Antibody Therapeutics in Cancer
Sliwkowski, Mark X., Mellman, Ira
Published in Science (American Association for the Advancement of Science) (13.09.2013)
Published in Science (American Association for the Advancement of Science) (13.09.2013)
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Journal Article
IL-1 and IL-1ra are key regulators of the inflammatory response to RNA vaccines
Tahtinen, Siri, Tong, Ann-Jay, Himmels, Patricia, Oh, Jaehak, Paler-Martinez, Andres, Kim, Leesun, Wichner, Sara, Oei, Yoko, McCarron, Mark J., Freund, Emily C., Amir, Zhainib Adel, de la Cruz, Cecile C., Haley, Benjamin, Blanchette, Craig, Schartner, Jill M., Ye, Weilan, Yadav, Mahesh, Sahin, Ugur, Delamarre, Lélia, Mellman, Ira
Published in Nature immunology (01.04.2022)
Published in Nature immunology (01.04.2022)
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Journal Article
Molecular determinants of response to PD-L1 blockade across tumor types
Banchereau, Romain, Leng, Ning, Zill, Oliver, Sokol, Ethan, Liu, Gengbo, Pavlick, Dean, Maund, Sophia, Liu, Li-Fen, Kadel, Edward, Baldwin, Nicole, Jhunjhunwala, Suchit, Nickles, Dorothee, Assaf, Zoe June, Bower, Daniel, Patil, Namrata, McCleland, Mark, Shames, David, Molinero, Luciana, Huseni, Mahrukh, Sanjabi, Shomyseh, Cummings, Craig, Mellman, Ira, Mariathasan, Sanjeev, Hegde, Priti, Powles, Thomas
Published in Nature communications (25.06.2021)
Published in Nature communications (25.06.2021)
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Journal Article
Spatial control of EGF receptor activation by reversible dimerization on living cells
Chung, Inhee, Akita, Robert, Vandlen, Richard, Toomre, Derek, Schlessinger, Joseph, Mellman, Ira
Published in Nature (London) (01.04.2010)
Published in Nature (London) (01.04.2010)
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Journal Article
Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients
Herbst, Roy S., Soria, Jean-Charles, Kowanetz, Marcin, Fine, Gregg D., Hamid, Omid, Gordon, Michael S., Sosman, Jeffery A., McDermott, David F., Powderly, John D., Gettinger, Scott N., Kohrt, Holbrook E. K., Horn, Leora, Lawrence, Donald P., Rost, Sandra, Leabman, Maya, Xiao, Yuanyuan, Mokatrin, Ahmad, Koeppen, Hartmut, Hegde, Priti S., Mellman, Ira, Chen, Daniel S., Hodi, F. Stephen
Published in Nature (London) (27.11.2014)
Published in Nature (London) (27.11.2014)
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Journal Article
Genetic variation associated with thyroid autoimmunity shapes the systemic immune response to PD-1 checkpoint blockade
Khan, Zia, Hammer, Christian, Carroll, Jonathan, Di Nucci, Flavia, Acosta, Sergio Ley, Maiya, Vidya, Bhangale, Tushar, Hunkapiller, Julie, Mellman, Ira, Albert, Matthew L., McCarthy, Mark I., Chandler, G. Scott
Published in Nature communications (07.06.2021)
Published in Nature communications (07.06.2021)
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Journal Article
Single-cell analysis of human non-small cell lung cancer lesions refines tumor classification and patient stratification
Leader, Andrew M., Grout, John A., Maier, Barbara B., Nabet, Barzin Y., Park, Matthew D., Tabachnikova, Alexandra, Chang, Christie, Walker, Laura, Lansky, Alona, Le Berichel, Jessica, Troncoso, Leanna, Malissen, Nausicaa, Davila, Melanie, Martin, Jerome C., Magri, Giuliana, Tuballes, Kevin, Zhao, Zhen, Petralia, Francesca, Samstein, Robert, D’Amore, Natalie Roy, Thurston, Gavin, Kamphorst, Alice O., Wolf, Andrea, Flores, Raja, Wang, Pei, Müller, Sören, Mellman, Ira, Beasley, Mary Beth, Salmon, Hélène, Rahman, Adeeb H., Marron, Thomas U., Kenigsberg, Ephraim, Merad, Miriam
Published in Cancer cell (13.12.2021)
Published in Cancer cell (13.12.2021)
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Tumour and host cell PD-L1 is required to mediate suppression of anti-tumour immunity in mice
Lau, Janet, Cheung, Jeanne, Navarro, Armando, Lianoglou, Steve, Haley, Benjamin, Totpal, Klara, Sanders, Laura, Koeppen, Hartmut, Caplazi, Patrick, McBride, Jacqueline, Chiu, Henry, Hong, Rebecca, Grogan, Jane, Javinal, Vincent, Yauch, Robert, Irving, Bryan, Belvin, Marcia, Mellman, Ira, Kim, Jeong M., Schmidt, Maike
Published in Nature communications (21.02.2017)
Published in Nature communications (21.02.2017)
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Journal Article
Transposable element expression in tumors is associated with immune infiltration and increased antigenicity
Kong, Yu, Rose, Christopher M., Cass, Ashley A., Williams, Alexander G., Darwish, Martine, Lianoglou, Steve, Haverty, Peter M., Tong, Ann-Jay, Blanchette, Craig, Albert, Matthew L., Mellman, Ira, Bourgon, Richard, Greally, John, Jhunjhunwala, Suchit, Chen-Harris, Haiyin
Published in Nature communications (19.11.2019)
Published in Nature communications (19.11.2019)
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Journal Article
Germline genetic polymorphisms influence tumor gene expression and immune cell infiltration
Lim, Yoong Wearn, Chen-Harris, Haiyin, Mayba, Oleg, Lianoglou, Steve, Wuster, Arthur, Bhangale, Tushar, Khan, Zia, Mariathasan, Sanjeev, Daemen, Anneleen, Reeder, Jens, Haverty, Peter M., Forrest, William F., Brauer, Matthew, Mellman, Ira, Albert, Matthew L.
Published in Proceedings of the National Academy of Sciences - PNAS (11.12.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (11.12.2018)
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Journal Article
Polygenic risk for skin autoimmunity impacts immune checkpoint blockade in bladder cancer
Khan, Zia, Di Nucci, Flavia, Kwan, Antonia, Hammer, Christian, Mariathasan, Sanjeev, Rouilly, Vincent, Carroll, Jonathan, Fontes, Magnus, Acosta, Sergio Ley, Guardino, Ellie, Chen-Harris, Haiyin, Bhangale, Tushar, Mellman, Ira, Rosenberg, Jonathan, Powles, Thomas, Hunkapiller, Julie, Chandler, G. Scott, Albert, Matthew L.
Published in Proceedings of the National Academy of Sciences - PNAS (02.06.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (02.06.2020)
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Journal Article
The Prioritization of Cancer Antigens: A National Cancer Institute Pilot Project for the Acceleration of Translational Research
CHEEVER, Martin A, ALLISON, James P, MATRISIAN, Lynn M, FERRIS, Andrea S, FINN, Olivera J, HASTINGS, Benjamin M, HECHT, Toby T, MELLMAN, Ira, PRINDIVILLE, Sheila A, VINER, Jaye L, WEINER, Louis M
Published in Clinical cancer research (01.09.2009)
Published in Clinical cancer research (01.09.2009)
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Journal Article
Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity
Maurer, Till, Garrenton, Lindsay S, Oh, Angela, Pitts, Keith, Anderson, Daniel J, Skelton, Nicholas J, Fauber, Benjamin P, Pan, Borlan, Malek, Shiva, Stokoe, David, Ludlam, Mary J. C, Bowman, Krista K, Wu, Jiansheng, Giannetti, Anthony M, Starovasnik, Melissa A, Mellman, Ira, Jackson, Peter K, Rudolph, Joachim, Wang, Weiru, Fang, Guowei
Published in Proceedings of the National Academy of Sciences - PNAS (03.04.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (03.04.2012)
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Journal Article
Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation
Vander Lugt, Bryan, Khan, Aly A, Hackney, Jason A, Agrawal, Smita, Lesch, Justin, Zhou, Meijuan, Lee, Wyne P, Park, Summer, Xu, Min, DeVoss, Jason, Spooner, Chauncey J, Chalouni, Cecile, Delamarre, Lelia, Mellman, Ira, Singh, Harinder
Published in Nature immunology (01.02.2014)
Published in Nature immunology (01.02.2014)
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Journal Article
Transcriptional determinants of tolerogenic and immunogenic states during dendritic cell maturation
Vander Lugt, Bryan, Riddell, Jeremy, Khan, Aly A, Hackney, Jason A, Lesch, Justin, DeVoss, Jason, Weirauch, Matthew T, Singh, Harinder, Mellman, Ira
Published in The Journal of cell biology (06.03.2017)
Published in The Journal of cell biology (06.03.2017)
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