Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cell-mediated cardiac protection and functional improvement
Gnecchi, Massimiliano, He, Huamei, Noiseux, Nicolas, Liang, Olin D, Zhang, Lunan, Morello, Fulvio, Mu, Hui, Melo, Luis G, Pratt, Richard E, Ingwall, Joanne S, Dzau, Victor J
Published in The FASEB journal (01.04.2006)
Published in The FASEB journal (01.04.2006)
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Paracrine action accounts for marked protection of ischemic heart by Akt-modified mesenchymal stem cells
Dzau, Victor J, Gnecchi, Massimiliano, He, Huamei, Liang, Olin D, Melo, Luis G, Morello, Fulvio, Mu, Hui, Noiseux, Nicolas, Zhang, Lunan, Pratt, Richard E, Ingwall, Joanne S
Published in Nature medicine (01.04.2005)
Published in Nature medicine (01.04.2005)
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Early Beneficial Effects of Bone Marrow‐Derived Mesenchymal Stem Cells Overexpressing Akt on Cardiac Metabolism After Myocardial Infarction
Gnecchi, Massimiliano, He, Huamei, Melo, Luis G., Noiseux, Nicolas, Morello, Fulvio, de Boer, Rudolf A., Zhang, Lunan, Pratt, Richard E., Dzau, Victor J., Ingwall, Joanne S.
Published in Stem cells (Dayton, Ohio) (01.04.2009)
Published in Stem cells (Dayton, Ohio) (01.04.2009)
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Cytokine-induced mobilization of circulating endothelial progenitor cells enhances repair of injured arteries
DELING KONG, MELO, Luis G, GNECCHI, Massimiliano, LUNAN ZHANG, MOSTOSLAVSKY, Gustavo, LIEW, Chong C, PRATT, Richard E, DZAU, Victor J
Published in Circulation (New York, N.Y.) (05.10.2004)
Published in Circulation (New York, N.Y.) (05.10.2004)
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Therapeutic potential of endothelial progenitor cells in cardiovascular diseases
DZAU, Victor J, GNECCHI, Massimiliano, PACHORI, Alok S, MORELLO, Fulvio, MELO, Luis G
Published in Hypertension (Dallas, Tex. 1979) (01.07.2005)
Published in Hypertension (Dallas, Tex. 1979) (01.07.2005)
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Enhanced inhibition of neointimal hyperplasia by genetically engineered endothelial progenitor cells
DELING KONG, MELO, Luis G, MANGI, Abeel A, LUNAN ZHANG, LOPEZ-ILASACA, Marco, PERRELLA, Mark A, LIEW, Chong C, PRATT, Richard E, DZAU, Victor J
Published in Circulation (New York, N.Y.) (13.04.2004)
Published in Circulation (New York, N.Y.) (13.04.2004)
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Protection of Human Vascular Smooth Muscle Cells From H2O2-Induced Apoptosis Through Functional Codependence Between HO-1 and AKT
Brunt, Keith R, Fenrich, Keith K, Kiani, Gholam, Tse, M Yat, Pang, Stephen C, Ward, Christopher A, Melo, Luis G
Published in Arteriosclerosis, thrombosis, and vascular biology (01.09.2006)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.09.2006)
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Cardiac-Specific Expression of Heme Oxygenase-1 Protects Against Ischemia and Reperfusion Injury in Transgenic Mice
Yet, Shaw-Fang, Tian, Rong, Layne, Matthew D, Wang, Zhi Yuan, Maemura, Koji, Solovyeva, Maria, Ith, Bonna, Melo, Luis G, Zhang, Lunan, Ingwall, Joanne S, Dzau, Victor J, Lee, Mu-En, Perrella, Mark A
Published in Circulation research (20.07.2001)
Published in Circulation research (20.07.2001)
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Gene therapy strategy for long-term myocardial protection using adeno-associated virus-mediated delivery of heme oxygenase gene
MELO, Luis G, AGRAWAL, Reitu, YET, Shaw-Fang, LAYNE, Matthew D, PERRELLA, Mark A, DZAU, Victor J, ZHANG, Lunan, REZVANI, Mojgan, MANGI, Abeel A, EHSAN, Afshin, GRIESE, Daniel P, DELL, Giorgio, MANN, Michael J, OYAMA, Junichi
Published in Circulation (New York, N.Y.) (05.02.2002)
Published in Circulation (New York, N.Y.) (05.02.2002)
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Ex Vivo Akt/HO-1 Gene Therapy to Human Endothelial Progenitor Cells Enhances Myocardial Infarction Recovery
Brunt, Keith R., Wu, Jun, Chen, Zhilin, Poeckel, Daniel, Dercho, Ryan A., Melo, Luis G., Funk, Colin D., Ward, Christopher A., Li, Ren-Ke
Published in Cell transplantation (01.01.2012)
Published in Cell transplantation (01.01.2012)
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Preemptive heme oxygenase-1 gene delivery reveals reduced mortality and preservation of left ventricular function 1 yr after acute myocardial infarction
Liu, Xiaoli, Simpson, Jeremy A, Brunt, Keith R, Ward, Christopher A, Hall, Sean R. R, Kinobe, Robert T, Barrette, Valerie, Tse, M. Yat, Pang, Stephen C, Pachori, Alok S, Dzau, Victor J, Ogunyankin, Kofo O, Melo, Luis G
Published in American journal of physiology. Heart and circulatory physiology (01.07.2007)
Published in American journal of physiology. Heart and circulatory physiology (01.07.2007)
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Heme oxygenase-1 inhibits pro-oxidant induced hypertrophy in HL-1 cardiomyocytes
Brunt, Keith R, Tsuji, Matthew R, Lai, Joyce H, Kinobe, Robert T, Durante, William, Claycomb, William C, Ward, Christopher A, Melo, Luis G
Published in Experimental biology and medicine (Maywood, N.J.) (01.05.2009)
Published in Experimental biology and medicine (Maywood, N.J.) (01.05.2009)
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Hypoxia-Regulated Therapeutic Gene as a Preemptive Treatment Strategy against Ischemia/Reperfusion Tissue Injury
Pachori, Alok S., Melo, Luis G., Hart, Melanie L., Noiseux, Nicholas, Zhang, Lunan, Morello, Fulvio, Solomon, Scott D., Stahl, Gregory L., Pratt, Richard E., Dzau, Victor J., Braunwald, Eugene
Published in Proceedings of the National Academy of Sciences - PNAS (17.08.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (17.08.2004)
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Chronic Recurrent Myocardial Ischemic Injury Is Significantly Attenuated by Pre-Emptive Adeno-Associated Virus Heme Oxygenase-1 Gene Delivery
Pachori, Alok S., Melo, Luis G., Zhang, Lunan, Solomon, Scott D., Dzau, Victor J.
Published in Journal of the American College of Cardiology (07.02.2006)
Published in Journal of the American College of Cardiology (07.02.2006)
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Targeted Migration of Mesenchymal Stem Cells Modified With CXCR4 Gene to Infarcted Myocardium Improves Cardiac Performance
Cheng, Zhaokang, Ou, Lailiang, Zhou, Xin, Li, Fei, Jia, Xiaohua, Zhang, Yinguo, Liu, Xiaolei, Li, Yuming, Ward, Christopher A, Melo, Luis G, Kong, Deling
Published in Molecular therapy (01.03.2008)
Published in Molecular therapy (01.03.2008)
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Heme-oxygenase-1-induced protection against hypoxia/reoxygenation is dependent on biliverdin reductase and its interaction with PI3K/Akt pathway
Pachori, Alok S, Smith, Anthony, McDonald, Patricia, Zhang, Lunan, Dzau, Victor J, Melo, Luis G
Published in Journal of molecular and cellular cardiology (01.11.2007)
Published in Journal of molecular and cellular cardiology (01.11.2007)
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Isolation and transplantation of autologous circulating endothelial cells into denuded vessels and prosthetic grafts: Implications for cell-based vascular therapy
GRIESE, Daniel P, EHSAN, Afshin, MELO, Luis G, DELING KONG, LUNAN ZHANG, MANN, Michael J, PRATT, Richard E, MULLIGAN, Richard C, DZAU, Victor J
Published in Circulation (New York, N.Y.) (25.11.2003)
Published in Circulation (New York, N.Y.) (25.11.2003)
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Heme oxygenase-1 overexpression exacerbates heart failure with aging and pressure overload but is protective against isoproterenol-induced cardiomyopathy in mice
Allwood, Melissa A, Kinobe, Robert T, Ballantyne, Laurel, Romanova, Nadya, Melo, Luis G, Ward, Christopher A, Brunt, Keith R, Simpson, Jeremy A
Published in Cardiovascular pathology (01.07.2014)
Published in Cardiovascular pathology (01.07.2014)
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