Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice
Yue, M, Hinkle, K.M, Davies, P, Trushina, E, Fiesel, F.C, Christenson, T.A, Schroeder, A.S, Zhang, L, Bowles, E, Behrouz, B, Lincoln, S.J, Beevers, J.E, Milnerwood, A.J, Kurti, A, McLean, P.J, Fryer, J.D, Springer, W, Dickson, D.W, Farrer, M.J, Melrose, H.L
Published in Neurobiology of disease (01.06.2015)
Published in Neurobiology of disease (01.06.2015)
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Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice
Melrose, H.L, Dächsel, J.C, Behrouz, B, Lincoln, S.J, Yue, M, Hinkle, K.M, Kent, C.B, Korvatska, E, Taylor, J.P, Witten, L, Liang, Y.-Q, Beevers, J.E, Boules, M, Dugger, B.N, Serna, V.A, Gaukhman, A, Yu, X, Castanedes-Casey, M, Braithwaite, A.T, Ogholikhan, S, Yu, N, Bass, D, Tyndall, G, Schellenberg, G.D, Dickson, D.W, Janus, C, Farrer, M.J
Published in Neurobiology of disease (01.12.2010)
Published in Neurobiology of disease (01.12.2010)
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A comparative analysis of leucine-rich repeat kinase 2 (Lrrk2) expression in mouse brain and Lewy body disease
Melrose, H.L, Kent, C.B, Taylor, J.P, Dachsel, J.C, Hinkle, K.M, Lincoln, S.J, Mok, S.S, Culvenor, J.G, Masters, C.L, Tyndall, G.M, Bass, D.I, Ahmed, Z, Andorfer, C.A, Ross, O.A, Wszolek, Z.K, Delldonne, A, Dickson, D.W, Farrer, M.J
Published in Neuroscience (29.07.2007)
Published in Neuroscience (29.07.2007)
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Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice
Winner, B, Melrose, H.L, Zhao, C, Hinkle, K.M, Yue, M, Kent, C, Braithwaite, A.T, Ogholikhan, S, Aigner, R, Winkler, J, Farrer, M.J, Gage, F.H
Published in Neurobiology of disease (01.03.2011)
Published in Neurobiology of disease (01.03.2011)
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Lrrk2 localization in the primate basal ganglia and thalamus: A light and electron microscopic analysis in monkeys
Lee, H., Melrose, H.L., Yue, M., Pare, Jean-Francois, Farrer, M.J., Smith, Y.
Published in Experimental neurology (01.08.2010)
Published in Experimental neurology (01.08.2010)
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Nigrostriatal dopaminergic activities in dementia with lewy bodies in relation to neuroleptic sensitivity: comparisons with parkinson’s disease
Piggott, Margaret A, Perry, Elaine K, Marshall, Elizabeth F, McKeith, Ian G, Johnson, Mary, Melrose, Heather L, Court, Jennifer A, Lloyd, Stephen, Fairbairn, Andrew, Brown, Andrew, Thompson, Peter, Perry, Robert H
Published in Biological psychiatry (1969) (15.10.1998)
Published in Biological psychiatry (1969) (15.10.1998)
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Proteome Analysis of Highly Immunoreactive Proteins of Helicobacter pylori
Lock, Robert A., Coombs, Geoffrey W., McWilliams, Tracy M., Pearman, John W., Grubb, Warren B., Melrose, Graham J. H., Forbes, Geoffrey M.
Published in Helicobacter (Cambridge, Mass.) (01.06.2002)
Published in Helicobacter (Cambridge, Mass.) (01.06.2002)
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Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein
Hutton, Mike, Lewis, Jada, McGowan, Eileen, Rockwood, Julia, Melrose, Heather, Nacharaju, Parimala, Van Slegtenhorst, Marjon, Gwinn-Hardy, Katrina, Murphy, M. P, Baker, Matt, Yu, Xin, Duff, Karen, Hardy, John, Corral, Anthony, Lin, Wen-Lang, Yen, Shu-Hui, Dickson, Dennis W, Davies, Peter
Published in Nature genetics (01.08.2000)
Published in Nature genetics (01.08.2000)
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Proteomic analysis reveals co-ordinated alterations in protein synthesis and degradation pathways in LRRK2 knockout mice
Pellegrini, Laura, Hauser, David N, Li, Yan, Mamais, Adamantios, Beilina, Alexandra, Kumaran, Ravindran, Wetzel, Andrea, Nixon-Abell, Jonathon, Heaton, George, Rudenko, Iakov, Alkaslasi, Mor, Ivanina, Natalie, Melrose, Heather L, Cookson, Mark R, Harvey, Kirsten
Published in Human molecular genetics (15.09.2018)
Published in Human molecular genetics (15.09.2018)
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Characterisation of the 5-HT receptor binding profile of eletriptan and kinetics of [3H]eletriptan binding at human 5-HT1B and 5-HT1D receptors
NAPIER, C, STEWART, M, MELROSE, H, HOPKINS, B, MCHARG, A, WALLIS, R
Published in European journal of pharmacology (05.03.1999)
Published in European journal of pharmacology (05.03.1999)
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Monitoring Energy Levels in Chronic Fatigue Syndrome
Jason, Leonard A, Holden, John G, Taylor, Stephanie, Melrose, Harriet
Published in The Psychological record (01.10.1995)
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Published in The Psychological record (01.10.1995)
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Novel therapeutic agents
Field, M., Bramwell, S., Cox, P., Melrose, H., Offord, J., Richardson, E., Su, T., Williams, D.
Published in The journal of pain (01.04.2004)
Published in The journal of pain (01.04.2004)
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Novel therapeutic agents: The analgesic actions of pregabalin are mediated through its binding to the α 2-δ-1 subunit of voltage-gated calcium channels
Field, M., Bramwell, S., Cox, P., Melrose, H., Offord, J., Richardson, E., Su, T., Williams, D.
Published in The journal of pain (2004)
Published in The journal of pain (2004)
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