Abstract 1025: Genomic and metabolomic analysis of MAT2A inhibition reveals increased RNA splicing, lipid metabolism and cell cycle arrest in MTAP deleted tumor models
Bhola, Neil, Givmanesh, Atieh, Faulhaber, John, Fleury, Melissa, Lackner, Mark, Mounir, Zineb, Pankajakshan, Divya
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Abstract 1956: In vitro and in vivo characterization of novel MAT2A allosteric inhibitors
Pei, Zhonghua, Alam, Muzaffar, Bhola, Neil, Cleary, Leah, Drummond, Jake, Fisher, Marcus, Fleury, Melissa, Garcia, Candy, Givmanesh, Atieh, Linghu, Xin, McSpadden, Ethan, Mounir, Zineb, Neilan, Claire, Newby, Zach, Perumal, Senthil, Steel, Richard, Sutton, James, Vaidya, Kedar, Wagle, Marie-Claire, Wang, Jianhong, Yao, Bing, Lackner, Mark, Dillon, Michael P.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Abstract 1644: Dual inhibition of MAT2A and PRMT5 delivers synergistic anti-tumor responses in preclinical models of MTAP -deleted cancer
Fischer, Marcus M., Gerrick, Kimberline, Belmontes, Brian, Slemmons, Katherine, Freyman, Yevgeniy, Jain, Jay, Federowicz, Steve, Bishof, Isaac, Rao, Arjun A., Fleury, Melissa, Mounir, Zineb, Lackner, Mark R., Hughes, Paul E., White, Mike, Neilan, Claire L.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Abstract 19056: Discovery of Potent and Selective Neprilysin Inhibitors Exhibiting Sustained Pharmacodynamic Activity and Non-renal Elimination in Rats
Bourdet, David L, McNamara, Alex, Hill, Craig, DeMent, Kevin, Fleury, Melissa, Yu, Cecile, Hegde, Laxminarayan G, Martin, William, Hegde, Sharath, Klein, Uwe, Hughes, Adam D
Published in Circulation (New York, N.Y.) (10.11.2015)
Published in Circulation (New York, N.Y.) (10.11.2015)
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Abstract 1628: A small-molecule inhibitor of WRN selectively kills MSI-H cancer cells and phenocopies WRN genetic defects
Rao, Yanhua, Srivatsan, Anjana, Liimatta, Marya, Munoz, Diana, Quirit, Jeanne, Shi, Jianxia, Nguyen, An, Linghu, Xin, Federowicz, Federowicz, Jones, Brian, Fleury, Melissa, Newby, Zach, Dillon, Michael P., Barsanti, Paul A., Lackner, Mark R., White, Michael A., Lee, Yang, Landis, Phil, Peng, Yang, Cicchini, Michelle, Cottom, Josh, Nickels, Leng, Brnardic, Ed, DeMartino, Michael, Taygerly, Josh
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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NAPHTHYRIDINE COMPOUNDS AS JAK KINASE INHIBITORS
DANTE D PODESTO, JENNIFER KOZAK, MELISSA FLEURY, HUANG XIAOJUN, VENKAT R THALLADI, RYAN HUDSON, GARY E L BLANT, ANNE-MARIE BEAUSOLEIL, FATHEREE PAUL R
Year of Publication 01.07.2021
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Year of Publication 01.07.2021
Patent
NAPHTHYRIDINE COMPOUNDS AS JAK KINASE INHIBITORS
DANTE D PODESTO, JENNIFER KOZAK, MELISSA FLEURY, HUANG XIAOJUN, VENKAT R THALLADI, RYAN HUDSON, GARY E L BLANT, ANNE-MARIE BEAUSOLEIL, FATHEREE PAUL R
Year of Publication 07.01.2021
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Year of Publication 07.01.2021
Patent
5-BIPHENYL-4-HETEROARYLCARBONYLAMINO-PENTANOIC ACID DERIVATIVES AS NEPRILYSIN INHIBITORS
MELISSA FLEURY, DONNA A A WILTON, LONG DANIEL D, ADAM D HUGHES, ANNE-MARIE BEAUSOLEIL
Year of Publication 20.12.2018
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Year of Publication 20.12.2018
Patent
NEPRILYSIN INHIBITORS
MELISSA FLEURY, DONNA A A WILTON, LONG DANIEL D, ADAM D HUGHES, ANNE-MARIE BEAUSOLEIL
Year of Publication 20.12.2018
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Year of Publication 20.12.2018
Patent
NAPHTHYRIDINE COMPOUNDS AS JAK KINASE INHIBITORS
DANTE D PODESTO, JENNIFER KOZAK, MELISSA FLEURY, HUANG XIAOJUN, VENKAT R THALLADI, RYAN HUDSON, GARY E L BLANT, ANNE-MARIE BEAUSOLEIL, FATHEREE PAUL R
Year of Publication 27.07.2020
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Year of Publication 27.07.2020
Patent