Pharmacology of AMG 416 (Velcalcetide), a novel peptide agonist of the calcium-sensing receptor, for the treatment of secondary hyperparathyroidism in hemodialysis patients
Walter, Sarah, Baruch, Amos, Dong, Jin, Tomlinson, James E, Alexander, Shawn T, Janes, Julie, Hunter, Tom, Yin, Qun, Maclean, Derek, Bell, Gregory, Mendel, Dirk B, Johnson, Randolph M, Karim, Felix
Published in The Journal of pharmacology and experimental therapeutics (01.08.2013)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2013)
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In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of a pharmacokinetic/pharmacodynamic relationship
MENDEL, Dirk B, LAIRD, A. Douglas, MURRAY, Lesley J, CARVER, Jeremy, CHAN, Emily, MOSS, Katherine G, HAZNEDAR, Joshua Ö, SUKBUNTHERNG, Juthamas, BLAKE, Robert A, LI SUN, CHO TANG, MILLER, Todd, XIAOHUA XIN, SHIRAZIAN, Sheri, MCMAHON, Gerald, CHERRINGTON, Julie M, LOUIE, Sharianne G, CHRISTENSEN, James G, GUANGMIN LI, SCHRECK, Randall E, ABRAMS, Tinya J, NGAI, Theresa J, LEE, Leslie B
Published in Clinical cancer research (2003)
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Published in Clinical cancer research (2003)
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A selective small molecule inhibitor of c-Met kinase inhibits c-met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo
CHRISTENSEN, James G, SCHRECK, Randall, LIPSON, Kenneth E, RAMPHAL, John, DO, Steven, CUI, Jingrong J, CHERRINGTON, Julie M, MENDEL, Dirk B, BURROWS, Jon, KURUGANTI, Poonam, CHAN, Emily, PHUONG LE, CHEN, Jeffrey, XUEYAN WANG, RUSLIM, Lany, BLAKE, Robert
Published in Cancer research (Chicago, Ill.) (01.11.2003)
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Published in Cancer research (Chicago, Ill.) (01.11.2003)
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Phase I Dose-Escalating Study of SU11654, a Small Molecule Receptor Tyrosine Kinase Inhibitor, in Dogs with Spontaneous Malignancies
LONDON, Cheryl A, HANNAH, Alison L, MENDEL, Dirk B, MCMAHON, Gerald, CHERRINGTON, Julie M, ZADOVOSKAYA, Regina, CHIEN, May B, KOLLIAS-BAKER, Cynthia, ROSENBERG, Mona, DOWNING, Sue, POST, Gerald, BOUCHER, Joseph, SHENOY, Narmada
Published in Clinical cancer research (01.07.2003)
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Published in Clinical cancer research (01.07.2003)
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Comparison of AMG 416 and cinacalcet in rodent models of uremia
Walter, Sarah, Baruch, Amos, Alexander, Shawn T, Janes, Julie, Sho, Eiketsu, Dong, Jin, Yin, Qun, Maclean, Derek, Mendel, Dirk B, Karim, Felix, Johnson, Randolph M
Published in BMC nephrology (19.05.2014)
Published in BMC nephrology (19.05.2014)
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Contribution of individual targets to the antitumor efficacy of the multitargeted receptor tyrosine kinase inhibitor SU11248
Potapova, Olga, Laird, A Douglas, Nannini, Michelle A, Barone, Angela, Li, Guangmin, Moss, Katherine G, Cherrington, Julie M, Mendel, Dirk B
Published in Molecular cancer therapeutics (01.05.2006)
Published in Molecular cancer therapeutics (01.05.2006)
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SU14813: a novel multiple receptor tyrosine kinase inhibitor with potent antiangiogenic and antitumor activity
Patyna, Shem, Laird, A Douglas, Mendel, Dirk B, O'farrell, Anne-Marie, Liang, Chris, Guan, Huiping, Vojkovsky, Tomas, Vasile, Stefan, Wang, Xueyan, Chen, Jeffrey, Grazzini, Maren, Yang, Cheng Y, Haznedar, Joshua O, Sukbuntherng, Juthamas, Zhong, Wei-Zhu, Cherrington, Julie M, Hu-Lowe, Dana
Published in Molecular cancer therapeutics (01.07.2006)
Published in Molecular cancer therapeutics (01.07.2006)
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CHIR-258 Is Efficacious in A Newly Developed Fibroblast Growth Factor Receptor 3–Expressing Orthotopic Multiple Myeloma Model in Mice
XIAOHUA XIN, ABRAMS, Tinya J, TRUDEL, Suzanne, JALLAL, Bahija, MENDEL, Dirk B, HEISE, Carla C, HOLLENBACH, Paul W, RENDAHL, Katherine G, YAN TANG, OEI, Yoko A, EMBRY, Millicent G, SWINARSKI, Debbie E, GARRETT, Evelyn N, PRYER, Nancy K
Published in Clinical cancer research (15.08.2006)
Published in Clinical cancer research (15.08.2006)
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Influenza Neuraminidase Inhibitors Possessing a Novel Hydrophobic Interaction in the Enzyme Active Site: Design, Synthesis, and Structural Analysis of Carbocyclic Sialic Acid Analogues with Potent Anti-Influenza Activity
Kim, Choung U, Lew, Willard, Williams, Matthew A, Liu, Hongtao, Zhang, Lijun, Swaminathan, S, Bischofberger, Norbert, Chen, Ming S, Mendel, Dirk B, Tai, Chun Y, Laver, W. Graeme, Stevens, Raymond C
Published in Journal of the American Chemical Society (29.01.1997)
Published in Journal of the American Chemical Society (29.01.1997)
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Translational sciences approach to RSV vaccine development
Kurzweil, Vanessa, Tang, Roderick, Galinski, Mark, Wang, Kathy, Zuo, Fengrong, Cherukuri, Anu, Gasser, Robert A, Malkin, Elissa, Sifakis, Frangiscos, Mendel, Dirk B, Esser, Mark T
Published in Expert review of vaccines (01.09.2013)
Published in Expert review of vaccines (01.09.2013)
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The Angiogenesis Inhibitor SU5416 Has Long-lasting Effects on Vascular Endothelial Growth Factor Receptor Phosphorylation and Function
MENDEL, Dirk B, SCHRECK, Randall E, WEST, David C, GUANGMIN LI, STRAWN, Laurie M, TANCIONGCO, Sheila S, VASILE, Stefan, SHAWVER, Laura K, CHERRINGTON, Julie M
Published in Clinical cancer research (01.12.2000)
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Published in Clinical cancer research (01.12.2000)
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Structure−Activity Relationship Studies of Novel Carbocyclic Influenza Neuraminidase Inhibitors
Kim, Choung U, Lew, Willard, Williams, Matthew A, Wu, Huiwei, Zhang, Lijun, Chen, Xiaowu, Escarpe, Paul A, Mendel, Dirk B, Laver, W. Graeme, Stevens, Raymond C
Published in Journal of medicinal chemistry (02.07.1998)
Published in Journal of medicinal chemistry (02.07.1998)
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Hair Depigmentation Is a Biological Readout for Pharmacological Inhibition of KIT in Mice and Humans
Moss, Katherine G, Toner, Guy C, Cherrington, Julie M, Mendel, Dirk B, Laird, A Douglas
Published in The Journal of pharmacology and experimental therapeutics (01.11.2003)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2003)
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Journal Article
Src family kinase activity is required for signal tranducer and activator of transcription 3 and focal adhesion kinase phosphorylation and vascular endothelial growth factor signaling in vivo and for anchorage-dependent and -independent growth of human tumor cells
Laird, A Douglas, Li, Guangmin, Moss, Katherine G, Blake, Robert A, Broome, Martin A, Cherrington, Julie M, Mendel, Dirk B
Published in Molecular cancer therapeutics (01.05.2003)
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Published in Molecular cancer therapeutics (01.05.2003)
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Novel Robust Hepatitis C Virus Mouse Efficacy Model
QING ZHU, OEI, Yoko, MENDEL, Dirk B, GARRETT, Evelyn N, PATAWARAN, Montesa B, HOLLENBACH, Paul W, AUKERMAN, Sharon L, WEINER, Amy J
Published in Antimicrobial Agents and Chemotherapy (01.10.2006)
Published in Antimicrobial Agents and Chemotherapy (01.10.2006)
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