Novel Delivery of SN38 Markedly Inhibits Tumor Growth in Xenografts, Including a Camptothecin-11–Refractory Model
SAPRA, Puja, HONG ZHAO, MEHLIG, Mary, MALABY, Jennifer, KRAFT, Patricia, LONGLEY, Clifford, GREENBERGER, Lee M, HORAK, Ivan D
Published in Clinical cancer research (15.03.2008)
Published in Clinical cancer research (15.03.2008)
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Antitumor activity of poly(ethylene glycol)–camptothecin conjugate: The inhibition of tumor growth in vivo
Yu, Deshan, Peng, Ping, Dharap, Sonia S., Wang, Yang, Mehlig, Mary, Chandna, Pooja, Zhao, Hong, Filpula, David, Yang, Karen, Borowski, Virna, Borchard, Gerrit, Zhang, Zhihua, Minko, Tamara
Published in Journal of controlled release (10.12.2005)
Published in Journal of controlled release (10.12.2005)
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Marked therapeutic efficacy of a novel polyethylene glycol-SN38 conjugate, EZN-2208, in xenograft models of B-cell non-Hodgkin's lymphoma
Sapra, Puja, Kraft, Patricia, Mehlig, Mary, Malaby, Jennifer, Zhao, Hong, Greenberger, Lee M, Horak, Ivan D
Published in Haematologica (Roma) (01.10.2009)
Published in Haematologica (Roma) (01.10.2009)
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Potent and sustained inhibition of HIF-1α and downstream genes by a polyethyleneglycol-SN38 conjugate, EZN-2208, results in anti-angiogenic effects
Sapra, Puja, Kraft, Patricia, Pastorino, Fabio, Ribatti, Domenico, Dumble, Melissa, Mehlig, Mary, Wang, Maoliang, Ponzoni, Mirco, Greenberger, Lee M., Horak, Ivan D.
Published in Angiogenesis (London) (01.09.2011)
Published in Angiogenesis (London) (01.09.2011)
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Structure-function engineering of interferon-beta-1b for improving stability, solubility, potency, immunogenicity, and pharmacokinetic properties by site-selective mono-PEGylation
Basu, Amartya, Yang, Karen, Wang, Maoliang, Liu, Sam, Chintala, Ramesh, Palm, Thomas, Zhao, Hong, Peng, Ping, Wu, Dechun, Zhang, Zhenfan, Hua, Jack, Hsieh, Ming-Ching, Zhou, John, Petti, Gerald, Li, Xiguang, Janjua, Ahsen, Mendez, Magda, Liu, Jun, Longley, Clifford, Zhang, Zhihua, Mehlig, Mary, Borowski, Virna, Viswanathan, Manickam, Filpula, David
Published in Bioconjugate chemistry (01.05.2006)
Published in Bioconjugate chemistry (01.05.2006)
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Potent and sustained inhibition of HIF-1[alpha] and downstream genes by a polyethyleneglycol-SN38 conjugate, EZN-2208, results in anti-angiogenic effects
Sapra, Puja, Kraft, Patricia, Pastorino, Fabio, Ribatti, Domenico, Dumble, Melissa, Mehlig, Mary, Wang, Maoliang, Ponzoni, Mirco, Greenberger, Lee M, Horak, Ivan D
Published in Angiogenesis (London) (01.09.2011)
Published in Angiogenesis (London) (01.09.2011)
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Tailoring structure-function and pharmacokinetic properties of single-chain Fv proteins by site-specific PEGylation
Yang, Karen, Basu, Amartya, Wang, Maoliang, Chintala, Ramesh, Hsieh, Ming-Ching, Liu, Sam, Hua, Jack, Zhang, Zhenfan, Zhou, John, Li, Mark, Phyu, Hnin, Petti, Gerald, Mendez, Magda, Janjua, Haleema, Peng, Ping, Longley, Clifford, Borowski, Virna, Mehlig, Mary, Filpula, David
Published in Protein engineering (01.10.2003)
Published in Protein engineering (01.10.2003)
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Marked Therapeutic Efficacy of a Novel Polyethyleneglycol-SN38 Conjugate, EZN-2208, in Xenograft Models of Non-Hodgkin's Lymphoma
Sapra, Puja, Mehlig, Mary, Malaby, Jennifer, Kraft, Patricia, Longley, Clifford, Zhao, Hong, Greenberger, Lee M., Horak, Ivan D.
Published in Blood (16.11.2007)
Published in Blood (16.11.2007)
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Recombinant Human Mannose-Binding Lectin (rhMBL) Binds to Human and Mouse Cancer Cells and Elicits Antitumor Activity in a MBL Knockout Mouse Model of Murine Cancer
Sapra, Puja, Kraft, Patricia, Mehlig, Mary, Zhang, Zhihua, Greenberger, Lee M., Horak, Ivan D.
Published in Blood (16.11.2006)
Published in Blood (16.11.2006)
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Engineering an Arginine Catabolizing Bioconjugate: Biochemical and Pharmacological Characterization of PEGylated Derivatives of Arginine Deiminase from Mycoplasma arthritidis
Wang, Maoliang, Basu, Amartya, Palm, Thomas, Hua, Jack, Youngster, Stephen, Hwang, Lisa, Liu, Hsien-Ching, Li, Xiguang, Peng, Ping, Zhang, Yue, Zhao, Hong, Zhang, Zhihua, Longley, Clifford, Mehlig, Mary, Borowski, Virna, Sai, Prakash, Viswanathan, Manickam, Jang, Eun, Petti, Gerald, Liu, Sam, Yang, Karen, Filpula, David
Published in Bioconjugate chemistry (01.11.2006)
Published in Bioconjugate chemistry (01.11.2006)
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Delivery of G3139 using releasable PEG-linkers: Impact on pharmacokinetic profile and anti-tumor efficacy
Zhao, Hong, Peng, Ping, Longley, Clifford, Zhang, Yue, Borowski, Virna, Mehlig, Mary, Reddy, Prasanna, Xia, Jing, Borchard, Gerrit, Lipman, Jack, Benimetskaya, Luba, Stein, C.A.
Published in Journal of controlled release (01.06.2007)
Published in Journal of controlled release (01.06.2007)
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Journal Article
Engineering an Arginine Catabolizing Bioconjugate: Biochemical and Pharmacological Characterization of PEGylated Derivatives of Arginine Deiminase from Mycoplasma arthritidis
Wang, Maoliang, Basu, Amartya, Palm, Thomas, Hua, Jack, Youngster, Stephen, Hwang, Lisa, Liu, Hsien-Ching, Li, Xiguang, Peng, Ping, Zhang, Yue, Zhao, Hong, Zhang, Zhihua, Longley, Clifford, Mehlig, Mary, Borowski, Virna, Sai, Prakash, Viswanathan, Manickam, Jang, Eun, Petti, Gerald, Liu, Sam, Yang, Karen, Filpula, David
Published in Bioconjugate chemistry (21.03.2007)
Published in Bioconjugate chemistry (21.03.2007)
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Structure−Function Engineering of Interferon-β-1b for Improving Stability, Solubility, Potency, Immunogenicity, and Pharmacokinetic Properties by Site-Selective Mono-PEGylation
Basu, Amartya, Yang, Karen, Wang, Maoliang, Liu, Sam, Chintala, Ramesh, Palm, Thomas, Zhao, Hong, Peng, Ping, Wu, Dechun, Zhang, Zhenfan, Hua, Jack, Hsieh, Ming-Ching, Zhou, John, Petti, Gerald, Li, Xiguang, Janjua, Ahsen, Mendez, Magda, Liu, Jun, Longley, Clifford, Zhang, Zhihua, Mehlig, Mary, Borowski, Virna, Viswanathan, Manickam, Filpula, David
Published in Bioconjugate chemistry (17.05.2006)
Published in Bioconjugate chemistry (17.05.2006)
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Anticancer drug delivery systems: multi-loaded N4-acyl poly(ethylene glycol) prodrugs of ara-C. : II. Efficacy in ascites and solid tumors
Choe, Yun H, Conover, Charles D, Wu, Dechun, Royzen, Maksim, Gervacio, Yoany, Borowski, Virna, Mehlig, Mary, Greenwald, Richard B
Published in Journal of controlled release (19.02.2002)
Published in Journal of controlled release (19.02.2002)
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