoza, Juan L., Mifsud, Nicole A., Dudek, Nadine L., McCluskey, James, Parham, Peter, Rossjohn, Jamie, Vivian, Julian P., Purcell, Anthony W.
Published in Nature communications (08.11.2018)
Published in Nature communications (08.11.2018)
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Journal Article
Synthekines are surrogate cytokine and growth factor agonists that compel signaling through non-natural receptor dimers
Moraga, Ignacio, Spangler, Jamie B, Mendoza, Juan L, Gakovic, Milica, Wehrman, Tom S, Krutzik, Peter, Garcia, K Christopher
Published in eLife (12.05.2017)
Published in eLife (12.05.2017)
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Journal Article
A polymorphic residue that attenuates the antiviral potential of interferon lambda 4 in hominid lineages
Bamford, Connor G G, Aranday-Cortes, Elihu, Filipe, Ines Cordeiro, Sukumar, Swathi, Mair, Daniel, Filipe, Ana da Silva, Mendoza, Juan L, Garcia, K Christopher, Fan, Shaohua, Tishkoff, Sarah A, McLauchlan, John
Published in PLoS pathogens (01.10.2018)
Published in PLoS pathogens (01.10.2018)
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Journal Article
The Intergenic Recombinant HLA-B∗46:01 Has a Distinctive Peptidome that Includes KIR2DL3 Ligands
Hilton, Hugo G., McMurtrey, Curtis P., Han, Alex S., Djaoud, Zakia, Guethlein, Lisbeth A., Blokhuis, Jeroen H., Pugh, Jason L., Goyos, Ana, Horowitz, Amir, Buchli, Rico, Jackson, Ken W., Bardet, Wilfred, Bushnell, David A., Robinson, Philip J., Mendoza, Juan L., Birnbaum, Michael E., Nielsen, Morten, Garcia, K. Christopher, Hildebrand, William H., Parham, Peter
Published in Cell reports (Cambridge) (16.05.2017)
Published in Cell reports (Cambridge) (16.05.2017)
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Journal Article
Interrogating the recognition landscape of a conserved HIV-specific TCR reveals distinct bacterial peptide cross-reactivity
Mendoza, Juan L, Fischer, Suzanne, Gee, Marvin H, Lam, Lilian H, Brackenridge, Simon, Powrie, Fiona M, Birnbaum, Michael, McMichael, Andrew J, Garcia, K Christopher, Gillespie, Geraldine M
Published in eLife (27.07.2020)
Published in eLife (27.07.2020)
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Journal Article
Insights into Cytokine-Receptor Interactions from Cytokine Engineering
Spangler, Jamie B, Moraga, Ignacio, Mendoza, Juan L, Garcia, K. Christopher
Published in Annual review of immunology (01.01.2015)
Published in Annual review of immunology (01.01.2015)
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Journal Article
Outcomes of Medical and Surgical Therapy for Entero-urinary Fistulas in Crohn’s Disease
Taxonera, Carlos, Barreiro-de-Acosta, Manuel, Bastida, Guillermo, Martinez-Gonzalez, Javier, Merino, Olga, García-Sánchez, Valle, Gisbert, Javier P., Marín-Jiménez, Ignacio, López-Serrano, Pilar, Gómez-García, María, Iglesias, Eva, Lopez-Sanroman, Antonio, Chaparro, María, Saro, Cristina, Bermejo, Fernando, Pérez-Carazo, Leticia, Plaza, Rocio, Olivares, David, Alba, Cristina, Mendoza, Juan L., Fernández-Blanco, Ignacio
Published in Journal of Crohn's and colitis (01.06.2016)
Published in Journal of Crohn's and colitis (01.06.2016)
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Journal Article
Interferons and viruses induce a novel truncated ACE2 isoform and not the full-length SARS-CoV-2 receptor
Onabajo, Olusegun O., Banday, A. Rouf, Stanifer, Megan L., Yan, Wusheng, Obajemu, Adeola, Santer, Deanna M., Florez-Vargas, Oscar, Piontkivska, Helen, Vargas, Joselin M., Ring, Timothy J., Kee, Carmon, Doldan, Patricio, Tyrrell, D. Lorne, Mendoza, Juan L., Boulant, Steeve, Prokunina-Olsson, Ludmila
Published in Nature genetics (01.12.2020)
Published in Nature genetics (01.12.2020)
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Journal Article
Structure of the IFNγ receptor complex guides design of biased agonists
Mendoza, Juan L., Escalante, Nichole K., Jude, Kevin M., Sotolongo Bellon, Junel, Su, Leon, Horton, Tim M., Tsutsumi, Naotaka, Berardinelli, Steven J., Haltiwanger, Robert S., Piehler, Jacob, Engleman, Edgar G., Garcia, K. Christopher
Published in Nature (London) (07.03.2019)
Published in Nature (London) (07.03.2019)
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Journal Article
Antigen Identification for Orphan T Cell Receptors Expressed on Tumor-Infiltrating Lymphocytes
Gee, Marvin H., Han, Arnold, Lofgren, Shane M., Beausang, John F., Mendoza, Juan L., Birnbaum, Michael E., Bethune, Michael T., Fischer, Suzanne, Yang, Xinbo, Gomez-Eerland, Raquel, Bingham, David B., Sibener, Leah V., Fernandes, Ricardo A., Velasco, Andrew, Baltimore, David, Schumacher, Ton N., Khatri, Purvesh, Quake, Stephen R., Davis, Mark M., Garcia, K. Christopher
Published in Cell (25.01.2018)
Published in Cell (25.01.2018)
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Journal Article
Structure–function of type I and III interferons
de Weerd, Nicole A, Kurowska, Aleksandra K, Mendoza, Juan L, Schreiber, Gideon
Published in Current opinion in immunology (01.02.2024)
Published in Current opinion in immunology (01.02.2024)
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Journal Article
Water and Ligand Entry in Myoglobin: Assessing the Speed and Extent of Heme Pocket Hydration after CO Photodissociation
Goldbeck, Robert A., Bhaskaran, Shyam, Ortega, Cheri, Mendoza, Juan L., Olson, John S., Soman, Jayashree, Kliger, David S., Esquerra, Raymond M.
Published in Proceedings of the National Academy of Sciences - PNAS (31.01.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (31.01.2006)
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Journal Article
T cell receptor cross-reactivity expanded by dramatic peptide–MHC adaptability
Riley, Timothy P., Hellman, Lance M., Gee, Marvin H., Mendoza, Juan L., Alonso, Jesus A., Foley, Kendra C., Nishimura, Michael I., Vander Kooi, Craig W., Garcia, K. Christopher, Baker, Brian M.
Published in Nature chemical biology (01.10.2018)
Published in Nature chemical biology (01.10.2018)
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Journal Article
The IFN-λ-IFN-λR1-IL-10Rβ Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity
Mendoza, Juan L., Schneider, William M., Hoffmann, Hans-Heinrich, Vercauteren, Koen, Jude, Kevin M., Xiong, Anming, Moraga, Ignacio, Horton, Tim M., Glenn, Jeffrey S., de Jong, Ype P., Rice, Charles M., Garcia, K. Christopher
Published in Immunity (Cambridge, Mass.) (21.03.2017)
Published in Immunity (Cambridge, Mass.) (21.03.2017)
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Journal Article